2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Preamble and Transition to ACC/AHA Guidelines to Reduce Cardiovascular Risk S50 The goals of the American College of Cardiology (ACC) and the American Heart Association (AHA) are to prevent cardiovascular diseases (CVD); improve the management of people who have these diseases through professional education and research; and develop guidelines, standards, and policies that promote optimal patient care and cardiovascular health. Toward these objectives, the ACC and AHA have collaborated with the National Heart, Lung, and Blood Institute (NHLBI) and stakeholder and professional organizations to develop …

[1]  S. Peters,et al.  Improvements in risk stratification for the occurrence of cardiovascular disease by imaging subclinical atherosclerosis: a systematic review , 2011, Heart.

[2]  M. Rowen,et al.  Extent of jeopardized viable myocardium determined by myocardial perfusion imaging best predicts perioperative cardiac events in patients undergoing noncardiac surgery. , 1993, Journal of the American College of Cardiology.

[3]  S. Wild,et al.  Previous Coronary Stent Implantation and Cardiac Events in Patients Undergoing Noncardiac Surgery , 2010, Circulation. Cardiovascular interventions.

[4]  W. Kannel,et al.  An investigation of coronary heart disease in families. The Framingham offspring study. , 1979, American journal of epidemiology.

[5]  S. Tonstad,et al.  Predictiveness of body mass index for fatal coronary heart disease in men according to length of follow-up: A 21-year prospective cohort study , 2007, Scandinavian journal of public health.

[6]  Shah Ebrahim,et al.  JOINT ESC GUIDELINES 2016 European Guidelines on cardiovascular disease prevention in clinical practice – Web Addenda , 2016 .

[7]  Michael J. Pencina,et al.  Predicting the 30-Year Risk of Cardiovascular Disease: The Framingham Heart Study , 2009, Circulation.

[8]  E. Halm,et al.  Echocardiography for Assessing Cardiac Risk in Patients Having Noncardiac Surgery , 1996, Annals of Internal Medicine.

[9]  A. A. Castro,et al.  Neuraxial anaesthesia for lower-limb revascularization. , 2013, The Cochrane database of systematic reviews.

[10]  Giel Nijpels,et al.  Common carotid intima-media thickness measurements in cardiovascular risk prediction: a meta-analysis. , 2012, JAMA.

[11]  H. Halperin,et al.  Effects of Surgical and Endoscopic Electrocautery on Modern‐Day Permanent Pacemaker and Implantable Cardioverter‐Defibrillator Systems , 2008, Pacing and clinical electrophysiology : PACE.

[12]  K. Chandrasekaran,et al.  Impact of pulmonary hypertension on the outcomes of noncardiac surgery: predictors of perioperative morbidity and mortality. , 2005, Journal of the American College of Cardiology.

[13]  M. Hersberger,et al.  Adrenergic Receptor Genotype but Not Perioperative Bisoprolol Therapy May Determine Cardiovascular Outcome in At-risk Patients Undergoing Surgery with Spinal Block: The Swiss Beta Blocker in Spinal Anesthesia (BBSA) Study: A Double-blinded, Placebo-controlled, Multicenter Trial with 1-Year Follow-up , 2007, Anesthesiology.

[14]  B. Yawn,et al.  Aspirin for the prevention of cardiovascular disease: U.S. Preventive Services Task Force recommendation statement. , 2009 .

[15]  B. Mainzer,et al.  Small, Oral Dose of Clonidine Reduces the Incidence of Intraoperative Myocardial Ischemia in Patients Having Vascular Surgery , 1996, Anesthesiology.

[16]  David Amar,et al.  Older Age Is the Strongest Predictor of Postoperative Atrial Fibrillation , 2002, Anesthesiology.

[17]  E. Walker,et al.  Pulmonary hypertension: an important predictor of outcomes in patients undergoing non-cardiac surgery. , 2011, Respiratory medicine.

[18]  I. R. Thomson,et al.  Failure of Intravenous Nitroglycerin to Prevent Intraoperative Myocardial Ischemia during Fentanyl–Pancuronium Anesthesia , 1984, Anesthesiology.

[19]  R. Peters,et al.  Routine preoperative exercise testing in patients undergoing major noncardiac surgery. , 1985, The American journal of cardiology.

[20]  D. Atkinson,et al.  Cardiopulmonary exercise testing for preoperative risk assessment before hepatic resection , 2012, The British journal of surgery.

[21]  C N McCollum,et al.  Preoperative cardiopulmonary exercise testing and risk of early mortality following abdominal aortic aneurysm repair , 2012, The British journal of surgery.

[22]  T. Bunt Perioperative and late outcome in patients with left ventricular ejection fraction of 35% or less who require major vascular surgery. , 1989, Journal of vascular surgery.

[23]  P. L. Petersen,et al.  Effect of perioperative β blockade in patients with diabetes undergoing major non-cardiac surgery: randomised placebo controlled, blinded multicentre trial , 2006, BMJ : British Medical Journal.

[24]  A. Wallace,et al.  Effect of atenolol on mortality and cardiovascular morbidity after noncardiac surgery. Multicenter Study of Perioperative Ischemia Research Group. , 1996, The New England journal of medicine.

[25]  D. Levy,et al.  Prediction of coronary heart disease using risk factor categories. , 1998, Circulation.

[26]  D. Shindler,et al.  The utility of dobutamine echocardiography in preoperative evaluation for elective aortic surgery. , 1997, American journal of surgery.

[27]  M. Sydes,et al.  Perioperative beta-blockade (POBBLE) for patients undergoing infrarenal vascular surgery: results of a randomized double-blind controlled trial. , 2005, Journal of vascular surgery.

[28]  París,et al.  Drug-eluting stent thrombosis in patients undergoing non-cardiac surgery: is it always a problem? , 2008, British journal of anaesthesia.

[29]  M. Pencina,et al.  Incidence and clinical outcome of minor surgery in the year after drug-eluting stent implantation: results from the Evaluation of Drug-Eluting Stents and Ischemic Events Registry. , 2011, American heart journal.

[30]  Mylan C. Cohen,et al.  Perioperative and long-term prognostic value of dipyridamole Tc-99m sestamibi myocardial tomography in patients evaluated for elective vascular surgery , 2003, Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.

[31]  Frederick A. Masoudi,et al.  ACCF/SCAI/STS/MTS/AHA/ASNC 2009 Appropriateness Criteria for Coronary Revascularization. Commentary , 2009 .

[32]  M. Zinner,et al.  Multivariable predictors of postoperative venous thromboembolic events after general and vascular surgery: results from the patient safety in surgery study. , 2007, Journal of the American College of Surgeons.

