Loss of &bgr;-Catenin Promotes Chondrogenic Differentiation of Aortic Valve Interstitial Cells
暂无分享,去创建一个
[1] D. Chan,et al. The chondrocytic journey in endochondral bone growth and skeletal dysplasia. , 2014, Birth defects research. Part C, Embryo today : reviews.
[2] J. Defraigne,et al. Emerging pathogenic mechanisms in human myxomatous mitral valve: lessons from past and novel data. , 2013, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.
[3] R. Norris,et al. Mef2c Regulates Transcription of the Extracellular Matrix Protein Cartilage Link Protein 1 in the Developing Murine Heart , 2013, PloS one.
[4] J. Ni,et al. Comparison of the biological response of osteoblasts after tension and compression. , 2013, European journal of orthodontics.
[5] E. Ortona,et al. Human Myxomatous Mitral Valves Exhibit Focal Expression of Cartilage-related Proteins , 2013 .
[6] C. Semsarian,et al. Genetic Basis of Familial Valvular Heart Disease , 2012, Circulation. Cardiovascular genetics.
[7] J. Bavaria,et al. Human myxomatous mitral valve prolapse: Role of bone morphogenetic protein 4 in valvular interstitial cell activation , 2012, Journal of cellular physiology.
[8] V. Lefebvre,et al. Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytes. , 2012, Developmental cell.
[9] C. Lacerda,et al. Signaling pathways in mitral valve degeneration. , 2012, Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology.
[10] K. Yutzey,et al. Differential activation of valvulogenic, chondrogenic, and osteogenic pathways in mouse models of myxomatous and calcific aortic valve disease. , 2012, Journal of molecular and cellular cardiology.
[11] V. Castronovo,et al. Metallothionein-dependent up-regulation of TGF-β2 participates in the remodelling of the myxomatous mitral valve. , 2012, Cardiovascular research.
[12] T. Guy,et al. Mitral valve prolapse. , 2012, Annual review of medicine.
[13] D. Chan,et al. SOX9 Governs Differentiation Stage-Specific Gene Expression in Growth Plate Chondrocytes via Direct Concomitant Transactivation and Repression , 2011, PLoS genetics.
[14] J. Lincoln,et al. Sox9 Transcriptionally Represses Spp1 to Prevent Matrix Mineralization in Maturing Heart Valves and Chondrocytes , 2011, PloS one.
[15] K. J. Grande-Allen,et al. Calcific Aortic Valve Disease : Not Simply a Degenerative Process A Review and Agenda for Research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group , 2012 .
[16] V. Lefebvre,et al. Unraveling the transcriptional regulatory machinery in chondrogenesis , 2011, Journal of Bone and Mineral Metabolism.
[17] A. Gotlieb,et al. The response to valve injury. A paradigm to understand the pathogenesis of heart valve disease. , 2011, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.
[18] Takashi Nakamura,et al. Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways , 2011, Development.
[19] R. Hinton,et al. Differential expression of cartilage and bone-related proteins in pediatric and adult diseased aortic valves. , 2011, Journal of molecular and cellular cardiology.
[20] R. Hinton,et al. Heart valve structure and function in development and disease. , 2011, Annual review of physiology.
[21] R. Hinton,et al. Twist1 promotes heart valve cell proliferation and extracellular matrix gene expression during development in vivo and is expressed in human diseased aortic valves. , 2010, Developmental biology.
[22] J. Lincoln,et al. Reduced Sox9 Function Promotes Heart Valve Calcification Phenotypes In Vivo , 2010, Circulation Research.
[23] Santanu Chakraborty,et al. Wnt signaling in heart valve development and osteogenic gene induction. , 2010, Developmental biology.
[24] Marc W. Kirschner,et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling , 2009, Nature.
[25] K. Yutzey,et al. Heart Valve Development: Regulatory Networks in Development and Disease , 2009, Circulation research.
[26] A. Lassar,et al. The Transcriptional Activity of Sox9 in Chondrocytes Is Regulated by RhoA Signaling and Actin Polymerization , 2009, Molecular and Cellular Biology.
