A self-inactivating invertebrate opsin with resistance to retinal depletion optically drives biased signaling toward Gβγ-dependent ion channel modulation
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[1] A. Terakita,et al. High-performance optical control of GPCR signaling by bistable animal opsins MosOpn3 and LamPP in a molecular property–dependent manner , 2022, Proceedings of the National Academy of Sciences of the United States of America.
[2] P. Hegemann,et al. WiChR, a highly potassium-selective channelrhodopsin for low-light one- and two-photon inhibition of excitable cells , 2022, Science advances.
[3] O. Yizhar,et al. Optogenetics at the presynapse , 2022, Nature Neuroscience.
[4] J. Simon Wiegert,et al. Aion is a bistable anion-conducting channelrhodopsin that provides temporally extended and reversible neuronal silencing , 2022, Communications Biology.
[5] T. Bruegmann,et al. Optogenetic Stimulation of Gi Signaling Enables Instantaneous Modulation of Cardiomyocyte Pacemaking , 2021, Frontiers in Physiology.
[6] Y. Kubo,et al. A novel ion conducting route besides the central pore in an inherited mutant of G-protein-gated inwardly rectifying K+ channel , 2021, bioRxiv.
[7] R. Sunahara,et al. A photoswitchable GPCR-based opsin for presynaptic inhibition , 2021, Neuron.
[8] J. Simon Wiegert,et al. Efficient optogenetic silencing of neurotransmitter release with a mosquito rhodopsin , 2021, Neuron.
[9] Elliot J. Gerrard,et al. Seasonal variation in UVA light drives hormonal and behavioral changes in a marine annelid via a ciliary opsin , 2021, Nature Ecology & Evolution.
[10] Franck P. Martial,et al. Using a bistable animal opsin for switchable and scalable optogenetic inhibition of neurons , 2020, bioRxiv.
[11] M. Mark,et al. Lamprey Parapinopsin (“UVLamP”): a Bistable UV‐Sensitive Optogenetic Switch for Ultrafast Control of GPCR Pathways , 2019, Chembiochem : a European journal of chemical biology.
[12] R. Lang,et al. Neuropsin (OPN5) Mediates Local Light-Dependent Induction of Circadian Clock Genes and Circadian Photoentrainment in Exposed Murine Skin , 2019, Current Biology.
[13] Naomi R. Latorraca,et al. human Neurotensin Receptor 1 (hNTSR1) - Gi1 Protein Complex in non-canonical conformation (NC state) , 2019 .
[14] R. Russell,et al. Illuminating G-Protein-Coupling Selectivity of GPCRs , 2019, Cell.
[15] T. Bruegmann,et al. Optogenetic stimulation of Gs-signaling in the heart with high spatio-temporal precision , 2019, Nature Communications.
[16] J. Williams,et al. Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects , 2019, Nature Communications.
[17] L. May,et al. Characterisation of endogenous A2A and A2B receptor-mediated cyclic AMP responses in HEK 293 cells using the GloSensor™ biosensor: Evidence for an allosteric mechanism of action for the A2B-selective antagonist PSB 603 , 2018, Biochemical pharmacology.
[18] J. Simon Wiegert,et al. Silencing Neurons: Tools, Applications, and Experimental Constraints , 2017, Neuron.
[19] Y. Kubo,et al. A ciliary opsin in the brain of a marine annelid zooplankton is ultraviolet-sensitive, and the sensitivity is tuned by a single amino acid residue , 2017, The Journal of Biological Chemistry.
[20] M. Bruchas,et al. Optogenetic approaches for dissecting neuromodulation and GPCR signaling in neural circuits. , 2017, Current opinion in pharmacology.
[21] B. Roth. DREADDs for Neuroscientists , 2016, Neuron.
[22] A. Terakita,et al. Activation of Transducin by Bistable Pigment Parapinopsin in the Pineal Organ of Lower Vertebrates , 2015, PloS one.
