Interventional therapy of extracranial arteriovenous malformations of the head and neck—A systematic review

Objectives The primary aim of this study was to conduct a meta-analysis of the literature on interventional treatment for patients with extracranial AVM of the head and neck to identify a superior treatment. The secondary aim was to evaluate the methodological quality of associated articles published between 2000–2020. Methods The literature search was conducted on PubMed, Embase, the Cochrane Library, and scholar.google.com. Studies, meeting the acceptable reference standard underwent meta-analysis. All identified literature underwent methodological quality analysis. Results Of 1560 screened articles, 56 were included in the literature review. Appropriate diagnostic tests were reported in 98% of included articles. 13% of included articles did not specify the embolization agent. Outcome analysis varied throughout. 45% of the authors used radiographic imaging for follow-up. 77% specified the span of follow-up of their entire patient collective. Two articles met the inclusion criteria for meta-analysis. Curing rate of transarterial ethanol embolization for intraosseous AVM was 83% with a complication rate of 58%. Curing rate of ethanol combined with NBCA or Onyx in soft tissue AVM was 18% with a complication rate of 87%. Conclusion Our literature review revealed an absence of treatment or reporting standards for extracranial AVM of the head and neck. The meta-analysis is comprised of two articles and methodological quality is heterogeneous. We recommend implementing consistent reporting standards to facilitate comparability of studies and to provide robust data for the development of an evidence-based treatment strategy. Advances in knowledge Meta-analysis showed a favorable radiological outcome for intraosseous AVM when treated with intraarterial ethanol embolization. Our analysis demonstrated that the published data on extracranial AVMs of the head and neck is lacking in consistency and quality, prompting agreement for the need of standardized reporting on AVM treatments.

[1]  Ya-Chi Hsu,et al.  Giant congenital arteriovenous malformation over right upper limb causing heart failure. , 2020, Asian Journal of Surgery.

[2]  M. Vikkula,et al.  New and Emerging Targeted Therapies for Vascular Malformations , 2020, American Journal of Clinical Dermatology.

[3]  H. Haghighatkhah,et al.  Huge Arteriovenous Malformation of Upper Lip- A Case Report , 2020, Iranian journal of otorhinolaryngology.

[4]  Yun Zou,et al.  Clinical Course of Extracranial Arteriovenous Malformations. , 2019, The Journal of craniofacial surgery.

[5]  C. Prinsen,et al.  Outcome measurement instruments for peripheral vascular malformations and an assessment of the measurement properties: a systematic review , 2019, Quality of Life Research.

[6]  Radwan Ajlan,et al.  Ocular infarction following ethanol sclerotherapy of an arteriovenous malformation , 2019, American journal of ophthalmology case reports.

[7]  S. Hirakawa,et al.  Efficacy and safety of sirolimus treatment for intractable lymphatic anomalies: A study protocol for an open-label, single-arm, multicenter, prospective study (SILA) , 2019, Regenerative therapy.

[8]  R. Khosla,et al.  Management of Complex Arteriovenous Malformations Using a Novel Combination Therapeutic Algorithm , 2018, JAMA dermatology.

[9]  Tove Faber Frandsen,et al.  The impact of patient, intervention, comparison, outcome (PICO) as a search strategy tool on literature search quality: a systematic review , 2018, Journal of the Medical Library Association : JMLA.

[10]  G. Lanzino,et al.  Recurrent Brain Arteriovenous Malformations (AVMs): A Systematic Review. , 2018, World neurosurgery.

[11]  M. Tollefson,et al.  Vascular Malformations and Health-Related Quality of Life: A Systematic Review and Meta-analysis , 2018, JAMA dermatology.

[12]  M. Bendszus,et al.  Interdisciplinary treatment algorithm for facial high-flow arteriovenous malformations, and review of the literature. , 2018, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[13]  P. Cariati,et al.  Endovascular treatment of an intraosseous arteriovenous malformation of the mandible in a child. A case Report , 2018, Journal of clinical and experimental dentistry.

