Reconstituted blood reduces blood donor exposures in children undergoing craniofacial reconstruction surgery

Objective/Aims:  To assess the effect of prophylactic administration of fresh‐frozen plasma (FFP) in the form of reconstituted blood in children undergoing craniofacial reconstruction. The outcomes of interest included immediate postoperative coagulation laboratory test results, postoperative surgical drain output, and the number of unique blood donor exposures incurred.

[1]  V. H. Kazanjian REMEMBRANCE OF THINGS PAST. , 1965 .

[2]  F. Verdú,et al.  [Risks of blood transfusion]. , 1981, Actas urologicas espanolas.

[3]  C. Coté,et al.  Changes in serial platelet counts following massive blood transfusion in pediatric patients. , 1982, Anesthesiology.

[4]  D. Heimbach,et al.  Clotting factor levels and the risk of diffuse microvascular bleeding in the massively transfused patient , 1987, British journal of haematology.

[5]  J. Tinker,et al.  Coagulation Changes during Packed Red Cell Replacement of Major Blood Loss , 1988, Anesthesiology.

[6]  R. Kearney,et al.  Craniosynostosis: an assessment of blood loss and transfusion practices , 1989, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[7]  É. Arnaud,et al.  Blood loss during repair of craniosynostosis. , 1993, British journal of anaesthesia.

[8]  H. Lazarus,et al.  A prospective microbiologic surveillance program to detect and prevent the transfusion of bacterially contaminated platelets , 1993, Transfusion.

[9]  E. Vahtera,et al.  Hemostatic Factors and Replacement of Major Blood Loss with Plasma-Poor Red Cell Concentrates , 1995, Anesthesia and analgesia.

[10]  S. Weinstein,et al.  Packed Red Cells in Acute Blood Loss: Dilutional Coagulopathy as a Cause of Surgical Bleeding , 1995, Anesthesia and analgesia.

[11]  R. Dodd,et al.  A retrospective analysis of microbial contaminants in outdated random‐donor platelets from multiple sites , 1997, Transfusion.

[12]  S. Buntain,et al.  Massive Transfusion and Hyperkalaemic Cardiac Arrest in Craniofacial Surgery in a Child , 1999, Anaesthesia and intensive care.

[13]  S. Black,et al.  Blood loss and transfusion practice in the perioperative management of craniosynostosis repair. , 1999, Journal of neurosurgical anesthesiology.

[14]  S. Black,et al.  Incidence of Venous Air Embolism during Craniectomy for Craniosynostosis Repair , 2000, Anesthesiology.

[15]  Glyn Williams,et al.  Abnormal Coagulation during Pediatric Craniofacial Surgery , 2001, Pediatric Neurosurgery.

[16]  D. Ririe,et al.  Transfusion-related acute lung injury in an infant during craniofacial surgery. , 2005, Anesthesia and analgesia.

[17]  M. Mavili,et al.  Blood Loss and Transfusion Rates During Repair of Craniofacial Deformities , 2005, The Journal of craniofacial surgery.

[18]  B. Dörken,et al.  Intraoperative fresh-frozen plasma versus human albumin in craniofacial surgery − A pilot study comparing coagulation profiles in infants younger than 12 months , 2007, Thrombosis and Haemostasis.

[19]  R. Benjamin,et al.  Transfusion‐related acute lung injury surveillance (2003‐2005) and the potential impact of the selective use of plasma from male donors in the American Red Cross , 2007, Transfusion.

[20]  A. Peitzman,et al.  An FFP:PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion. , 2008, The Journal of trauma.

[21]  R. Marcus,et al.  Predictors of Blood Loss in Fronto-Orbital Advancement and Remodeling , 2009, The Journal of craniofacial surgery.

[22]  N. Soni,et al.  Ten years of hemovigilance reports of transfusion‐related acute lung injury in the United Kingdom and the impact of preferential use of male donor plasma , 2009, Transfusion.

[23]  S. Bartlett,et al.  Blood loss, replacement, and associated morbidity in infants and children undergoing craniofacial surgery , 2010, Paediatric anaesthesia.