[33]  J. Roth,et al.  Risk factors associated with atrial fibrillation after noncardiac thoracic surgery: analysis of 2588 patients. , 2004, The Journal of thoracic and cardiovascular surgery.

[34]  G. Dumanian,et al.  Resident Involvement and Plastic Surgery Outcomes: An Analysis of 10,356 Patients from the American College of Surgeons National Surgical Quality Improvement Program Database , 2013, Plastic and reconstructive surgery.

[35]  A. Peyser,et al.  Preoperative Cardiac Events in Elderly Patients with Hip Fracture Randomized to Epidural or Conventional Analgesia , 2003, Anesthesiology.

[36]  J. Stockman,et al.  A New Equation to Estimate Glomerular Filtration Rate , 2011 .

[37]  K. Rieger,et al.  A randomized trial evaluating amiodarone for prevention of atrial fibrillation after pulmonary resection. , 2009, The Annals of thoracic surgery.

[38]  E F Cook,et al.  Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. , 1999, Circulation.

[39]  Emmanuel Touzé,et al.  Inclusion of stroke in cardiovascular risk prediction instruments: a statement for healthcare professionals from the American Heart Association/American Stroke Association. , 2012, Stroke.

[40]  C. O'connor,et al.  Impact of Heart Failure on Patients Undergoing Major Noncardiac Surgery , 2008, Anesthesiology.

[41]  E. Cook,et al.  Usefulness of transthoracic echocardiography as a tool for risk stratification of patients undergoing major noncardiac surgery. , 2001, The American journal of cardiology.

[42]  R. Gibbons,et al.  Supine exercise capacity identifies patients at low risk for perioperative cardiovascular events and predicts long-term survival. , 2000, The American journal of medicine.

[43]  임재영,et al.  BMI(Body Mass Index)가 소득에 미치는 영향 , 2012 .

[44]  F. Martinez,et al.  Dobutamine stress echocardiography for the preoperative evaluation of patients undergoing lung volume reduction surgery. , 1999, The Journal of thoracic and cardiovascular surgery.

[45]  J. Takeda,et al.  Nicorandil decreases cardiac events during and after noncardiac surgery. , 2007, Journal of clinical anesthesia.

[46]  S. Kapadia,et al.  Prognosis of patients with vascular disease after clinical evaluation and dobutamine stress echocardiography. , 1999, American heart journal.

[47]  Robert Dufour,et al.  Canadian Cardiovascular Society / Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult – 2009 recommendations , 2009 .

[48]  Aric Invest The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators , 1989 .

[49]  M. Humbert,et al.  Noncardiothoracic nonobstetric surgery in mild-to-moderate pulmonary hypertension , 2009, European Respiratory Journal.

[50]  C. Jakobsen,et al.  Perioperative metoprolol reduces the frequency of atrial fibrillation after thoracotomy for lung resection. , 1997, Journal of cardiothoracic and vascular anesthesia.

[51]  H. Nathoe,et al.  Myocardial Injury After Noncardiac Surgery and its Association With Short-Term Mortality , 2013, Circulation.

[52]  R. Pringle,et al.  The role of the routine pre-operative electrocardiogram in the elderly surgical patient. , 1983, Age and ageing.

[53]  J. Tinker,et al.  Applicability and interpretation of electrocardiographic stress testing in patients with peripheral vascular disease. , 1981, American journal of surgery.

[54]  D. Waters,et al.  Preoperative coronary artery disease risk stratification based on dipyridamole imaging and a simple three-step, three-segment model for patients undergoing noncardiac vascular surgery or major general surgery. , 1992, The American journal of cardiology.

[55]  J. Danesh,et al.  C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis , 2010, The Lancet.

[56]  S. Saba,et al.  Perioperative risk of noncardiac surgery associated with aortic stenosis. , 2005, The American journal of cardiology.

[57]  E. Vartiainen,et al.  Headache and the risk of stroke: a prospective observational cohort study among 35,056 Finnish men and women. , 2003, Archives of internal medicine.

[58]  Stacey L Sheridan,et al.  Does the routine use of global coronary heart disease risk scores translate into clinical benefits or harms? A systematic review of the literature , 2008, BMC health services research.

[59]  E. Vicaut,et al.  Dipyridamole-thallium scintigraphy and gated radionuclide angiography to assess cardiac risk before abdominal aortic surgery. , 1994, The New England journal of medicine.

[60]  H. Yamaue,et al.  Atrial fibrillation after esophageal cancer surgery: an analysis of 207 consecutive patients , 2014, Surgery Today.

[61]  L. Goldman,et al.  Supraventricular Arrhythmia in Patients Having Noncardiac Surgery: Clinical Correlates and Effect on Length of Stay , 1998, Annals of Internal Medicine.

[62]  A. M. Leone,et al.  Outcome of non-cardiac surgery after stent implantation in the DES era: results of the Surgery After Stent (SAS) registry. , 2011, The Journal of invasive cardiology.

[63]  R. J. Valentine,et al.  Effectiveness of pulmonary artery catheters in aortic surgery: a randomized trial. , 1998, Journal of vascular surgery.

[64]  M. Zornow,et al.  Low Utility of Dobutamine Stress Echocardiograms in the Preoperative Evaluation of Patients Scheduled for Noncardiac Surgery , 2002, Anesthesia and analgesia.

[65]  R. Wiklund,et al.  Activities of daily living and cardiovascular complications following elective, noncardiac surgery. , 2001, The Yale journal of biology and medicine.

[66]  D. Davenport,et al.  Thirty-day NSQIP database outcomes of open versus endoluminal repair of ruptured abdominal aortic aneurysms. , 2010, Journal of vascular surgery.

[67]  Ian Graham,et al.  EUROPEAN GUIDELINES ON CARDIOVASCULAR DISEASE PREVENTION IN CLINICAL PRACTICE , 2005 .

[68]  Denis Xavier,et al.  Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial , 2008, The Lancet.

[69]  Ralph B D'Agostino,et al.  Prediction of Lifetime Risk for Cardiovascular Disease by Risk Factor Burden at 50 Years of Age , 2006, Circulation.

[70]  E. Schick,et al.  Cardiac events in patients with negative maximal versus negative submaximal dobutamine echocardiograms undergoing noncardiac surgery: importance of resting wall motion abnormalities. , 2004, Journal of the American College of Cardiology.

[71]  U. Siebert,et al.  Prognostic value, clinical effectiveness, and cost-effectiveness of high-sensitivity C-reactive protein as a marker for major cardiac events in asymptomatic individuals: A health technology assessment report , 2010, International Journal of Technology Assessment in Health Care.

