Pulmonary hyperpolarized noble gas MRI: recent advances and perspectives in clinical application.

[1]  K. Riekert,et al.  Update on Key Emerging Challenges in Cystic Fibrosis , 2014, Medical Principles and Practice.

[2]  I. Ball,et al.  Pulmonary ultrashort echo time 19F MR imaging with inhaled fluorinated gas mixtures in healthy volunteers: feasibility. , 2013, Radiology.

[3]  W. M. Foster,et al.  Perfluoropropane gas as a magnetic resonance lung imaging contrast agent in humans. , 2013, Chest.

[4]  R. Rizi,et al.  Regional alveolar partial pressure of oxygen measurement with parallel accelerated hyperpolarized gas MRI. , 2013, Academic radiology.

[5]  Stanley J Kruger,et al.  Exercise-induced bronchoconstriction: reproducibility of hyperpolarized 3He MR imaging. , 2013, Radiology.

[6]  R. Castillo,et al.  Hyperpolarized (3)He magnetic resonance imaging: comparison with four-dimensional x-ray computed tomography imaging in lung cancer. , 2012, Academic radiology.

[7]  M. Puderbach,et al.  MRI of the lung (1/3): methods , 2012, Insights into Imaging.

[8]  S. Karpuk,et al.  Recycling of 3He from lung magnetic resonance imaging , 2012, Magnetic Resonance in Medicine.

[9]  M. Puderbach,et al.  MRI of the lung (3/3)—current applications and future perspectives , 2012, Insights into Imaging.

[10]  K. Sheng,et al.  Helical tomotherapy planning for lung cancer based on ventilation magnetic resonance imaging. , 2011, Medical dosimetry : official journal of the American Association of Medical Dosimetrists.

[11]  Titus Lanz,et al.  A flexible 32‐channel receive array combined with a homogeneous transmit coil for human lung imaging with hyperpolarized 3He at 1.5 T , 2011, Magnetic resonance in medicine.

[12]  J. P. Roche,et al.  Using hyperpolarized 3He MRI to evaluate treatment efficacy in cystic fibrosis patients , 2011, Journal of magnetic resonance imaging : JMRI.

[13]  G. Parraga,et al.  Quantitative evaluation of hyperpolarized helium-3 magnetic resonance imaging of lung function variability in cystic fibrosis. , 2011, Academic radiology.

[14]  J. Repine,et al.  Effects of pulmonary inhalation on hyperpolarized krypton-83 magnetic resonance T1 relaxation , 2011, Physics in medicine and biology.

[15]  G. Parraga,et al.  Hyperpolarized ³He magnetic resonance imaging: preliminary evaluation of phenotyping potential in chronic obstructive pulmonary disease. , 2011, European journal of radiology.

[16]  Isabel Dregely,et al.  Hyperpolarized Xenon‐129 gas‐exchange imaging of lung microstructure: First case studies in subjects with obstructive lung disease , 2011, Journal of magnetic resonance imaging : JMRI.

[17]  Jan Wolber,et al.  Diffusion‐weighted hyperpolarized 129Xe MRI in healthy volunteers and subjects with chronic obstructive pulmonary disease , 2011, Magnetic resonance in medicine.

[18]  R. Pierce,et al.  Imaging alveolar-duct geometry during expiration via ³He lung morphometry. , 2011, Journal of applied physiology.

[19]  A. Luna,et al.  Diffusion-weighted imaging of the chest. , 2011, Magnetic resonance imaging clinics of North America.

[20]  P. Zygmanski,et al.  Can Hyperpolarized Helium MRI add to radiation planning and follow‐up in lung cancer? , 2011, Journal of applied clinical medical physics.

[21]  M. Mehta,et al.  On the use of hyperpolarized helium MRI for conformal avoidance lung radiotherapy. , 2010, Medical dosimetry : official journal of the American Association of Medical Dosimetrists.

[22]  J. Butler,et al.  Inhalation heterogeneity from subresidual volumes in elite divers. , 2010, Journal of applied physiology.

[23]  Grace Parraga,et al.  Imaging of lung function using hyperpolarized helium‐3 magnetic resonance imaging: Review of current and emerging translational methods and applications , 2010, Journal of magnetic resonance imaging : JMRI.

