Chapter 15 – Acromegaly

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[7]  M. Gadelha,et al.  Lanreotide Autogel 120 mg at extended dosing intervals in patients with acromegaly biochemically controlled with octreotide LAR: the LEAD study , 2015, European journal of endocrinology.

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[9]  Zhezhen Jin,et al.  IGF-1 levels across the spectrum of normal to elevated in acromegaly: relationship to insulin sensitivity, markers of cardiovascular risk and body composition , 2015, Pituitary.

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[11]  M. Bronstein,et al.  Clomiphene citrate for treatment of acromegaly not controlled by conventional therapies. , 2015, The Journal of clinical endocrinology and metabolism.

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[18]  J. Lupski,et al.  Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation. , 2014, The New England journal of medicine.

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[26]  M. Korbonits,et al.  Effects of long-term growth hormone replacement in adults with growth hormone deficiency following cure of acromegaly: a KIMS analysis. , 2014, The Journal of clinical endocrinology and metabolism.

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[30]  R. Mamluk,et al.  A Novel Suspension Formulation Enhances Intestinal Absorption of Macromolecules Via Transient and Reversible Transport Mechanisms , 2014, Pharmaceutical Research.

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[39]  M. Fleseriu Insight into cardiovascular risk factors in patients with acromegaly , 2014, Endocrine.

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[47]  S. Gultekin,et al.  Growth hormone granulation pattern and somatostatin receptor subtype 2A correlate with postoperative somatostatin receptor ligand response in acromegaly: a large single center experience , 2013, Pituitary.

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[50]  Nicholas F. Marko,et al.  Comparative effectiveness review of treatment options for pituitary microadenomas in acromegaly. , 2012, Journal of neurosurgery.

[51]  J. Ramm-Pettersen,et al.  Intensity of pituitary adenoma on T2‐weighted magnetic resonance imaging predicts the response to octreotide treatment in newly diagnosed acromegaly , 2012, Clinical endocrinology.

[52]  A. Vortmeyer,et al.  Somatic GNAS Mutation Causes Widespread and Diffuse Pituitary Disease in Acromegalic Patients with McCune-Albright Syndrome , 2012, The Journal of clinical endocrinology and metabolism.

[53]  Eun Jig Lee,et al.  Predicting long-term remission by measuring immediate postoperative growth hormone levels and oral glucose tolerance test in acromegaly. , 2012, Neurosurgery.

[54]  V. Torri,et al.  Meta-Analysis on the Effects of Octreotide on Tumor Mass in Acromegaly , 2012, PloS one.

[55]  Tzulip Phang,et al.  Clinical implications of growth hormone–secreting tumor subtypes , 2012, Endocrine.

[56]  J. Ayuk Does pituitary radiotherapy increase the risk of stroke and, if so, what preventative actions should be taken? , 2012, Clinical endocrinology.

[57]  M. Buchfelder,et al.  Long-term safety of pegvisomant in patients with acromegaly: comprehensive review of 1288 subjects in ACROSTUDY. , 2012, The Journal of clinical endocrinology and metabolism.

[58]  P. Chanson,et al.  Germline AIP mutations in apparently sporadic pituitary adenomas: prevalence in a prospective single-center cohort of 443 patients. , 2012, The Journal of clinical endocrinology and metabolism.

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[62]  M. Gadelha,et al.  Aortic root ectasia in patients with acromegaly: experience at a single center , 2011, Clinical endocrinology.

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[96]  J. Romijn,et al.  High prevalence of arthropathy, according to the definitions of radiological and clinical osteoarthritis, in patients with long-term cure of acromegaly: a case-control study. , 2009, European journal of endocrinology.

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[100]  M. Bidlingmaier Problems with GH assays and strategies toward standardization. , 2008, European journal of endocrinology.

[101]  K. Kovacs,et al.  p21Cip1 restrains pituitary tumor growth , 2008, Proceedings of the National Academy of Sciences.

[102]  M. Davi’,et al.  Sleep apnoea syndrome is highly prevalent in acromegaly and only partially reversible after biochemical control of the disease. , 2008, European journal of endocrinology.

