BET 1: Tranexamic acid in epistaxis: who bloody nose?
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A shortcut review was carried out to establish whether tranexamic acid is effective in controlling epistaxis. Three studies were directly relevant to the question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these studies are tabulated. The clinical bottom line is that there is not enough evidence to recommend tranexamic acid in the standard management of epistaxis.
[1] A. Ghasemi,et al. A new and rapid method for epistaxis treatment using injectable form of tranexamic acid topically: a randomized controlled trial. , 2013, The American journal of emergency medicine.
[2] M. Bende,et al. Effect of local tranexamic acid gel in the treatment of epistaxis. , 1995, ORL; journal for oto-rhino-laryngology and its related specialties.
[3] B. O'Reilly,et al. Oral tranexamic acid in the management of epistaxis. , 1988, Clinical otolaryngology and allied sciences.