[24]  Eduard E de Lange,et al.  Demonstration of the heterogeneous distribution of asthma in the lungs using CT and hyperpolarized helium‐3 MRI , 2010, Journal of magnetic resonance imaging : JMRI.

[25]  G. Miller,et al.  Simultaneous magnetic resonance imaging of ventilation distribution and gas uptake in the human lung using hyperpolarized xenon-129 , 2010, Proceedings of the National Academy of Sciences.

[26]  Edwin J R van Beek,et al.  Detection of radiation-induced lung injury in non-small cell lung cancer patients using hyperpolarized helium-3 magnetic resonance imaging. , 2010, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[27]  E. L. Wright,et al.  Xenon as an anesthetic agent. , 2010, AANA journal.

[28]  T. Pilgram,et al.  Emphysema Quantification in Inflation-Fixed Lungs Using Low-Dose Computed Tomography and 3He Magnetic Resonance Imaging , 2010, Journal of computer assisted tomography.

[29]  Jan Wolber,et al.  Hyperpolarized 129Xe MR Imaging of Alveolar Gas Uptake in Humans , 2010, PloS one.

[30]  S. Choy,et al.  Hyperpolarized (3)He magnetic resonance imaging-derived pulmonary pressure-volume curves. , 2010, Journal of applied physiology.

[31]  Miranda Kirby,et al.  Chronic obstructive pulmonary disease: longitudinal hyperpolarized (3)He MR imaging. , 2010, Radiology.

[32]  John P Mugler,et al.  Feature analysis of hyperpolarized helium‐3 pulmonary MRI: A study of asthmatics versus nonasthmatics , 2010, Magnetic resonance in medicine.

[33]  G Wilson Miller,et al.  Pulmonary kinematics from tagged hyperpolarized helium‐3 MRI , 2010, Journal of magnetic resonance imaging : JMRI.

[34]  P. Reix,et al.  Hyperpolarized 3He MR for sensitive imaging of ventilation function and treatment efficiency in young cystic fibrosis patients with normal lung function. , 2010, Radiology.

[35]  G. Miller,et al.  A short‐breath‐hold technique for lung pO2 mapping with 3He MRI , 2010, Magnetic Resonance in Medicine.

[36]  Rebecca S Lewis,et al.  Projected cancer risks from computed tomographic scans performed in the United States in 2007. , 2009, Archives of internal medicine.

[37]  G. Parraga,et al.  Detection of longitudinal lung structural and functional changes after diagnosis of radiation-induced lung injury using hyperpolarized 3He magnetic resonance imaging. , 2009, Medical physics.

[38]  E. D. de Lange,et al.  Imaging of the distal airways. , 2009, The Journal of allergy and clinical immunology.

[39]  E. V. van Beek,et al.  Assessment of hyperpolarized 3He lung MRI for regional evaluation of interventional therapy: A pilot study in pediatric cystic fibrosis , 2009, Journal of Magnetic Resonance Imaging.

[40]  A. Dirksen,et al.  Progression of emphysema evaluated by MRI using hyperpolarized 3he (hp 3he) measurements in patients with alpha-1-antitrypsin (a1at) deficiency compared with CT and lung function tests , 2009, Acta radiologica.

[41]  G Wilson Miller,et al.  Dynamic MRI of grid-tagged hyperpolarized helium-3 for the assessment of lung motion during breathing. , 2009, International journal of radiation oncology, biology, physics.

[42]  R. Rizi,et al.  Quantitative assessment of lung using hyperpolarized magnetic resonance imaging. , 2009, Proceedings of the American Thoracic Society.

[43]  H. Kauczor,et al.  Imaging of pulmonary pathologies: focus on magnetic resonance imaging. , 2009, Proceedings of the American Thoracic Society.

[44]  P. Leander,et al.  Validity of apparent diffusion coefficient hyperpolarized 3He-MRI using MSCT and pulmonary function tests as references. , 2009, European journal of radiology.

[45]  M. Clemence,et al.  Susceptibility effects in hyperpolarized 3He lung MRI at 1.5T and 3T , 2009, Journal of magnetic resonance imaging : JMRI.

