Neurohistochemical biomarkers of the marine neurotoxicant, domoic acid.

[1]  L. Schmued,et al.  Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons , 2005, Brain Research.

[2]  B. Thorn,et al.  Electroencephalographic, behavioral, and c-fos responses to acute domoic acid exposure. , 2004, Neurotoxicology and teratology.

[3]  Y. Otsuki,et al.  Identification of c-Jun as bcl-2 Transcription Factor in Human Uterine Endometrium , 2003, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[4]  M. Silver,et al.  From sanddabs to blue whales: the pervasiveness of domoic acid. , 2002, Toxicon : official journal of the International Society on Toxinology.

[5]  P. Gopalakrishnakone,et al.  Domoic acid‐induced neuronal damage in the rat hippocampus: Changes in apoptosis related genes (Bcl‐2, Bax, caspase‐3) and microglial response , 2001, Journal of neuroscience research.

[6]  L. Schmued,et al.  Fluoro-Jade and silver methods: application to the neuropathology of scrapie, a transmissible spongiform encephalopathy. , 2001, Brain research. Brain research protocols.

[7]  R. Griffiths,et al.  Possible role for the FosB/JunD AP‐1 transcription factor complex in glutamate‐mediated excitotoxicity in cultured cerebellar granule cells , 2000, Journal of neuroscience research.

[8]  W. Slikker,et al.  A dose-response study of ibogaine-induced neuropathology in the rat cerebellum. , 2000, Toxicological sciences : an official journal of the Society of Toxicology.

[9]  A. Scallet,et al.  Quantitating silver-stained neurodegeneration: the neurotoxicity of trimethlytin (TMT) in aged rats , 2000, Journal of Neuroscience Methods.

[10]  L. Schmued,et al.  Temporal progression of kainic acid induced neuronal and myelin degeneration in the rat forebrain , 2000, Brain Research.

[11]  A. Hamberger,et al.  Quantitative immunochemistry on neuronal loss, reactive gliosis and BBB damage in cortex/striatum and hippocampus/amygdala after systemic kainic acid administration , 2000, Neurochemistry International.

[12]  Roman Marin,et al.  Mortality of sea lions along the central California coast linked to a toxic diatom bloom , 2000, Nature.

[13]  L. Schmued,et al.  Fluoro-Jade: Novel Fluorochromes for Detecting Toxicant-Induced Neuronal Degeneration , 2000, Toxicologic pathology.

[14]  W. Slikker,et al.  Black-Gold: a simple, high-resolution histochemical label for normal and pathological myelin in brain tissue sections , 1999, Brain Research.

[15]  R. Tjeerdema,et al.  Detection of domoic acid in northern anchovies and California sea lions associated with an unusual mortality event. , 1999, Natural toxins.

[16]  S. Sato,et al.  Confirmation of domoic acid production of Pseudo-nitzschia multiseries isolated from Ofunato Bay, Japan. , 1999, Toxicon : official journal of the International Society on Toxinology.

[17]  M. Takigawa,et al.  Kainic and domoic acids differentially affect NADPH-diaphorase neurons in the mouse hippocampal formation , 1999, Brain Research Bulletin.

[18]  D. J. Douglas,et al.  Biosynthesis of domoic acid by the diatom Pseudo-nitzschia multiseries. , 1998, Natural toxins.

[19]  D. Hampson,et al.  The activation of glutamate receptors by kainic acid and domoic acid. , 1998, Natural toxins.

[20]  A. Planas,et al.  Radiation-induced apoptosis in developing rats and kainic acid-induced excitotoxicity in adult rats are associated with distinctive morphological and biochemical c-Jun/AP-1 (N) expression , 1997, Neuroscience.

[21]  S. Rapoport,et al.  Sequelae of parenteral domoic acid administration in rats: Comparison of effects on different anatomical markers in brain , 1997, Synapse.

[22]  William Slikker,et al.  Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration , 1997, Brain Research.

[23]  T. Noguchi,et al.  Two new isomers of domoic acid from a red alga, Chondria armata. , 1997, Toxicon : official journal of the International Society on Toxinology.

