Primary cutaneous CD4+ small/medium T‐cell lymphoproliferative disorder in children: A case report and review of the literature

Primary cutaneous CD4+ small/medium T‐cell lymphoproliferative disorder (PCSM‐TCLPD) is a rare benign lymphoproliferative disorder, recently redefined by the 2016 World Health Organization classification of lymphoid neoplasms. In adults, PCSM‐TCLPD responds well to monotherapy with surgical excision or local radiation, with or without topical/injected corticosteroids; in contrast, PCSM‐TCLPD has only rarely been reported in children, in whom treatments favored in adults may be non‐optimal. We present a 14‐year‐old male with PCSM‐TCLPD on the forehead, who achieved complete remission following biopsy, topical corticosteroids, and surgical excision. We also review all literature‐reported cases of pediatric PCSM‐TCLPD, emphasizing the disorder's benign nature and treatment responsiveness in children.