A single glycan on IgE is indispensable for initiation of anaphylaxis

[1]  R. Maciuca,et al.  Targeting membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production , 2014, Science Translational Medicine.

[2]  André M Deelder,et al.  Site-specific N-glycosylation analysis of human immunoglobulin e. , 2014, Journal of proteome research.

[3]  M. Tsai,et al.  A beneficial role for immunoglobulin E in host defense against honeybee venom. , 2013, Immunity.

[4]  R. Medzhitov,et al.  Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity. , 2013, Immunity.

[5]  J. Ravetch,et al.  General mechanism for modulating immunoglobulin effector function , 2013, Proceedings of the National Academy of Sciences.

[6]  M. Muramatsu,et al.  IgG and IgE Collaboratively Accelerate Expulsion of Strongyloides venezuelensis in a Primary Infection , 2013, Infection and Immunity.

[7]  Stephen J Galli,et al.  IgE and mast cells in allergic disease , 2012, Nature Medicine.

[8]  H. Kuehn,et al.  Measuring Mast Cell Mediator Release , 2010, Current protocols in immunology.

[9]  Johannes Buchner,et al.  Structure of the murine unglycosylated IgG1 Fc fragment. , 2009, Journal of molecular biology.

[10]  Robert M. Anthony,et al.  Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc , 2008, Science.

[11]  Pauline M Rudd,et al.  The impact of glycosylation on the biological function and structure of human immunoglobulins. , 2007, Annual review of immunology.

[12]  James Hunt,et al.  Disulfide Linkage Controls the Affinity and Stoichiometry of IgE Fcϵ3–4 Binding to FcϵRI* , 2005, Journal of Biological Chemistry.

[13]  M. Flajnik.  Comparative analyses of immunoglobulin genes: surprises and portents , 2002, Nature Reviews Immunology.

[14]  S. Morrison.  Cloning, Expression, and Modification of Antibody V Regions , 2002, Current protocols in immunology.

[15]  David Fear,et al.  The biology of IGE and the basis of allergic disease. , 2001, Annual review of immunology.

[16]  J. Kinet,et al.  Structure of the Fc fragment of human IgE bound to its high-affinity receptor FcεRIα , 2000, Nature.

[17]  C. Magnusson,et al.  Characterisation of recombinant human IgE-Fc fragments expressed in baculovirus-infected insect cells. , 2000, Molecular immunology.

[18]  C. Magnusson,et al.  N-glycosylation influences epitope expression and receptor binding structures in human IgE. , 1999, Molecular immunology.

[19]  I. Sayers,et al.  Amino acid residues that influence Fc epsilon RI-mediated effector functions of human immunoglobulin E. , 1998, Biochemistry.

[20]  D. Dombrowicz,et al.  Anaphylaxis mediated through a humanized high affinity IgE receptor. , 1996, Journal of immunology.

[21]  J. Kochan,et al.  Role of glycosylation sites in the IgE Fc molecule. , 1995, International archives of allergy and immunology.

[22]  R. Owens,et al.  Secretion of recombinant human IgE-Fc by mammalian cells and biological activity of glycosylation site mutants. , 1995, Protein engineering.

[23]  D. Dombrowicz,et al.  Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor α chain gene , 1993, Cell.

[24]  A. Gilfillan,et al.  Purification and characterization of human recombinant IgE-Fc fragments that bind to the human high affinity IgE receptor. , 1993, The Journal of biological chemistry.

[25]  E. Padlan,et al.  The mast cell binding site on human immunoglobulin E , 1988, Nature.

[26]  H. Bennich,et al.  Structure‐Function Relationships in Human Immunoglobulin E , 1978, Immunological reviews.

[27]  S. Spector,et al.  Efficacy and Safety of Omalizumab in Patients with Chronic Idiopathic/Spontaneous Urticaria who Remain Symptomatic on H1 Antihistamines: A Randomized, Placebo-Controlled Study. , 2015, The Journal of investigative dermatology.