Signaling in Leukocyte Transendothelial Migration
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[1] A. Wittinghofer,et al. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP , 1998, Nature.
[2] E. Génot,et al. Inhibitory control of TGF‐β1 on the activation of Rap1, CD11b, and transendothelial migration of leukocytes , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[3] Z. Q. Yang,et al. Both N-terminal myosin-binding and C-terminal actin-binding sites on smooth muscle caldesmon are required for caldesmon-mediated inhibition of actin filament velocity. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[4] Donna J. Webb,et al. Adhesion assembly, disassembly and turnover in migrating cells – over and over and over again , 2002, Nature Cell Biology.
[5] E. Dejana,et al. Leukocyte Recruitment in the Cerebrospinal Fluid of Mice with Experimental Meningitis Is Inhibited by an Antibody to Junctional Adhesion Molecule (Jam) , 1999, The Journal of experimental medicine.
[6] R. Wolthuis,et al. The Small Gtpase, Rap1, Mediates Cd31-Induced Integrin Adhesion , 2000, The Journal of cell biology.
[7] W. Muller,et al. CD99 plays a major role in the migration of monocytes through endothelial junctions , 2002, Nature Immunology.
[8] M. Corada,et al. Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions , 1996, The Journal of cell biology.
[9] R. Alon,et al. The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice. , 2000, Blood.
[10] J W Sedat,et al. Dynamics of a chemoattractant receptor in living neutrophils during chemotaxis. , 1999, Molecular biology of the cell.
[11] B. Torbett,et al. Presentation of chemokine SDF-1 alpha by fibronectin mediates directed migration of T cells. , 2000, Blood.
[12] Benjamin Geiger,et al. How do microtubules guide migrating cells? , 2002, Nature Reviews Molecular Cell Biology.
[13] F. Maxfield,et al. Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis , 2003, Nature.
[14] T. Mak,et al. Platelet-endothelial cell adhesion molecule-1 (PECAM-1)-deficient mice demonstrate a transient and cytokine-specific role for PECAM-1 in leukocyte migration through the perivascular basement membrane. , 2001, Blood.
[15] John G. Collard,et al. Inhibition of invasion of epithelial cells by Tiam1-Rac signaling. , 1997, Science.
[16] M. Gold,et al. The Rap GTPases Regulate B Cell Migration Toward the Chemokine Stromal Cell-Derived Factor-1 (CXCL12): Potential Role for Rap2 in Promoting B Cell Migration1 , 2002, The Journal of Immunology.
[17] John G. Collard,et al. Rap1 Regulates E-cadherin-mediated Cell-Cell Adhesion* , 2004, Journal of Biological Chemistry.
[18] J. V. van Buul,et al. Trading spaces: Rap, Rac, and Rho as architects of transendothelial migration , 2005, Current opinion in hematology.
[19] K. Rogers,et al. Changes in the distribution of LFA-1, catenins, and F-actin during transendothelial migration of monocytes in culture. , 1997, Journal of cell science.
[20] V. Krymskaya,et al. VCAM-1 Activates Phosphatidylinositol 3-Kinase and Induces p120Cbl Phosphorylation in Human Airway Smooth Muscle Cells 1 , 2001, The Journal of Immunology.
[21] A. Verin,et al. Microtubule disassembly increases endothelial cell barrier dysfunction: role of MLC phosphorylation. , 2001, American journal of physiology. Lung cellular and molecular physiology.
[22] A. Zernecke,et al. JAM-1 is a ligand of the β2 integrin LFA-1 involved in transendothelial migration of leukocytes , 2002, Nature Immunology.
[23] T. Springer,et al. Contrasting responses to multiple chemotactic stimuli in transendothelial migration: heterologous desensitization in neutrophils and augmentation of migration in eosinophils. , 1997, Journal of immunology.
[24] T. Carlos,et al. Leukocyte-endothelial adhesion molecules. , 1994, Blood.
[25] H. Bourne,et al. Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products. , 2000, Trends in cell biology.
[26] S. Døskeland,et al. cAMP effector mechanisms. Novel twists for an ‘old’ signaling system , 2003, FEBS letters.
[27] J. Weil,et al. Role of cyclic adenosine monophosphate in the induction of endothelial barrier properties , 1989, Journal of cellular physiology.
[28] M. Colledge,et al. AKAPs: from structure to function. , 1999, Trends in cell biology.
[29] F. Curry,et al. Dominant role of cAMP in regulation of microvessel permeability. , 2000, American journal of physiology. Heart and circulatory physiology.
[30] F. Luscinskas,et al. ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-alpha-activated vascular endothelium under flow. , 2005, Blood.
[31] C. Doerschuk,et al. Neutrophil-Induced Changes in the Biomechanical Properties of Endothelial Cells: Roles of ICAM-1 and Reactive Oxygen Species1 , 2000, The Journal of Immunology.
[32] S. Cunningham,et al. JAM2 interacts with alpha4beta1. Facilitation by JAM3. , 2002, The Journal of biological chemistry.
[33] B. M. Koster,et al. Inhibition of interleukin-8-activated human neutrophil chemotaxis by thapsigargin in a calcium- and cyclic AMP-dependent way. , 2000, Biochemical pharmacology.
[34] M. Corada,et al. Epac1 regulates integrity of endothelial cell junctions through VE‐cadherin , 2005, FEBS letters.
