Blockage of Notch1 signaling modulates the T‐helper (Th)1/Th2 cell balance in chronic hepatitis B patients

Aim:  Chronic hepatitis B virus (HBV) infection is thought to involve the imbalance of T‐helper (Th)1/Th2 cells. Many procedures found Notch signaling involved the proliferation and differentiation of T lymphocytes during development and peripheral functions. The aim of this study was to discover the effect of blockage of Notch1 signaling to Th cells and the mechanisms involved in chronic hepatitis B patients.

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