Specific gating of the early somatosensory evoked potentials during active movement.

The gating effect of self-paced rapid flexion movements of the fingers on the early somatosensory evoked potentials following electrical stimulation of the median nerve at the wrist was studied in normal volunteers. Triggering of the median nerve stimulation by the EMG signals with a delay of 100 msec showed that the slow positive wave of the movement-associated potential was not directly responsible for the SEP amplitude variations observed. The nerve action potential at Erb's point as well as far-field components P9 and P11 were unchanged by the active movements. Far-field components P13-P14, which are presumably generated in the medial lemniscus, were not significantly modified. An enhancing effect on the widespread N18 component was found, which is in favour of a subcortical gating process. The parietal component N20 was unchanged by active movement interference whereas the frontal P22 component showed a marked suppression. A fronto-parietal dissociation was thus disclosed which could be in favour of separate cortical generators in the debate on the origin of SEP components. An important gating effect was observed on parietal P27 and frontal N30 components, the latter being considerably reduced in amplitude. The parietal P45 component showed no significant alteration. Each component of the early SEPs was thus distinctly influenced by the gating process during active movement interference.

[1]  R. Cooper,et al.  Inhibition of cortical evoked potentials and sensation by self-initiated movement in man , 1975, Nature.

[2]  C. Ghez,et al.  Inhibition of afferent transmission in cuneate nucleus during voluntary movement in the cat. , 1972, Brain research.

[3]  W C Wiederholt,et al.  Short-latency somatosensory evoked potentials. , 1978, Archives of neurology.

[4]  S. Jones,et al.  An 'interference" approach to the study of somatosensory evoked potentials in man. , 1981, Electroencephalography and clinical neurophysiology.

[5]  E Grünewald-Zuberbier,et al.  Movement‐Associated Potentials and Motor Control Report of the EPIC VI Motor Panel , 1984, Annals of the New York Academy of Sciences.

[6]  C. C. Boylls,et al.  Velocity-dependent suppression of somatosensory evoked potentials during movement. , 1985, Electroencephalography and clinical neurophysiology.

[7]  F Mauguière,et al.  Astereognosis and dissociated loss of frontal or parietal components of somatosensory evoked potentials in hemispheric lesions. Detailed correlations with clinical signs and computerized tomographic scanning. , 1983, Brain : a journal of neurology.

[8]  G Cheron,et al.  Central somatosensory conduction in man: neural generators and interpeak latencies of the far-field components recorded from neck and right or left scalp and earlobes. , 1980, Electroencephalography and clinical neurophysiology.

[9]  R. Malenka,et al.  Velocity-dependent suppression of cutaneous sensitivity during movement , 1982, Experimental Neurology.

[10]  S. Williamson.  MAGNETIC LOCATION OF CORTICAL ACTIVITY * , 1980 .

[11]  M. Coulmance,et al.  Modifications des potentiels evoques corticaux somesthesiques durant des mouvements actifs et passifs chez l'homme , 1972 .

[12]  G Cheron,et al.  Somatosensory evoked potentials to finger stimulation in healthy octogenarians and in young adults: wave forms, scalp topography and transit times of parietal and frontal components. , 1980, Electroencephalography and clinical neurophysiology.

[13]  S. Jones,et al.  Scalp topography of human somatosensory evoked potentials: the effect of interfering tactile stimulation applied to the hand. , 1984, Electroencephalography and clinical neurophysiology.

[14]  Donald J. Woodward,et al.  Modulation of sensory responsiveness of single somatosensory cortical cells during movement and arousal behaviors , 1981, Experimental Neurology.

[15]  F. Mauguière,et al.  Early somatosensory evoked potentials in thalamo-cortical lesions of the lemniscal pathways in humans. , 1982, Advances in neurology.

[16]  A. Starr,et al.  Vibration and muscle contraction affect somatosensory evoked potentials , 1985, Neurology.

[17]  G. Cheron,et al.  SOMATOSENSORY EVOKED POTENTIALS IN MAN: SUBCORTICAL AKD CORTICAL COMPONENTS AND THEIR NEURAL BASIS * , 1980 .

[18]  Y. Toyokura,et al.  The initial positive component of the scalp-recorded somatosensory evoked potential in normal subjects and in patients with neurological disorders. , 1978, Electroencephalography and clinical neurophysiology.

[19]  J. Rothwell,et al.  Gating of somatosensory evoked potentials during different kinds of movement in man. , 1981, Brain : a journal of neurology.

[20]  R Kakigi,et al.  Influence of concurrent tactile stimulation on somatosensory evoked potentials following posterior tibial nerve stimulation in man. , 1986, Electroencephalography and clinical neurophysiology.

[21]  J. Desmedt.  Cerebral motor control in man : long loop mechanisms , 1978 .

[22]  A. Wyler,et al.  Somatosensory evoked potentials after removal of somatosensory cortex in man. , 1986, Electroencephalography and Clinical Neurophysiology.

[23]  V. Hömberg,et al.  Cerebral potentials during skilled slow positioning movements , 1981, Biological Psychology.

[24]  A. Towe,et al.  Cortical inhibition of neurons in dorsal column nuclei of cat. , 1961, Journal of neurophysiology.

[25]  D. Giblin,et al.  SOMATOSENSORY EVOKED POTENTIALS IN HEALTHY SUBJECTS AND IN PATIENTS WITH LESIONS OF THE NERVOUS SYSTEM * † , 1964, Annals of the New York Academy of Sciences.

[26]  G. Grünewald,et al.  14 Cerebral Potentials During Voluntary Ramp Movements in Aiming Tasks , 1983 .

[27]  G. Cheron,et al.  Non-cephalic reference recording of early somatosensory potentials to finger stimulation in adult or aging normal man: differentiation of widespread N18 and contralateral N20 from the prerolandic P22 and N30 components. , 1981, Electroencephalography and clinical neurophysiology.

[28]  P. Hazemann,et al.  Effect of voluntary self-paced movements upon auditory and somatosensory evoked potentials in man. , 1975, Electroencephalography and clinical neurophysiology.

[29]  J. Tanji,et al.  Reflex and intended responses in motor cortex pyramidal tract neurons of monkey. , 1976, Journal of neurophysiology.

[30]  Jones Eg,et al.  The nature of the afferent pathways conveying short-latency inputs to primate motor cortex. , 1983 .

[31]  R Kakigi,et al.  Effects on median nerve SEPs of tactile stimulation applied to adjacent and remote areas of the body surface. , 1985, Electroencephalography and clinical neurophysiology.

[32]  J. D. Coulter,et al.  Sensory transmission through lemniscal pathway during voluntary movement in the cat. , 1974, Journal of neurophysiology.

[33]  R. Lee,et al.  Modification of the human somatosensory evoked response during voluntary movement. , 1974, Electroencephalography and clinical neurophysiology.