Interaction of Chromium(III) Complex of Glycylphenylalanine with Ninhydrin in Aqueous and Cetyltrimethylammonium Bromide (CTAB) Micellar Media

Abstract In this paper, we are reporting the influence of cationic CTAB surfactant on the interaction of chromium(III) complex of glycylphenylalanine [Cr(III)-Gly-Phe]2+ with ninhydrin under varying experimental conditions. The reaction follows irreversible first-order reaction kinetics with respect to [complex] and fractional-order with respect to [ninhydrin]. With progressive increase in [CTAB], the rate constant (kΨ) for condensation of ninhydrin into [Cr(III)-Gly-Phe]2+ complex increased, reached a maximum value, and then decreased. The results are best accounted for by the distribution of substrate into micellar and aqueous pseudo-phases as well as combination of substrate molecules with surfactant molecule. On the basis of above results, template mechanism has been discussed.

[1]  Malik Abdul Rub,et al.  Interaction between dipeptide (glycyl-phenylalanine) and ninhydrin: role of CTAB and gemini (16-s-16, s=4, 5, 6) surfactant micelles. , 2014, Journal of colloid and interface science.

[2]  Dileep Kumar,et al.  Influence of cationic gemini and conventional CTAB on the interaction of [Cr(III)-Gly-Tyr]2+ complex with ninhydrin , 2013 .

[3]  Dileep Kumar,et al.  Effect of dicationic gemini surfactants 16–s‐16 (s = 4, 5, 6) on the ninhydrin‐dipeptide (glycyl‐tyrosine) reaction , 2012 .

[4]  Dileep Kumar,et al.  Micelle-catalyzed reaction between ninhydrin and nickel dipeptide complex [Ni(II)-Gly-Tyr]+. , 2012, Colloids and surfaces. B, Biointerfaces.

[5]  Kabir-ud-din,et al.  Micellar and Solvent Effects on the Rate of Reaction Between L-Tyrosine and Ninhydrin , 2010 .

[6]  Kabir-ud-din,et al.  Kinetics and mechanism of interaction of dipeptide (glycyl–glycine) with ninhydrin in aqueous micellar media , 2006 .

[7]  M. Friedman.  Applications of the ninhydrin reaction for analysis of amino acids, peptides, and proteins to agricultural and biomedical sciences. , 2004, Journal of agricultural and food chemistry.

[8]  Z. Khan,et al.  Micellar and salt effects on the rate of the condensation between ninhydrin and [Cr(his)(H2O)3]2+ , 2001 .

[9]  Khan,et al.  The Micelle-Induced Interaction between Ninhydrin and Tryptophan. , 1999, Journal of colloid and interface science.

[10]  Khan,et al.  Effect of Cationic Micelles on the Kinetics of Interaction of Ninhydrin with l-Leucine and l-Phenylalanine. , 1999, Journal of colloid and interface science.

[11]  Kabir-ud-din,et al.  MICELLAR EFFECTS ON THE RATES OF THE CONDENSATION REACTION BETWEEN COPPER(II)HISTIDINE COMPLEX AND NINHYDRIN , 1999 .

[12]  C. A. Bunton.  Reactivity in aqueous association colloids. Descriptive utility of the pseudophase model , 1997 .

[13]  E. Rodenas,et al.  Inhibiton effect of cationic micelles on the basic hydrolysis of aromatic esters , 1986 .

[14]  C. H. Walker.  The Hydrophobic Effect: Formation of Micelles and Biological Membranes , 1981 .

[15]  C. A. Bunton.  Reaction Kinetics in Aqueous Surfactant Solutions , 1979 .

[16]  L. Mandell,et al.  Protonation site of a sulfonamide and the stereochemistry of proton exchange , 1967 .

[17]  E. Snell,et al.  Differentiation of α-Amino-Acids and Amines by Non-Enzymatic Transamination on Paper Chromatograms , 1957, Nature.

[18]  C. Hanes,et al.  Quantitative chromatographic methods for the study of enzymic transpeptidation reactions. , 1955, Canadian journal of biochemistry and physiology.