[27] K. Kadler,et al. Temporal and spatial expression of collagens during murine atrioventricular heart valve development and maintenance , 2008, Developmental dynamics : an official publication of the American Association of Anatomists.
[28] M. Taketo,et al. Stabilization of beta-catenin in XY gonads causes male-to-female sex-reversal. , 2008, Human molecular genetics.
[29] J. Bischoff,et al. Opposing actions of Notch1 and VEGF in post-natal cardiac valve endothelial cells. , 2008, Biochemical and biophysical research communications.
[30] Walter Birchmeier,et al. Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. , 2008, Genes & development.
[31] R. Hinton,et al. Mouse heart valve structure and function: echocardiographic and morphometric analyses from the fetus through the aged adult. , 2008, American journal of physiology. Heart and circulatory physiology.
[32] R. Markwald,et al. Periostin Is Required for Maturation and Extracellular Matrix Stabilization of Noncardiomyocyte Lineages of the Heart , 2008, Circulation research.
[33] Hongming Zhou,et al. Identification and characterization of a novel Schwann and outflow tract endocardial cushion lineage-restricted periostin enhancer. , 2007, Developmental biology.
[34] R. Kist,et al. Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development. , 2007, Developmental biology.
[35] J. Trochu,et al. Mutations in the Gene Encoding Filamin A as a Cause for Familial Cardiac Valvular Dystrophy , 2006, Circulation.
[36] Y. Kawakami,et al. The role of TGFβs and Sox9 during limb chondrogenesis , 2006 .
[37] K. Yutzey,et al. Hearts and bones: shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development. , 2006, Developmental biology.
[38] R. Bonow,et al. Human degenerative valve disease is associated with up-regulation of low-density lipoprotein receptor-related protein 5 receptor-mediated bone formation. , 2006, Journal of the American College of Cardiology.
[39] K. Yutzey,et al. BMP and FGF regulatory pathways control cell lineage diversification of heart valve precursor cells. , 2006, Developmental biology.
[40] J. I. Izpisúa Belmonte,et al. The role of TGFbetas and Sox9 during limb chondrogenesis. , 2006, Current opinion in cell biology.
[41] J. Marshall,et al. New Locus for Autosomal Dominant Mitral Valve Prolapse on Chromosome 13: Clinical Insights From Genetic Studies , 2005, Circulation.
[42] Xizhi Guo,et al. Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. , 2005, Developmental cell.
[43] Walter Birchmeier,et al. Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. , 2005, Developmental cell.
[44] F. Beier,et al. RhoA/ROCK Signaling Regulates Sox9 Expression and Actin Organization during Chondrogenesis* , 2005, Journal of Biological Chemistry.
[45] B. Griffin,et al. Mitral valve prolapse , 2005, The Lancet.
[46] S. Ikegawa,et al. SOX9-dependent and -independent Transcriptional Regulation of Human Cartilage Link Protein* , 2004, Journal of Biological Chemistry.
[47] E. Dejana,et al. -Catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouse , 2004 .
[48] P. McCrea,et al. Interactions between Sox9 and β-catenin control chondrocyte differentiation , 2004 .
[49] P. McCrea,et al. Interactions between Sox9 and beta-catenin control chondrocyte differentiation. , 2004, Genes & development.
[50] P. Greengard,et al. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor , 2004, Nature Medicine.
[51] E. Cuppen,et al. The Wnt/β-catenin pathway regulates cardiac valve formation , 2003, Nature.
[52] A. Bookout,et al. Quantitative real-time PCR protocol for analysis of nuclear receptor signaling pathways , 2003, Nuclear receptor signaling.
[53] Hans Clevers,et al. Negative Feedback Loop of Wnt Signaling through Upregulation of Conductin/Axin2 in Colorectal and Liver Tumors , 2002, Molecular and Cellular Biology.
[54] A. McMahon,et al. Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. , 2001, Development.
[55] Philippe Soriano. Generalized lacZ expression with the ROSA26 Cre reporter strain , 1999, Nature Genetics.
[56] Thomas D. Schmittgen,et al. Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2 2 DD C T Method , 2022 .