[24]  A. Scallet,et al.  Domoic acid: neurobehavioral and neurohistological effects of low-dose exposure in adult rats. , 1996, Neurotoxicology and teratology.

[25]  A. Scallet,et al.  Ibogaine Produces Neurodegeneration in Rat, but Not Mouse, Cerebellum , 1996, Annals of the New York Academy of Sciences.

[26]  J. Ramsdell,et al.  Brain Fos induction is a sensitive biomarker for the lowest observed neuroexcitatory effects of domoic acid. , 1996, Fundamental and applied toxicology : official journal of the Society of Toxicology.

[27]  W. Slikker,et al.  The effects of perinatal hypoxia on the behavioral, neurochemical, and neurohistological toxicity of the metabolic inhibitor 3-nitropropionic acid , 1995, Metabolic Brain Disease.

[28]  W. Slikker,et al.  Domoic acid-induced neuronal degeneration in the primate forebrain revealed by degeneration specific histochemistry , 1995, Brain Research.

[29]  G. Iwama,et al.  Haemocyte changes in the Pacific oyster, Crassostrea gigas, caused by exposure to domoic acid in the diatom Pseudonitzschia pungens f. multiseries. , 1995, Toxicon : official journal of the International Society on Toxinology.

[30]  R. Zatorre,et al.  Temporal lobe epilepsy caused by domoic acid intoxication: Evidence for glutamate receptor–mediated excitotoxicity in humans , 1995, Annals of neurology.

[31]  A. Scallet,et al.  The effects of reduced perfusion and reperfusion on C-fos and HSP-72 protein immunohistochemistry in gestational day 21 rat brains , 1994, International Journal of Developmental Neuroscience.

[32]  D. J. Douglas,et al.  Genetic relatedness of toxic and nontoxic isolates of the marine pennate diatom Pseudonitzschia (Bacillariophyceae): phylogenetic analysis of 18S rRNA sequences. , 1994, Natural toxins.

[33]  F. Chavez,et al.  Ribosomal DNA sequences discriminate among toxic and non-toxic Pseudonitzschia species. , 1994, Natural toxins.

[34]  T. B. Taylor,et al.  Neuroexcitatory and neurotoxic actions of the amnesic shellfish poison, domoic acid. , 1994, Neuroreport.

[35]  J. McCabe,et al.  Double immunofluorescence staining of Fos and Jun in the hypothalamus of the rat , 1994, Cell and Tissue Research.

[36]  F. Iverson,et al.  Serum domoic acid clearance and clinical observations in the cynomolgus monkey and Sprague-Dawley rat following a single IV dose , 1994, Bulletin of environmental contamination and toxicology.

[37]  W. Slikker,et al.  Domoic acid-treated cynomolgus monkeys (M. fascicularis): effects of dose on hippocampal neuronal and terminal degeneration , 1993, Brain Research.

[38]  S. Hierlihy,et al.  Renal clearance of domoic acid in the rat. , 1993, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[39]  P. Krogsgaard‐Larsen,et al.  Naturally-occurring excitatory amino acids as neurotoxins and leads in drug design. , 1992, Toxicology letters.

[40]  S. M. Strain,et al.  Morphine differentially affects domoic acid and kainic acid toxicity in vivo. , 1992, Neuroreport.

[41]  T. Ishida,et al.  Conformational feature of neuroactive domoic acid: X-ray structural comparison with isodomoic acid A and alpha-kainic acid. , 1992, Biochemical and biophysical research communications.

[42]  G. Fryxell,et al.  Detection of the marine toxins okadaic acid and domoic acid in shellfish and phytoplankton in the Gulf of Mexico. , 1992, Toxicon : official journal of the International Society on Toxinology.

[43]  R. Tasker,et al.  Hippocampal damage produced by systemic injections of domoic acid in mice , 1991, Neuroscience.

[44]  E. Preston,et al.  Transfer Constants for Blood-Brain Barrier Permeation of the Neuroexcitatory Shellfish Toxin, Domoic Acid , 1991, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[45]  R. Sutherland,et al.  Domoic acid, an environmental toxin, produces hippocampal damage and severe memory impairment , 1990, Neuroscience Letters.

