A method for computer simulation of ultrasound Doppler color flow images--I. Theory and numerical method.

Ultrasound imaging systems utilizing the pulsed Doppler principle are capable of providing images of blood flow in real time. We present a useful method for simulating flow images on a computer. Our method assumes that blood and surrounding tissue consist of many point-like scatters positioned randomly in three dimensions. The position-dependent acoustic response of each scatterer is calculated using the acoustic impulse response method. This method takes into account the spatial effects of the transducer geometry on both the amplitude and temporal response of point-scattering. Details of theory, assumptions made in the simulation, and numerical methods are described fully for a spherically focused transducer, as well as a discussion of signal processing for generation of the flow image. Motion of a single scatterer is investigated to test the performance of the simulation algorithm. This simulation method could potentially be beneficial for detailed study of current and future flow imaging systems.

[1]  J. Roelandt,et al.  Color Doppler flow imaging and other advances in Doppler echocardiography , 1986 .

[2]  J. Woodcock,et al.  Doppler ultrasound and its use in clinical measurement , 1983 .

[3]  M S Patterson,et al.  Computer Simulations of Speckle in B-Scan Images , 1983, Ultrasonic imaging.

[4]  Vernon L. Newhouse,et al.  Analysis of Transit Time Effects on Doppler Flow Measurement , 1976, IEEE Transactions on Biomedical Engineering.

[5]  F. Foster,et al.  Ultrasound Transducers for Pulse-Echo Medical Imaging , 1983, IEEE Transactions on Biomedical Engineering.

[6]  P. Stepanishen Transient Radiation from Pistons in an Infinite Planar Baffle , 1970 .

[7]  C. Kasai,et al.  Real-Time Two-Dimensional Blood Flow Imaging Using an Autocorrelation Technique , 1985, IEEE Transactions on Sonics and Ultrasonics.

[8]  J C Bamber,et al.  Ultrasonic B-scanning: a computer simulation , 1980, Physics in medicine and biology.

[9]  C. Kasai,et al.  Real-Time Two-Dimensional Blood Flow Imaging Using Ultrasound Doppler , 1987 .

[10]  C. Merritt,et al.  Doppler color flow imaging , 1987, Journal of clinical ultrasound : JCU.

[11]  A. Kurjak,et al.  Conventional and color Doppler in the assessment of fetal and maternal circulation. , 1988, Ultrasound in medicine & biology.

[12]  R. Cobbold,et al.  "Speckle" in Continuous Wave Doppler Ultrasound Spectra: A Simulation Study , 1986, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[13]  B. Angelsen Instantaneous Frequency, Mean Frequency, and Variance of Mean Frequency Estimators for Ultrasonic Blood Velocity Doppler Signals , 1981, IEEE Transactions on Biomedical Engineering.

[14]  C. Kimme-Smith,et al.  Processing algorithms for color flow Doppler , 1989, Proceedings., IEEE Ultrasonics Symposium,.

[15]  M. Brandestini Topoflow - A digital full range Doppler velocity meter , 1978 .

[16]  Larry E. Miller,et al.  Real-time two-dimensional color-flow Doppler: Enhanced Doppler flow imaging in the diagnosis of cardiovascular disease , 1982 .

[17]  Mani Azimi,et al.  An Analytical Study of Doppler Ultrasound Systems1 , 1985 .

[18]  Richard S.C. Cobbold,et al.  Interpretation of power changes in Doppler signals from human blood-in vitro studies , 1988, IEEE 1988 Ultrasonics Symposium Proceedings..

[19]  E. O. Brigham,et al.  The Fast Fourier Transform , 1967, IEEE Transactions on Systems, Man, and Cybernetics.

[20]  D. Adler,et al.  Doppler ultrasound color flow imaging in the study of breast cancer: preliminary findings. , 1990, Ultrasound in medicine & biology.

[21]  D R Pedersen,et al.  A three-dimensional computational simulation of some sources of measurement artifact in microvascular pulsed ultrasound Doppler velocimetry. , 1985, Journal of biomechanical engineering.

[22]  Richard S. C. Cobbold,et al.  A Stochastic Model of the Backscattered Doppler Ultrasound from Blood , 1986, IEEE Transactions on Biomedical Engineering.

[23]  M Arditi,et al.  Transient fields of concave annular arrays. , 1981, Ultrasonic imaging.

[24]  J B Davey,et al.  Color Doppler signals from breast tumors. Work in progress. , 1990, Radiology.

[25]  Chihiro Kasai,et al.  Physics and Instrumentation of Doppler Color Flow Mapping , 1987 .

[26]  John M. Reid,et al.  Scattering of Ultrasound by Blood , 1976, IEEE Transactions on Biomedical Engineering.

[27]  O. Bonnefous,et al.  Time Domain Formulation of Pulse-Doppler Ultrasound and Blood Velocity Estimation by Cross Correlation , 1986, Ultrasonic imaging.