[35] S. Nourshargh,et al. Divergent Effects of Platelet-Endothelial Cell Adhesion Molecule-1 and β3 Integrin Blockade on Leukocyte Transmigration In Vivo1 , 2000, The Journal of Immunology.
[36] A M Graybiel,et al. A family of cAMP-binding proteins that directly activate Rap1. , 1998, Science.
[37] Joanna C. Porter,et al. LFA-1-induced T cell migration on ICAM-1 involves regulation of MLCK-mediated attachment and ROCK-dependent detachment , 2003, Journal of Cell Science.
[38] J. Bos. Linking Rap to cell adhesion. , 2005, Current opinion in cell biology.
[39] B. Eickholt,et al. Sema3A-induced growth-cone collapse is mediated by Rac1 amino acids 17–32 , 1999, Current Biology.
[40] M. Pfaff,et al. Integrin affinity modulation. , 1998, Trends in cell biology.
[41] N. Rocamora,et al. Ezrin links syndecan-2 to the cytoskeleton. , 2000, Journal of cell science.
[42] H. Davis,et al. Regulation of endothelial cell gap formation and barrier dysfunction: Role of myosin light chain phosphorylation , 1995, Journal of cellular physiology.
[43] E. Crockett-Torabi,et al. Selectins and mechanisms of signal transduction , 1998, Journal of leukocyte biology.
[44] C. Voermans,et al. Migration of Human Hematopoietic Progenitor Cells Across Bone Marrow Endothelium Is Regulated by Vascular Endothelial Cadherin1 , 2002, The Journal of Immunology.
[45] J. Scott. Cyclic nucleotide-dependent protein kinases. , 1991, Pharmacology & therapeutics.
[46] N. Minato,et al. Rap1 Functions as a Key Regulator of T-Cell and Antigen-Presenting Cell Interactions and Modulates T-Cell Responses , 2002, Molecular and Cellular Biology.
[47] J. Shute,et al. Plasminogen Activator Inhibitor-1 Supports IL-8-Mediated Neutrophil Transendothelial Migration by Inhibition of the Constitutive Shedding of Endothelial IL-8/Heparan Sulfate/Syndecan-1 Complexes1 , 2003, The Journal of Immunology.
[48] D. Underwood,et al. New phosphodiesterase inhibitors as therapeutics for the treatment of chronic lung disease. , 2000, Current opinion in pulmonary medicine.
[49] W. Birchmeier,et al. Rap1 Regulates the Formation of E-Cadherin-Based Cell-Cell Contacts , 2004, Molecular and Cellular Biology.
[50] K. Kaibuchi,et al. Rho-Kinase Phosphorylates COOH-terminal Threonines of Ezrin/Radixin/Moesin (ERM) Proteins and Regulates Their Head-to-Tail Association , 1998, The Journal of cell biology.
[51] B. Geiger,et al. Cyclic changes in the organization of cell adhesions and the associated cytoskeleton, induced by stimulation of tyrosine phosphorylation in bovine aortic endothelial cells. , 1997, Journal of cell science.
[52] R. Alon,et al. The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice. , 2000, Blood.
[53] J. Bos,et al. Epac-selective cAMP Analog 8-pCPT-2′-O-Me-cAMP as a Stimulus for Ca2+-induced Ca2+ Release and Exocytosis in Pancreatic β-Cells* , 2003, The Journal of Biological Chemistry.
[54] N. Oppenheimer-Marks,et al. Inhibition of the transendothelial migration of human T lymphocytes by prostaglandin E2. , 1994, Journal of immunology.
[55] J. Massagué,et al. Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-beta receptor system. , 1991, Cell.
[56] A. Bretscher. Regulation of cortical structure by the ezrin-radixin-moesin protein family. , 1999, Current opinion in cell biology.
[57] P. Janmey,et al. Changes in the biomechanical properties of neutrophils and endothelial cells during adhesion. , 2001, Blood.
[58] Bastien Hermant,et al. Identification of Proteases Involved in the Proteolysis of Vascular Endothelium Cadherin during Neutrophil Transmigration* , 2003, The Journal of Biological Chemistry.
[59] M. Auer,et al. Transcytosis and Surface Presentation of IL-8 by Venular Endothelial Cells , 1997, Cell.
[60] P. Wilkinson,et al. Studies of chemotactic factor-induced polarity in human neutrophils. Lipid mobility, receptor distribution and the time-sequence of polarization. , 1991, Journal of cell science.
[61] O. Weiner,et al. Regulation of cell polarity during eukaryotic chemotaxis: the chemotactic compass. , 2002, Current opinion in cell biology.
[62] Courtney M. Lappas,et al. Activation of A2A adenosine receptors inhibits expression of α4/β1 integrin (very late antigen‐4) on stimulated human neutrophils , 2004 .
[63] J. Elferink,et al. The role of cyclic nucleotides in neutrophil migration. , 1996, General pharmacology.
[64] R. Pardi,et al. Feedback modulation of ligand-engaged alpha L/beta 2 leukocyte integrin (LFA-1) by cyclic AMP-dependent protein kinase. , 1996, Journal of immunology.
[65] M. Yáñez-Mó,et al. Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis. , 1999, Journal of immunology.
