Novel immunological approach to asses donor reactivity of transplant recipients using a humanized mouse model.
暂无分享,去创建一个
R. Goto | M. Zaitsu | T. Shimamura | A. Taketomi | S. Emoto | M. Fukai | Masaaki Watanabe | Yoshikazu Ganchiku | N. Kawamura | Yasutomo Fukasaku | Shin Emoto
[1] Sabine Tischer-Zimmermann,et al. Robust Identification of Suitable T-Cell Subsets for Personalized CMV-Specific T-Cell Immunotherapy Using CD45RA and CD62L Microbeads , 2019, International journal of molecular sciences.
[2] S. Sidhu,et al. Humanized Mice for the Study of Immuno-Oncology. , 2018, Trends in immunology.
[3] S. Fujiwara,et al. Comprehensive Analysis of the Activation and Proliferation Kinetics and Effector Functions of Human Lymphocytes, and Antigen Presentation Capacity of Antigen-Presenting Cells in Xenogeneic Graft-Versus-Host Disease. , 2018, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[4] M. Zaitsu,et al. Selective blockade of CD28 on human T cells facilitates regulation of alloimmune responses. , 2017, JCI insight.
[5] Mamoru Ito,et al. A Novel Xenogeneic Graft‐Versus‐Host Disease Model for Investigating the Pathological Role of Human CD4+ or CD8+ T Cells Using Immunodeficient NOG Mice , 2017, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[6] Jang-Gi Choi,et al. Combination of IL-10 and IL-2 induces oligoclonal human CD4 T cell expansion during xenogeneic and allogeneic GVHD in humanized mice , 2017, Heliyon.
[7] D. Greiner,et al. Humanized Mouse Models of Clinical Disease. , 2017, Annual review of pathology.
[8] A. Haverich,et al. In Vivo Development of Transplant Arteriosclerosis in Humanized Mice Reflects Alloantigen Recognition and Peripheral Treg Phenotype of Lung Transplant Recipients , 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[9] F. Emmrich,et al. Attenuation of graft‐versus‐host‐disease in NOD scid IL‐2Rγ−/− (NSG) mice by ex vivo modulation of human CD4+ T cells , 2016, Cytometry. Part A : the journal of the International Society for Analytical Cytology.
[10] S. Todo,et al. A pilot study of operational tolerance with a regulatory T‐cell‐based cell therapy in living donor liver transplantation , 2016, Hepatology.
[11] D. Schoenfeld,et al. Induced regulatory T cells in allograft tolerance via transient mixed chimerism. , 2016, JCI insight.
[12] D. Greiner,et al. Humanized Mouse Models for Transplant Immunology , 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[13] Paul L. Martin,et al. Infectious Complications After Liver Transplantation. , 2015, Gastroenterology & hepatology.
[14] S. Newbigging,et al. Humanized Chronic Graft-versus-Host Disease in NOD-SCID il2rγ-/- (NSG) Mice with G-CSF-Mobilized Peripheral Blood Mononuclear Cells following Cyclophosphamide and Total Body Irradiation , 2015, PloS one.
[15] Jang-Gi Choi,et al. IL-10 exacerbates xenogeneic GVHD by inducing massive human T cell expansion. , 2015, Clinical immunology.
[16] Sang Il Kim. Bacterial infection after liver transplantation. , 2014, World journal of gastroenterology.
[17] R. Lechler,et al. Ex Vivo Expanded Human Regulatory T Cells Delay Islet Allograft Rejection via Inhibiting Islet-Derived Monocyte Chemoattractant Protein-1 Production in CD34+ Stem Cells-Reconstituted NOD-scid IL2rγnull Mice , 2014, PloS one.
[18] K. Wood,et al. Ex Vivo Expanded Human Regulatory T Cells Can Prolong Survival of a Human Islet Allograft in a Humanized Mouse Model , 2013, Transplantation.
[19] P. V. D. van de Kerkhof,et al. Humanized Mouse Model of Skin Inflammation Is Characterized by Disturbed Keratinocyte Differentiation and Influx of IL-17A Producing T Cells , 2012, PloS one.
[20] F. Nestle,et al. Xenogeneic Graft-versus-Host-Disease in NOD-scid IL-2Rγnull Mice Display a T-Effector Memory Phenotype , 2012, PloS one.
[21] H. Ohdan,et al. Optimization of immunosuppressive therapy based on a multiparametric mixed lymphocyte reaction assay reduces infectious complications and mortality in living donor liver transplant recipients. , 2012, Transplantation proceedings.
[22] J. Delrow,et al. Rescued Tolerant CD8 T Cells Are Preprogrammed to Reestablish the Tolerant State , 2012, Science.
[23] Kathryn J Wood,et al. Mechanisms of rejection: current perspectives. , 2012, Transplantation.
[24] P. Ye,et al. Dynamic changes in Th1, Th17, and FoxP3+ T cells in patients with acute cellular rejection after cardiac transplantation , 2011, Clinical transplantation.
[25] R. Goto,et al. Ex Vivo–Expanded Human Regulatory T Cells Prevent the Rejection of Skin Allografts in a Humanized Mouse Model , 2010, Transplantation.