[72]  Zahi A Fayad,et al.  2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. , 2010, Journal of the American College of Cardiology.

[73]  M. Pfisterer,et al.  Long-term prognostic value of the preoperative 12-lead electrocardiogram before major noncardiac surgery in coronary artery disease. , 2006, American heart journal.

[74]  S. Greenfield,et al.  Clinical practice guidelines we can trust , 2011 .

[75]  S. Grundy,et al.  National Cholesterol Education Program Third Report of the National Cholesterol Education Program ( NCEP ) Expert Panel on Detection , Evaluation , and Treatment of High Blood Cholesterol in Adults ( Adult Treatment Panel III ) Final Report , 2022 .

[76]  B. Winters,et al.  &ggr;‐Adrenergic Blockade Accelerates Conversion of Postoperative Supraventricular Tachyarrhythmias , 1998, Anesthesiology.

[77]  C. O'connor,et al.  Outcomes in heart failure patients after major noncardiac surgery. , 2004, Journal of the American College of Cardiology.

[78]  S B Hulley,et al.  CARDIA: study design, recruitment, and some characteristics of the examined subjects. , 1988, Journal of clinical epidemiology.

[79]  Wen‐qi Huang,et al.  [Beneficial effects of metoprolol on perioperative cardiac function of elderly esophageal cancer patients]. , 2006, Ai zheng = Aizheng = Chinese journal of cancer.

[80]  K. Rieger,et al.  A randomized, controlled study of amiodarone for prevention of atrial fibrillation after transthoracic esophagectomy. , 2010, The Journal of thoracic and cardiovascular surgery.

[81]  H. Stratmann,et al.  Dipyridamole technetium-99m sestamibi myocardial tomography in patients evaluated for elective vascular surgery: prognostic value for perioperative and late cardiac events. , 1996, American heart journal.

[82]  B. Caramelli,et al.  Reduction in cardiovascular events after vascular surgery with atorvastatin: a randomized trial. , 2005, Journal of vascular surgery.

[83]  Jennifer G. Robinson,et al.  2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines , 2014, Journal of the American College of Cardiology.

[84]  K. Brasel,et al.  Postoperative atrial fibrillation in noncardiothoracic surgical patients. , 2001, American journal of surgery.

[85]  M. Pencina,et al.  Frequency of major noncardiac surgery and subsequent adverse events in the year after drug-eluting stent placement results from the EVENT (Evaluation of Drug-Eluting Stents and Ischemic Events) Registry. , 2010, JACC. Cardiovascular interventions.

[86]  M. Cerqueira,et al.  The role of preoperative radionuclide left ventricular ejection fraction for risk assessment in carotid surgery. , 1988, Archives of surgery.

[87]  L. Fleisher,et al.  Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events. A randomized clinical trial. , 1997, JAMA.

[88]  S. Garcia,et al.  Prognostic value of 12-lead electrocardiogram and peak troponin I level after vascular surgery. , 2013, Journal of vascular surgery.

[89]  A. Dyer,et al.  Association of traditional risk factors with cardiovascular death across 0 to 10, 10 to 20, and >20 years follow-up in men and women. , 2008, The American journal of cardiology.

[90]  A. Dyer,et al.  Major Risk Factors as Antecedents of Fatal and Nonfatal Coronary Heart Disease Events , 2003 .

[91]  Rongwei Fu,et al.  Emerging Risk Factors for Coronary Heart Disease: A Summary of Systematic Reviews Conducted for the U.S. Preventive Services Task Force , 2009, Annals of Internal Medicine.

[92]  S. Ellis,et al.  Characterization of post-operative risk associated with prior drug-eluting stent use. , 2009, JACC. Cardiovascular interventions.

[93]  A. Zangrillo,et al.  Volatile agents for cardiac protection in noncardiac surgery: a randomized controlled study. , 2011, Journal of Cardiothoracic and Vascular Anesthesia.

[94]  P. Kligfield,et al.  Postoperative Prophylactic Administration of &bgr;-Adrenergic Blockers in Patients at Risk for Myocardial Ischemia , 2000, Anesthesia and analgesia.

[95]  G. Guyatt,et al.  Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery. , 2012, JAMA.

[96]  D. S. Kitz,et al.  The utility of preoperative electrocardiograms in the ambulatory surgical patient. , 1992, Archives of internal medicine.

[97]  K. Eagle,et al.  Impact of adding aspirin to beta-blocker and statin in high-risk patients undergoing major vascular surgery. , 2013, Annals of vascular surgery.

[98]  J. Velly,et al.  Perioperative in-stent thrombosis after lung resection performed within 3 months of coronary stenting. , 2006, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[99]  N. Paynter,et al.  C-Reactive Protein and Parental History Improve Global Cardiovascular Risk Prediction: The Reynolds Risk Score for Men , 2008, Circulation.

[100]  Anthony J Viera,et al.  The effect of giving global coronary risk information to adults: a systematic review. , 2010, Archives of internal medicine.

[101]  Jennifer G. Robinson,et al.  2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. , 2014, Circulation.

[102]  苅尾 七臣,et al.  ガイドライン解説 AHA/ACCF secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease : 2011 update , 2012 .

[103]  M. Kontos,et al.  Cardiac complications in noncardiac surgery: relative value of resting two-dimensional echocardiography and dipyridamole thallium imaging. , 1996, American Heart Journal.

[104]  Jeroen J. Bax,et al.  Timing of noncardiac surgery after coronary artery stenting with bare metal or drug-eluting stents. , 2009, The American journal of cardiology.

[105]  Arthur W Wallace,et al.  Effect of Clonidine on Cardiovascular Morbidity and Mortality after Noncardiac Surgery , 2004, Anesthesiology.

[106]  P. Vaitkus,et al.  Risks of noncardiac surgery after coronary stenting. , 2005, The American journal of cardiology.

[107]  L. Goldman,et al.  Statin use and postoperative atrial fibrillation after major noncardiac surgery. , 2012, Heart rhythm.

[108]  A. Zangrillo,et al.  Cardiac protection by volatile anesthetics in non-cardiac surgery? A meta-analysis of randomized controlled studies on clinically relevant endpoints , 2009, HSR proceedings in intensive care & cardiovascular anesthesia.

[109]  M. Nobuyoshi,et al.  Incidence and Outcome of Surgical Procedures After Coronary Bare-Metal and Drug-Eluting Stent Implantation: A Report From the CREDO-Kyoto PCI/CABG Registry Cohort-2 , 2012, Circulation. Cardiovascular interventions.