[66] C. Turner. Paxillin and focal adhesion signalling , 2000, Nature Cell Biology.
[67] Y. Takai,et al. Regulation of E-cadherin Endocytosis by Nectin through Afadin, Rap1, and p120ctn*[boxs] , 2005, Journal of Biological Chemistry.
[68] Sue Goo Rhee,et al. Hydrogen Peroxide: A Key Messenger That Modulates Protein Phosphorylation Through Cysteine Oxidation , 2000, Science's STKE.
[69] L. Aarden,et al. Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production , 1995, The Journal of experimental medicine.
[70] L. Parise,et al. Relationships between Rap1b, Affinity Modulation of Integrin αIIbβ3, and the Actin Cytoskeleton* , 2002, The Journal of Biological Chemistry.
[71] M. Aurrand-Lions,et al. Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration. , 2002, Blood.
[72] G. Frantz,et al. Vascular Endothelial-Junctional Adhesion Molecule (VE-JAM)/JAM 2 Interacts with T, NK, and Dendritic Cells Through JAM 3 , 2002, The Journal of Immunology.
[73] E. Dejana,et al. In Vitro Degradation of Endothelial Catenins by a Neutrophil Protease , 1998, The Journal of cell biology.
[74] Jia-huai Wang,et al. Structural specializations of immunoglobulin superfamily members for adhesion to integrins and viruses , 1998, Immunological reviews.
[75] F. Luscinskas,et al. Endothelial-dependent Mechanisms Regulate Leukocyte Transmigration: A Process Involving the Proteasome and Disruption of the Vascular Endothelial–Cadherin Complex at Endothelial Cell-to-Cell Junctions , 1997, The Journal of experimental medicine.
[76] J. Elferink,et al. Interaction of cyclic GMP and cyclic AMP during neutrophil migration: involvement of phosphodiesterase type III. , 1998, Biochemical pharmacology.
[77] C. Murdoch,et al. Chemokine receptors and their role in inflammation and infectious diseases. , 2000, Blood.
[78] A. Dubois,et al. Inhibition of PAF-induced expression of CD11b and shedding of L-selectin on human neutrophils and eosinophils by the type IV selective PDE inhibitor, rolipram. , 1997, The European respiratory journal.
[79] A. Zlotnik,et al. Chemokines: a new classification system and their role in immunity. , 2000, Immunity.
[80] A. Malik,et al. Signaling mechanisms regulating endothelial permeability. , 2006, Physiological reviews.
[81] R. Hynes,et al. Differential requirements for alpha4 integrins during fetal and adult hematopoiesis. , 1996, Cell.
[82] J. Pouysségur,et al. Regulation of the actin cytoskeleton by thrombin in human endothelial cells: role of Rho proteins in endothelial barrier function. , 1998, Molecular biology of the cell.
[83] J. Elferink,et al. The role of cyclic AMP and protein kinase A in stimulation of neutrophil migration by endothelins , 1998, Naunyn-Schmiedeberg's Archives of Pharmacology.
[84] E. Dejana,et al. Regulation of cadherin function by Rho and Rac: modulation by junction maturation and cellular context. , 1999, Molecular biology of the cell.
[85] A. Nagler,et al. cAMP-induced PKC activation increases functional CXCR4 expression on human CD34 hematopoietic progenitors , 2005 .
[86] R. Alon,et al. Shear forces promote lymphocyte migration across vascular endothelium bearing apical chemokines , 2001, Nature Immunology.
[87] D. F. Barber,et al. Vav1 Phosphorylation Is Induced by β2 Integrin Engagement on Natural Killer Cells Upstream of Actin Cytoskeleton and Lipid Raft Reorganization , 2003, The Journal of experimental medicine.
[88] H. Dvorak,et al. Neutrophils Emigrate from Venules by a Transendothelial Cell Pathway in Response to FMLP , 1998, The Journal of experimental medicine.
[89] O. Barreiro,et al. Polarization and interaction of adhesion molecules P-selectin glycoprotein ligand 1 and intercellular adhesion molecule 3 with moesin and ezrin in myeloid cells. , 2000, Blood.
[90] K. Fujiwara,et al. Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction , 2002, The Journal of cell biology.
[91] G. Freeman,et al. RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion. , 2004, Developmental cell.
[92] Orion D. Weiner,et al. Leukocytes navigate by compass: roles of PI3Kγ and its lipid products , 2000 .
[93] T. L. Deem,et al. Lymphocyte Migration Through Monolayers of Endothelial Cell Lines Involves VCAM-1 Signaling Via Endothelial Cell NADPH Oxidase1 , 2000, The Journal of Immunology.
[94] K. Katagiri,et al. Regulation of lymphocyte adhesion and migration by the small GTPase Rap1 and its effector molecule, RAPL. , 2004, Immunology letters.
[95] Philip E. Dawson,et al. Presentation of chemokine SDF-1α by fibronectin mediates directed migration of T cells , 2000 .
[96] N. Mochizuki,et al. Cyclic AMP Potentiates Vascular Endothelial Cadherin-Mediated Cell-Cell Contact To Enhance Endothelial Barrier Function through an Epac-Rap1 Signaling Pathway , 2005, Molecular and Cellular Biology.
[97] R. Hynes,et al. Differential Requirements for α4 Integrins during Fetal and Adult Hematopoiesis , 1996, Cell.
