A study on the impacts of preoperative maximum detrusor pressure on minimally invasive surgery effect on patients with benign prostatic hyperplasia.

BACKGROUND This study aims to investigate the impacts of preoperative maximum detrusor pressure (Pdet.max) on minimally invasive surgery effect on patients with benign prostatic hyperplasia. METHODS The clinical data of a total of 156 patients receiving minimally invasive surgery for benign prostatic hyperplasia in Hospital of Nanchang Institute of Medical Sciences from August 2014 to June 2017 were retrospectively reviewed and summarized. The patients were divided into three groups according to different Pdet.max in the urodynamic examination results before the surgery, namely, group A (Pdet.max <50 cmH2O), group B (50≤ Pdet.max <90 cmH2O) and group C (Pdet.max ≥90 cmH2O). The International Prostate Symptom Score (IPSS) and quality-of-life score (QOLS) were compared. RESULTS Compared with those in group A, the IPSS and QOLS of the patients in group B and group C at 1 month, 3 months and 12 months after the surgery were decreased notably (all p<0.05). Moreover, the IPSS and QOLS of the patients in group C were obviously lower than those in group B (all p<0.05). CONCLUSIONS The results indicated that as the preoperative Pdet.max was increased, the symptoms of the patients receiving minimally invasive surgery for benign prostatic hyperplasia were ameliorated more significantly, and the patients had higher quality of life. The preoperative Pdet.max can judge the treatment effect of minimally invasive surgery on the patients with benign prostatic hyperplasia and help to guide the patients' prognosis. The greater the preoperative Pdet.max is, the better the treatment effect of the patients after the surgery will be, and the higher the quality of life will be.

[1]  P. Dasgupta,et al.  An updated systematic review and statistical comparison of standardised mean outcomes for the use of botulinum toxin in the management of lower urinary tract disorders. , 2014, European urology.

[2]  N. Callewaert,et al.  Capillary electrophoresis of urinary prostate glycoproteins assists in the diagnosis of prostate cancer , 2014, Electrophoresis.

[3]  Seung-June Oh,et al.  Effect of holmium laser enucleation of prostate on overactive bladder symptoms and urodynamic parameters: a prospective study. , 2014, Urology.

[4]  L. Mynderse,et al.  Efficacy of holmium laser enucleation of the prostate in patients with non-neurogenic impaired bladder contractility: results of a prospective trial. , 2014, Urology.

[5]  R. Dmochowski,et al.  Detrusor underactivity and the underactive bladder: a new clinical entity? A review of current terminology, definitions, epidemiology, aetiology, and diagnosis. , 2014, European urology.

[6]  L. Liao,et al.  Detrusor botulinum toxin A injection significantly decreased urinary tract infection in patients with traumatic spinal cord injury , 2013, Spinal Cord.

[7]  P. Tang,et al.  Urodynamically diagnosed detrusor hypocontractility: should transurethral resection of the prostate be contraindicated? , 2012, International Urology and Nephrology.

[8]  D. Margel,et al.  Presence of detrusor muscle in bladder tumor specimens--predictors and effect on outcome as a measure of resection quality. , 2014, Urologic oncology.

[9]  S. Kaplan.  Re: Predictive value of resistive index, detrusor wall thickness and ultrasound estimated bladder weight regarding the outcome after transurethral prostatectomy for patients with lower urinary tract symptoms suggestive of benign prostatic obstruction. , 2013, The Journal of urology.