Sinonasal Lobular Capillary Hemangioma After Continuous Self-tests for COVID-19: A Case Report and Review of the Literature

Sinonasal lobular capillary hemangiomas (LCH) are rare benign vascular lesions commonly arising from the nasal septum. Nasopharyngeal, nasal mid-turbinate, and anterior nasal swabbing is the preferred method of screening for coronavirus disease-2019 (COVID-19). Herein, we present a case of a sinonasal LCH in a child after continuous self-tests for COVID-19, with an anterior nasal swab. The child presented with a well-defined red mass in the anterior part of the nasal septum, which was removed endoscopically. Histopathology revealed a LCH. This is the first report of a complication other than epistaxis with the use of an anterior nasal swab. Our literature review identified 32 studies reporting complications of COVID-19 screening. Cerebrospinal fluid leaks and foreign body retention are the most common ones. A proper specimen collection technique and a quick patient history with an emphasis on risk factors are the best practices to prevent complications from COVID-19 screening.

[1]  Yvonne Versluijs,et al.  Intestine perforation by an accidental ingested SARS-CoV-2 nasopharyngeal swab; a case report , 2022, International Journal of Surgery Case Reports.

[2]  L. Pignataro,et al.  Misdirection of a nasopharyngeal SARS-CoV-2 swab: An unexpected complication , 2022, Otolaryngology Case Reports.

[3]  A. Süslü,et al.  Covid-19 Nasopharyngeal Swab Related CSF Rhinorrhoea: A case report , 2022, Indian Journal of Otolaryngology and Head & Neck Surgery.

[4]  T. D. Bloom,et al.  Neurally Mediated Syncope Triggered by COVID-19 Nasopharyngeal Swab Specimen Collection: A Case Report , 2022, Allergy & rhinology.

[5]  R. Gomes,et al.  Ethmoidal silent sinus syndrome after nasal swab test , 2021, Neuroradiology.

[6]  D. Farina,et al.  How deep is too deep? Gastrointestinal complication of COVID-19 deep nasal swab testing , 2021, Endoscopy international open.

[7]  M. Samadian,et al.  CSF rhinorrhea after nasopharyngeal swab testing for COVID-19: A case report and review of literature , 2021, Otolaryngology Case Reports.

[8]  Y. Ducic,et al.  Cerebrospinal Fluid Leak From COVID-19 Swab , 2021, OTO open.

[9]  Riyadh Alhedaithy,et al.  Cerebrospinal fluid leak post COVID-19 nasopharyngeal swab for a patient with idiopathic intracranial hypertension: a case report , 2021, Journal of surgical case reports.

[10]  J. Vodička,et al.  Cribriform Plate Injury After Nasal Swab Testing for COVID-19. , 2021, JAMA otolaryngology-- head & neck surgery.

[11]  S. Ulualp,et al.  Recurrent Epistaxis and Unilateral Intranasal Mass in A Teenager , 2021, The American journal of case reports.

[12]  R. Naclerio,et al.  Complications of nasal SARS-CoV-2 testing: a review , 2021, Journal of Investigative Medicine.

[13]  A. Holmes,et al.  Case Report: An Intracranial Complication of COVID-19 Nasopharyngeal Swab , 2021, Clinical practice and cases in emergency medicine.

[14]  C. Parrilla,et al.  A Nasal Complication of Nasopharyngeal Swab for Reverse Transcription Polymerase Chain Reaction (RT-PCR) Detection of SARS-CoV-2 mRNA , 2021, Cureus.

[15]  M. Yılmaz,et al.  A brief report: Cerebrospinal fluid rhinorrhea after repetitive nasal swab testing for coronavirus disease 2019(COVID-19) , 2021, Otolaryngology Case Reports.

[16]  A. Cervin,et al.  COVID‐19 swab‐related skull base injury , 2021, The Medical journal of Australia.

[17]  F. Zsigmond,et al.  Safety Precautions for Self-Performed Severe Acute Respiratory Syndrome Coronavirus 2 Tests: A Case of a Swallowed Swab , 2021, Cureus.

[18]  B. Fazekas,et al.  Preseptal cellulitis and infraorbital abscess as a complication of a routine COVID-19 swab , 2021, BMJ Case Reports.