[98] J. Small,et al. Modulation of substrate adhesion dynamics via microtubule targeting requires kinesin-1 , 2002, The Journal of cell biology.
[99] H. Lum,et al. Oxidant stress and endothelial cell dysfunction. , 2001, American journal of physiology. Cell physiology.
[100] P. Devreotes,et al. Temporal and spatial regulation of chemotaxis. , 2002, Developmental cell.
[101] R. Alon,et al. Chemokine Stimulation of Lymphocyte α4Integrin Avidity but Not of Leukocyte Function-associated Antigen-1 Avidity to Endothelial Ligands under Shear Flow Requires Cholesterol Membrane Rafts* , 2002, The Journal of Biological Chemistry.
[102] F. Liao,et al. Migration of monocytes across endothelium and passage through extracellular matrix involve separate molecular domains of PECAM-1 , 1995, The Journal of experimental medicine.
[103] R. Valentijn,et al. Systemic capillary leak syndrome. Preventive treatment with terbutaline. , 1988, The Netherlands journal of medicine.
[104] T. Mak,et al. Genetic evidence for functional redundancy of Platelet/Endothelial cell adhesion molecule-1 (PECAM-1): CD31-deficient mice reveal PECAM-1-dependent and PECAM-1-independent functions. , 1999, Journal of immunology.
[105] T. Springer,et al. The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood , 1997, The Journal of experimental medicine.
[106] Erwin G. Van Meir,et al. Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5. , 2001, Gene.
[107] J. van den Born,et al. Differences in sulfation patterns of heparan sulfate derived from human bone marrow and umbilical vein endothelial cells. , 2001, Experimental hematology.
[108] K. Hahn,et al. Localized Rac activation dynamics visualized in living cells. , 2000, Science.
[109] A. Hamann,et al. T helper 1 and T helper 2 cells respond differentially to chemokines. , 1998, Journal of immunology.
[110] F. Huang,et al. PKA inhibits RhoA activation: a protection mechanism against endothelial barrier dysfunction. , 2003, American journal of physiology. Lung cellular and molecular physiology.
[111] C. Dean,et al. Environmental-Dependent Acceleration of a Developmental Switch: The Floral Transition , 2000, Science's STKE.
[112] G. Downey,et al. L-selectin stimulation enhances functional expression of surface CXCR4 in lymphocytes: implications for cellular activation during adhesion and migration. , 2003, Blood.
[113] Jonathan A. Cooper,et al. Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors , 2004, The Journal of cell biology.
[114] G. Amerongen,et al. Endothelial hyperpermeability in vascular leakage. , 2002 .
[115] S. Hemmerich,et al. Vascular Endothelial Junction-associated Molecule, a Novel Member of the Immunoglobulin Superfamily, Is Localized to Intercellular Boundaries of Endothelial Cells* , 2000, The Journal of Biological Chemistry.
[116] Francesco Saverio Tedesco,et al. Endothelial Cell E- and P-Selectin and Vascular Cell Adhesion Molecule-1 Function as Signaling Receptors , 1998, The Journal of cell biology.
[117] A. Ridley,et al. Monocyte Adhesion and Spreading on Human Endothelial Cells Is Dependent on Rho-regulated Receptor Clustering , 1999, The Journal of cell biology.
[118] S. Silverstein,et al. Endothelial cell cytosolic free calcium regulates neutrophil migration across monolayers of endothelial cells , 1993, The Journal of cell biology.
[119] M. Wolin. Interactions of oxidants with vascular signaling systems. , 2000, Arteriosclerosis, thrombosis, and vascular biology.
[120] S I Simon,et al. Neutrophil transendothelial migration is independent of tight junctions and occurs preferentially at tricellular corners. , 1997, Journal of immunology.
[121] E. Dejana,et al. Junctional Adhesion Molecule, a Novel Member of the Immunoglobulin Superfamily That Distributes at Intercellular Junctions and Modulates Monocyte Transmigration , 1998, The Journal of cell biology.
[122] A. Strosberg,et al. Intercellular adhesion molecule 1 activation induces tyrosine phosphorylation of the cytoskeleton-associated protein cortactin in brain microvessel endothelial cells. , 1994, The Journal of biological chemistry.
[123] A. Passaniti,et al. Protein tyrosine phosphatase activity regulates endothelial cell-cell interactions, the paracellular pathway, and capillary tube stability. , 2003, American journal of physiology. Lung cellular and molecular physiology.
[124] A. Wittinghofer,et al. Structure and regulation of the cAMP-binding domains of Epac2 , 2003, Nature Structural Biology.
[125] F. Sánchez‐Madrid,et al. Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathway , 1995, The Journal of cell biology.
[126] J. Nordrehaug,et al. Serotonin is associated with coronary artery disease and cardiac events. , 1999, Circulation.
[127] P. Casey,et al. Rap1 GTPase Inhibits Leukocyte Transmigration by Promoting Endothelial Barrier Function* , 2005, Journal of Biological Chemistry.
[128] S. Døskeland,et al. A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK , 2002, Nature Cell Biology.
[129] N. Hogg,et al. Signaling Through Integrin LFA-1 Leads to Filamentous Actin Polymerization and Remodeling, Resulting in Enhanced T Cell Adhesion1 , 2002, The Journal of Immunology.
