Tick sialostatins L and L2 differentially influence dendritic cell responses to Borrelia spirochetes

[1]  J. Kopecký,et al.  Tick salivary cystatin sialostatin L2 suppresses IFN responses in mouse dendritic cells , 2015, Parasite immunology.

[2]  J. Andersen,et al.  The Tick Salivary Protein Sialostatin L2 Inhibits Caspase-1-Mediated Inflammation during Anaplasma phagocytophilum Infection , 2014, Infection and Immunity.

[3]  T. Geijtenbeek,et al.  Ménage à trois: Borrelia, dendritic cells, and tick saliva interactions. , 2014, Trends in parasitology.

[4]  R. M. Wooten,et al.  Borrelia burgdorferi Elicited-IL-10 Suppresses the Production of Inflammatory Mediators, Phagocytosis, and Expression of Co-Stimulatory Receptors by Murine Macrophages and/or Dendritic Cells , 2013, PloS one.

[5]  S. Han,et al.  Lipoteichoic acid of Enterococcus faecalis induces the expression of chemokines via TLR2 and PAFR signaling pathways , 2013, Journal of leukocyte biology.

[6]  Yue Chen,et al.  Modulation of dendritic cell function and immune response by cysteine protease inhibitor from murine nematode parasite Heligmosomoides polygyrus , 2013, Immunology.

[7]  Xin Li,et al.  TRIF Mediates Toll-Like Receptor 2-Dependent Inflammatory Responses to Borrelia burgdorferi , 2012, Infection and Immunity.

[8]  J. Kopecký,et al.  Effect of tick saliva on signalling pathways activated by TLR‐2 ligand and Borrelia afzelii in dendritic cells , 2012, Parasite immunology.

[9]  J. Kopecký,et al.  Effect of tick saliva on immune interactions between Borrelia afzelii and murine dendritic cells , 2011, Parasite immunology.

[10]  N. Boulanger,et al.  Tick saliva represses innate immunity and cutaneous inflammation in a murine model of Lyme disease. , 2011, Vector borne and zoonotic diseases.

[11]  D. Kaushal,et al.  Interleukin-10 Alters Effector Functions of Multiple Genes Induced by Borrelia burgdorferi in Macrophages To Regulate Lyme Disease Inflammation , 2011, Infection and Immunity.

[12]  Sarah E. Ewald,et al.  Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase , 2011, The Journal of experimental medicine.

[13]  J. Huber,et al.  Regulation of effector and memory T‐cell functions by type I interferon , 2011, Immunology.

[14]  B. Williams,et al.  Faculty Opinions recommendation of Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-beta. , 2011 .

[15]  B. Sahay,et al.  Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-β , 2011, Proceedings of the National Academy of Sciences.

[16]  J. Andersen,et al.  The crystal structures of two salivary cystatins from the tick Ixodes scapularis and the effect of these inhibitors on the establishment of Borrelia burgdorferi infection in a murine model , 2010, Molecular microbiology.

[17]  M. Oosting,et al.  Activation of innate host defense mechanisms by Borrelia. , 2010, European cytokine network.

[18]  I. Schwartz,et al.  Recognition of Borrelia burgdorferi, the Lyme Disease Spirochete, by TLR7 and TLR9 Induces a Type I IFN Response by Human Immune Cells1 , 2009, The Journal of Immunology.

[19]  S. Akira,et al.  Downstream Signals for MyD88-Mediated Phagocytosis of Borrelia burgdorferi Can Be Initiated by TRIF and Are Dependent on PI3K1 , 2009, The Journal of Immunology.

[20]  J. Andersen,et al.  The Immunomodulatory Action of Sialostatin L on Dendritic Cells Reveals Its Potential to Interfere with Autoimmunity1 , 2009, The Journal of Immunology.

[21]  J. Shupe,et al.  Activation of Human Monocytes by Live Borrelia burgdorferi Generates TLR2-Dependent and -Independent Responses Which Include Induction of IFN-β , 2009, PLoS pathogens.

[22]  Isabel M. Santos,et al.  The role of saliva in tick feeding. , 2009, Frontiers in bioscience.

[23]  J. Andersen,et al.  Cutting Edge: Immunity against a “Silent” Salivary Antigen of the Lyme Vector Ixodes scapularis Impairs Its Ability to Feed1 , 2008, The Journal of Immunology.

[24]  J. Kopecký,et al.  Tick Saliva Inhibits Dendritic Cell Migration, Maturation, and Function while Promoting Development of Th2 Responses1 , 2008, The Journal of Immunology.

[25]  A. Valledor,et al.  Selective Roles of MAPKs during the Macrophage Response to IFN-γ1 , 2008, The Journal of Immunology.

[26]  S. Akira,et al.  Distinct Roles for MyD88 and Toll-Like Receptors 2, 5, and 9 in Phagocytosis of Borrelia burgdorferi and Cytokine Induction , 2008, Infection and Immunity.

[27]  T. van der Poll,et al.  Salp15 Binding to DC-SIGN Inhibits Cytokine Expression by Impairing both Nucleosome Remodeling and mRNA Stabilization , 2008, PLoS pathogens.

[28]  H. Mühl,et al.  Systematic analysis highlights the key role of TLR2/NF-kappaB/MAP kinase signaling for IL-8 induction by macrophage-like THP-1 cells under influence of Borrelia burgdorferi lysates. , 2008, The international journal of biochemistry & cell biology.

