Stent Deployment in Old Saphenous Vein Grafts with the Use of a Protection Device

We present two cases of patients with coronary artery disease who had undergone coronary artery bypass surgery and had developed significant disease in the saphenous vein grafts. Coronary angiography revealed complicated lesions in both cases as a result of the age of the grafts, which created a high risk for distal embolization during the interventional procedure. We decided to treat these lesions using un umbrella-type filter protection device (Angioguard) during the angioplasty procedure, in order to capture embolic material and thrombi from the degenerative lesions of these old vein grafts and avoid peripheral obstruction in the microcirculation with all the subsequent consequences. In one of the cases the emboli that were captured were visually detected but in the other no macroscopic emboli were detected. However, both patients were successfully treated without any evidence of distal embolization. The importance of coronary microvasculature protection and the use of such devices that can make coronary interventions safer is discussed in brief.

[1]  W. O’Neill,et al.  Long-term clinical outcome and predictors of major adverse cardiac events after percutaneous interventions on saphenous vein grafts. , 2001, Journal of the American College of Cardiology.

[2]  S. Sdringola,et al.  Percutaneous intervention in saphenous venous grafts: in-stent restenosis lesions are safer than de novo lesions. , 2001, The Journal of invasive cardiology.

[3]  M. Kern,et al.  The coronary no-reflow phenomenon: a review of mechanisms and therapies. , 2001, European heart journal.

[4]  C. Vlachopoulos,et al.  Stents covered by autologous venous grafts: feasibility and immediate and long-term results. , 2000, American heart journal.

[5]  E. Topol,et al.  Recognition of the importance of embolization in atherosclerotic vascular disease. , 2000, Circulation.

[6]  O. Rosales,et al.  Intracoronary adenosine administered during rotational atherectomy of complex lesions in native coronary arteries reduces the incidence of no‐reflow phenomenon , 1999 .

[7]  Katherine C. Wu,et al.  Prognostic significance of microvascular obstruction by magnetic resonance imaging in patients with acute myocardial infarction. , 1998, Circulation.

[8]  O. Rosales,et al.  Intracoronary adenosine administered during rotational atherectomy of complex lesions in native coronary arteries reduces the incidence of no-reflow phenomenon. , 1998, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[9]  J. M. Bloom Stent placement compared with balloon angioplasty for obstructed coronary bypass grafts. , 1998, The New England journal of medicine.

[10]  J. Dougherty,et al.  Treatment of thrombotic saphenous vein bypass grafts using local urokinase infusion therapy with the Dispatch catheter. , 1997, Catheterization and cardiovascular diagnosis.

[11]  E. Jones,et al.  Outcome of reoperative coronary bypass surgery versus coronary angioplasty after previous bypass surgery. , 1997, Circulation.

[12]  E. Topol,et al.  The myth of the myocardial 'infarctlet' during percutaneous coronary revascularization procedures. , 1996, Circulation.

[13]  D. Baim,et al.  Editorial comment: Understanding the “no‐reflow” problem , 1996 .

[14]  W J Keon,et al.  Coronary bypass graft fate and patient outcome: angiographic follow-up of 5,065 grafts related to survival and reoperation in 1,388 patients during 25 years. , 1996, Journal of the American College of Cardiology.

[15]  J. Tcheng Glycoprotein IIb/IIIa receptor inhibitors: putting the EPIC, IMPACT II, RESTORE, and EPILOG trials into perspective. , 1996, The American journal of cardiology.

[16]  M. Hori,et al.  Clinical implications of the 'no reflow' phenomenon. A predictor of complications and left ventricular remodeling in reperfused anterior wall myocardial infarction. , 1996, Circulation.

[17]  W. O’Neill,et al.  Recanalization of Chronically Occluded Aortocoronary Saphenous Vein Bypass Grafts With Long-Term, Low Dose Direct Infusion of Urokinase (ROBUST): a serial trial. , 1996, Journal of the American College of Cardiology.

[18]  D. Baim,et al.  Understanding the "no-reflow" problem. , 1996, Catheterization and cardiovascular diagnosis.

[19]  B. Chaitman,et al.  Comparison of 15-year survival for men and women after initial medical or surgical treatment for coronary artery disease: a CASS registry study. Coronary Artery Surgery Study. , 1995, Journal of the American College of Cardiology.

[20]  D. Baim,et al.  Incidence and treatment of 'no-reflow' after percutaneous coronary intervention. , 1994, Circulation.

[21]  E. Jones,et al.  Frequency of repeat coronary bypass or coronary angioplasty after coronary artery bypass surgery using saphenous venous grafts. , 1994, The American journal of cardiology.

[22]  W. Keon,et al.  Coronary bypass graft fate: long-term angiographic study. , 1991, Journal of the American College of Cardiology.