[14]  L. Su,et al.  Absolute Ethanol Embolization Combined with Surgical Resection of Scalp Arteriovenous Malformations: Interim Results. , 2017, Journal of vascular and interventional radiology : JVIR.

[15]  Thomas G. Walker,et al.  Proposal of a New Adverse Event Classification by the Society of Interventional Radiology Standards of Practice Committee. , 2017, Journal of vascular and interventional radiology : JVIR.

[16]  Yuhei Yamamoto,et al.  Transarterial Embolization and Transmucosal Sclerotherapy That Led to Successful Deliveries in a Patient With Symptomatic Arteriovenous Malformation of the Tongue. , 2017, The Journal of craniofacial surgery.

[17]  G. Duckwiler,et al.  Urticarial reaction following endovascular embolization of an orbital arteriovenous malformation (AVM) with n-butyl cyanoacrylate (nBCA) glue , 2017, Interventional Neuroradiology.

[18]  L. Su,et al.  Absolute Ethanol Embolisation of Mandibular Arteriovenous Malformations Following Direct Percutaneous Puncture and Release of Coils via a Microcatheter. , 2017, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[19]  K. terBrugge,et al.  Management of a large diffuse maxillofacial arteriovenous malformation previously treated with ligation of ipsilateral arterial supply. , 2017, Dento maxillo facial radiology.

[20]  J. López-Gutiérrez,et al.  Sirolimus in the Treatment of Vascular Anomalies , 2016, European Journal of Pediatric Surgery.

[21]  H. Lanfermann,et al.  Endovascular treatment of head and neck arteriovenous malformations: long-term angiographic and quality of life results , 2016, Journal of NeuroInterventional Surgery.

[22]  Wei‐liang Chen,et al.  Percutaneous sclerotherapy of arteriovenous malformations of the face using fibrin glue combined with OK-432 and bleomycin after embolisation. , 2016, The British journal of oral & maxillofacial surgery.

[23]  L. Su,et al.  Salvage treatment of hemorrhagic arteriovenous malformations in jaws. , 2015, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[24]  H. Byun,et al.  Long-term results of ethanol sclerotherapy with or without adjunctive surgery for head and neck arteriovenous malformations , 2015, Neuroradiology.

[25]  S. Pimpalwar.  Vascular Malformations: Approach by an Interventional Radiologist , 2014, Seminars in Plastic Surgery.

[26]  I. Baumgartner,et al.  Interventional treatment of arterio-venous malformations , 2014, Gefässchirurgie.

[27]  S. Dixit,et al.  Abnormal Vessel of the Ear Associated with Congenital Arteriovenous Malformation in the Postauricular Region , 2013, Indian Journal of Surgery.

[28]  R. Schmelzeisen,et al.  Use of the radial forearm artery for secondary embolization of an extensive life-threatening arteriovenous malformation of the mid-face and anterior skull base - a case report. , 2013, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[29]  J. Pekkola,et al.  Head and Neck Arteriovenous Malformations: Results of Ethanol Sclerotherapy , 2013, American Journal of Neuroradiology.

[30]  T. Ishiguchi,et al.  Ethanolamine oleate sclerotherapy combined with transarterial embolization using n-butyl cyanoacrylate for extracranial arteriovenous malformations , 2013, CardioVascular and Interventional Radiology.

[31]  H. Wong,et al.  Onyx embolization of a lingual arteriovenous malformation. , 2012, Asian journal of surgery.

[32]  S. Di Carlo,et al.  Treatment of facial vascular malformations with embolisation and surgical resection. , 2012, European review for medical and pharmacological sciences.

[33]  S. Di Carlo,et al.  Treatment of high-flow arteriovenous malformations (AVMs) of the head and neck with embolization and surgical resection. , 2011, Annali italiani di chirurgia.

[34]  I. Tawil,et al.  Acute Respiratory Distress Syndrome after Onyx Embolization of Arteriovenous Malformation , 2011, Critical care research and practice.

[35]  A. Atkinson,et al.  Arteriovenous Malformation in a Child with Extensive Involvement of the Mandible and Maxilla , 2010, Case Reports in Neurology.