[23] Y. Kubo,et al. Retinal Attachment Instability Is Diversified among Mammalian Melanopsins* , 2015, The Journal of Biological Chemistry.
[24] Siegrid Löwel,et al. Restoring the ON Switch in Blind Retinas: Opto-mGluR6, a Next-Generation, Cell-Tailored Optogenetic Tool , 2015, PLoS biology.
[25] G. Nagel,et al. Channelrhodopsin-2–XXL, a powerful optogenetic tool for low-light applications , 2014, Proceedings of the National Academy of Sciences.
[26] Takashi Maejima,et al. Vertebrate Cone Opsins Enable Sustained and Highly Sensitive Rapid Control of Gi/o Signaling in Anxiety Circuitry , 2014, Neuron.
[27] Hisao Tsukamoto,et al. Homologs of vertebrate Opn3 potentially serve as a light sensor in nonphotoreceptive tissue , 2013, Proceedings of the National Academy of Sciences.
[28] Barry E Knox,et al. Rapid release of retinal from a cone visual pigment following photoactivation. , 2012, Biochemistry.
[29] A. Terakita,et al. Diversity and functional properties of bistable pigments , 2010, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.
[30] C. Lüscher,et al. Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease , 2010, Nature Reviews Neuroscience.
[31] Raag D. Airan,et al. Temporally precise in vivo control of intracellular signalling , 2009, Nature.
[32] H. Chiel,et al. Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[33] Z. Zuo,et al. The role of opioid receptor internalization and beta-arrestins in the development of opioid tolerance. , 2005, Anesthesia and analgesia.
[34] K. Hofmann,et al. Transition of Rhodopsin into the Active Metarhodopsin II State Opens a New Light-induced Pathway Linked to Schiff Base Isomerization* , 2004, Journal of Biological Chemistry.
[35] D. Arendt,et al. Ciliary Photoreceptors with a Vertebrate-Type Opsin in an Invertebrate Brain , 2004, Science.
[36] Y. Kubo,et al. Ser165 in the Second Transmembrane Region of the Kir2.1 Channel Determines its Susceptibility to Blockade by Intracellular Mg2+ , 2002, The Journal of general physiology.
[37] J. Hepler,et al. Cellular Regulation of RGS Proteins: Modulators and Integrators of G Protein Signaling , 2002, Pharmacological Reviews.
[38] F J Sigworth,et al. Two-microelectrode voltage clamp of Xenopus oocytes: voltage errors and compensation for local current flow. , 1999, Biophysical journal.
[39] Y. Shichida,et al. Visual pigment: G-protein-coupled receptor for light signals , 1998, Cellular and Molecular Life Sciences CMLS.
[40] Y. Kubo,et al. Structural basis for a Ca2+-sensing function of the metabotropic glutamate receptors. , 1998, Science.
[41] Y. Kubo,et al. RGS8 accelerates G-protein-mediated modulation of K+currents , 1997, Nature.
[42] H. Korf,et al. Rod-opsin immunoreaction in the pineal organ of the pigmented mouse does not indicate the presence of a functional photopigment , 1993, Cell and Tissue Research.
[43] A. Brown,et al. Rapid beta-adrenergic modulation of cardiac calcium channel currents by a fast G protein pathway. , 1989, Science.
[44] B. Sakmann,et al. Patch clamp measurements onXenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels , 1986, Pflügers Archiv.
[45] H. Lester,et al. A photoisomerizable muscarinic antagonist. Studies of binding and of conductance relaxations in frog heart , 1982, The Journal of general physiology.
[46] H. Tsukamoto,et al. Optogenetic Modulation of Ion Channels by Photoreceptive Proteins. , 2021, Advances in experimental medicine and biology.
[47] R. Foster,et al. Opsin-like immunoreaction in the retinae and pineal organs of four mammalian species , 2004, Cell and Tissue Research.
[48] J. Ruppersberg. Ion Channels in Excitable Membranes , 1996 .