Evidence for the presence of somatic mitochondrial DNA mutations in right atrial appendage tissues of coronary artery disease patients

[1]  Babajan Banaganapalli,et al.  Structural and functional characterization of pathogenic non- synonymous genetic mutations of human insulin-degrading enzyme by in silico methods. , 2014, CNS & neurological disorders drug targets.

[2]  Babajan Banaganapalli,et al.  Experimental and computational studies on newly synthesized resveratrol derivative: a new method for cancer chemoprevention and therapeutics? , 2013, Omics : a journal of integrative biology.

[3]  Yan Wang,et al.  Coronary heart disease is associated with a mutation in mitochondrial tRNA. , 2013, Human molecular genetics.

[4]  A. Orekhov,et al.  Mitochondrial mutations in atherosclerosis: new solutions in research and possible clinical applications. , 2013, Current pharmaceutical design.

[5]  J. McGeehan,et al.  Structural Analysis of Mitochondrial Mutations Reveals a Role for Bigenomic Protein Interactions in Human Disease , 2013, PloS one.

[6]  S. Caramel,et al.  The inherited real risk of coronary artery disease , 2013, European Journal of Clinical Nutrition.

[7]  Tariq Ahmad Masoodi,et al.  Functional genomics based prioritization of potential nsSNPs in EPHX1, GSTT1, GSTM1 and GSTP1 genes for breast cancer susceptibility studies. , 2012, Genomics.

[8]  Yuzhen Gao,et al.  The mitochondrial DNA 9-bp deletion polymorphism is a risk factor for hepatocellular carcinoma in the Chinese population. , 2012, Genetic testing and molecular biomarkers.

[9]  N. Shaik,et al.  Detection of somatic mutations and germline polymorphisms in mitochondrial DNA of uterine fibroids patients. , 2011, Genetic testing and molecular biomarkers.

[10]  Q. Hasan,et al.  Mitochondrial insertion-deletion polymorphism: role in disease pathology. , 2011, Genetic testing and molecular biomarkers.

[11]  M. Milone,et al.  Exercise intolerance due to cytochrome b mutation , 2010, Muscle & nerve.

[12]  Yang Zhang,et al.  I-TASSER: a unified platform for automated protein structure and function prediction , 2010, Nature Protocols.

[13]  G. Nemeth,et al.  The typical MERRF (A8344G) mutation of the mitochondrial DNA associated with depressive mood disorders , 2009, Journal of Neurology.

[14]  B. Brochet,et al.  Leber’s optic neuropathy associated with disseminated white matter disease: A case report and review , 2009, Clinical Neurology and Neurosurgery.

[15]  B. Robinson,et al.  Novel mitochondrial DNA mutations associated with myopathy, cardiomyopathy, renal failure, and deafness , 2006, American journal of medical genetics. Part A.

[16]  J. Cho,et al.  Chronic atrial fibrillation associated with somatic mitochondrial DNA mutations in human atrial tissue , 2006, Journal of Clinical Pathology.

[17]  P. Puddu,et al.  Molecular aspects of atherogenesis: new insights and unsolved questions. , 2005, Journal of biomedical science.

[18]  C. Meissner,et al.  Lack of age-related increase of mitochondrial DNA amount in brain, skeletal muscle and human heart , 2005, Mechanisms of Ageing and Development.

[19]  D. Wallace,et al.  A Case of Sporadic Infantile Histiocytoid Cardiomyopathy Caused by the A8344G (MERRF) Mitochondrial DNA Mutation , 2004, Pediatric Cardiology.

[20]  C. Florentz,et al.  Aminoacylation properties of pathology-related human mitochondrial tRNA(Lys) variants. , 2004, RNA.

[21]  Phillip Nagley,et al.  Precise determination of mitochondrial DNA copy number in human skeletal and cardiac muscle by a PCR-based assay: lack of change of copy number with age. , 2003, Nucleic acids research.

[22]  L. Wong,et al.  Comprehensive scanning of the entire mitochondrial genome for mutations. , 2002, Clinical chemistry.

[23]  G. D. De Meyer,et al.  Elevated Levels of Oxidative DNA Damage and DNA Repair Enzymes in Human Atherosclerotic Plaques , 2002, Circulation.

[24]  S. Ohta,et al.  A pathogenic point mutation reduces stability of mitochondrial mutant tRNA(Ile). , 2000, Nucleic acids research.

[25]  S. Dimauro,et al.  A Missense Mutation in the Mitochondrial Cytochrome b Gene in a Revisited Case with Histiocytoid Cardiomyopathy , 2000, Pediatric Research.

[26]  C. Florentz,et al.  Search for differences in post-transcriptional modification patterns of mitochondrial DNA-encoded wild-type and mutant human tRNALys and tRNALeu(UUR). , 1999, Nucleic acids research.

[27]  S. Dimauro,et al.  The mitochondrial DNA A8344G mutation in leigh syndrome revealed by analysis in paraffin‐embedded sections: Revisiting the past , 1998, Annals of neurology.

[28]  N. Howell,et al.  Association of the mitochondrial 8344 MERRF mutation with maternally inherited spinocerebellar degeneration and Leigh disease , 1996, Neurology.

[29]  I. Nelson,et al.  Congenital encephalomyopathy and adult-onset myopathy and diabetes mellitus: different phenotypic associations of a new heteroplasmic mtDNA tRNA glutamic acid mutation. , 1995, American journal of human genetics.

[30]  J. Enríquez,et al.  MtDNA mutation in MERRF syndrome causes defective aminoacylation of tRNALys and premature translation termination , 1995, Nature Genetics.

[31]  E. Schon,et al.  In vitro analysis of mutations causing myoclonus epilepsy with ragged-red fibers in the mitochondrial tRNA(Lys)gene: two genotypes produce similar phenotypes , 1995, Molecular and cellular biology.

[32]  S. Dimauro,et al.  Clinical features associated with the A → G transition at nucleotide 8344 of mtDNA (“MERRF mutation”) , 1993, Neurology.

[33]  D. Wallace,et al.  Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease. , 1992, Mutation research.

[34]  F. Sanger,et al.  Sequence and organization of the human mitochondrial genome , 1981, Nature.

[35]  D. Kelly,et al.  Mouse models of mitochondrial dysfunction and heart failure. , 2005, Journal of molecular and cellular cardiology.

[36]  C. Florentz,et al.  Mitochondrial tRNA 3' end metabolism and human disease. , 2004, Nucleic acids research.

[37]  M. Zeviani,et al.  Mitochondrial disorders. , 2004, Brain : a journal of neurology.

[38]  M. Andreassi.  Coronary atherosclerosis and somatic mutations: an overview of the contributive factors for oxidative DNA damage. , 2003, Mutation research.