Bioterrorism: an overview

Abstract Bioterrorism has reached the forefront of the public imagination following recent events across the world. The disaster of 11 September 2001, followed by anthrax letters sent via the US postal system and now renewed tension over Iraq have all brought the possibility of bioterrorism closer. A number of biological agents could be used in a terrorist attack, including anthrax, plague, smallpox and botulinum toxin. The serious diseases that these agents produce have been brought under control in the developed world; however, a lack of protective immunity against such diseases could cause considerable morbidity and mortality if used in a terrorist attack. This essay provides a background to bioterrorism, discusses many of the current points of interest and gives an update to the economic consequences of such an attack.

[1]  J. Koplan CDC's Strategic Plan for Bioterrorism Preparedness and Response , 2001, Public health reports.

[2]  S. Clarke Nucleotide sequence-based typing of bacteria and the impact of automation. , 2002, BioEssays : news and reviews in molecular, cellular and developmental biology.

[3]  M. Osterholm How to vaccinate 30,000 people in three days: realities of outbreak management. , 2001, Public health reports.

[4]  J. D. Millar,et al.  Modeling potential responses to smallpox as a bioterrorist weapon. , 2001, Emerging infectious diseases.

[5]  A. Kemper,et al.  Expected adverse events in a mass smallpox vaccination campaign. , 2002, Effective clinical practice : ECP.

[6]  D. Michael Olive,et al.  Principles and Applications of Methods for DNA-Based Typing of Microbial Organisms , 1999, Journal of Clinical Microbiology.

[7]  M. Hamburg,et al.  Bioterrorism: responding to an emerging threat. , 2002, Trends in biotechnology.

[8]  K. Ruoff,et al.  Bioterrorism: Implications for the Clinical Microbiologist , 2001, Clinical Microbiology Reviews.

[9]  D E Swayne,et al.  Agroterrorism, biological crimes, and biowarfare targeting animal agriculture. The clinical, pathologic, diagnostic, and epidemiologic features of some important animal diseases. , 2001, Clinics in laboratory medicine.

[10]  R. Leggiadro The Threat of Biological Terrorism: A Public Health and Infection Control Reality , 2000, Infection Control & Hospital Epidemiology.

[11]  R. G. Darling,et al.  The history and threat of biological warfare and terrorism. , 2002, Emergency medicine clinics of North America.

[12]  B. Robinson-Dunn The microbiology laboratory's role in response to bioterrorism. , 2002, Archives of pathology & laboratory medicine.