Structural requirements of phenol derivatives for direct activation of chloride currents via GABA(A) receptors.

[1]  T. Mashimo,et al.  The α and γ subunit-dependent effects of local anesthetics on recombinant GABAA receptors , 2000 .

[2]  R. Dengler,et al.  Voltage‐dependent blockade of normal and mutant muscle sodium channels by benzylalcohol , 2000, British journal of pharmacology.

[3]  H. Adelsberger,et al.  Desensitization characteristics of rat recombinant GABAA receptors consisting of α1β2γ2S and α1β2 subunits expressed in HEK293 cells , 2000, Neuroscience Letters.

[4]  R. Dengler,et al.  Voltage‐dependent block of normal and mutant muscle sodium channels by 4‐Chloro‐m‐Cresol , 1999, British journal of pharmacology.

[5]  L. Mather,et al.  Stereoselective interaction of thiopentone enantiomers with the GABAA receptor , 1999, British journal of pharmacology.

[6]  B. Rehberg,et al.  Suppression of central nervous system sodium channels by propofol. , 1999, Anesthesiology.

[7]  F. Holsboer,et al.  Bidirectional effects of the neuroactive steroid tetrahydrodeoxycorticosterone on GABA‐activated Cl− currents in cultured rat hypothalamic neurons , 1999, British journal of pharmacology.

[8]  G. Biggio,et al.  Characterization of the electrophysiological and pharmacological effects of 4‐iodo‐2,6‐diisopropylphenol, a propofol analogue devoid of sedative‐anaesthetic properties , 1999, British journal of pharmacology.

[9]  R. Pearce,et al.  Dual actions of volatile anesthetics on GABA(A) IPSCs: dissociation of blocking and prolonging effects. , 1998, Anesthesiology.

[10]  K. Krampfl,et al.  Molecular modulation of recombinant rat α 1 β 2 γ 2 GABAA receptor channels by diazepam , 1998, Neuroscience Letters.

[11]  D. Saint.  The effects of propofol on macroscopic and single channel sodium currents in rat ventricular myocytes , 1998, British journal of pharmacology.

[12]  D. Saint,et al.  PROPOFOL BLOCK OF CARDIAC SODIUM CURRENTS IN RAT ISOLATED MYOCARDIAL CELLS IS INCREASED AT DEPOLARIZED RESTING POTENTIALS , 1998, Clinical and experimental pharmacology & physiology.

[13]  G. Biggio,et al.  Propofol analogues. Synthesis, relationships between structure and affinity at GABAA receptor in rat brain, and differential electrophysiological profile at recombinant human GABAA receptors. , 1998, Journal of medicinal chemistry.

[14]  J. McArdle,et al.  Cocaine depresses GABAA current of hippocampal neurons , 1997, Brain Research.

[15]  J. Elliott,et al.  Voltage-dependent inhibition of RCK1 K+ channels by phenol, p-cresol, and benzyl alcohol. , 1997, Molecular pharmacology.

[16]  E. Kochs,et al.  Isoflurane and Sevoflurane Interact with the Nicotinic Acetylcholine Receptor Channels in Micromolar Cconcentrations , 1997, Anesthesiology.

[17]  S. Enna.  The GABA receptors , 1997 .

[18]  M. Pistis,et al.  The Interaction of Intravenous Anesthetic Agents with Native and Recombinant GABAA Receptors , 1997 .

[19]  J. A. Peters,et al.  Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed in Xenopus laevis oocytes , 1996, British journal of pharmacology.

[20]  H. Parnas,et al.  Open Channel Block by Physostigmine and Procaine in Embryonic‐like Nicotinic Receptors of Mouse Muscle , 1996, The European journal of neuroscience.

[21]  R. Mckernan,et al.  Which GABAA-receptor subtypes really occur in the brain? , 1996, Trends in Neurosciences.

[22]  M. Hara,et al.  Local anesthetics reduce the inhibitory neurotransmitter-induced current in dissociated hippocampal neurons of the rat. , 1995, European journal of pharmacology.

[23]  G. Biggio,et al.  Actions of the general anesthetic propofol on recombinant human GABAA receptors: influence of receptor subunits. , 1995, The Journal of pharmacology and experimental therapeutics.

[24]  R. Harris,et al.  Novel properties of homomeric beta 1 gamma-aminobutyric acid type A receptors: actions of the anesthetics propofol and pentobarbital. , 1995, Molecular pharmacology.

[25]  P. Århem,et al.  Mechanisms of propofol action on ion currents in the myelinated axon of Xenopus laevis. , 1992, European journal of pharmacology.

[26]  N. Harrison,et al.  Enhancement of gamma‐aminobutyric acid‐activated Cl‐ currents in cultured rat hippocampal neurones by three volatile anaesthetics. , 1992, The Journal of physiology.

[27]  T. Hales,et al.  The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones , 1991, British journal of pharmacology.

[28]  P. W. Codding,et al.  Spatial requirements of the Na channel binding site for class I antiarrhythmics as derived from the crystal structures of 4-substituted 2,6-bis(1-pyrrolidinylmethyl)phenols. , 1991, Journal of medicinal chemistry.

[29]  Hondeghem Lm,et al.  Quantitative structure activity studies of antiarrhythmic properties in a series of lidocaine and procainamide derivatives. , 1988, The Journal of pharmacology and experimental therapeutics.

[30]  H. Hatt,et al.  Liquid filament switch for ultra-fast exchanges of solutions at excised patches of synaptic membrane of crayfish muscle , 1987, Neuroscience Letters.

[31]  B. Robertson,et al.  Prolongation of inhibitory postsynaptic currents by pentobarbitone, halothane and ketamine in CA1 pyramidal cells in rat hippocampus , 1985, British journal of pharmacology.

[32]  R James,et al.  Synthesis, biological evaluation, and preliminary structure-activity considerations of a series of alkylphenols as intravenous anesthetic agents. , 1980, Journal of medicinal chemistry.