Emerging roles of DNA tumor viruses in cell proliferation: new insights into genomic instability

[1]  Dale L Boger,et al.  Discovering potent and selective reversible inhibitors of enzymes in complex proteomes , 2003, Nature Biotechnology.

[2]  Patrick A. Eyers,et al.  A Novel Mechanism for Activation of the Protein Kinase Aurora A , 2003, Current Biology.

[3]  S. Frank Somatic Mutation: Early Cancer Steps Depend on Tissue Architecture , 2003, Current Biology.

[4]  J. Dagorn,et al.  Gene expression profiling by DNA microarray analysis in mouse embryonic fibroblasts transformed by rasV12 mutated protein and the E1A oncogene , 2003, Molecular Cancer.

[5]  Karsten Weis,et al.  Regulating Access to the Genome Nucleocytoplasmic Transport throughout the Cell Cycle , 2003, Cell.

[6]  J. Pines,et al.  Active cyclin B1–Cdk1 first appears on centrosomes in prophase , 2003, Nature Cell Biology.

[7]  D. Galloway,et al.  Mechanisms by which DNA tumor virus oncoproteins target the Rb family of pocket proteins. , 2003, Carcinogenesis.

[8]  T. Kapoor,et al.  hTPX2 Is Required for Normal Spindle Morphology and Centrosome Integrity during Vertebrate Cell Division , 2002, Current Biology.

[9]  K. Schmeichel Centrosome cycle studies reveal promising candidates for anti-cancer drug design , 2002, Breast Cancer Research.

[10]  M. Winey,et al.  Centrosomes and tumour suppressors. , 2002, Current opinion in cell biology.

[11]  A. Giordano,et al.  Cell Cycle Inhibitors in Cancer Therapy , 2002 .

[12]  Erich A. Nigg,et al.  Centrosome aberrations: cause or consequence of cancer progression? , 2002, Nature Reviews Cancer.

[13]  R. Pepperkok,et al.  Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells , 2002, Nature Cell Biology.

[14]  K. Münger,et al.  Human papillomaviruses and centrosome duplication errors: modeling the origins of genomic instability , 2002, Oncogene.

[15]  W. Lingle,et al.  Centrosome amplification and the development of cancer , 2002, Oncogene.

[16]  W. Moore,et al.  Targeting of RCC1 to Chromosomes Is Required for Proper Mitotic Spindle Assembly in Human Cells , 2002, Current Biology.

[17]  R. Schlegel,et al.  Insulin-like growth factor-binding protein 3 expression increases during immortalization of cervical keratinocytes by human papillomavirus type 16 E6 and E7 proteins. , 2002, The American journal of pathology.

[18]  M. Dasso The Ran GTPase: Theme and Variations , 2002, Current Biology.

[19]  R. Margolis,et al.  Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[20]  M. Hetzer,et al.  The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly , 2002, Nature Cell Biology.

[21]  S. Frisch,et al.  Adenovirus-5 E1A: paradox and paradigm , 2002, Nature Reviews Molecular Cell Biology.

[22]  J. Raff Centrosomes and cancer: lessons from a TACC. , 2002, Trends in cell biology.

[23]  M. Pavliv,et al.  Cancer therapy utilizing an adenoviral vector expressing only E1A , 2002, Cancer Gene Therapy.

[24]  J. Pines,et al.  Cyclin A- and cyclin E-Cdk complexes shuttle between the nucleus and the cytoplasm. , 2002, Molecular biology of the cell.

[25]  P. Meraldi,et al.  Aurora‐A overexpression reveals tetraploidization as a major route to centrosome amplification in p53−/− cells , 2002, The EMBO journal.

[26]  E. White Regulation of the cell cycle and apoptosis by the oncogenes of adenovirus , 2001, Oncogene.

[27]  Karl Münger,et al.  Biological activities and molecular targets of the human papillomavirus E7 oncoprotein , 2001, Oncogene.

[28]  A. Turnell,et al.  Adenovirus E1A: remodelling the host cell, a life or death experience , 2001, Oncogene.

[29]  K. Rundell,et al.  Overexpression of Simian Virus 40 Small-T Antigen Blocks Centrosome Function and Mitotic Progression in Human Fibroblasts , 2001, Journal of Virology.

[30]  Allan Balmain,et al.  Cancer genetics: from Boveri and Mendel to microarrays , 2001, Nature Reviews Cancer.

[31]  P. Clarke,et al.  Ran GTPase: a master regulator of nuclear structure and function during the eukaryotic cell division cycle? , 2001, Trends in cell biology.

