Continuous measurement of oxy- and deoxyhemoglobin of piglet brain by time-resolved spectroscopy

A three-wavelength time-resolved spectroscopy (TRS) system was introduced to quantify oxy- and deoxyhemoglobin of the living tissue continuously. When the system was applied to the piglet brain, a time course of the tissue oxygenation could be traced corresponding to artificial respiratory condition. It was observed that alternation of inhalation oxygen concentration (FiO2) caused a reasonable change in the saturation of oxygen, maintaining the total hemoglobin (110 μ M) constant.