[29]  J. Kopecký,et al.  Co-inoculation ofBorrelia afzelii with tick salivary gland extract influences distribution of immunocompetent cells in the skin and lymph nodes of mice , 2008, Folia Microbiologica.

[30]  J. Andersen,et al.  Selective Cysteine Protease Inhibition Contributes to Blood-feeding Success of the Tick Ixodes scapularis* , 2007, Journal of Biological Chemistry.

[31]  R. Bronson,et al.  Role of novel protein kinase C isoforms in Lyme arthritis , 2007, Cellular microbiology.

[32]  B. Osborne,et al.  c-Jun N-Terminal Kinase 1 Is Required for Toll-Like Receptor 1 Gene Expression in Macrophages , 2007, Infection and Immunity.

[33]  J. Andersen,et al.  133 Prostaglandin E2 is a Major Inhibitor of Dendritic Cell Maturation and Function in Ixodes Scapularis Saliva , 2007 .

[34]  J. Andersen,et al.  Antiinflammatory and Immunosuppressive Activity of Sialostatin L, a Salivary Cystatin from the Tick Ixodes scapularis* , 2006, Journal of Biological Chemistry.

[35]  S. Akira,et al.  MyD88 Deficiency Results in Tissue-Specific Changes in Cytokine Induction and Inflammation in Interleukin-18-Independent Mice Infected with Borrelia burgdorferi , 2006, Infection and Immunity.

[36]  A. Carlsson,et al.  Innate immune responses in Lyme borreliosis: enhanced tumour necrosis factor‐α and interleukin‐12 in asymptomatic individuals in response to live spirochetes , 2005, Clinical and experimental immunology.

[37]  Christophe Caux,et al.  A type I interferon autocrine–paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells , 2005, The Journal of experimental medicine.

[38]  J. Aliberti,et al.  Tick saliva inhibits differentiation, maturation and function of murine bone‐marrow‐derived dendritic cells , 2005, Immunology.

[39]  G. Trinchieri,et al.  Plasmacytoid dendritic cells in immunity , 2004, Nature Immunology.

[40]  S. Akira,et al.  MyD88 Plays a Unique Role in Host Defense but Not Arthritis Development in Lyme Disease1 , 2004, The Journal of Immunology.

[41]  Ruth R. Montgomery,et al.  Myeloid Differentiation Antigen 88 Deficiency Impairs Pathogen Clearance but Does Not Alter Inflammation in Borrelia burgdorferi-Infected Mice , 2004, Infection and Immunity.

[42]  Linden T. Hu,et al.  Borrelia burgdorferi-Induced Expression of Matrix Metalloproteinases from Human Chondrocytes Requires Mitogen-Activated Protein Kinase and Janus Kinase/Signal Transducer and Activator of Transcription Signaling Pathways , 2004, Infection and Immunity.

[43]  H. Young,et al.  Virally stimulated plasmacytoid dendritic cells produce chemokines and induce migration of T and NK cells , 2004, Journal of leukocyte biology.

[44]  S. Akira,et al.  Regulation of dendritic cell function through toll-like receptors. , 2003, Current molecular medicine.

[45]  S. Akira,et al.  Selective contribution of IFN-α/β signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[46]  S. Akira,et al.  Toll‐like receptor expression in murine DC subsets: lack of TLR7 expression by CD8α+ DC correlates with unresponsiveness to imidazoquinolines , 2003, European journal of immunology.

[47]  S. Akira,et al.  Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection. , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[48]  E. Fikrig,et al.  Murine Lyme Arthritis Development Mediated by p38 Mitogen-Activated Protein Kinase Activity1 , 2002, The Journal of Immunology.

[49]  Ion Gresser,et al.  Type I interferons produced by dendritic cells promote their phenotypic and functional activation. , 2002, Blood.

[50]  Marc Dalod,et al.  Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology , 2001, Nature Immunology.

[51]  F. Re,et al.  Toll-like Receptor 2 (TLR2) and TLR4 Differentially Activate Human Dendritic Cells* , 2001, The Journal of Biological Chemistry.

[52]  C. Maliszewski,et al.  Generation of murine dendritic cells from flt3-ligand-supplemented bone marrow cultures. , 2000, Blood.

[53]  J. A. Lopez,et al.  The role of dendritic cells in the innate immune system. , 2000, Microbes and infection.

[54]  R. M. Wooten,et al.  Cutting edge: inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2. , 1999, Journal of immunology.

[55]  B. Pulendran,et al.  Distinct dendritic cell subsets differentially regulate the class of immune response in vivo. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[56]  G. Schuler,et al.  An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. , 1999, Journal of immunological methods.

[57]  G. Stark,et al.  Regulation of STAT‐dependent pathways by growth factors and cytokines , 1996, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[58]  H. Ploegh,et al.  Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading. , 1996, Immunity.

[59]  D. Fish,et al.  Suppression of Acute Ixodes scapularis-Induced Borrelia burgdorferi Infection using Tumor Necrosis Factor-α, Interleukin-2, and Interferon-γ , 1996 .

[60]  D. Fish,et al.  Suppression of acute Ixodes scapularis-induced Borrelia burgdorferi infection using tumor necrosis factor-alpha, interleukin-2, and interferon-gamma. , 1996, The Journal of infectious diseases.