[110]  Thomas E. Moritz,et al.  Coronary-artery revascularization before elective major vascular surgery. , 2004, The New England journal of medicine.

[111]  R. Green,et al.  Predictive value of dobutamine echocardiography just before noncardiac vascular surgery. , 1993, The American journal of cardiology.

[112]  G. Nuttall,et al.  Cardiac Risk of Noncardiac Surgery after Percutaneous Coronary Intervention with Drug-eluting Stents , 2008, Anesthesiology.

[113]  D. N. Buckley,et al.  A Meta-Analytic Comparison of Preoperative Stress Echocardiography and Nuclear Scintigraphy Imaging , 2006, Anesthesia and analgesia.

[114]  L. Goldman,et al.  Effect of mivazerol on perioperative cardiac complications during non-cardiac surgery in patients with coronary heart disease: the European Mivazerol Trial (EMIT). , 1999, Anesthesiology.

[115]  M. Lauer,et al.  Refocusing the agenda on cardiovascular guidelines: an announcement from the National Heart, Lung, and Blood Institute. , 2013, Circulation.

[116]  D. Schroeder,et al.  Time and Cardiac Risk of Surgery after Bare-metal Stent Percutaneous Coronary Intervention , 2008, Anesthesiology.

[117]  Jeroen J. Bax,et al.  The effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group. , 1999, The New England journal of medicine.

[118]  M. Humbert,et al.  Outcomes of noncardiac, nonobstetric surgery in patients with PAH: an international prospective survey , 2012, European Respiratory Journal.

[119]  J. Bender,et al.  Routine pulmonary artery catheterization does not reduce morbidity and mortality of elective vascular surgery: results of a prospective, randomized trial. , 1997, Annals of surgery.

[120]  H. Tunstall-Pedoe,et al.  Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. , 2003, European heart journal.

[121]  G. Biondi-Zoccai,et al.  The effect of isoflurane on survival and myocardial infarction: a meta-analysis of randomized controlled studies. , 2013, Journal of cardiothoracic and vascular anesthesia.

[122]  A. Dyer,et al.  Major risk factors as antecedents of fatal and nonfatal coronary heart disease events. , 2003, JAMA.

[123]  M. Farkouh,et al.  Use of clinically based troponin underestimates the cardiac injury in non-cardiac surgery: a single-centre cohort study in 51,701 consecutive patients , 2012, Canadian Journal of Anesthesia/Journal canadien d'anesthésie.

[124]  R. Kronmal,et al.  The Cardiovascular Health Study: design and rationale. , 1991, Annals of epidemiology.

[125]  Robert Dufour,et al.  2012 update of the Canadian Cardiovascular Society guidelines for the diagnosis and treatment of dyslipidemia for the prevention of cardiovascular disease in the adult. , 2013, The Canadian journal of cardiology.

[126]  J. Seward,et al.  Assessment of cardiac risk before nonvascular surgery: dobutamine stress echocardiography in 530 patients. , 2000, Journal of the American College of Cardiology.

[127]  C. Herzog,et al.  Troponin I Levels and Postoperative Myocardial Infarction following Renal Transplantation , 2012, American Journal of Nephrology.

[128]  G. Ambrosio,et al.  Systematic strategy of prophylactic coronary angiography improves long-term outcome after major vascular surgery in medium- to high-risk patients: a prospective, randomized study. , 2009, Journal of the American College of Cardiology.

[129]  Elena Bignami,et al.  Desflurane and sevoflurane in cardiac surgery: a meta-analysis of randomized clinical trials. , 2007, Journal of cardiothoracic and vascular anesthesia.

[130]  A. Kurz,et al.  Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. Study of Wound Infection and Temperature Group. , 1996, The New England journal of medicine.

[131]  M. Watkins,et al.  Preoperative functional status predicts perioperative outcomes after infrainguinal bypass surgery. , 2010, Journal of vascular surgery.

[132]  N. Cook,et al.  Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk Score. , 2007, JAMA.

[133]  J. Elmore,et al.  Dobutamine stress echocardiography for cardiac risk assessment before aortic surgery. , 1993, Journal of vascular surgery.

[134]  D. Sessler,et al.  Angiotensin Converting Enzyme Inhibitors Are Not Associated with Respiratory Complications or Mortality After Noncardiac Surgery , 2012, Anesthesia and analgesia.

[135]  C. Schmid,et al.  An assessment of the positive predictive value and cost-effectiveness of dipyridamole myocardial scintigraphy in patients undergoing vascular surgery. , 1994, Journal of vascular surgery.

[136]  D. Wortham,et al.  A Perioperative Management Algorithm for Cardiac Rhythm Management Devices: The PACED‐OP Protocol , 2013, Pacing and clinical electrophysiology : PACE.

[137]  C. Furberg,et al.  A Meta-Analysis of Low-Density Lipoprotein Cholesterol, Non-High-Density Lipoprotein Cholesterol, and Apolipoprotein B as Markers of Cardiovascular Risk , 2011, Circulation. Cardiovascular quality and outcomes.

[138]  T. Wadden,et al.  Reprint: 2013 AHA/ACC Guideline on Lifestyle Management to Reduce Cardiovascular Risk. , 2014, Journal of the American Pharmacists Association : JAPhA.

[139]  A. Folsom,et al.  The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators. , 1989, American journal of epidemiology.

[140]  Robert F Kushner,et al.  2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. , 2014, Journal of the American College of Cardiology.

[141]  E. Tuzcu,et al.  Impact of severe mitral regurgitation on postoperative outcomes after noncardiac surgery. , 2013, The American journal of medicine.

[142]  George A Wells,et al.  The Value of Routine Preoperative Electrocardiography in Predicting Myocardial Infarction After Noncardiac Surgery , 2007, Annals of surgery.

[143]  J. Ruidavets,et al.  Predicting CHD risk in France: a pooled analysis of the D.E.S.I.R., Three City, PRIME, and SU.VI.MAX studies , 2011, European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology.

[144]  Sean M. O'Brien,et al.  Risk factors for atrial fibrillation after lung cancer surgery: analysis of the Society of Thoracic Surgeons general thoracic surgery database. , 2010, The Annals of thoracic surgery.

[145]  Zahi A Fayad,et al.  2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. , 2010, Circulation.

[146]  M. Pencina,et al.  General Cardiovascular Risk Profile for Use in Primary Care: The Framingham Heart Study , 2008, Circulation.