[46]  S. Patz,et al.  Hyperpolarized gas MR Imaging of the lung: current status as a research tool. , 2009, Journal of thoracic imaging.

[47]  J. Butler,et al.  Science to practice: how do we interpret the transfer of hyperpolarized 129Xe from blood into alveolar gas? , 2009, Radiology.

[48]  L. Hedlund,et al.  Pulmonary perfusion and xenon gas exchange in rats: MR imaging with intravenous injection of hyperpolarized 129Xe. , 2009, Radiology.

[49]  T. Tuthill,et al.  Progression of emphysema in a 12-month hyperpolarized 3He-MRI study: lacunarity analysis provided a more sensitive measure than standard ADC analysis. , 2009, Academic radiology.

[50]  R. Rizi,et al.  Simultaneous measurement of pulmonary partial pressure of oxygen and apparent diffusion coefficient by hyperpolarized 3He MRI , 2009, Magnetic resonance in medicine.

[51]  Edward Y Lee,et al.  Hyperpolarized 3He MR Imaging of the Lung: Normal Range of Ventilation Defects and PFT Correlation in Young Adults , 2009, Journal of thoracic imaging.

[52]  Kenneth Lutchen,et al.  The difference in ventilation heterogeneity between asthmatic and healthy subjects quantified using hyperpolarized 3He MRI. , 2009, Journal of applied physiology.

[53]  Yanping Sun,et al.  Probing airway conditions governing ventilation defects in asthma via hyperpolarized MRI image functional modeling. , 2009, Journal of applied physiology.

[54]  J. Mugler,et al.  Changes in regional airflow obstruction over time in the lungs of patients with asthma: evaluation with 3He MR imaging. , 2009, Radiology.

[55]  Grace Parraga,et al.  Hyperpolarized 3He magnetic resonance imaging of chronic obstructive pulmonary disease: reproducibility at 3.0 tesla. , 2008, Academic radiology.

[56]  G. Miller,et al.  Assessment of the lung microstructure in patients with asthma using hyperpolarized 3He diffusion MRI at two time scales: Comparison with healthy subjects and patients with COPD , 2008, Journal of Magnetic Resonance Imaging.

[57]  G. Washko,et al.  Investigation of hyperpolarized 3He magnetic resonance imaging utility in examining human airway diameter behavior in asthma through comparison with high-resolution computed tomography. , 2008, Academic radiology.

[58]  W. Busse,et al.  Evaluation of structure-function relationships in asthma using multidetector CT and hyperpolarized He-3 MRI. , 2008, Academic radiology.

[59]  Hiroto Hatabu,et al.  Human pulmonary imaging and spectroscopy with hyperpolarized 129Xe at 0.2T. , 2008, Academic radiology.

[60]  G Wilson Miller,et al.  Helium-3 diffusion MR imaging of the human lung over multiple time scales. , 2008, Academic radiology.

[61]  Grace Parraga,et al.  Hyperpolarized 3He magnetic resonance imaging of ventilation defects in healthy elderly volunteers: initial findings at 3.0 Tesla. , 2008, Academic radiology.

[62]  Per Wollmer,et al.  Hyperpolarized 3He apparent diffusion coefficient MRI of the lung: Reproducibility and volume dependency in healthy volunteers and patients with emphysema , 2008, Journal of magnetic resonance imaging : JMRI.

[63]  G. Miller,et al.  Extending the range of diffusion times for regional measurement of the 3He ADC in human lungs , 2008, Magnetic resonance in medicine.

[64]  J. Repine,et al.  Detection of tobacco smoke deposition by hyperpolarized krypton-83 MRI. , 2008, Magnetic resonance imaging.

[65]  Hiroto Hatabu,et al.  Hyperpolarized (129)Xe MRI: a viable functional lung imaging modality? , 2007, European journal of radiology.

[66]  H. Kauczor,et al.  Oxygen-sensitive 3He-MRI in bronchiolitis obliterans after lung transplantation , 2007, European Radiology.

[67]  Jiang Du,et al.  Imaging of lung ventilation and respiratory dynamics in a single ventilation cycle using hyperpolarized He‐3 MRI , 2007, Journal of magnetic resonance imaging : JMRI.