[46]  J. Olney,et al.  Domoic acid: A dementia-inducing excitotoxic food poison with kainic acid receptor specificity , 1990, Experimental Neurology.

[47]  E. Nera,et al.  The toxicology of domoic acid administered systemically to rodents and primates. , 1990, Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada.

[48]  T. Kosatsky,et al.  Amnesic shellfish poisoning: a new clinical syndrome due to domoic acid. , 1990, Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada.

[49]  G. Debonnel,et al.  Neurotoxic effect of domoic acid: mediation by kainate receptor electrophysiological studies in the rat. , 1990, Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada.

[50]  Alan C. Evans,et al.  PET studies of domoic acid poisoning in humans: excitotoxic destruction of brain glutamatergic pathways, revealed in measurements of glucose metabolism by positron emission tomography. , 1990, Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada.

[51]  Zatorre Rj.  Memory loss following domoic acid intoxication from ingestion of toxic mussels. , 1990 .

[52]  J. Teitelbaum.  Acute manifestations of domoic acid poisoning: case presentations. , 1990, Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada.

[53]  T. Perl,et al.  Domoic acid toxicity. Panel discussion: definition of the syndrome. , 1990, Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada.

[54]  R. Zatorre,et al.  Neurological sequelae of domoic acid intoxication. , 1990, Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada.

[55]  R. Zatorre,et al.  Neurologic sequelae of domoic acid intoxication due to the ingestion of contaminated mussels. , 1990, The New England journal of medicine.

[56]  T. Perl,et al.  An outbreak of toxic encephalopathy caused by eating mussels contaminated with domoic acid. , 1990, The New England journal of medicine.

[57]  F. Iverson,et al.  Acute Parenteral Neurotoxicity of Domoic Acid in Cynomolgus Monkeys (M. fascicularis) , 1990, Toxicologic pathology.

[58]  F. Iverson,et al.  Neuropathology of Excitatory Neurotoxins: The Domoic Acid Model , 1990, Toxicologic pathology.

[59]  G. Glavin,et al.  Kynurenic acid protects against gastroduodenal ulceration in mice injected with extracts from poisonous atlantic shellfish , 1989, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[60]  F. Joó,et al.  Effects of dexamethasone on brain edema induced by kainic acid seizures , 1986, Neuroscience.

[61]  R. S. Sloviter,et al.  On the relationship between kainic acid-induced epileptiform activity and hippocampal neuronal damage , 1981, Neuropharmacology.

[62]  Tsunematsu Takemoto,et al.  ハナヤナギの成分研究(第8報) : Domoic Acidの構造論 その1 , 1966 .

[63]  O. Pulido,et al.  30-day oral toxicity study of domoic acid in cynomolgus monkeys: lack of overt toxicity at doses approaching the acute toxic dose. , 1997, Natural toxins.

[64]  Louis W. Chang,et al.  Neurotoxicology : approaches and methods , 1995 .

[65]  A. Scallet.  Quantitative Morphometry for Neurotoxicity Assessment , 1995 .

[66]  G. Iwama,et al.  Effects of domoic acid on haemolymph pH, PCO2 and PO2 in the Pacific oyster, Crassostrea gigas and the California mussel, Mytilus californianus , 1995 .

[67]  W. Pardridge,et al.  The Blood-brain barrier : cellular and molecular biology , 1993 .

[68]  E. Nera,et al.  Experimental oral toxicity of domoic acid in cynomolgus monkeys (Macaca fascicularis) and rats. Preliminary investigations. , 1990, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[69]  E. Nera,et al.  Domoic acid poisoning and mussel-associated intoxication: preliminary investigations into the response of mice and rats to toxic mussel extract. , 1989, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[70]  W. Slikker,et al.  Neuropathological evaluation by combined immunohistochemistry and degeneration-specific methods: application to methylenedioxymethamphetamine. , 1988, Neurotoxicology.

[71]  R. C. Collins,et al.  Excitotoxic mechanisms of epileptic brain damage. , 1986, Advances in neurology.

[72]  G. Paxinos,et al.  The Rat Brain in Stereotaxic Coordinates , 1983 .

[73]  Olney Jw,et al.  Status epilepticus in the limbic system: biochemical and pathological changes. , 1983 .