Uptake and efflux of chloroquine by chloroquine-resistant Plasmodium falciparum clones recently isolated in Africa.

[1]  A. Cowman,et al.  The mode of action and the mechanism of resistance to antimalarial drugs. , 1994, Acta tropica.

[2]  J. Carlton,et al.  Drug response and genetic characterization of Plasmodium falciparum clones recently isolated from a Sudanese village. , 1993, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[3]  S. Ward,et al.  Rapid chloroquine efflux phenotype in both chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum. A correlation of chloroquine sensitivity with energy-dependent drug accumulation. , 1992, Biochemical pharmacology.

[4]  H. Ginsburg,et al.  Quinoline-containing antimalarials--mode of action, drug resistance and its reversal. An update with unresolved puzzles. , 1992, Biochemical pharmacology.

[5]  A. Cerami,et al.  Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites , 1992, Nature.

[6]  D. Cutler,et al.  Simulation of kinetic data on the influx and efflux of chloroquine by erythrocytes infected with Plasmodium falciparum. Evidence for a drug-importer in chloroquine-sensitive strains. , 1991, Biochemical pharmacology.

[7]  R. Bayoumi,et al.  Genetic diversity of Plasmodium falciparum in a village in eastern Sudan. 2. Drug resistance, molecular karyotypes and the mdr1 genotype of recent isolates. , 1991, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[8]  R. Bayoumi,et al.  Genetic diversity of Plasmodium falciparum in a village in eastern Sudan. 1. Diversity of enzymes, 2D-PAGE proteins and antigens. , 1991, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[9]  H. Ginsburg,et al.  Kinetic modelling of chloroquine uptake by malaria-infected erythrocytes. Assessment of the factors that may determine drug resistance. , 1991, Biochemical pharmacology.

[10]  H. Ginsburg,et al.  Kinetic modelling of the response of Plasmodium falciparum to chloroquine and its experimental testing in vitro. Implications for mechanism of action of and resistance to the drug. , 1990, Biochemical pharmacology.

[11]  I. Gluzman,et al.  A rapid in vitro test for chloroquine-resistant Plasmodium falciparum. , 1990, The American journal of tropical medicine and hygiene.

[12]  S. Meshnick,et al.  Chloroquine as intercalator: a hypothesis revived. , 1990, Parasitology today.

[13]  R. Bayoumi,et al.  Chloroquine-resistant Plasmodium falciparum in eastern Sudan. , 1989, Acta tropica.

[14]  D. Warhurst.  Mechanism of chloroquine resistance in malaria. , 1988, Parasitology today.

[15]  H. Ginsburg.  Effect of calcium antagonists on malaria susceptibility to chloroquine. , 1988, Parasitology today.

[16]  I. Gluzman,et al.  Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance. , 1987, Science.

[17]  H. Ginsburg,et al.  Uptake of [3H]chloroquine by drug-sensitive and -resistant strains of the human malaria parasite Plasmodium falciparum. , 1986, Biochemical pharmacology.

[18]  H. Ginsburg,et al.  Susceptibility of human malaria parasites to chloroquine is pH dependent. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[19]  J. Le bras,et al.  Chloroquine uptake by Plasmodium falciparum-infected human erythrocytes during in vitro culture and its relationship to chloroquine resistance , 1985, Antimicrobial Agents and Chemotherapy.

[20]  C. D. Fitch,et al.  Mode of action of antimalarial drugs. , 1983, Ciba Foundation symposium.

[21]  W. Trager,et al.  Plasmodium falciparum in culture: use of outdated erthrocytes and description of the candle jar method. , 1977, The Journal of parasitology.

[22]  D. Warhurst,et al.  Lysosomes, pH and the Anti-malarial Action of Chloroquine , 1972, Nature.

[23]  C. D. Fitch.  Plasmodium falciparum in Owl Monkeys: Drug Resistance and Chloroquine Binding Capacity , 1970, Science.