[147]  Julio E. Pérez,et al.  Dobutamine stress echocardiography predicts surgical outcome in patients with an aortic aneurysm and peripheral vascular disease. , 1993, Journal of the American College of Cardiology.

[148]  A. Zangrillo,et al.  Myocardial damage prevented by volatile anesthetics: a multicenter randomized controlled study. , 2006, Journal of cardiothoracic and vascular anesthesia.

[149]  A. Munafo,et al.  Prevention of arrhythmias after noncardiac thoracic operations: flecainide versus digoxin. , 1991, The Annals of thoracic surgery.

[150]  R. Adolph,et al.  Cardiac prognosis in noncardiac geriatric surgery. , 1985, Annals of internal medicine.

[151]  D. Simons-Morton,et al.  Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents: Summary Report , 2011, Pediatrics.

[152]  Christopher L. Wu,et al.  Effect of Postoperative Epidural Analgesia on Morbidity and Mortality After Total Hip Replacement Surgery in Medicare Patients , 2003, Regional Anesthesia & Pain Medicine.

[153]  J. Mckenney,et al.  National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) , 2002 .

[154]  John J. Park,et al.  Frequency of late drug-eluting stent thrombosis with non-cardiac surgery. , 2010, The American journal of cardiology.

[155]  Paul Stolee,et al.  Frailty is associated with postoperative complications in older adults with medical problems. , 2009, Archives of gerontology and geriatrics.

[156]  J. Leung,et al.  Relative Importance of Preoperative Health Status Versus Intraoperative Factors in Predicting Postoperative Adverse Outcomes in Geriatric Surgical Patients , 2001, Journal of the American Geriatrics Society.

[157]  Subhash Banerjee,et al.  Frequency and risk of noncardiac surgery after drug‐eluting stent implantation , 2011, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[158]  Guohua Li,et al.  Intraoperative Cardiac Arrests in Adults Undergoing Noncardiac Surgery: Incidence, Risk Factors, and Survival Outcome , 2012, Anesthesiology.

[159]  A Hofman,et al.  Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis. , 2008, JAMA.

[160]  R. Hendel,et al.  Prediction of late cardiac events by dipyridamole thallium imaging in patients undergoing elective vascular surgery. , 1992, The American journal of cardiology.

[161]  L. Fleisher,et al.  Perioperative Beta Blockade in Noncardiac Surgery: A Systematic Review for the 2014 ACC/AHA Guideline on Perioperative Cardiovascular Evaluation and Management of Patients Undergoing Noncardiac Surgery A Report of the American College of Cardiology/American Heart Association Task Force on Practice G , 2014, Circulation.

[162]  Ralph B D'Agostino,et al.  Framingham risk score and prediction of lifetime risk for coronary heart disease. , 2004, The American journal of cardiology.

[163]  R. Hauser,et al.  Deaths associated with implantable cardioverter defibrillator failure and deactivation reported in the United States Food and Drug Administration Manufacturer and User Facility Device Experience Database. , 2004, Heart rhythm.

[164]  D. Brown,et al.  Risk of patients with severe aortic stenosis undergoing noncardiac surgery. , 1998, The American journal of cardiology.

[165]  T. Ryan,et al.  Dobutamine stress echocardiography for assessment of cardiac risk before noncardiac surgery. , 1991, The American journal of cardiology.

[166]  R. Brant,et al.  A randomized, controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients. , 2003, The New England journal of medicine.

[167]  Gillian Bartlett,et al.  Updated risk factor values and the ability of the multivariable risk score to predict coronary heart disease. , 2004, American journal of epidemiology.

[168]  H. Jensen,et al.  Amiodarone significantly decreases atrial fibrillation in patients undergoing surgery for lung cancer. , 2012, The Annals of thoracic surgery.

[169]  Pd Hayes,et al.  Cardiopulmonary exercise testing provides a predictive tool for early and late outcomes in abdominal aortic aneurysm patients , 2012, Annals of the Royal College of Surgeons of England.

[170]  Robert A. Smith,et al.  Preoperative Evaluation of Cardiac Failure and Ischemia in Elderly Patients by Cardiopulmonary Exercise Testing , 1993, Chest.

[171]  M. Shishehbor,et al.  Statin Therapy in the Reduction of Cardiovascular Events in Patients Undergoing Intermediate‐Risk Noncardiac, Nonvascular Surgery , 2013, Clinical cardiology.

[172]  S. Cotev,et al.  Perioperative ischemia and cardiac complications in major vascular surgery: importance of the preoperative twelve-lead electrocardiogram. , 1997, Journal of vascular surgery.

[173]  Jon S Thompson,et al.  Effect of Epidural Anesthesia and Analgesia on Perioperative Outcome: A Randomized, Controlled Veterans Affairs Cooperative Study , 2001, Annals of surgery.

[174]  R. Gibbons,et al.  Guidelines for perioperative cardiovascular evaluation for noncardiac surgery. Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Perioperative Cardiovascular Evaluation for Noncardiac Surgery). , 1996, Journal of the American College of Cardiology.

[175]  J. Calvin,et al.  The use of preoperative exercise testing to predict cardiac complications after arterial reconstruction. , 1988, Journal of vascular surgery.

[176]  M. Hawn,et al.  Risk of major adverse cardiac events following noncardiac surgery in patients with coronary stents. , 2013, JAMA.

[177]  H. Thaler,et al.  Statin use is associated with a reduction in atrial fibrillation after noncardiac thoracic surgery independent of C-reactive protein. , 2005, Chest.

[178]  B. Hindman,et al.  Perioperative Hypothermia (33°C) Does Not Increase the Occurrence of Cardiovascular Events in Patients Undergoing Cerebral Aneurysm Surgery: Findings from the Intraoperative Hypothermia for Aneurysm Surgery Trial , 2010, Anesthesiology.

[179]  L. Goldman,et al.  Incidence, predictors, and outcomes associated with postoperative atrial fibrillation after major noncardiac surgery. , 2012, American heart journal.

[180]  R. Kornowski,et al.  The risk of cardiac complications following noncardiac surgery in patients with drug eluting stents implanted at least six months before surgery , 2009, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[181]  J. Turnbull,et al.  The value of preoperative screening investigations in otherwise healthy individuals. , 1987, Archives of internal medicine.

[182]  W. Klein,et al.  Perioperative Ventricular Dysrhythmias in Patients with Structural Heart Disease Undergoing Noncardiac Surgery , 1998, Anesthesia and analgesia.

[183]  T. Marwick,et al.  Usefulness of clinical risk markers and ischemic threshold to stratify risk in patients undergoing major noncardiac surgery. , 2002, The American journal of cardiology.

