Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

[1]  A. Ullrich,et al.  Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis. , 1993, Cancer research.

[2]  Bing Li,et al.  Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo , 1993, Nature.

[3]  A. Ullrich,et al.  High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis , 1993, Cell.

[4]  Georg Breier,et al.  Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo , 1992, Nature.

[5]  E. Keshet,et al.  Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis , 1992, Nature.

[6]  H Ueno,et al.  The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. , 1992, Science.

[7]  E. Wagner,et al.  Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutants , 1992, Molecular and cellular biology.

[8]  M. Kirschner,et al.  Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos , 1991, Cell.

[9]  H. Ueno,et al.  Inhibition of PDGF beta receptor signal transduction by coexpression of a truncated receptor , 1991, Science.

[10]  A. Ullrich,et al.  A dominant negative mutation suppresses the function of normal epidermal growth factor receptors by heterodimerization , 1991, Molecular and cellular biology.

[11]  J. Gorski,et al.  PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. , 1990, Science.

[12]  J. Folkman What is the evidence that tumors are angiogenesis dependent? , 1990, Journal of the National Cancer Institute.

[13]  W. Risau,et al.  Angiogenic growth factors. , 1990, Progress in growth factor research.

[14]  Miller Ad,et al.  Improved Retroviral Vectors for Gene Transfer and Expression , 1989 .

[15]  C. Gorman,et al.  The human cytomegalovirus major immediate early promoter can be trans-activated by adenovirus early proteins. , 1989, Virology.

[16]  D. Hanahan,et al.  Induction of angiogenesis during the transition from hyperplasia to neoplasia , 1989, Nature.

[17]  H. Okayama,et al.  High-efficiency transformation of mammalian cells by plasmid DNA. , 1987, Molecular and cellular biology.

[18]  E. Wagner,et al.  Expression of retroviral vectors in transgenic mice obtained by embryo infection. , 1987, The EMBO journal.