[103]  G. Vargas,et al.  Clinical and biochemical impact of the d3 growth hormone receptor genotype in acromegaly. , 2008, The Journal of clinical endocrinology and metabolism.

[104]  S. Melmed,et al.  Lipodystrophy in patients with acromegaly receiving pegvisomant. , 2008, The Journal of clinical endocrinology and metabolism.

[105]  G. Gamble,et al.  A meta-analysis of the effect of lowering serum levels of GH and IGF-I on mortality in acromegaly. , 2008, European journal of endocrinology.

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[108]  J. Hald,et al.  Preoperative octreotide treatment in newly diagnosed acromegalic patients with macroadenomas increases cure short-term postoperative rates: a prospective, randomized trial. , 2008, The Journal of clinical endocrinology and metabolism.

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[112]  P. Chanson,et al.  Epithelial sodium channel is a key mediator of growth hormone-induced sodium retention in acromegaly. , 2008, Endocrinology.

[113]  Hang Lee,et al.  Changing patterns in diagnosis and therapy of acromegaly over two decades. , 2008, The Journal of clinical endocrinology and metabolism.

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[117]  J. Hald,et al.  The clinical response to somatostatin analogues in acromegaly correlates to the somatostatin receptor subtype 2a protein expression of the adenoma , 2008, Clinical endocrinology.

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[127]  A. Parodi,et al.  Evidence of prolonged orocecal transit time and small intestinal bacterial overgrowth in acromegalic patients. , 2007, The Journal of clinical endocrinology and metabolism.

[128]  A. Umpleby,et al.  Protein metabolism in acromegaly: differential effects of short- and long-term treatment. , 2007, The Journal of clinical endocrinology and metabolism.

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[149]  P. Chanson,et al.  A critical analysis of pituitary tumor shrinkage during primary medical therapy in acromegaly. , 2005, The Journal of clinical endocrinology and metabolism.

[150]  Kolja A. Wawrowsky,et al.  Somatostatin Receptor Type 5 Modulates Somatostatin Receptor Type 2 Regulation of Adrenocorticotropin Secretion* , 2005, Journal of Biological Chemistry.

[151]  A. Barkan,et al.  Clinically silent somatotropinomas may be biochemically active. , 2005, The Journal of clinical endocrinology and metabolism.

[152]  D. Leroith,et al.  Intact insulin and insulin-like growth factor-I receptor signaling is required for growth hormone effects on skeletal muscle growth and function in vivo. , 2005, Endocrinology.

[153]  D. Rubello,et al.  Somatostatin analogs in vitro effects in a growth hormone-releasing hormone-secreting bronchial carcinoid. , 2005, The Journal of clinical endocrinology and metabolism.

[154]  J. Bevan Clinical review: The antitumoral effects of somatostatin analog therapy in acromegaly. , 2005, The Journal of clinical endocrinology and metabolism.

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[160]  R. Clayton,et al.  Growth hormone and pituitary radiotherapy, but not serum insulin-like growth factor-I concentrations, predict excess mortality in patients with acromegaly. , 2004, The Journal of clinical endocrinology and metabolism.

[161]  G. Gamble,et al.  Factors influencing mortality in acromegaly. , 2004, The Journal of clinical endocrinology and metabolism.

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[163]  M. Fischler,et al.  Using the Intubating Laryngeal Mask Airway for Ventilation and Endotracheal Intubation in Anesthetized and Unparalyzed Acromegalic Patients , 2004, Journal of neurosurgical anesthesiology.

[164]  M. Korbonits,et al.  Ghrelin exerts a proliferative effect on a rat pituitary somatotroph cell line via the mitogen-activated protein kinase pathway. , 2002, European journal of endocrinology.

[165]  Jeroen J. Bax,et al.  Increased prevalence of regurgitant valvular heart disease in acromegaly. , 2004, The Journal of clinical endocrinology and metabolism.

[166]  J. Bruce,et al.  Basal and Glucose-Suppressed GH Levels Less Than 1 μg/L in Newly Diagnosed Acromegaly , 2004, Pituitary.

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