[184]  Denis Xavier,et al.  Characteristics and Short-Term Prognosis of Perioperative Myocardial Infarction in Patients Undergoing Noncardiac Surgery , 2011, Annals of Internal Medicine.

[185]  A. Arroliga,et al.  Surgical intervention in patients with moderate to severe pulmonary arterial hypertension. , 2006, Connecticut medicine.

[186]  B. Massie,et al.  Ventricular arrhythmias in patients undergoing noncardiac surgery. The Study of Perioperative Ischemia Research Group. , 1992, JAMA.

[187]  G. Godet,et al.  Roles of Fentanyl and Nitroglycerin in Prevention of Myocardial Ischemia Associated with Laryngoscopy and Tracheal Intubation in Patients Undergoing Operations of Short Duration , 1986, Anesthesia and analgesia.

[188]  C. Detter,et al.  Sevoflurane Provides Greater Protection of the Myocardium than Propofol in Patients Undergoing Off-pump Coronary Artery Bypass Surgery , 2003, Anesthesiology.

[189]  Richard W Morris,et al.  Metabolic syndrome vs Framingham Risk Score for prediction of coronary heart disease, stroke, and type 2 diabetes mellitus. , 2005, Archives of internal medicine.

[190]  P. Alderson,et al.  Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery. , 2013, The Cochrane database of systematic reviews.

[191]  F. McAlister,et al.  Mortality and Readmission of Patients With Heart Failure, Atrial Fibrillation, or Coronary Artery Disease Undergoing Noncardiac Surgery: An Analysis of 38 047 Patients , 2011, Circulation.

[192]  A. Weiss,et al.  Effect of Severe Aortic Stenosis on the Outcome in Elderly Patients Undergoing Repair of Hip Fracture , 2009, Gerontology.

[193]  Mark D. Huffman,et al.  Heart disease and stroke statistics--2013 update: a report from the American Heart Association. , 2013, Circulation.

[194]  R. Hader,et al.  Cardiopulmonary exercise testing as a screening test for perioperative management of major surgery in the elderly. , 1999, Chest.

[195]  Shah Ebrahim,et al.  European Guidelines on Cardiovascular Disease Prevention in Clinical Practice (Version 2012) , 2012, International Journal of Behavioral Medicine.

[196]  M. Lauer,et al.  Refocusing the agenda on cardiovascular guidelines: an announcement from the National Heart, Lung, and Blood Institute. , 2013, Journal of the American College of Cardiology.

[197]  C. Phillips,et al.  Outcomes of patients with stable heart failure undergoing elective noncardiac surgery. , 2008, Mayo Clinic proceedings.

[198]  Jeroen J. Bax,et al.  Bisoprolol and Fluvastatin for the Reduction of Perioperative Cardiac Mortality and Myocardial Infarction in Intermediate-Risk Patients Undergoing Noncardiovascular Surgery: A Randomized Controlled Trial (DECREASE-IV) , 2009, Annals of surgery.

[199]  A. Raizner,et al.  Catastrophic outcomes of noncardiac surgery soon after coronary stenting. , 2000, Journal of the American College of Cardiology.

[200]  Rongwei Fu,et al.  C-Reactive Protein as a Risk Factor for Coronary Heart Disease: A Systematic Review and Meta-analyses for the U.S. Preventive Services Task Force , 2009, Annals of Internal Medicine.

[201]  K.Y. Wang,et al.  Impact of chronic advanced aortic regurgitation on the perioperative outcome of noncardiac surgery , 2010, Acta anaesthesiologica Scandinavica.

[202]  D. Lloyd‐Jones,et al.  Systematic Examination of the Updated Framingham Heart Study General Cardiovascular Risk Profile , 2009, Circulation.

[203]  Ersen B. Colkesen,et al.  Systematic review of guidelines on imaging of asymptomatic coronary artery disease. , 2011, Journal of the American College of Cardiology.

[204]  L. Christenson,et al.  Pacemakers and Implantable Cardiac Defibrillators in Dermatologic Surgery , 2006, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[205]  M. Schermerhorn,et al.  Sex-related differences in outcome after high-risk vascular surgery after the administration of beta-adrenergic-blocking drugs. , 2008, Journal of cardiothoracic and vascular anesthesia.

[206]  C. Meinert,et al.  Double-masked Randomized Trial Comparing Alternate Combinations of Intraoperative Anesthesia and Postoperative Analgesia in Abdominal Aortic Surgery , 2001, Anesthesiology.

[207]  R. Beaglehole,et al.  The real contribution of the major risk factors to the coronary epidemics: time to end the "only-50%" myth. , 2001, Archives of internal medicine.

[208]  D. Duman,et al.  Predictive Value of Preoperative Electrocardiography for Perioperative Cardiovascular Outcomes in Patients Undergoing Noncardiac, Nonvascular Surgery , 2012, Clinical cardiology.

[209]  B. Biccard,et al.  Outcomes in vascular surgical patients with isolated postoperative troponin leak: a meta‐analysis , 2011, Anaesthesia.

[210]  A. Menotti,et al.  Coronary risk factors predicting early and late coronary deaths , 2003, Heart.

[211]  J. Katz,et al.  The value of routine preoperative medical testing before cataract surgery. Study of Medical Testing for Cataract Surgery. , 2000, The New England journal of medicine.

[212]  Linda L. Liu,et al.  Preoperative Electrocardiogram Abnormalities Do Not Predict Postoperative Cardiac Complications in Geriatric Surgical Patients , 2002, Journal of the American Geriatrics Society.

[213]  M. Nishimori,et al.  Epidural Pain Relief Versus Systemic Opioid-Based Pain Relief for Abdominal Aortic Surgery , 2006, The Cochrane database of systematic reviews.

[214]  H. Wijeysundera,et al.  Risk of Elective Major Noncardiac Surgery After Coronary Stent Insertion: A Population-Based Study , 2012, Circulation.

[215]  D. Massel,et al.  Propranolol for the prevention of postoperative arrhythmias in general thoracic surgery. , 1999, The Annals of thoracic surgery.

[216]  J. Chae,et al.  Drug-eluting stent thrombosis during perioperative period. , 2008, International heart journal.

[217]  G. Assmann,et al.  Simple Scoring Scheme for Calculating the Risk of Acute Coronary Events Based on the 10-Year Follow-Up of the Prospective Cardiovascular Münster (PROCAM) Study , 2002, Circulation.

