Acid–Base Physiology

[1]  Jesse M. Ehrenfeld,et al.  Balanced Crystalloids versus Saline in Critically Ill Adults , 2018, Journal Club AINS.

[2]  V. Koulouras,et al.  Metabolic acidosis during parenteral nutrition: Pathophysiological mechanisms , 2015, Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine.

[3]  F. Holstege,et al.  Aberrant Expression and Distribution of Enzymes of the Urea Cycle and Other Ammonia Metabolizing Pathways in Dogs with Congenital Portosystemic Shunts , 2014, PloS one.

[4]  R. Attridge,et al.  Intravenous Sodium Bicarbonate Therapy in Severely Acidotic Diabetic Ketoacidosis , 2013, The Annals of pharmacotherapy.

[5]  J. Kellum,et al.  Is there a difference between strong ion gap in healthy volunteers and intensive care unit patients? , 2010, Journal of critical care.

[6]  J. Kellum,et al.  Metabolic acidosis in patients with severe sepsis and septic shock: A longitudinal quantitative study , 2009, Critical care medicine.

[7]  T. Ring Mixing bicarbonates: dilution acidosis from first principles , 2009, Intensive Care Medicine.

[8]  B. Schneeweiss,et al.  A critique of Stewart’s approach: the chemical mechanism of dilutional acidosis , 2009, Intensive Care Medicine.

[9]  Christina W. Fidkowski,et al.  Diagnosing metabolic acidosis in the critically ill: bridging the anion gap, Stewart, and base excess methods , 2009, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[10]  F. Gennari,et al.  Acid-base disturbances in gastrointestinal disease. , 2008, Clinical journal of the American Society of Nephrology : CJASN.

[11]  M. Castro,et al.  Characterization of acid-base status in maintenance hemodialysis: physicochemical approach , 2008, Journal of Artificial Organs.

[12]  J. Kraut,et al.  Acid-base analysis: a critique of the Stewart and bicarbonate-centered approaches. , 2008, American journal of physiology. Renal physiology.

[13]  L. Kluijtmans,et al.  Contribution of various metabolites to the “unmeasured” anions in critically ill patients with metabolic acidosis* , 2008, Critical care medicine.

[14]  J. Kellum,et al.  COMPARISON OF ACID-BASE MODELS FOR PREDICTION OF HOSPITAL MORTALITY AFTER TRAUMA , 2007, Shock.

[15]  J. Kellum Disorders of acid-base balance , 2007, Critical care medicine.

[16]  L. Forni,et al.  Unmeasured anions in metabolic acidosis: unravelling the mystery , 2006, Critical care.

[17]  J. Kellum,et al.  Lactate versus non-lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients , 2006, Critical care.

[18]  L. Forni,et al.  Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis , 2005, Critical care.

[19]  S. Nielsen,et al.  Clinical review: Renal tubular acidosis – a physicochemical approach , 2005, Critical care.

[20]  K. Gunnerson Clinical review: The meaning of acid–base abnormalities in the intensive care unit part I – epidemiology , 2005, Critical care.

[21]  John A Kellum,et al.  Clinical review: Reunification of acid–base physiology , 2005, Critical care.

[22]  H. Belzberg,et al.  Diagnosis of acid-base derangements and mortality prediction in the trauma intensive care unit: the physiochemical approach. , 2005, The Journal of trauma.

[23]  H. Corey Bench-to-bedside review: Fundamental principles of acid-base physiology , 2004, Critical care.

[24]  E. W. Wooten Science review: Quantitative acid–base physiology using the Stewart model , 2004, Critical care.

[25]  G. Schmidt,et al.  Bench-to-bedside review: Treating acid–base abnormalities in the intensive care unit – the role of buffers , 2004, Critical care.

[26]  J. Kellum,et al.  Initial pH, base deficit, lactate, anion gap, strong ion difference, and strong ion gap predict outcome from major vascular injury* , 2004, Critical care medicine.

[27]  H. Corey Stewart and beyond: new models of acid-base balance. , 2003, Kidney international.

[28]  E. W. Wooten,et al.  Calculation of physiological acid-base parameters in multicompartment systems with application to human blood. , 2003, Journal of applied physiology.

[29]  Rinaldo Bellomo,et al.  Unmeasured anions in critically ill patients: Can they predict mortality?* , 2003, Critical care medicine.