[32]  A. Giordano,et al.  RACK1 Interacts with E1A and Rescues E1A-induced Yeast Growth Inhibition and Mammalian Cell Apoptosis* , 2001, The Journal of Biological Chemistry.

[33]  G. Hortobagyi,et al.  Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[34]  M. Winey,et al.  The Mouse Mps1p-like Kinase Regulates Centrosome Duplication , 2001, Cell.

[35]  E. Cundari,et al.  p53 Displacement from Centrosomes and p53-mediated G1 Arrest following Transient Inhibition of the Mitotic Spindle* , 2001, The Journal of Biological Chemistry.

[36]  E. Hinchcliffe,et al.  "It takes two to tango": understanding how centrosome duplication is regulated throughout the cell cycle. , 2001, Genes & development.

[37]  J. Pines,et al.  Cyclin a Is Destroyed in Prometaphase and Can Delay Chromosome Alignment and Anaphase , 2001, The Journal of cell biology.

[38]  J. Nevins,et al.  The Rb/E2F pathway and cancer. , 2001, Human molecular genetics.

[39]  J. Decaprio,et al.  Cellular transformation by SV40 large T antigen: interaction with host proteins. , 2001, Seminars in cancer biology.

[40]  Jonathan D. Moore The Ran‐GTPase and cell‐cycle control , 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.

[41]  H. F. Horn,et al.  Nucleophosmin/B23 Is a Target of CDK2/Cyclin E in Centrosome Duplication , 2000, Cell.

[42]  D. Dean,et al.  Role of the LXCXE Binding Site in Rb Function , 2000, Molecular and Cellular Biology.

[43]  K. Münger,et al.  The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[44]  M. Kitagawa,et al.  Targeted disruption of Skp2 results in accumulation of cyclin E and p27Kip1, polyploidy and centrosome overduplication , 2000, The EMBO journal.

[45]  M. Carbone Simian virus 40 and human tumors: It is time to study mechanisms , 2000, Journal of cellular biochemistry.

[46]  T. Nishimoto Upstream and Downstream of Ran GTPase , 2000, Biological chemistry.

[47]  Miranda Thomas,et al.  The role of the E6-p53 interaction in the molecular pathogenesis of HPV , 1999, Oncogene.

[48]  M. Hung,et al.  E1A Sensitizes Cells to Tumor Necrosis Factor-induced Apoptosis through Inhibition of IκB Kinases and Nuclear Factor κB Activities* , 1999, The Journal of Biological Chemistry.

[49]  Jiri Bartek,et al.  Centrosome duplication in mammalian somatic cells requires E2F and Cdk2–Cyclin A , 1999, Nature Cell Biology.

[50]  E. Nishida,et al.  Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells , 1999, Current Biology.

[51]  W. Kaelin The emerging p53 gene family. , 1999, Journal of the National Cancer Institute.

[52]  Patrick E Carroll,et al.  Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression , 1999, Oncogene.

[53]  P. Jansen-Dürr,et al.  E2F target genes and cell‐cycle checkpoint control , 1999, BioEssays : news and reviews in molecular, cellular and developmental biology.

[54]  M. Hung,et al.  Adenovirus 5 E1A-mediated tumor suppression associated with E1A-mediated apoptosis in vivo , 1998, Oncogene.

[55]  L. Magnaghi-Jaulin,et al.  The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[56]  J. J. Chen,et al.  The papillomavirus E6 proteins. , 1998, Biochimica et biophysica acta.

[57]  T. Jacks,et al.  The retinoblastoma gene family: cousins with overlapping interests. , 1998, Trends in genetics : TIG.

[58]  L. Magnaghi-Jaulin,et al.  Retinoblastoma protein represses transcription by recruiting a histone deacetylase , 1998, Nature.

[59]  Tony Kouzarides,et al.  Retinoblastoma protein recruits histone deacetylase to repress transcription , 1998, Nature.

[60]  J. Goedert,et al.  Contamination of poliovirus vaccines with simian virus 40 (1955-1963) and subsequent cancer rates. , 1998, JAMA.

[61]  M. Strauss,et al.  The retinoblastoma protein: a master regulator of cell cycle, differentiation and apoptosis. , 1997, European journal of biochemistry.

[62]  R. Schlegel,et al.  Disregulation of mitotic checkpoints and regulatory proteins following acute expression of SV40 large T antigen in diploid human cells , 1997, Oncogene.

[63]  Bert Vogelstein,et al.  Gatekeepers and caretakers , 1997, Nature.