[26] M. Roth,et al. Reconstitution of huPBL-NSG Mice with Donor-Matched Dendritic Cells Enables Antigen-Specific T-cell Activation , 2010, Journal of Neuroimmune Pharmacology.
[27] T. Starzl,et al. Themes of liver transplantation , 2010, Hepatology.
[28] K. Wood,et al. In vivo Prevention of Transplant Arteriosclerosis by ex vivo Expanded Human Regulatory T Cells , 2010, Nature Medicine.
[29] Raymond Dunn,et al. NOD-scid IL2r&ggr;null Mouse Model of Human Skin Transplantation and Allograft Rejection , 2010, Transplantation.
[30] D. Greiner,et al. Human peripheral blood leucocyte non‐obese diabetic‐severe combined immunodeficiency interleukin‐2 receptor gamma chain gene mouse model of xenogeneic graft‐versus‐host‐like disease and the role of host major histocompatibility complex , 2009, Clinical and experimental immunology.
[31] Graham M Lord,et al. Relative roles of Th1 and Th17 effector cells in allograft rejection , 2009, Current opinion in organ transplantation.
[32] C. Mathieu,et al. Relevance of cytotoxic alloreactivity under different immunosuppressive regimens in clinical islet cell transplantation , 2008, Clinical and experimental immunology.
[33] K. Brown,et al. Homeostatic Proliferation of Lymphocytes Results in Augmented Memory-Like Function and Accelerated Allograft Rejection1 , 2008, The Journal of Immunology.
[34] R. Woodland,et al. A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene. , 2008, Clinical immunology.
[35] A. Matas,et al. Pretransplant Donor-Specific and Non-Specific Immune Parameters Associated With Early Acute Rejection , 2008, Transplantation.
[36] J. Pober,et al. Human Effector Memory CD4+ T Cells Directly Recognize Allogeneic Endothelial Cells In Vitro and In Vivo , 2007, The Journal of Immunology.
[37] R. Lechler,et al. Allorecognition and the alloresponse: clinical implications. , 2007, Tissue antigens.
[38] Y. Matsuzaki,et al. Spleen Plays an Important Role in Maintaining Tolerance After Removal of the Vascularized Heart Graft , 2007, Transplantation.
[39] Dale L. Greiner,et al. Humanized mice in translational biomedical research , 2007, Nature Reviews Immunology.
[40] J. Janosky,et al. Enhanced Donor‐Specific Alloreactivity Occurs Independently of Immunosuppression in Children with Early Liver Rejection , 2005, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[41] J. Mir,et al. De Novo Internal Neoplasms after Liver Transplantation: Increased Risk and Aggressive Behavior in Recent Years? , 2004, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[42] William R. Burns,et al. Interferon‐γ plays a nonredundant role in mediating T‐cell‐ dependent outward vascular remodeling of allogeneic human coronary arteries , 2004 .
[43] J. Markmann,et al. Homeostatic proliferation is a barrier to transplantation tolerance , 2004, Nature Medicine.
[44] C. Magee,et al. The growing problem of chronic renal failure after transplantation of a nonrenal organ. , 2003, The New England journal of medicine.
[45] B. Stockinger,et al. Involvement of Avidity for Major Histocompatibility Complex in Homeostasis of Naive and Memory T Cells , 2003, The Journal of experimental medicine.
[46] H. Gudmundsdottir,et al. A Closer Look at Homeostatic Proliferation of CD4+ T Cells: Costimulatory Requirements and Role in Memory Formation1 , 2001, The Journal of Immunology.
[47] F. Powrie,et al. Control of intestinal inflammation by regulatory T cells , 2001, Immunological reviews.
[48] B. Woda,et al. Regulation of Human Cell Engraftment and Development of EBV-Related Lymphoproliferative Disorders in Hu-PBL-scid Mice1 , 2000, The Journal of Immunology.
[49] J. Pober,et al. Human allogeneic vascular rejection after arterial transplantation and peripheral lymphoid reconstitution in severe combined immunodeficient mice. , 1999, Transplantation.
[50] S. Chung,et al. Donor-specific stimulation of peripheral blood mononuclear cells from recipients of orthotopic liver transplants is associated, in the absence of rejection, with type-2 cytokine production. , 1998, Immunology letters.
[51] A. del Palacio,et al. Lipid abnormalities in stable liver transplant recipients – effects of cyclosporin, tacrolimus, and steroids , 1998, Transplant international : official journal of the European Society for Organ Transplantation.
[52] H. Noreen,et al. Lack of correlation of MLC reactivity with acute graft-versus-host disease and mortality in unrelated donor bone marrow transplantation. , 1996, Human immunology.
[53] A. Morris,et al. Clinical significance of in vitro donor‐specific hyporesponsiveness in renal allograft recipients as demonstrated by the MLR , 1994, Transplant international : official journal of the European Society for Organ Transplantation.
[54] F. Ramsdell,et al. Maintenance of in Vivo Tolerance by Persistence of Antigen , 1992, Science.
[55] D. Dunn,et al. CYCLOSPORIN A INITIALLY AS THE ONLY IMMUNOSUPPRESSANT IN 34 RECIPIENTS OF CADAVERIC ORGANS: 32 KIDNEYS, 2 PANCREASES, AND 2 LIVERS , 1979, The Lancet.