[30]  S. Steele,et al.  Serum lactate and base deficit as predictors of mortality and morbidity. , 2003, American journal of surgery.

[31]  D. De Backer Lactic acidosis , 2003, Intensive Care Medicine.

[32]  A. Fraser Clinical Toxicologic Implications of Ethylene Glycol and Glycolic Acid Poisoning , 2002, Therapeutic drug monitoring.

[33]  R. Grounds,et al.  Acid−base physiology: the ‘traditional’ and the ‘modern’ approaches , 2002, Anaesthesia.

[34]  T. J. Morgan,et al.  Crystalloid strong ion difference determines metabolic acid-base change during in vitro hemodilution , 2002, Critical care medicine.

[35]  S. Mallett,et al.  The Effects of Balanced Versus Saline-Based Hetastarch and Crystalloid Solutions on Acid-Base and Electrolyte Status and Gastric Mucosal Perfusion in Elderly Surgical Patients , 2001, Anesthesia and analgesia.

[36]  J. Waters,et al.  Dilutional Acidosis following Hetastarch or Albumin in Healthy Volunteers , 2000, Anesthesiology.

[37]  D. Schoenfeld,et al.  Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. , 2000, The New England journal of medicine.

[38]  J. Kellum Determinants of blood pH in health and disease , 2000, Critical care.

[39]  S. Clack,et al.  Cause of metabolic acidosis in prolonged surgery. , 1999, Critical care medicine.

[40]  J. Severinghaus,et al.  Human PaCO2 and standard base excess compensation for acid-base imbalance. , 1998, Critical care medicine.

[41]  R. Bellomo,et al.  ETIOLOGY OF METABOLIC ACIDOSIS DURING SALINE RESUSCITATION IN ENDOTOXEMIA , 1998, Shock.

[42]  J. Uribarri,et al.  D‐Lactic Acidosis: A Review of Clinical Presentation, Biochemical Features, and Pathophysiologic Mechanisms , 1998, Medicine.

[43]  J. Vincent,et al.  Lactate production by the lungs in acute lung injury. , 1997, American journal of respiratory and critical care medicine.

[44]  R Bellomo,et al.  Release of lactate by the lung in acute lung injury. , 1997, Advances in experimental medicine and biology.

[45]  P. Nabet,et al.  Comparison of norepinephrine and dobutamine to epinephrine for hemodynamics, lactate metabolism, and gastric tonometric variables in septic shock: a prospective, randomized study , 1997, Intensive Care Medicine.

[46]  P. Stacpoole Lactic acidosis and other mitochondrial disorders. , 1997, Metabolism: clinical and experimental.

[47]  M. Fink Does tissue acidosis in sepsis indicate tissue hypoperfusion? , 1996, Intensive Care Medicine.

[48]  R. Bellomo,et al.  Transvisceral lactate fluxes during early endotoxemia. , 1996, Chest.

[49]  J. Hibbert,et al.  Lactic acidosis during sepsis is related to increased pyruvate production, not deficits in tissue oxygen availability. , 1996, Annals of surgery.

[50]  G. Gutierrez,et al.  Pulmonary lactate release in patients with sepsis and the adult respiratory distress syndrome. , 1996, Journal of critical care.

[51]  T. Scalea,et al.  Serum lactate is not predicted by anion gap or base excess after trauma resuscitation. , 1996, The Journal of trauma.

[52]  H. Sahebjami A New Range for the Anion Gap , 1995, Annals of Internal Medicine.

[53]  M. Wysocki,et al.  Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. , 1995, The New England journal of medicine.

[54]  R. Bellomo,et al.  Hepatic anion flux during acute endotoxemia. , 1995, Journal of applied physiology.

[55]  J. Kellum,et al.  Strong ion gap: a methodology for exploring unexplained anions. , 1995, Journal of critical care.

[56]  K. Hickling,et al.  Low mortality rate in adult respiratory distress syndrome using low-volume, pressure-limited ventilation with permissive hypercapnia: A prospective study , 1994 .

[57]  A. Froese,et al.  Ventilator pattern influences neutrophil influx and activation in atelectasis-prone rabbit lung. , 1994, Journal of applied physiology.