[36]  G. Legiehn,et al.  A Step-by-Step Practical Approach to Imaging Diagnosis and Interventional Radiologic Therapy in Vascular Malformations , 2010, Seminars in interventional radiology.

[37]  Young Wook Kim,et al.  Extremity arteriovenous malformations involving the bone: therapeutic outcomes of ethanol embolotherapy. , 2010, Journal of vascular and interventional radiology : JVIR.

[38]  J. Mulliken,et al.  Extracranial arteriovenous malformations: natural progression and recurrence after treatment. , 2010, Plastic and reconstructive surgery.

[39]  J. Suen,et al.  Clinical course of arteriovenous malformations of the head and neck: A case series , 2010, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[40]  L. Su,et al.  Ethanol Embolization of Auricular Arteriovenous Malformations: Preliminary Results of 17 Cases , 2009, American Journal of Neuroradiology.

[41]  Z Y Zhang,et al.  Ethanol Embolization of Arteriovenous Malformations of the Mandible , 2009, American Journal of Neuroradiology.

[42]  K. Harii,et al.  Experience of sclerotherapy and embolosclerotherapy using ethanolamine oleate for vascular malformations of the head and neck , 2009, Scandinavian journal of plastic and reconstructive surgery and hand surgery.

[43]  D. Cooke,et al.  Embolization in the Head and Neck , 2008, Seminars in interventional radiology.

[44]  S. Maurya,et al.  Management strategy for facial arteriovenous malformations , 2008, Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India.

[45]  B. Thomas,et al.  Endovascular treatment of scalp cirsoid aneurysms. , 2008, Neurology India.

[46]  Dong Zhou,et al.  Embolization of a Bleeding Maxillary Arteriovenous Malformation via the Superficial Temporal Artery after External Carotid Artery Ligation , 2008, Korean journal of radiology.

[47]  A. Samsudin,et al.  Arteriovenous malformation of the mandible: a rare but life-threatening disease. , 2007, The Malaysian journal of medical sciences : MJMS.

[48]  E. Eskioglu,et al.  Onyx®: a unique neuroembolic agent , 2006, Expert review of medical devices.

[49]  J. Bilbao,et al.  Complications of Embolization , 2006, Seminars in interventional radiology.

[50]  Jianguang Wang,et al.  Comprehensive treatment of arteriovenous malformations in the oral and maxillofacial region. , 2005, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[51]  R. Zuker,et al.  Congenital Arteriovenous Malformations: A Follow-Up of Treatment , 2005, The Canadian journal of plastic surgery = Journal canadien de chirurgie plastique.

[52]  T. Pradhan,et al.  Bleomycin sclerotherapy in congenital lymphatic and vascular malformations of head and neck. , 2005, International journal of pediatric otorhinolaryngology.

[53]  Y. Do,et al.  Serum Ethanol Levels after Alcohol Sclerotherapy of Arteriovenous Malformations , 2004, Journal of Korean medical science.

[54]  B. Lee,et al.  Advanced management of venous malformation with ethanol sclerotherapy: mid-term results. , 2003, Journal of vascular surgery.

[55]  J. Hand,et al.  Vascular birthmarks of infancy: resolving nosologic confusion. , 2002, American journal of medical genetics.

[56]  F. Hammer,et al.  Ethanol sclerotherapy of venous malformations: evaluation of systemic ethanol contamination. , 2001, Journal of vascular and interventional radiology : JVIR.

[57]  D. Zurakowski,et al.  Serum ethanol levels in children and adults after ethanol embolization or sclerotherapy for vascular anomalies. , 2000, Radiology.

[58]  C. Kerber,et al.  Liquid acrylic adhesive agents in interventional neuroradiology. , 2000, Neurosurgery clinics of North America.

[59]  W. Yih,et al.  Central hemangioma of the jaws. , 1989, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[60]  J. Glowacki,et al.  Hemangiomas and Vascular Malformations in Infants and Children: A Classification Based on Endothelial Characteristics , 1982, Plastic and reconstructive surgery.