[218]  J. Spertus,et al.  ACCF/SCAI/STS/AATS/AHA/ASNC/HFSA/SCCT 2012 Appropriate use criteria for coronary revascularization focused update: a report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, Society for Cardiovascular Angiography and Interventions, Society of Thoracic Surgeons, Am , 2012, Journal of the American College of Cardiology.

[219]  D. Lloyd‐Jones,et al.  Who exceeds ATP-III risk thresholds? Systematic examination of the effect of varying age and risk factor levels in the ATP-III risk assessment tool. , 2008, Preventive medicine.

[220]  Farris K. Timimi,et al.  The effect of heart rate control on myocardial ischemia among high-risk patients after vascular surgery. , 1999, Anesthesia and analgesia.

[221]  H. Weitz,et al.  Adenosine radionuclide perfusion imaging in the preoperative evaluation of patients undergoing peripheral vascular surgery. , 1995, The American journal of cardiology.

[222]  Stacey L. Sheridan,et al.  Use of global coronary heart disease risk assessment in practice: a cross-sectional survey of a sample of U.S. physicians , 2012, BMC Health Services Research.

[223]  Randolph P. Martin,et al.  Transthoracic Dobutamine Stress Echocardiography in Patients Undergoing Bariatric Surgery , 2007, Obesity surgery.

[224]  E. Spitznagel,et al.  Postoperative myocardial injury after major head and neck cancer surgery , 2011, Head & neck.

[225]  E. Blackstone,et al.  Atrial fibrillation complicating lung cancer resection. , 2005, The Journal of thoracic and cardiovascular surgery.

[226]  Qi Wang,et al.  [Effects of metoprolol on perioperative cardiovascular events in patients with risk or at high risk for coronary artery disease undergoing non-cardiac surgery]. , 2008, Zhonghua yi xue za zhi.

[227]  C. Snowden,et al.  Submaximal Cardiopulmonary Exercise Testing Predicts Complications and Hospital Length of Stay in Patients Undergoing Major Elective Surgery , 2010, Annals of surgery.

[228]  Janusz Wnek,et al.  2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. , 2014, Circulation.

[229]  M. Trenell,et al.  Cardiorespiratory Fitness Predicts Mortality and Hospital Length of Stay After Major Elective Surgery in Older People , 2013, Annals of surgery.

[230]  Allan S. Detsky,et al.  Predicting cardiac complications in patients undergoing non-cardiac surgery , 1986, Journal of General Internal Medicine.

[231]  P. Berger,et al.  Clinical outcome of patients undergoing non-cardiac surgery in the two months following coronary stenting. , 2003, Journal of the American College of Cardiology.

[232]  Subhash Banerjee,et al.  Risk of noncardiac surgery after coronary drug-eluting stent implantation. , 2006, The American journal of cardiology.

[233]  J. Spertus,et al.  ACCF/SCAI/STS/AATS/AHA/ASNC 2009 Appropriateness Criteria for Coronary Revascularization: a report by the American College of Cardiology Foundation Appropriateness Criteria Task Force, Society for Cardiovascular Angiography and Interventions, Society of Thoracic Surgeons, American Association for Th , 2009, Journal of the American College of Cardiology.

[234]  A. Laupacis,et al.  Non-invasive cardiac stress testing before elective major non-cardiac surgery: population based cohort study , 2010, BMJ : British Medical Journal.

[235]  D. Amar,et al.  The Incidence and Outcome of Ventricular Arrhythmias After Noncardiac Thoracic Surgery , 2002, Anesthesia and Analgesia.

[236]  M. Kashani,et al.  Improving Assessment of Cardiovascular Disease Risk by Using Family History: An Integrative Literature Review , 2013, The Journal of cardiovascular nursing.

[237]  J. Marty,et al.  Perioperative outcome of pacemaker patients undergoing non-cardiac surgery. , 2008, European journal of anaesthesiology.

[238]  F. Harrell,et al.  Criteria for Evaluation of Novel Markers of Cardiovascular Risk: A Scientific Statement From the American Heart Association , 2009, Circulation.

[239]  Hyuk-Jae Chang,et al.  Stent-related cardiac events after non-cardiac surgery: drug-eluting stent vs. bare metal stent. , 2008, International journal of cardiology.

[240]  John Spertus,et al.  AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients with Coronary and other Atherosclerotic Vascular Disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation. , 2011, Circulation.

[241]  C. Weissman,et al.  The new onset of atrial arrhythmias following major noncardiothoracic surgery is associated with increased mortality. , 1998, Chest.

[242]  P. Jousilahti Headache and the risk of stroke , 2004, Current atherosclerosis reports.

[243]  G. Guyatt,et al.  Prognostic Value of Troponin and Creatine Kinase Muscle and Brain Isoenzyme Measurement after Noncardiac Surgery: A Systematic Review and Meta-analysis , 2011, Anesthesiology.

[244]  E. Benjamin,et al.  AHA/ACCF [corrected] 2009 performance measures for primary prevention of cardiovascular disease in adults: a report of the American College of Cardiology Foundation/American Heart Association task force on performance measures (writing committee to develop performance measures for primary prevention , 2009, Circulation.

[245]  D. Yates,et al.  Impaired functional capacity is associated with all-cause mortality after major elective intra-abdominal surgery. , 2010, British journal of anaesthesia.

[246]  B. Chaitman,et al.  Perioperative and long-term prognostic value of intravenous dipyridamole thallium scintigraphy in patients with peripheral vascular disease. , 1990, American heart journal.

[247]  B. Sumer,et al.  Correlation between intraoperative hypothermia and perioperative morbidity in patients with head and neck cancer. , 2009, Archives of otolaryngology--head & neck surgery.

[248]  Mario J. Garcia,et al.  ACCF/SCAI/STS/AATS/AHA/ASNC 2009 Appropriateness Criteria for Coronary Revascularization , 2009, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[249]  D L McGee,et al.  How generalizable are coronary risk prediction models? Comparison of Framingham and two national cohorts. , 1999, American heart journal.

[250]  Yasuo Ohashi,et al.  Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis. , 2009, JAMA.

[251]  C. Schmid,et al.  A new equation to estimate glomerular filtration rate. , 2009, Annals of internal medicine.

[252]  P. Coriat,et al.  Low negative predictive value of dobutamine stress echocardiography before abdominal aortic surgery. , 2006, British journal of anaesthesia.

[253]  I. Rubinfeld,et al.  Preoperative risk stratification for thoracic surgery using the American College of Surgeons National Surgical Quality Improvement Program data set: functional status predicts morbidity and mortality. , 2012, The Journal of surgical research.

