Differential requirements for IKKalpha and IKKbeta in the differentiation of primary human osteoarthritic chondrocytes.
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F. Flamigni | A. Facchini | K. Marcu | R. Borzì | M. Penzo | A. Facchini | E. Falcieri | S. Pagani | M. Battistelli | E. Olivotto | Xiang Li | Jun Li | Roberta Vitellozzi | R. Vitellozzi
[1] F. Flamigni,et al. Chondrocyte hypertrophy and apoptosis induced by GROα require three‐dimensional interaction with the extracellular matrix and a co‐receptor role of chondroitin sulfate and are associated with the mitochondrial splicing variant of cathepsin B , 2007, Journal of cellular physiology.
[2] Hana Kim,et al. A Fourth IκB Protein within the NF-κB Signaling Module , 2007, Cell.
[3] K. N. Pennington,et al. IκB Kinase Subunits α and γ Are Required for Activation of NF-κB and Induction of Apoptosis by Mammalian Reovirus , 2006, Journal of Virology.
[4] A. Hoffmann,et al. Transcriptional regulation via the NF-κB signaling module , 2006, Oncogene.
[5] A J Verbout,et al. Impact of expansion and redifferentiation conditions on chondrogenic capacity of cultured chondrocytes. , 2006, Tissue engineering.
[6] S. Jimenez,et al. NF-κB as a potential therapeutic target in osteoarthritis and rheumatoid arthritis , 2006 .
[7] Jian Fei Wang,et al. A Novel Role for GADD45β as a Mediator of MMP-13 Gene Expression during Chondrocyte Terminal Differentiation* , 2005, Journal of Biological Chemistry.
[8] Michael Karin,et al. NF-κB: linking inflammation and immunity to cancer development and progression , 2005, Nature Reviews Immunology.
[9] L. Pfeffer,et al. Interferon Induces NF-κB-inducing Kinase/Tumor Necrosis Factor Receptor-associated Factor-dependent NF-κB Activation to Promote Cell Survival* , 2005, Journal of Biological Chemistry.
[10] F. Flamigni,et al. Polyamine depletion inhibits NF‐κB binding to DNA and interleukin‐8 production in human chondrocytes stimulated by tumor necrosis factor‐α , 2005 .
[11] R. Borzì,et al. Cell and matrix morpho‐functional analysis in chondrocyte micromasses , 2005, Microscopy research and technique.
[12] B Kurz,et al. Oxygen and reactive oxygen species in cartilage degradation: friends or foes? , 2005, Osteoarthritis and cartilage.
[13] R. O’Keefe,et al. Transcriptional regulation of chondrocyte maturation: potential involvement of transcription factors in OA pathogenesis. , 2005, Molecular aspects of medicine.
[14] R. Zimmer,et al. Functional Genomics of Osteoarthritis: On the Way to Evaluate Disease Hypotheses , 2004, Clinical orthopaedics and related research.
[15] R. Spencer,et al. Hyaline cartilage engineered by chondrocytes in pellet culture: histological, immunohistochemical and ultrastructural analysis in comparison with cartilage explants , 2004, Journal of anatomy.
[16] H. Anderson,et al. Primary culture of rat growth plate chondrocytes: an in vitro model of growth plate histotype, matrix vesicle biogenesis and mineralization. , 2004, Bone.
[17] M. Karin,et al. The two NF-κB activation pathways and their role in innate and adaptive immunity , 2004 .
[18] M. Karin,et al. IκB kinase-α acts in the epidermis to control skeletal and craniofacial morphogenesis , 2004, Nature.
[19] Z. Werb,et al. Matrix remodeling during endochondral ossification. , 2004, Trends in cell biology.
[20] A. Baldwin,et al. NF-κB mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism , 2003 .
[21] Di Chen,et al. NF-κB Specifically Activates BMP-2 Gene Expression in Growth Plate Chondrocytes in Vivo and in a Chondrocyte Cell Line in Vitro* , 2003, Journal of Biological Chemistry.
[22] W. Li,et al. Induction of matrix metalloproteinase-13 gene expression by TNF-α is mediated by MAP kinases, AP-1, and NF-κB transcription factors in articular chondrocytes , 2003 .
[23] Brian D. Strahl,et al. A nucleosomal function for IκB kinase-α in NF-κB-dependent gene expression , 2003, Nature.
