Rye bran and soy protein delay growth and increase apoptosis of human LNCaP prostate adenocarcinoma in nude mice

In this study, we investigated whether dietary intervention could inhibit tumor growth of an androgen‐sensitive human prostatic cancer.

[1]  T. Hurley,et al.  Nutritional and socioeconomic factors in relation to prostate cancer mortality: a cross-national study. , 1998, Journal of the National Cancer Institute.

[2]  G. Hallmans,et al.  Inhibitory effects of soy and rye diets on the development of Dunning R3327 prostate adenocarcinoma in rats , 1998, The Prostate.

[3]  S. Ripatti,et al.  Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: incidence and mortality in a controlled trial. , 1998, Journal of the National Cancer Institute.

[4]  F. Stephens,et al.  Phytoestrogens and prostate cancer: possible preventive role , 1997, The Medical journal of Australia.

[5]  H. Adlercreutz,et al.  Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis. , 1997, Cancer research.

[6]  L. Vatten,et al.  Prediagnostic level of fatty acids in serum phospholipids: Ω‐3 and Ω‐6 fatty acids and the risk of prostate cancer , 1997 .

[7]  W. Mazur,et al.  Phyto-oestrogens and Western diseases. , 1997, Annals of medicine.

[8]  G. Hallmans,et al.  Soy and rye diets inhibit the development of Dunning R3327 prostatic adenocarcinoma in rats. , 1997, Cancer letters.

[9]  H. Adami,et al.  Body size and prostate cancer: a 20-year follow-up study among 135006 Swedish construction workers. , 1997, Journal of the National Cancer Institute.

[10]  E. Kyle,et al.  Genistein-induced apoptosis of prostate cancer cells is preceded by a specific decrease in focal adhesion kinase activity. , 1997, Molecular pharmacology.

[11]  K. Lorenz,et al.  ANTIOXIDANT POTENTIAL OF 5-n-PENTADECYLRESORCINOL , 1996 .

[12]  J. Folkman,et al.  Angiostatin induces and sustains dormancy of human primary tumors in mice , 1996, Nature Medicine.

[13]  J. Isaacs,et al.  Role of programmed (apoptotic) cell death during the progression and therapy for prostate cancer , 1996, The Prostate.

[14]  S. Ojala,et al.  Isotope dilution gas chromatographic-mass spectrometric method for the determination of isoflavonoids, coumestrol, and lignans in food samples. , 1996, Analytical biochemistry.

[15]  K. Griffiths,et al.  Inhibition of 5 alpha-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids. , 1995, The Journal of endocrinology.

[16]  H. Thaler,et al.  Decreased growth of established human prostate LNCaP tumors in nude mice fed a low-fat diet. , 1995, Journal of the National Cancer Institute.

[17]  A. Bergh,et al.  Castration plus oestrogen treatment induces but castration alone suppresses epithelial cell apoptosis in an androgen-sensitive rat prostatic adenocarcinoma. , 1995, British Journal of Cancer.

[18]  H. Adlercreutz,et al.  Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis. , 1995, The Journal of nutrition.

[19]  H. Adlercreutz,et al.  Dietary soybean may be antiestrogenic in male mice. , 1995, The Journal of nutrition.

[20]  H. Adlercreutz,et al.  Isotope dilution gas chromatographic-mass spectrometric method for the determination of unconjugated lignans and isoflavonoids in human feces, with preliminary results in omnivorous and vegetarian women. , 1995, Analytical biochemistry.

[21]  Y. Homma,et al.  Promotional effect of two-generation exposure to a high-fat diet on prostate carcinogenesis in ACI/Seg rats. , 1994, Cancer research.

[22]  S. Wakui,et al.  Tumour angiogenesis in latent prostatic carcinoma. , 1994, British Journal of Cancer.

[23]  K. Pienta,et al.  An in vitro and in vivo study of antitumor effects of genistein on hormone refractory prostate cancer. , 1994, Anticancer research.

[24]  M. Landström,et al.  Prostatic tumor regrowth after initially successful castration therapy may be related to a decreased apoptotic cell death rate. , 1994, Cancer research.

[25]  M. Landström,et al.  Estrogen treatment postpones the castration‐induced dedifferentiation of dunning R3327‐PAP prostatic adenocarcinoma , 1994, The Prostate.

[26]  H. Adlercreutz,et al.  Plasma concentrations of phyto-oestrogens in Japanese men , 1993, The Lancet.

[27]  J. H. Dierendonck,et al.  A new method to detect apoptosis in paraffin sections: in situ end-labeling of fragmented DNA. , 1993, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[28]  H. Adlercreutz,et al.  Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet. , 1991, The American journal of clinical nutrition.

[29]  H. Adlercreutz,et al.  Isotope dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of genistein. , 1991, Clinica chimica acta; international journal of clinical chemistry.

[30]  T. P. Pretlow,et al.  Transplantation of human prostatic carcinoma into nude mice in Matrigel. , 1991, Cancer research.

[31]  B. Henderson,et al.  Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County. , 1991, British Journal of Cancer.

[32]  R. Weindruch,et al.  The role of calories and caloric restriction in carcinogenesis. , 1991, Hematology/oncology clinics of North America.

[33]  J. Folkman What is the evidence that tumors are angiogenesis dependent? , 1990, Journal of the National Cancer Institute.

[34]  A. Jacquemin-Sablon,et al.  Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II. , 1989, Cancer research.

[35]  W. L. Beeson,et al.  Cohort study of diet, lifestyle, and prostate cancer in adventist men , 1989, Cancer.

[36]  R. Severson,et al.  A prospective study of demographics, diet, and prostate cancer among men of Japanese ancestry in Hawaii. , 1989, Cancer research.

[37]  M. Shibuya,et al.  Genistein, a specific inhibitor of tyrosine-specific protein kinases. , 1987, The Journal of biological chemistry.

[38]  Morris Pollard,et al.  Promotional effects of testosterone and high fat diet on the development of autochthonous prostate cancer in rats. , 1986, Cancer letters.

[39]  G. Murphy,et al.  LNCaP model of human prostatic carcinoma. , 1983, Cancer research.

[40]  G. Stemmermann,et al.  Geographic pathology of latent prostatic carcinoma , 1982, International journal of cancer.

[41]  P. Briand,et al.  The effect of estrone-progesterone treatment on cell proliferation kinetics of hormone-dependent GR mouse mammary tumors. , 1975, Cancer research.

[42]  J. Kerr,et al.  Deletion of cells by apoptosis during castration-induced involution of the rat prostate , 1973, Virchows Archiv. B, Cell pathology.

[43]  C. Huggins,et al.  Studies on prostatic cancer: I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate , 1941, CA: a cancer journal for clinicians.

[44]  M. Spitz,et al.  Phytoestrogen intake and prostate cancer: a case-control study using a new database. , 1999, Nutrition and cancer.

[45]  H. Adlercreutz,et al.  Erratum: Isotope dilution gas chromatographic-mass spectrometric method for the determination of unconjugated lignans and isoflavonoids in human feces, with preliminary results in omnivorous and vegetarian women (Analytical Biochemistry (1995) 225:1 (101-108)) , 1995 .

[46]  P. Pietinen,et al.  The 1992 Dietary Survey of Finnish Adults , 1994 .

[47]  Chung Lee,et al.  Growth of an androgen‐sensitive human prostate cancer cell line, LNCaP, in nude mice , 1993, The Prostate.

[48]  L. Thompson,et al.  Mammalian lignan production from various foods. , 1991, Nutrition and cancer.