[19]  M. Tolvi,et al.  Complications of COVID-19 Nasopharyngeal Swab Test. , 2021, JAMA otolaryngology-- head & neck surgery.

[20]  A. Psaltis,et al.  COVID‐19 nasopharyngeal swab causing a traumatic cerebrospinal fluid leak , 2021, ANZ journal of surgery.

[21]  M. Tümer,et al.  A fractured nasopharyngeal swab in the duodenum of a toddler: an unusual complication of preoperative COVID-19 testing , 2021, Canadian Journal of Anesthesia/Journal canadien d'anesthésie.

[22]  G. Zuccotti,et al.  An Unusual Retained Choanal Foreign Body: A Possible Complication of COVID-19 Testing With Nasopharyngeal Swab , 2021, Ear, nose, & throat journal.

[23]  F. Vale,et al.  CSF Leak After COVID‐19 Nasopharyngeal Swab: A Case Report , 2021, The Laryngoscope.

[24]  C. Dupuis,et al.  Pharyngeal abscess: a rare complication of repeated nasopharyngeal swabs , 2021, Intensive Care Medicine.

[25]  M. Álvarez-Sauco,et al.  Meningitis due to cerebrospinal fluid leak after nasal swab testing for COVID‐19 , 2021, European journal of neurology.

[26]  J. Rajah,et al.  CSF rhinorrhoea post COVID-19 swab: A case report and review of literature , 2021, Journal of Clinical Neuroscience.

[27]  Varun Suresh Anesthesia for extraction of a fractured COVID-19 nasopharyngeal swab , 2021, International Journal of Pediatric Otorhinolaryngology.

[28]  J. Rupp,et al.  Complications of nasal and pharyngeal swabs: a relevant challenge of the COVID-19 pandemic? , 2020, European Respiratory Journal.

[29]  M. Wyman,et al.  Nasal Foreign Body, an Unanticipated Complication of COVID-19 Care: A Case Report , 2020, The Journal of Emergency Medicine.

[30]  P. Boscolo-Rizzo,et al.  Is oro/nasopharyngeal swab for SARS-CoV-2 detection a safe procedure? Complications observed among a case series of 4876 consecutive swabs , 2020, American Journal of Otolaryngology.

[31]  J. Greenlee,et al.  Cerebrospinal Fluid Leak After Nasal Swab Testing for Coronavirus Disease 2019. , 2020, JAMA otolaryngology-- head & neck surgery.

[32]  L. De Luca,et al.  Is naso-pharyngeal swab always safe for SARS-CoV-2 testing? An unusual, accidental foreign body swallowing , 2020, Clinical Journal of Gastroenterology.

[33]  A. Azar,et al.  Fractured aluminum nasopharyngeal swab during drive-through testing for COVID-19: radiographic detection of a retained foreign body , 2020, Skeletal Radiology.

[34]  T. Valsamakis,et al.  Tracheal swab from front of neck airway for SARS-CoV-2; a bronchial foreign body , 2020, BMJ Case Reports.

[35]  E. Luff,et al.  Test, test, test – a complication of testing for coronavirus disease 2019 with nasal swabs , 2020, The Journal of Laryngology & Otology.

[36]  G. Macedo,et al.  An unusual collateral damage of COVID-19 pandemic , 2020, Gastrointestinal Endoscopy.

[37]  F. Simon,et al.  How to perform a nasopharyngeal swab in adults and children in the COVID-19 era , 2020, European Annals of Otorhinolaryngology, Head and Neck Diseases.

[38]  Hiroyuki Takahashi,et al.  Features of sinonasal hemangioma: A retrospective study of 31 cases. , 2017, Auris, nasus, larynx.

[39]  Jong Seung Kim,et al.  Sinonasal Hemangioma: Diagnosis, Treatment, and Follow-Up of 37 Patients at a Single Center. , 2017, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[40]  A. Kacker,et al.  Demographics and etiologic factors of nasal pyogenic granuloma , 2016, International forum of allergy & rhinology.

[41]  F. Mariño‐Sánchez,et al.  Pediatric intranasal lobular capillary hemangioma: Report of two new cases and review of the literature , 2016, Respiratory medicine case reports.