[24] R. Gaynor,et al. Histone H3 phosphorylation by IKK-α is critical for cytokine-induced gene expression , 2003, Nature.
[25] A. Lindahl,et al. Phenotypic Plasticity of Human Articular Chondrocytes , 2003, The Journal of bone and joint surgery. American volume.
[26] G. W. Peet,et al. IKKα, IKKβ, and NEMO/IKKγ Are Each Required for the NF-κB-mediated Inflammatory Response Program* , 2002, The Journal of Biological Chemistry.
[27] A. Zien,et al. Functional genomics of osteoarthritis. , 2002, Pharmacogenomics.
[28] R. Bernards,et al. Stable suppression of tumorigenicity by virus-mediated RNA interference. , 2002, Cancer cell.
[29] K. Ostergaard,et al. Histochemical studies of the extracellular matrix of human articular cartilage--a review. , 2002, Osteoarthritis and cartilage.
[30] E. Schmidt,et al. IKKα Provides an Essential Link between RANK Signaling and Cyclin D1 Expression during Mammary Gland Development , 2001, Cell.
[31] C. Brinckerhoff,et al. Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors , 2001, Arthritis Research & Therapy.
[32] T. Tuschl,et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells , 2001, Nature.
[33] Thomas Aigner,et al. Articular cartilage and changes in Arthritis: Cell biology of osteoarthritis , 2001, Arthritis Research & Therapy.
[34] R. Santerre,et al. Semi-Quantitative Fluorescence Analysis of Calcein Binding as a Measurement of In Vitro Mineralization , 2000, Calcified Tissue International.
[35] B. Swoboda,et al. Activation of annexin II and V expression, terminal differentiation, mineralization and apoptosis in human osteoarthritic cartilage. , 2000, Osteoarthritis and cartilage.
[36] C. Brinckerhoff,et al. Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3. , 2000, Arthritis and rheumatism.
[37] V. Lefebvre,et al. Potent Inhibition of the Master Chondrogenic FactorSox9 Gene by Interleukin-1 and Tumor Necrosis Factor-α* , 2000, The Journal of Biological Chemistry.
[38] A. Hollander,et al. Expression of Type X Collagen and Matrix Calcification in Three‐Dimensional Cultures of Immortalized Temperature‐Sensitive Chondrocytes Derived from Adult Human Articular Cartilage , 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[39] C. Snapper,et al. Nuclear Factor (NF)-κB2 (p100/p52) Is Required for Normal Splenic Microarchitecture and B Cell–mediated Immune Responses , 1998, The Journal of experimental medicine.
[40] P. Roughley,et al. Aggrecan degradation in human intervertebral disc and articular cartilage. , 1997, The Biochemical journal.
[41] C. Rorabeck,et al. Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage. , 1997, The Journal of clinical investigation.
[42] Q. Chen,et al. Progression and recapitulation of the chondrocyte differentiation program: cartilage matrix protein is a marker for cartilage maturation. , 1995, Developmental Biology.
[43] T. Aigner,et al. Osteogenic differentiation of hypertrophic chondrocytes involves asymmetric cell divisions and apoptosis , 1995, The Journal of cell biology.
[44] W. Landis,et al. Gene expression and extracellular matrix ultrastructure of a mineralizing chondrocyte cell culture system , 1991, The Journal of cell biology.
[45] D. Buttle,et al. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. , 1986, Biochimica et biophysica acta.
[46] N. Perkins,et al. Integrating cell-signalling pathways with NF-κB and IKK function , 2007, Nature Reviews Molecular Cell Biology.
[47] M. Goldring,et al. The control of chondrogenesis , 2006, Journal of cellular biochemistry.
[48] Ying Li,et al. Retroviral transduction with SOX9 enhances re-expression of the chondrocyte phenotype in passaged osteoarthritic human articular chondrocytes. , 2005, Osteoarthritis and cartilage.
[49] Kozo Nakamura,et al. Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation , 2005, Journal of Bone and Mineral Metabolism.
[50] R. Borzì,et al. A role for chemokines in the induction of chondrocyte phenotype modulation. , 2004, Arthritis and rheumatism.
[51] M. Attur,et al. Osteoarthritis or osteoarthrosis: the definition of inflammation becomes a semantic issue in the genomic era of molecular medicine. , 2002, Osteoarthritis and cartilage.