[58]  B. Gilfix,et al.  A physical chemical approach to the analysis of acid-base balance in the clinical setting. , 1993, Journal of critical care.

[59]  T. Scalea,et al.  Lactate clearance and survival following injury. , 1993, The Journal of trauma.

[60]  R. Nunnally,et al.  Carbicarb, sodium bicarbonate, and sodium chloride in hypoxic lactic acidosis. Effect on arterial blood gases, lactate concentrations, hemodynamic variables, and myocardial intracellular pH. , 1993, Chest.

[61]  R. Bersin,et al.  A Controlled Clinical Trial of Dichloroacetate for Treatment of Lactic Acidosis in Adults , 1992 .

[62]  J. Morris,et al.  Base deficit stratifies mortality and determines therapy. , 1992, The Journal of trauma.

[63]  S. Mujais,et al.  Gaps in the anion gap. , 1992, Archives of internal medicine.

[64]  J. Falk,et al.  Lactic acidosis in critical illness , 1992, Critical care medicine.

[65]  S. Cain,et al.  Systemic and regional oxygen uptake and delivery and lactate flux in endotoxic dogs infused with dopexamine , 1991, Critical care medicine.

[66]  M. Weil,et al.  Buffer solutions may compromise cardiac resuscitation by reducing coronary perfusion presssure. , 1991, JAMA.

[67]  L. Opie,et al.  Protons in ischemia: where do they come from; where do they go to? , 1991, Journal of molecular and cellular cardiology.

[68]  C. Slovis,et al.  The syndrome of alcoholic ketoacidosis. , 1991, The American journal of medicine.

[69]  C. Mecher,et al.  Unaccounted for anion in metabolic acidosis during severe sepsis in humans , 1991, Critical care medicine.

[70]  S. Aggarwal,et al.  Clinical Evaluation of Autotransfusion During Liver Transplantation , 1991, Anesthesia and analgesia.

[71]  N L Jones,et al.  A quantitative physicochemical approach to acid-base physiology. , 1990, Clinical biochemistry.

[72]  Bradley J. Hind man Sodium bicarbonate in the treatment of subtypes of acute lactic acidosis: physiologic considerations. , 1990 .

[73]  G. Brooks,et al.  Defining hypoxia: a systems view of VO2, glycolysis, energetics, and intracellular PO2. , 1990, Journal of applied physiology.

[74]  P. Gabow,et al.  The fall of the serum anion gap. , 1990, Archives of internal medicine.

[75]  D. Batlle,et al.  The use of the urinary anion gap in the diagnosis of hyperchloremic metabolic acidosis. , 1988, The New England journal of medicine.

[76]  B. Materson,et al.  Use of the Anion Gap in Clinical Medicine , 1988, Southern medical journal.

[77]  M. Haupt,et al.  The effect of fluid loading, blood transfusion, and catecholamine infusion on oxygen delivery and consumption in patients with sepsis. , 1986, The American review of respiratory disease.

[78]  R. Kushner Total parenteral nutrition-associated metabolic acidosis. , 1986, JPEN. Journal of parenteral and enteral nutrition.

[79]  R. Carlson,et al.  THE RELATIONSHIP BETWEEN ANION GAP AND ELEVATED LACTATE , 1986 .

[80]  A. Arieff,et al.  Evidence for a detrimental effect of bicarbonate therapy in hypoxic lactic acidosis. , 1985, Science.

[81]  P. Gabow Disorders associated with an altered anion gap. , 1985, Kidney international.

[82]  P A Stewart,et al.  Modern quantitative acid-base chemistry. , 1983, Canadian journal of physiology and pharmacology.

[83]  H. F. Woods,et al.  Lactic Acidosis Revisited , 1983, Diabetes.

[84]  M. Emmett Simple and Mixed Acid‐Base Disorders: A Practical Approach , 1980, Medicine.

[85]  R. Kreisberg Lactate homeostasis and lactic acidosis. , 1980, Annals of internal medicine.

[86]  B. Widmer,et al.  Serum electrolyte and acid base composition. The influence of graded degrees of chronic renal failure. , 1979, Archives of internal medicine.

[87]  W. Schwartz,et al.  Regulation of acid-base equilibrium in chronic hypocapnia. Evidence that the response of the kidney is not geared to the defense of extracellular (H+). , 1976, The Journal of clinical investigation.

