RTX-Toxins

RTX-Toxins (Repeats in ToXin) are members of a rapidly expanding family of proteins [...].

[1]  R. Benz,et al.  Membrane Activity and Channel Formation of the Adenylate Cyclase Toxin (CyaA) of Bordetella pertussis in Lipid Bilayer Membranes , 2020, Toxins.

[2]  M. Ali,et al.  Calcium-Induced Activity and Folding of a Repeat in Toxin Lipase from Antarctic Pseudomonas fluorescens Strain AMS8 , 2020, Toxins.

[3]  R. Welch,et al.  RTX Toxins Ambush Immunity’s First Cellular Responders , 2019, Toxins.

[4]  J. Frey.  RTX Toxins of Animal Pathogens and Their Role as Antigens in Vaccines and Diagnostics , 2019, Toxins.

[5]  U. Baumann.  Structure–Function Relationships of the Repeat Domains of RTX Toxins , 2019, Toxins.

[6]  R. Benz,et al.  Channel Formation by LktA of Mannheimia (Pasteurella) haemolytica in Lipid Bilayer Membranes and Comparison of Channel Properties with Other RTX-Cytolysins , 2019, Toxins.

[7]  H. Schmidt,et al.  Genetics, Toxicity, and Distribution of Enterohemorrhagic Escherichia coli Hemolysin , 2019, Toxins.

[8]  S. Kachlany,et al.  Aggregatibacter actinomycetemcomitans Leukotoxin (LtxA; Leukothera®): Mechanisms of Action and Therapeutic Applications , 2019, Toxins.

[9]  D. Ladant,et al.  Post‐translational acylation controls the folding and functions of the CyaA RTX toxin , 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[10]  R. Osicka,et al.  Distinct Spatiotemporal Distribution of Bacterial Toxin-Produced Cellular cAMP Differentially Inhibits Opsonophagocytic Signaling , 2019, Toxins.

[11]  J. Mašín,et al.  Rapid Purification of Endotoxin-Free RTX Toxins , 2019, Toxins.

[12]  D. Ladant,et al.  The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro , 2019, Toxins.

[13]  D. Ladant,et al.  Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Antigen-Delivery and Immunotherapy , 2018, Toxins.

[14]  David González-Bullón,et al.  Phospholipase A activity of adenylate cyclase toxin mediates translocation of its adenylate cyclase domain , 2017, Proceedings of the National Academy of Sciences.

[15]  L. Schmitt,et al.  Type I Protein Secretion-Deceptively Simple yet with a Wide Range of Mechanistic Variability across the Family. , 2016, EcoSal Plus.

[16]  R. Benz.  Channel formation by RTX-toxins of pathogenic bacteria: Basis of their biological activity. , 2016, Biochimica et biophysica acta.

[17]  Julia Chamot-Rooke,et al.  Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion , 2015, Scientific Reports.

[18]  Karla J. F. Satchell.  Multifunctional-autoprocessing repeats-in-toxin (MARTX) Toxins of Vibrios , 2015, Microbiology spectrum.

[19]  Y. Moon,et al.  Identification of the minimal region in lipase ABC transporter recognition domain of Pseudomonas fluorescens for secretion and fluorescence of green fluorescent protein , 2012, Microbial Cell Factories.

[20]  I. Linhartova,et al.  RTX proteins: a highly diverse family secreted by a common mechanism , 2010, FEMS microbiology reviews.

[21]  R. Benz,et al.  Structural and Functional Characterization of an Essential RTX Subdomain of Bordetella pertussis Adenylate Cyclase Toxin* , 2006, Journal of Biological Chemistry.

[22]  R. Benz,et al.  Acylation of lysine 860 allows tight binding and cytotoxicity of Bordetella adenylate cyclase on CD11b-expressing cells. , 2005, Biochemistry.

[23]  R. Benz,et al.  Adenylate cyclase toxin (CyaA) of Bordetella pertussis. Evidence for the formation of small ion-permeable channels and comparison with HlyA of Escherichia coli. , 1994, The Journal of biological chemistry.

[24]  U. Baumann,et al.  Three‐dimensional structure of the alkaline protease of Pseudomonas aeruginosa: a two‐domain protein with a calcium binding parallel beta roll motif. , 1993, The EMBO journal.

[25]  J. Coote.  Structural and functional relationships among the RTX toxin determinants of gram-negative bacteria. , 1992, FEMS microbiology reviews.

[26]  R. Welch.  Pore‐forming cytolysins of Gram‐negative bacteria , 1991, Molecular microbiology.

[27]  W. Goebel,et al.  Pore formation by the Escherichia coli hemolysin: evidence for an association-dissociation equilibrium of the pore-forming aggregates , 1989, Infection and immunity.

[28]  N. Mackman,et al.  A novel C-terminal signal sequence targets Escherichia coli haemolysin directly to the medium , 1989, Journal of Cell Science.

[29]  A. Danchin,et al.  Secretion of cyclolysin, the calmodulin‐sensitive adenylate cyclase‐haemolysin bifunctional protein of Bordetella pertussis. , 1988, The EMBO journal.

[30]  R. Welch,et al.  RTX toxin structure and function: a story of numerous anomalies and few analogies in toxin biology. , 2001, Current topics in microbiology and immunology.