Immunomodulator plasmid projected by systems biology as a candidate for the development of adjunctive therapy for respiratory syncytial virus infection.
暂无分享,去创建一个
R. Stein | J. Vargas | A. P. D. de Souza | B. Porto | T. Fazolo | F. Q. Mayer | P. Pitrez
[1] A. M. Collier,et al. Respiratory-syncytial-virus infections, reinfections and immunity. A prospective, longitudinal study in young children. , 1979, The New England journal of medicine.
[2] W. P. Glezen,et al. Risk of primary infection and reinfection with respiratory syncytial virus. , 1986, American journal of diseases of children.
[3] F. W. Denny,et al. Acute respiratory infections are the leading cause of death in children in developing countries. , 1986, The American journal of tropical medicine and hygiene.
[4] R. Fernandez-Botran,et al. Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells , 1988, Nature.
[5] Li Zhu,et al. Multicomponent gene therapy vaccines for lung cancer: effective eradication of established murine tumors in vivo with interleukin-7/herpes simplex thymidine kinase-transduced autologous tumor and ex vivo activated dendritic cells , 1997, Gene Therapy.
[6] E. Gelfand,et al. Respiratory syncytial virus infection results in airway hyperresponsiveness and enhanced airway sensitization to allergen. , 1997, The Journal of clinical investigation.
[7] W. Calhoun,et al. Respiratory syncytial virus infection in infants is associated with predominant Th-2-like response. , 1997, American journal of respiratory and critical care medicine.
[8] W. Fiers,et al. Macrophages induce cellular immunity by activating Th1 cell responses and suppressing Th2 cell responses. , 1998, Journal of immunology.
[9] D. Collen,et al. Aerosol Gene Transfer With Inducible Nitric Oxide Synthase Reduces Hypoxic Pulmonary Hypertension and Pulmonary Vascular Remodeling in Rats , 2000, Circulation.
[10] N. Glaichenhaus,et al. The role of antigen and IL-12 in sustaining Th1 memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[11] Stéphan Vagner,et al. Irresistible IRES , 2001, EMBO reports.
[12] R. Lempicki,et al. Increased peripheral expansion of naive CD4+ T cells in vivo after IL-2 treatment of patients with HIV infection , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[13] Philip Smith,et al. IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13. , 2002, Immunity.
[14] C. Dye,et al. Estimates of world-wide distribution of child deaths from acute respiratory infections. , 2002, The Lancet. Infectious diseases.
[15] B. Graham,et al. NK T Cells Contribute to Expansion of CD8+ T Cells and Amplification of Antiviral Immune Responses to Respiratory Syncytial Virus , 2002, Journal of Virology.
[16] J. Bijlsma,et al. Differentiation of naive CD4+ T cells towards T helper 2 cells is not impaired in rheumatoid arthritis patients , 2003, Arthritis research & therapy.
[17] M. Małecki,et al. Construction of a bicistronic proangiogenic expression vector and its application in experimental angiogenesis in vivo. , 2003, Acta biochimica Polonica.
[18] S. Johnston,et al. Type 1 and type 2 cytokine imbalance in acute respiratory syncytial virus bronchiolitis. , 2003, American journal of respiratory and critical care medicine.
[19] Mark E. J. Newman. A measure of betweenness centrality based on random walks , 2005, Soc. Networks.
[20] D. Mann,et al. Peptide-based candidate vaccine against respiratory syncytial virus. , 2005, Vaccine.
[21] R. Karron,et al. Identification of a recombinant live attenuated respiratory syncytial virus vaccine candidate that is highly attenuated in infants. , 2005, The Journal of infectious diseases.
[22] M. Bushell,et al. Internal ribosome entry segment-mediated translation during apoptosis: the role of IRES-trans-acting factors , 2005, Cell Death and Differentiation.
[23] K. Jooss,et al. Stable antibody expression at therapeutic levels using the 2A peptide , 2005, Nature Biotechnology.
[24] M. Kolb,et al. Gene therapy for pulmonary diseases. , 2006, Chest.
[25] S. L. Hyatt,et al. Plasmid size up to 20 kbp does not limit effective in vivo lung gene transfer using compacted DNA nanoparticles , 2006, Gene Therapy.
[26] Y. Becker. Respiratory syncytial virus (RSV) evades the human adaptive immune system by skewing the Th1/Th2 cytokine balance toward increased levels of Th2 cytokines and IgE, markers of allergy—a review , 2006, Virus Genes.
[27] B. Graham,et al. Viral and Host Factors in Human Respiratory Syncytial Virus Pathogenesis , 2007, Journal of Virology.
[28] C. Cho,et al. Aerosol delivery of Akt controls protein translation in the lungs of dual luciferase reporter mice , 2007, Gene Therapy.
[29] Stephen B. Johnson,et al. Research Paper: Topological Analysis of Large-scale Biomedical Terminology Structures , 2007, J. Am. Medical Informatics Assoc..