[88]  S. I. Kahn,et al.  Dilution acidosis and contraction alkalosis: review of a concept. , 1975, Kidney international.

[89]  A. Tzamaloukas,et al.  Effect of isotonic volume expansion on extracellular bicarbonate stores in normal dogs. , 1973, The American journal of physiology.

[90]  A. Arieff,et al.  NONKETOTIC HYPEROSMOLAR COMA WITH HYPERGLYCEMIA: CLINICAL FEATURES, PATHOPHYSIOLOGY, RENAL FUNCTION, ACID-BASE BALANCE, PLASMA-CEREBROSPINAL FLUID EQUILIBRIA AND THE EFFECTS OF THERAPHY IN 37 CASES , 1972, Medicine.

[91]  W. G. Walker,et al.  Carbenicillin-induced acidosis and seizures. , 1971, JAMA.

[92]  E. Blair Acid-base balance in bacteremic shock. , 1971, Archives of internal medicine.

[93]  M H Weil,et al.  Experimental and Clinical Studies on Lactate and Pyruvate as Indicators of the Severity of Acute Circulatory Failure (Shock) , 1970, Circulation.

[94]  E. W. Moore,et al.  The alkaline tide. , 1967, Gastroenterology.

[95]  H. L. Bleich,et al.  Tris buffer (THAM). An appraisal of its physiologic effects and clinical usefulness. , 1966, The New England journal of medicine.

[96]  B. Billing,et al.  The effect of adrenaline and noradrenaline on hepatic blood flow and splanchnic carbohydrate metabolism in man , 1951, The Journal of physiology.

[97]  G. Trajano,et al.  Lactate, not Lactic Acid, is Produced by Cellular Cytosolic Energy Catabolism. , 2018, Physiology.

[98]  K. Walley,et al.  Lactic Acidosis in Sepsis: It's Not All Anaerobic: Implications for Diagnosis and Management. , 2016, Chest.

[99]  G. Gutierrez,et al.  Lactic acidosis in sepsis: a commentary , 2005, Intensive Care Medicine.

[100]  J. A. Vale,et al.  Does Urine Alkalinization Increase Salicylate Elimination? If so, Why? , 2003, Toxicological reviews.

[101]  G. Schmidt,et al.  Sodium bicarbonate for the treatment of lactic acidosis. , 2000, Chest.

[102]  A. Spital,et al.  Correction of acid-base derangements , 1998 .

[103]  J. Kellum,et al.  Biochemical and biophysical principles of hydrogen ion regulation , 1998 .

[104]  K. Walley,et al.  Impact of acid-base disorders on individual organ systems , 1998 .

[105]  S. Magder Pathophysiology of metabolic acid-base disturbances in patients with critical illness , 1998 .

[106]  L. Gattinoni,et al.  Pathophysiology and diagnosis of respiratory acid-base disturbances in patients with critical illness , 1998 .

[107]  N. Madias,et al.  Management of Life-Threatening AcidBase Disorders , 1998 .

[108]  R. Schlichtig,et al.  [Base Excess] vs [Strong ION Difference] , 1997 .

[109]  D. E. Atkinson,et al.  pH Homeostasis in Terrestrial Vertebrates; Ammonium Ion as a Proton Source , 1995 .

[110]  M. Fulop Alcoholic ketoacidosis. , 1993, Endocrinology and metabolism clinics of North America.

[111]  D. Häussinger,et al.  pH homeostasis: the conceptual change. , 1992, Contributions to nephrology.

[112]  M. Takeya,et al.  Histopathologic pulmonary changes from mechanical ventilation at high peak airway pressures. , 1991, The American review of respiratory disease.

[113]  L. Goldfrank,et al.  Assessment of acid-base disturbances in hypothermia and their physiologic consequences. , 1989, Annals of emergency medicine.

[114]  K. Alberti Diabetic emergencies. , 1989, British medical bulletin.

[115]  R. Bersin,et al.  Improved hemodynamic function during hypoxia with Carbicarb, a new agent for the management of acidosis. , 1988, Circulation.

[116]  N. E. Madias Lactic acidosis. , 1986, Kidney international.

[117]  G. T. Shires,et al.  Dilution acidosis. , 1948, Annals of internal medicine.