[130] H. Petty,et al. Lipid raft compartmentalization of urokinase receptor signaling in human neutrophils. , 2004, American journal of respiratory cell and molecular biology.
[131] F. Luscinskas,et al. Reduced expression of junctional adhesion molecule and platelet/endothelial cell adhesion molecule-1 (CD31) at human vascular endothelial junctions by cytokines tumor necrosis factor-alpha plus interferon-gamma Does not reduce leukocyte transmigration under flow. , 2001, The American journal of pathology.
[132] P. Hordijk,et al. Activation of Rhoa and ROCK are essential for detachment of migrating leukocytes. , 2001, Molecular biology of the cell.
[133] W. Kiosses,et al. Spatial restriction of α4 integrin phosphorylation regulates lamellipodial stability and α4β1-dependent cell migration , 2003, The Journal of cell biology.
[134] P. Libby,et al. Prostaglandin E2 Suppresses Chemokine Production in Human Macrophages through the EP4 Receptor* , 2002, The Journal of Biological Chemistry.
[135] C. Doerschuk,et al. The signaling pathways induced by neutrophil-endothelial cell adhesion. , 2002, Antioxidants & redox signaling.
[136] J. Harlan,et al. Requirement for RhoA Kinase Activation in Leukocyte De-Adhesion1 , 2002, The Journal of Immunology.
[137] S. Colgan,et al. Role of VASP in reestablishment of epithelial tight junction assembly after Ca2+ switch. , 2002, American journal of physiology. Cell physiology.
[138] A. Verin,et al. Regulation of endothelial barrier function by the cAMP-dependent protein kinase. , 2000, Endothelium : journal of endothelial cell research.
[139] F. Liao,et al. Soluble Domain 1 of Platelet–Endothelial Cell Adhesion Molecule (PECAM) Is Sufficient to Block Transendothelial Migration In Vitro and In Vivo , 1997, The Journal of experimental medicine.
[140] M. Woolkalís,et al. SHP2 Association with VE-Cadherin Complexes in Human Endothelial Cells Is Regulated by Thrombin* , 2000, The Journal of Biological Chemistry.
[141] A. Vaheri,et al. Association of Ezrin with Intercellular Adhesion Molecule-1 and -2 (ICAM-1 and ICAM-2) , 1998, The Journal of Biological Chemistry.
[142] D. Warltier,et al. Antibody to platelet/endothelial cell adhesion molecule-1 reduces myocardial infarct size in a rat model of ischemia-reperfusion injury. , 1996, Circulation.
[143] M. Houslay,et al. PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization. , 2003, The Biochemical journal.
[144] V. Bennett,et al. Adducin Is an In Vivo Substrate for Protein Kinase C: Phosphorylation in the MARCKS-related Domain Inhibits Activity in Promoting Spectrin–Actin Complexes and Occurs in Many Cells, Including Dendritic Spines of Neurons , 1998, The Journal of cell biology.
[145] A. Verin,et al. Role of cAMP-dependent protein kinase A activity in endothelial cell cytoskeleton rearrangement. , 2001, American journal of physiology. Lung cellular and molecular physiology.
[146] I S Zeelenberg,et al. Retention of CXCR4 in the endoplasmic reticulum blocks dissemination of a T cell hybridoma. , 2001, The Journal of clinical investigation.
[147] F. Sánchez‐Madrid,et al. The two poles of the lymphocyte: specialized cell compartments for migration and recruitment. , 1998, Cell adhesion and communication.
[148] J. Massagué,et al. Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system , 1991, Cell.
[149] M. Aurrand-Lions,et al. Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members. , 2001, Blood.
[150] Keith Burridge,et al. RhoA is required for monocyte tail retraction during transendothelial migration , 2001, The Journal of cell biology.
[151] A. Somlyo,et al. Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. , 2003, Physiological reviews.
[152] N. Mochizuki,et al. MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion. , 2005, Molecular biology of the cell.
[153] C. Voermans,et al. The C-terminal Domain of Rac1 Contains Two Motifs That Control Targeting and Signaling Specificity* , 2003, Journal of Biological Chemistry.
[154] W. Muller,et al. Monoclonal antibody to murine PECAM-1 (CD31) blocks acute inflammation in vivo , 1994, The Journal of experimental medicine.
[155] F. Breviario,et al. Leukocyte-endothelial cell adhesive receptors. , 1994, Clinical and experimental rheumatology.
[156] I. Gurubhagavatula,et al. Antibodies Against the First Ig-Like Domain of Human Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Inhibit PECAM-1-Dependent Homophilic Adhesion Block In Vivo Neutrophil Recruitment1 , 2000, The Journal of Immunology.
[157] F. Sánchez‐Madrid,et al. Moesin Interacts with the Cytoplasmic Region of Intercellular Adhesion Molecule-3 and Is Redistributed to the Uropod of T Lymphocytes during Cell Polarization , 1997, The Journal of cell biology.
[158] K. Taskén,et al. Specificity in the cAMP/PKA signaling pathway. differential expression, regulation, and subcellular localization of subunits of PKA. , 2000, Frontiers in bioscience : a journal and virtual library.
[159] E. Butcher,et al. Elevation of Intracellular cAMP Inhibits RhoA Activation and Integrin-dependent Leukocyte Adhesion Induced by Chemoattractants* , 1997, The Journal of Biological Chemistry.