[68]  T A Altes,et al.  MR grid‐tagging using hyperpolarized helium‐3 for regional quantitative assessment of pulmonary biomechanics and ventilation , 2007, Magnetic resonance in medicine.

[69]  G Wilson Miller,et al.  Direct measurement of lung motion using hyperpolarized helium-3 MR tagging. , 2007, International journal of radiation oncology, biology, physics.

[70]  H. Kauczor,et al.  Clinical aspects of the apparent diffusion coefficient in 3He MRI: Results in healthy volunteers and patients after lung transplantation , 2007, Journal of magnetic resonance imaging : JMRI.

[71]  Aaron Fenster,et al.  Hyperpolarized 3He Ventilation Defects and Apparent Diffusion Coefficients in Chronic Obstructive Pulmonary Disease: Preliminary Results at 3.0 Tesla , 2007, Investigative radiology.

[72]  John P Mugler,et al.  The variability of regional airflow obstruction within the lungs of patients with asthma: assessment with hyperpolarized helium-3 magnetic resonance imaging. , 2007, The Journal of allergy and clinical immunology.

[73]  Jim M. Wild,et al.  Assessment of lung disease in children with cystic fibrosis using hyperpolarized 3-Helium MRI: comparison with Shwachman score, Chrispin-Norman score and spirometry , 2007, European Radiology.

[74]  J. Wooten,et al.  Hyperpolarized 83Kr and 129Xe NMR relaxation measurements of hydrated surfaces: implications for materials science and pulmonary diagnostics. , 2007, Journal of the American Chemical Society.

[75]  Gunnar Sparr,et al.  A fast and highly automated approach to myocardial motion analysis using phase contrast magnetic resonance imaging , 2006, Journal of magnetic resonance imaging : JMRI.

[76]  C. Heussel,et al.  Subsecond fluorine‐19 MRI of the lung , 2006, Magnetic resonance in medicine.

[77]  E. L. McKinstry,et al.  Distal airways in humans: dynamic hyperpolarized 3He MR imaging--feasibility. , 2003, Radiology.

[78]  H. Kauczor,et al.  Analysis of intrapulmonary O(2) concentration by MR imaging of inhaled hyperpolarized helium-3. , 1999, Journal of applied physiology.

[79]  E E de Lange,et al.  MR imaging and spectroscopy using hyperpolarized 129Xe gas: Preliminary human results , 1997, Magnetic resonance in medicine.

[80]  A Potthast,et al.  Normal and abnormal pulmonary ventilation: visualization at hyperpolarized He-3 MR imaging. , 1996, Radiology.

[81]  H C Charles,et al.  Human lung air spaces: potential for MR imaging with hyperpolarized He-3. , 1996, Radiology.

[82]  P Bachert,et al.  Nuclear magnetic resonance imaging with hyperpolarised helium-3 , 1996, The Lancet.

[83]  W. Happer,et al.  Biological magnetic resonance imaging using laser-polarized 129Xe , 1994, Nature.

[84]  D. Gur,et al.  Adverse reactions to xenon-enhanced CT cerebral blood flow determination. , 1987, Radiology.

[85]  D. Gur,et al.  Side effects of xenon inhalation. , 1981, Journal of computer assisted tomography.

[86]  M. Dunnill THE PATHOLOGY OF ASTHMA, WITH SPECIAL REFERENCE TO CHANGES IN THE BRONCHIAL MUCOSA , 1960, Journal of clinical pathology.

[87]  A. Owrangi,et al.  Quantitative (1)H and hyperpolarized (3)He magnetic resonance imaging: comparison in chronic obstructive pulmonary disease and healthy never-smokers. , 2014, European journal of radiology.

[88]  Jan Wolber,et al.  Chronic obstructive pulmonary disease: safety and tolerability of hyperpolarized 129Xe MR imaging in healthy volunteers and patients. , 2012, Radiology.

[89]  S. Hurd,et al.  Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. , 2007, American journal of respiratory and critical care medicine.

[90]  M. Welsh,et al.  Chloride and potassium channels in cystic fibrosis airway epithelia , 1986, Nature.