[64]  G. Stein,et al.  Cell cycle independent interaction of CDC2 with the centrosome, which is associated with the nuclear matrix-intermediate filament scaffold. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[65]  R. Long WHAT RESEARCH TRAINING OPPORTUNITIES ARE SPONSORED BY NIGMS AT THE NIH? HOW CAN I GET INFORMATION ABOUT THIS AND OTHER POSTDOCTORAL PROGRAMS AT THE NIH? , 1996, Pharmaceutical Research.

[66]  K. Kinzler,et al.  Lessons from Hereditary Colorectal Cancer , 1996, Cell.

[67]  A. Giordano,et al.  Retinoblastoma protein family in cell cycle and cancer: A review , 1996, Journal of cellular biochemistry.

[68]  P. Starostik,et al.  Transcriptional repression and growth suppression by the p107 pocket protein , 1996, Molecular and cellular biology.

[69]  P. Dirks,et al.  Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation. , 1996, Critical reviews in biochemistry and molecular biology.

[70]  S. Frisch Reversal of malignancy by the adenovirus E1a gene. , 1996, Mutation research.

[71]  E. White,et al.  Both viral (adenovirus E1B) and cellular (hsp 70, p53) components interact with centrosomes , 1994, Journal of cellular physiology.

[72]  A. Duncan,et al.  The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E. , 1993, Genes & development.

[73]  G. Hannon,et al.  Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. , 1993, Genes & development.

[74]  M. Ewen,et al.  Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein. , 1993, Genes & development.

[75]  E. White,et al.  Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. , 1993, Genes & development.

[76]  J. Minna,et al.  Interaction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteins , 1992, Journal of virology.

[77]  A. Berk,et al.  Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein , 1992, Nature.

[78]  Y. Qian,et al.  The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle , 1991, Cell.

[79]  S. Frisch Antioncogenic effect of adenovirus E1A in human tumor cells. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[80]  M. Ewen,et al.  Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein , 1991, Cell.

[81]  S. Bacchetti,et al.  Definition of adenovirus type 5 functions involved in the induction of chromosomal aberrations in human cells. , 1990, The Journal of general virology.

[82]  C. Meyers,et al.  The E7 proteins of the nononcogenic human papillomavirus type 6b (HPV-6b) and of the oncogenic HPV-16 differ in retinoblastoma protein binding and other properties , 1990, Journal of virology.

[83]  M. Dorée,et al.  p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase. , 1989, The EMBO journal.

[84]  Stephen H. Friend,et al.  Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product , 1988, Nature.

[85]  A. Braithwaite,et al.  Adenovirus-induced alterations of the cell growth cycle: a requirement for expression of E1A but not of E1B , 1983, Journal of virology.

[86]  G. Burton,et al.  Long-term follow-up of persons inadvertently inoculated with SV40 as neonates. , 1981, The New England journal of medicine.

[87]  A. Levine,et al.  Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells , 1979, Cell.

[88]  D. Lane,et al.  T antigen is bound to a host protein in SY40-transformed cells , 1979, Nature.

[89]  John Cairns,et al.  Mutation selection and the natural history of cancer , 1975, Nature.

[90]  Gary,et al.  Cell Cycle Inhibitors in Cancer Therapy , 2003, Cancer Drug Discovery and Development.

[91]  Laura Lentini,et al.  Functional inactivation of pRB results in aneuploid mammalian cells after release from a mitotic block. , 2002, Neoplasia.

[92]  B. Brinkley,et al.  Managing the centrosome numbers game: from chaos to stability in cancer cell division. , 2001, Trends in cell biology.

[93]  S. Frisch Tumor suppression activity of adenovirus E1a protein: anoikis and the epithelial phenotype. , 2001, Advances in cancer research.

[94]  W. Lingle,et al.  The role of the centrosome in the development of malignant tumors. , 2000, Current topics in developmental biology.

[95]  S. Reed,et al.  Multi-step control of spindle pole body duplication by cyclin-dependent kinase , 2000, Nature Cell Biology.

[96]  M. Kasten,et al.  The RB family of cell cycle regulatory factors. , 1998, Journal of cellular biochemistry. Supplement.

[97]  J. Nevins Adenovirus E1A: transcription regulation and alteration of cell growth control. , 1995, Current topics in microbiology and immunology.

[98]  D. Riley,et al.  The retinoblastoma protein: more than a tumor suppressor. , 1994, Annual review of cell biology.

[99]  J. Flint,et al.  Transcriptional and transforming activities of the adenovirus E1A proteins. , 1991, Advances in cancer research.