[160] C. Rüegg,et al. Prostaglandin E2 Promotes Integrin αVβ3-dependent Endothelial Cell Adhesion, Rac-activation, and Spreading through cAMP/PKA-dependent Signaling* , 2002, The Journal of Biological Chemistry.
[161] S Esser,et al. Cell confluence regulates tyrosine phosphorylation of adherens junction components in endothelial cells. , 1997, Journal of cell science.
[162] T. Tsuruo,et al. Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow , 2003, The Journal of cell biology.
[163] E. Butcher. Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity , 1991, Cell.
[164] L. Audoly,et al. The role of prostaglandin E2 receptors in the pathogenesis of rheumatoid arthritis. , 2002, The Journal of clinical investigation.
[165] K. Burridge,et al. Leukocyte transendothelial migration: orchestrating the underlying molecular machinery. , 2001, Current Opinion in Cell Biology.
[166] D. Vestweber,et al. Mechanisms that regulate the function of the selectins and their ligands. , 1999, Physiological reviews.
[167] V. V. van Hinsbergh,et al. Role of RhoA and Rho kinase in lysophosphatidic acid-induced endothelial barrier dysfunction. , 2000, Arteriosclerosis, thrombosis, and vascular biology.
[168] Wayne F. Patton,et al. H2O2‐induced filamin redistribution in endothelial cells is modulated by the cyclic AMP‐dependent protein kinase pathway , 1997, Journal of cellular physiology.
[169] C. Derian,et al. Inhibition of chemotactic peptide-induced neutrophil adhesion to vascular endothelium by cAMP modulators. , 1995, Journal of immunology.
[170] J. Alexander,et al. Redox regulation of endothelial barrier integrity. , 2001, American journal of physiology. Lung cellular and molecular physiology.
[171] María Yáñez-Mó,et al. Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes , 2002, The Journal of cell biology.
[172] B. Levi,et al. Role of vasodilator‐stimulated phosphoprotein in protein kinase A‐induced changes in endothelial junctional permeability , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[173] M. Laato,et al. Suppression of Syndecan-1 Expression in Endothelial Cells by Tumor Necrosis Factor-α* , 1996, The Journal of Biological Chemistry.
[174] J. Parsons,et al. Focal adhesion kinase: the first ten years , 2003, Journal of Cell Science.
[175] C. Voermans,et al. Leukocyte-Endothelium Interaction Promotes SDF-1-dependent Polarization of CXCR4* , 2003, Journal of Biological Chemistry.
[176] A. Bugrim. Regulation of Ca2+ release by cAMP-dependent protein kinase. A mechanism for agonist-specific calcium signaling? , 1999, Cell calcium.
[177] T. Springer,et al. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) , 1996, The Journal of experimental medicine.
[178] J. Harlan,et al. The GTPase Rap1 Regulates Phorbol 12-Myristate 13-Acetate-stimulated but Not Ligand-induced β1Integrin-dependent Leukocyte Adhesion* , 2002, The Journal of Biological Chemistry.
[179] C. Parent,et al. Localization of the G Protein βγ Complex in Living Cells During Chemotaxis , 2000 .
[180] C. Figdor,et al. Avidity regulation of integrins: the driving force in leukocyte adhesion. , 2000, Current opinion in cell biology.
[181] F. Luscinskas,et al. Monocytes Induce Reversible Focal Changes in Vascular Endothelial Cadherin Complex during Transendothelial Migration under Flow , 2000, The Journal of cell biology.
[182] H. DeLisser,et al. Neutrophil platelet endothelial cell adhesion molecule-1 participates in neutrophil recruitment at inflammatory sites and is down-regulated after leukocyte extravasation. , 1997, Journal of immunology.
[183] H. Gradin,et al. Regulation of Microtubule Dynamics by Extracellular Signals: cAMP-dependent Protein Kinase Switches Off the Activity of Oncoprotein 18 in Intact Cells , 1998, The Journal of cell biology.
[184] F. Sánchez‐Madrid,et al. Polarization of Chemokine Receptors to the Leading Edge during Lymphocyte Chemotaxis , 1997, The Journal of experimental medicine.
[185] A. Hall,et al. Rho GTPases and the actin cytoskeleton. , 1998, Science.
[186] S. Simon,et al. Roles of neutrophil beta 2 integrins in kinetics of bacteremia, extravasation, and tick acquisition of Anaplasma phagocytophila in mice. , 2003, Blood.
[187] Frits Michiels,et al. Matrix-dependent Tiam1/Rac Signaling in Epithelial Cells Promotes Either Cell–Cell Adhesion or Cell Migration and Is Regulated by Phosphatidylinositol 3-Kinase , 1998, The Journal of cell biology.
[188] K. Hahn,et al. Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI. , 2002, Nature Reviews Molecular Cell Biology.
[189] A. M. Lefer,et al. Blockade of platelet endothelial cell adhesion molecule-1 protects against myocardial ischemia and reperfusion injury in cats. , 1996, Journal of immunology.
[190] P. Singhal,et al. Vasoactive agents modulate migration of monocytes across glomerular endothelial cells. , 2000, Journal of investigative medicine : the official publication of the American Federation for Clinical Research.
[191] Y. Samstag,et al. Actin cytoskeletal dynamics in T lymphocyte activation and migration , 2003, Journal of leukocyte biology.