[30] E. Walsh,et al. Human infant respiratory syncytial virus (RSV)-specific type 1 and 2 cytokine responses ex vivo during primary RSV infection. , 2007, The Journal of infectious diseases.
[31] E. Piippo-Savolainen,et al. Wheezy babies—wheezy adults? Review on long‐term outcome until adulthood after early childhood wheezing , 2007, Acta paediatrica.
[32] Minlie Huang,et al. Mining physical protein-protein interactions from the literature , 2008, Genome Biology.
[33] Quan Pan,et al. PPLook: an automated data mining tool for protein-protein interaction , 2010, BMC Bioinformatics.
[34] K. Poehling,et al. The burden of respiratory syncytial virus infection in young children. , 2009, The New England journal of medicine.
[35] G. Bormans,et al. Highly efficient multicistronic lentiviral vectors with peptide 2A sequences. , 2009, Human gene therapy.
[36] F. Schellevis,et al. Progress in the surveillance of respiratory syncytial virus (RSV) in Europe: 2001-2008. , 2009, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.
[37] R. Flavell,et al. How are T(H)1 and T(H)2 effector cells made? , 2009, Current opinion in immunology.
[38] M. He,et al. PPI Finder: A Mining Tool for Human Protein-Protein Interactions , 2009, PloS one.
[39] W. Paul,et al. Differentiation of effector CD4 T cell populations (*). , 2010, Annual review of immunology.
[40] Gary D. Bader,et al. The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function , 2010, Nucleic Acids Res..
[41] Dariusz Plewczynski,et al. Protein-protein interaction and pathway databases, a graphical review , 2011, Briefings Bioinform..
[42] G. Laurent,et al. Nebulisation of Receptor-Targeted Nanocomplexes for Gene Delivery to the Airway Epithelium , 2011, PloS one.
[43] Miguel A. Andrade-Navarro,et al. PESCADOR, a web-based tool to assist text-mining of biointeractions extracted from PubMed queries , 2011, BMC Bioinformatics.
[44] H. Park,et al. High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice , 2011, PloS one.
[45] J. O’Shea,et al. Helper T cell diversity and plasticity. , 2012, Current opinion in immunology.
[46] Joshua W. Vincentz,et al. Twist1 Regulates Ifng Expression in Th1 Cells by Interfering with Runx3 Function , 2012, The Journal of Immunology.
[47] Andrew J. Oler,et al. The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses. , 2012, Immunity.
[48] S. van Drunen Littel-van den Hurk,et al. Pathogenesis of respiratory syncytial virus. , 2012, Current opinion in virology.
[49] Cathy H. Wu,et al. The eFIP system for text mining of protein interaction networks of phosphorylated proteins , 2012, Database J. Biol. Databases Curation.
[50] William A Prescott,et al. Cost Effectiveness of Respiratory Syncytial Virus Prophylaxis , 2012, PharmacoEconomics.
[51] E. Walsh,et al. Subunit and virus-like particle vaccine approaches for respiratory syncytial virus. , 2013, Current topics in microbiology and immunology.
[52] D. Lewis,et al. Human Neonatal Naive CD4+ T Cells Have Enhanced Activation-Dependent Signaling Regulated by the MicroRNA miR-181a , 2013, The Journal of Immunology.
[53] R. Karron,et al. Live-attenuated respiratory syncytial virus vaccines. , 2013, Current topics in microbiology and immunology.
[54] T. So,et al. Homeostatic Proliferation of Naive CD4+ T Cells in Mesenteric Lymph Nodes Generates Gut-Tropic Th17 Cells , 2013, The Journal of Immunology.
[55] S. Jarriault,et al. Simultaneous Expression of Multiple Proteins Under a Single Promoter in Caenorhabditis elegans via a Versatile 2A-Based Toolkit , 2013, Genetics.
[56] K. O'Neil,et al. Inhalation delivery of protein therapeutics. , 2013, Inflammation & allergy drug targets.
[57] James J. Yoo,et al. MYOD mediates skeletal myogenic differentiation of human amniotic fluid stem cells and regeneration of muscle injury , 2013, Stem Cell Research & Therapy.
[58] D. Hayes,et al. Respiratory syncytial virus: current and emerging treatment options , 2014, ClinicoEconomics and outcomes research : CEOR.
[59] H. Koskela,et al. Adults face increased asthma risk after infant RSV bronchiolitis and reduced respiratory health‐related quality of life after RSV pneumonia , 2014, Acta paediatrica.
[60] T. Lazzarotto,et al. Respiratory Syncytial Virus Infections in Infants Affected by Primary Immunodeficiency , 2014, Journal of immunology research.
[61] K. Sala,et al. Factors associated with disease severity in children with bronchiolitis , 2015, The Journal of asthma : official journal of the Association for the Care of Asthma.