[254]  W. Kannel,et al.  AN APPROACH TO LONGITUDINAL STUDIES IN A COMMUNITY: THE FRAMINGHAM STUDY , 1963, Annals of the New York Academy of Sciences.

[255]  A. Martinoni,et al.  Atrial fibrillation after operation for lung cancer: clinical and prognostic significance. , 1999, The Annals of thoracic surgery.

[256]  Jeffrey L. Anderson,et al.  ACCF / AHA Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults , 2010 .

[257]  D. Reich,et al.  Beneficial effects from beta-adrenergic blockade in elderly patients undergoing noncardiac surgery. , 1999, Anesthesiology.

[258]  R. Peters,et al.  The preoperative electrocardiogram as an indicator of risk in major noncardiac surgery. , 1986, The Canadian journal of cardiology.

[259]  Shuang Wang,et al.  Perioperative Acute Ischemic Stroke in Noncardiac and Nonvascular Surgery: Incidence, Risk Factors, and Outcomes , 2009, Anesthesiology.

[260]  M. Pencina,et al.  Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond , 2008, Statistics in medicine.

[261]  P. Baum,et al.  The ischemic exercise test in patients with peripheral vascular disease. Implications for management. , 1985, Archives of surgery.

[262]  M. Trenell,et al.  Submaximal exercise testing predicts perioperative hospitalization after aortic aneurysm repair. , 2012, Journal of vascular surgery.

[263]  N. Orford,et al.  Perioperative Complications in Patients with Drug-Eluting Stents: A Three-Year Audit at Geelong Hospital , 2007, Anaesthesia and intensive care.

[264]  G. Mashour,et al.  Perioperative Stroke and Associated Mortality after Noncardiac, Nonneurologic Surgery , 2011, Anesthesiology.

[265]  David Ponka,et al.  Ankle-brachial index. , 2013, Canadian family physician Medecin de famille canadien.

[266]  J. Hentz,et al.  Preoperative dobutamine stress echocardiographic findings and subsequent short‐term adverse cardiac events after orthotopic liver transplantation , 2008, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[267]  P. Stetson,et al.  Perioperative outcome and long-term mortality for heart failure patients undergoing intermediate- and high-risk noncardiac surgery: impact of left ventricular ejection fraction. , 2010, Congestive Heart Failure.

[268]  J. Ioannidis,et al.  Comparison of effect sizes associated with biomarkers reported in highly cited individual articles and in subsequent meta-analyses. , 2011, JAMA.

[269]  J. Hippisley-Cox,et al.  Derivation and validation of QRISK, a new cardiovascular disease risk score for the United Kingdom: prospective open cohort study , 2007, BMJ : British Medical Journal.

[270]  C. Samama,et al.  Non-cardiac surgery in patients with coronary stents: the RECO study , 2011, Heart.

[271]  Homer Yang,et al.  The effects of perioperative beta-blockade: results of the Metoprolol after Vascular Surgery (MaVS) study, a randomized controlled trial. , 2006, American heart journal.

[272]  E. Tuzcu,et al.  Impact of Aortic Stenosis on Postoperative Outcomes After Noncardiac Surgeries , 2012, Circulation. Cardiovascular quality and outcomes.

[273]  V. Moyer Screening for Peripheral Artery Disease and Cardiovascular Disease Risk Assessment With the Ankle–Brachial Index in Adults: U.S. Preventive Services Task Force Recommendation Statement , 2013, Annals of Internal Medicine.

[274]  Thomas O. Staiger,et al.  Self-reported exercise tolerance and the risk of serious perioperative complications. , 1999, Archives of internal medicine.

[275]  R. Waksman,et al.  Major noncardiac surgery following coronary stenting: When is it safe to operate? , 2004, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[276]  G. Moneta,et al.  Major Lipids, Apolipoproteins, and Risk of Vascular Disease , 2010 .

[277]  J. Leppo,et al.  Noninvasive evaluation of cardiac risk before elective vascular surgery. , 1987, Journal of the American College of Cardiology.

[278]  J. Earnshaw,et al.  Lessons learned from a randomised controlled study of perioperative beta blockade in high risk patients undergoing emergency surgery. , 2006, The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland.

[279]  M. Jessup,et al.  The next steps in developing clinical practice guidelines for prevention. , 2013, Journal of the American College of Cardiology.

[280]  T. Ryan,et al.  Dobutamine stress echocardiography as a predictor of cardiac events associated with aortic surgery. , 1992, Journal of vascular surgery.

[281]  E. Benjamin,et al.  ACCF/AHA 2009 performance measures for primary prevention of cardiovascular disease in adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Performance Measures (Writing Committee to Develop Performance Measures for Primary Prevention of Cardiova , 2009, Journal of the American College of Cardiology.

[282]  Deepak L. Bhatt,et al.  Discontinuation of antiplatelet therapy prior to low-risk noncardiac surgery in patients with drug-eluting stents: a retrospective cohort study. , 2007, Journal of hospital medicine.

[283]  C. Ting,et al.  Severe pulmonary hypertension complicates postoperative outcome of non-cardiac surgery. , 2007, British journal of anaesthesia.

[284]  J. Carlisle,et al.  Mid-term survival after abdominal aortic aneurysm surgery predicted by cardiopulmonary exercise testing. , 2007, The British journal of surgery.

[285]  G. Steinbeck,et al.  Application of Radiofrequency Energy in Surgical and Interventional Procedures: , 2004, Pacing and clinical electrophysiology : PACE.

[286]  V. Rusch,et al.  Brain natriuretic peptide and risk of atrial fibrillation after thoracic surgery. , 2012, The Journal of thoracic and cardiovascular surgery.

[287]  L Goldman,et al.  Multifactorial index of cardiac risk in noncardiac surgical procedures. , 1977, The New England journal of medicine.

[288]  Jeroen J. Bax,et al.  Noncardiac surgery after coronary stenting: early surgery and interruption of antiplatelet therapy are associated with an increase in major adverse cardiac events. , 2007, Journal of the American College of Cardiology.

[289]  J. Coromilas,et al.  Prophylactic nitroglycerin infusion during noncardiac surgery does not reduce perioperative ischemia. , 1993, Anesthesia and analgesia.

[290]  S. Cha,et al.  Cardiac risk in patients aged >75 years with asymptomatic, severe aortic stenosis undergoing noncardiac surgery. , 2010, The American journal of cardiology.

[291]  A. Yamashina,et al.  Value of pharmacologic stress myocardial perfusion imaging for preoperative risk stratification for aortic surgery. , 2005, Circulation journal : official journal of the Japanese Circulation Society.