White Matter Fiber Tracts Based On Diffusion Tensor Imaging

The recently developed magnetic resonance imaging technique of diffusion tensor imaging (DTI) has a widespread application on investigating the cerebral white matter architecture. When referred to fiber tracking, as the typical application of DTI, one of the most intuitive ways to reconstruct fiber trajectory is streamline tracking, (STT). Regarding the problems from noise and discrete tensor field in traditional STT algorithm, we introduce the concept of adjacent and previous voxels as well as the break point during fiber tracking. To evaluate the validity of our improved algorithm, we firstly applied it on the simulated data and meanwhile obtained some available values in our approach. Then the traditional STT and improved algorithm were both applied to DTI data to reconstruct the fiber trajectory. The results showed our improved method did follow the actual fiber more precisely. Future improvements were also discussed in the end of the paper.

[1]  C R Tench,et al.  Improved white matter fiber tracking using stochastic labeling , 2002, Magnetic resonance in medicine.

[2]  L. M. Auer,et al.  Fiber Tracking from DTI Using Linear State Space Models: Detectability of the Pyramidal Tract , 2002, NeuroImage.

[3]  P. Basser,et al.  In vivo fiber tractography using DT‐MRI data , 2000, Magnetic resonance in medicine.

[4]  P. V. van Zijl,et al.  Three‐dimensional tracking of axonal projections in the brain by magnetic resonance imaging , 1999, Annals of neurology.

[5]  Denis Le Bihan,et al.  Looking into the functional architecture of the brain with diffusion MRI , 2003, Nature Reviews Neuroscience.

[6]  M. Raichle,et al.  Tracking neuronal fiber pathways in the living human brain. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[7]  D. Rye Tracking neural pathways with MRI , 1999, Trends in Neurosciences.

[8]  A. Alexander,et al.  Diffusion tensor imaging of cerebral white matter: a pictorial review of physics, fiber tract anatomy, and tumor imaging patterns. , 2004, AJNR. American journal of neuroradiology.

[9]  A. Alexander,et al.  White matter tractography using diffusion tensor deflection , 2003, Human brain mapping.

[10]  P. Basser,et al.  A continuous tensor field approximation of discrete DT-MRI data for extracting microstructural and architectural features of tissue. , 2002, Journal of magnetic resonance.

[11]  Richard Frayne,et al.  Visualizing three‐dimensional flow with simulated streamlines and three‐dimensional phase‐contrast MR imaging , 1992, Journal of magnetic resonance imaging : JMRI.

[12]  D. Parker,et al.  Analysis of partial volume effects in diffusion‐tensor MRI , 2001, Magnetic resonance in medicine.

[13]  S. Wakana,et al.  Fiber tract-based atlas of human white matter anatomy. , 2004, Radiology.