[192] John G. Collard,et al. Activation of RhoA by Thrombin in Endothelial Hyperpermeability: Role of Rho Kinase and Protein Tyrosine Kinases , 2000, Circulation research.
[193] F. Liao,et al. Transgenic mice expressing different levels of soluble platelet/endothelial cell adhesion molecule-IgG display distinct inflammatory phenotypes. , 1999, Journal of immunology.
[194] M. Ticchioni,et al. CD99 (E2) up-regulates alpha4beta1-dependent T cell adhesion to inflamed vascular endothelium under flow conditions. , 2000, European journal of immunology.
[195] T. Springer. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm , 1994, Cell.
[196] T. Lincoln,et al. Phosphorylation of mammalian myosin light chain kinases by the catalytic subunit of cyclic AMP-dependent protein kinase and by cyclic GMP-dependent protein kinase. , 1984, The Journal of biological chemistry.
[197] A. Strosberg,et al. ICAM-1 signaling pathways associated with Rho activation in microvascular brain endothelial cells. , 1998, Journal of immunology.
[198] C. Weber. Novel mechanistic concepts for the control of leukocyte transmigration: specialization of integrins, chemokines, and junctional molecules , 2002, Journal of Molecular Medicine.
[199] T. Mcclanahan,et al. Involvement of chemokine receptors in breast cancer metastasis , 2001, Nature.
[200] J. Piette,et al. Systemic capillary leak syndrome: report on 13 patients with special focus on course and treatment. , 1997, The American journal of medicine.
[201] B. Ozanne,et al. Essential functions of ezrin in maintenance of cell shape and lamellipodial extension in normal and transformed fibroblasts , 1997, Current Biology.
[202] A. Gautreau,et al. Ezrin regulates E-cadherin-dependent adherens junction assembly through Rac1 activation. , 2003, Molecular biology of the cell.
[203] C. Voermans,et al. Adhesion Molecules Involved in Transendothelial Migration of Human Hematopoietic Progenitor Cells , 2000, Stem cells.
[204] R. Alon,et al. The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flow. , 1999, The Journal of clinical investigation.
[205] T. Mayadas,et al. Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase. , 2005, Blood.
[206] S. Nourshargh,et al. An anti-platelet-endothelial cell adhesion molecule-1 antibody inhibits leukocyte extravasation from mesenteric microvessels in vivo by blocking the passage through the basement membrane , 1996, The Journal of experimental medicine.
[207] A. Wittinghofer,et al. Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2. , 2003, Biochimica et biophysica acta.
[208] Asma Nusrat,et al. Leukocyte transendothelial migration: a junctional affair. , 2002, Seminars in immunology.
[209] T. Springer,et al. Sequential regulation of alpha 4 beta 1 and alpha 5 beta 1 integrin avidity by CC chemokines in monocytes: implications for transendothelial chemotaxis , 1996, The Journal of cell biology.
[210] P. Hordijk,et al. VCAM-1-mediated Rac signaling controls endothelial cell-cell contacts and leukocyte transmigration. , 2003, American journal of physiology. Cell physiology.
[211] F. Luscinskas,et al. Neutrophils from MMP‐9‐ or neutrophil elastase‐deficient mice show no defect in transendothelial migration under flow in vitro , 2002, Journal of leukocyte biology.
[212] S. Cunningham,et al. Cloning of Human Junctional Adhesion Molecule 3 (JAM3) and Its Identification as the JAM2 Counter-receptor* , 2001, The Journal of Biological Chemistry.
[213] J. Pablos,et al. Synoviocyte-Derived CXCL12 Is Displayed on Endothelium and Induces Angiogenesis in Rheumatoid Arthritis 1 , 2003, The Journal of Immunology.
[214] L. McIntire,et al. Permeability of human endothelial monolayers: effect of vasoactive agonists and cAMP. , 1989, Journal of applied physiology.
[215] S. Thom,et al. Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. , 1993, Science.
[216] J. Bos,et al. Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the β2-adrenergic receptor , 2003, The Journal of cell biology.
[217] C M Doerschuk,et al. The p38 Mitogen-Activated Protein Kinase Mediates Cytoskeletal Remodeling in Pulmonary Microvascular Endothelial Cells Upon Intracellular Adhesion Molecule-1 Ligation1 , 2001, The Journal of Immunology.
[218] Daniel Kalman,et al. Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis , 2003, The Journal of cell biology.
[219] Elisabetta Dejana,et al. Endothelial cell–cell junctions: happy together , 2004, Nature Reviews Molecular Cell Biology.
[220] D. Taub,et al. CXCR4 Function Requires Membrane Cholesterol: Implications for HIV Infection , 2002, The Journal of Immunology.
[221] V. O’Donnell,et al. Expression of phagocyte NADPH oxidase components in human endothelial cells. , 1996, The American journal of physiology.
[222] C. Parent,et al. Localization of the G protein betagamma complex in living cells during chemotaxis. , 2000, Science.
[223] N. Mochizuki,et al. Local Activation of Rap1 Contributes to Directional Vascular Endothelial Cell Migration Accompanied by Extension of Microtubules on Which RAPL, a Rap1-associating Molecule, Localizes* , 2005, Journal of Biological Chemistry.
[224] John G. Collard,et al. Reactive oxygen species mediate Rac-induced loss of cell-cell adhesion in primary human endothelial cells. , 2002, Journal of cell science.
[225] N. Mochizuki,et al. Identification of Fer tyrosine kinase localized on microtubules as a platelet endothelial cell adhesion molecule-1 phosphorylating kinase in vascular endothelial cells. , 2003, Molecular biology of the cell.
[226] J. Beavo,et al. Cyclic nucleotide research — still expanding after half a century , 2002, Nature Reviews Molecular Cell Biology.
[227] M. Matsuda,et al. Involvement of the c-Src-Crk-C3G-Rap1 Signaling in the Nectin-induced Activation of Cdc42 and Formation of Adherens Junctions* , 2005, Journal of Biological Chemistry.
[228] K. Katagiri,et al. RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1 , 2003, Nature Immunology.
[229] W. Muller. Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. , 2003, Trends in immunology.
[230] F. Liu,et al. Protein kinase A attenuates endothelial cell barrier dysfunction induced by microtubule disassembly. , 2004, American journal of physiology. Lung cellular and molecular physiology.
[231] A. Issekutz,et al. Role of ICAM‐1 and ICAM‐2 and alternate CD11/CD18 ligands in neutrophil transendothelial migration , 1999, Journal of leukocyte biology.
[232] D. Rimm,et al. PECAM-1 (CD31) functions as a reservoir for and a modulator of tyrosine-phosphorylated beta-catenin. , 1999, Journal of cell science.
[233] A. Shah,et al. Intracellular Localization and Preassembly of the NADPH Oxidase Complex in Cultured Endothelial Cells* , 2002, The Journal of Biological Chemistry.
[234] A. Sonnenberg,et al. The cAMP-Epac-Rap1 Pathway Regulates Cell Spreading and Cell Adhesion to Laminin-5 through the α3β1 Integrin but Not the α6β4 Integrin* , 2004, Journal of Biological Chemistry.
[235] P. Devreotes,et al. Eukaryotic Chemotaxis: Distinctions between Directional Sensing and Polarization* , 2003, Journal of Biological Chemistry.
[236] M. Ticchioni,et al. CD99 (E2) up‐regulates α 4β 1‐dependent T cell adhesion to inflamed vascular endothelium under flow conditions , 2000 .
[237] Y. Sharief,et al. Asymmetrical protein kinase A activity establishes neutrophil cytoskeletal polarity and enables chemotaxis , 2005, Journal of leukocyte biology.
[238] H. Barth,et al. cAMP protects endothelial barrier functions by preventing Rac-1 inhibition. , 2004, American journal of physiology. Heart and circulatory physiology.
[239] J. Loureiro,et al. Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration. , 2003, Annual review of cell and developmental biology.
[240] O. Barreiro,et al. Interactive protrusive structures during leukocyte adhesion and transendothelial migration. , 2004, Frontiers in bioscience : a journal and virtual library.
[241] K. Ley,et al. L‐selectin: mechanisms and physiological significance of ectodomain cleavage , 2005, Journal of cellular and molecular medicine.
[242] R. Stancou,et al. Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. , 1996, The EMBO journal.
[243] K. Preissner,et al. Leukocyte trans-endothelial migration: JAMs add new pieces to the puzzle , 2003, Thrombosis and Haemostasis.
[244] S. Silverstein,et al. Stimulated neutrophils induce myosin light chain phosphorylation and isometric tension in endothelial cells. , 1997, The American journal of physiology.
[245] H. Saito,et al. Endothelial myosin light chain kinase regulates neutrophil migration across human umbilical vein endothelial cell monolayer. , 1998, Journal of immunology.
[246] T. Bivona,et al. Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion , 2004, The Journal of cell biology.
[247] H. Lum,et al. Expression of PKA inhibitor ( PKI) gene abolishes cAMPmediated protection to endothelial barrier dysfunction. , 1999, American journal of physiology. Cell physiology.
[248] D. Phillips,et al. PECAM-1 is required for transendothelial migration of leukocytes , 1993, The Journal of experimental medicine.
[249] J. Wilcox,et al. Upregulation of Nox‐Based NAD(P)H Oxidases in Restenosis After Carotid Injury , 2002, Arteriosclerosis, thrombosis, and vascular biology.
[250] Samuel L. Jones. Protein kinase A regulates β2 integrin avidity in neutrophils , 2002, Journal of Leukocyte Biology.
[251] W. R. Taylor,et al. Superoxide Production and Expression of Nox Family Proteins in Human Atherosclerosis , 2002, Circulation.
[252] G. Guillemette,et al. Permeability of endothelial monolayers to albumin is increased by bradykinin and inhibited by prostaglandins. , 2001, American journal of physiology. Lung cellular and molecular physiology.
[253] C. Figdor,et al. The Small GTPase Rap1 Is Required for Mn2+- and Antibody-induced LFA-1- and VLA-4-mediated Cell Adhesion* , 2002, The Journal of Biological Chemistry.
[254] T. Andersson,et al. Beta 2 integrin engagement triggers actin polymerization and phosphatidylinositol trisphosphate formation in non-adherent human neutrophils , 1993, The Journal of cell biology.
[255] S. Walsh,et al. Human junction adhesion molecule regulates tight junction resealing in epithelia. , 2000, Journal of cell science.