α1-Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients
暂无分享,去创建一个
M. Griese | P. Latzin | D. Hartl | M. Kappler | T. Bernhardt | K. Weckerle | T. Heinzlmaier | Dominik Hartl | Matthias Griese | Philipp Latzin
[1] M. Keogan,et al. Safety and Efficacy of Recombinant Alpha1‐Antitrypsin Therapy in Cystic Fibrosis , 2006, Pediatric pulmonology.
[2] M. Griese,et al. Optimum peripheral drug deposition in patients with cystic fibrosis. , 2005, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.
[3] S. Janciauskiene,et al. Prolastin, a pharmaceutical preparation of purified human α1-antitrypsin, blocks endotoxin-mediated cytokine release , 2005, Respiratory research.
[4] H. Magnussen,et al. Cellular profiles of induced sputum in children with stable cystic fibrosis: comparison with BAL , 2003, European Respiratory Journal.
[5] G. Scheuch,et al. Peripheral deposition of α1‐protease inhibitor using commercial inhalation devices , 2003, European Respiratory Journal.
[6] F. Lottspeich,et al. Limited proteolysis of surfactant protein D causes a loss of its calcium-dependent lectin functions. , 2003, Biochimica et biophysica acta.
[7] M. Griese,et al. Proteolysis of Surfactant Protein D by Cystic Fibrosis Relevant Proteases , 2003, Lung.
[8] M. Konstan,et al. Inflammatory mediators in CF patients. , 2002, Methods in molecular medicine.
[9] N. Alexis,et al. Sputum phagocytes from healthy individuals are functional and activated: a flow cytometric comparison with cells in bronchoalveolar lavage and peripheral blood. , 2000, Clinical immunology.
[10] J. Heesemann,et al. Specific and Rapid Detection by Fluorescent In Situ Hybridization of Bacteria in Clinical Samples Obtained from Cystic Fibrosis Patients , 2000, Journal of Clinical Microbiology.
[11] M. Ballmann,et al. Fractional analysis of bronchoalveolar lavage fluid cytology in cystic fibrosis patients with normal lung function. Bronchoalveolar lavage for the evaluation of anti-inflammatory treatment (BEAT) study group. , 2000, The European respiratory journal.
[12] A. Cantin,et al. Aerosolized prolastin suppresses bacterial proliferation in a model of chronic Pseudomonas aeruginosa lung infection. , 1999, American journal of respiratory and critical care medicine.
[13] M. Konstan,et al. Altered respiratory epithelial cell cytokine production in cystic fibrosis. , 1999, The Journal of allergy and clinical immunology.
[14] Melvin Berger,et al. Current understanding of the inflammatory process in cystic fibrosis: Onset and etiology , 1997, Pediatric pulmonology.
[15] E. Allen. Opportunities for the Use of Aerosolized α1-Antitrypsin for the Treatment of Cystic Fibrosis , 1996 .
[16] E. Allen. Opportunities for the use of aerosolized alpha 1-antitrypsin for the treatment of cystic fibrosis. , 1996, Chest.
[17] C. Boudier,et al. Cleavage of lymphocyte surface antigens CD2, CD4, and CD8 by polymorphonuclear leukocyte elastase and cathepsin G in patients with cystic fibrosis. , 1995, Journal of immunology.
[18] P. Birrer. Proteases and antiproteases in cystic fibrosis: pathogenetic considerations and therapeutic strategies. , 1995, Respiration; international review of thoracic diseases.
[19] G. Döring. The role of neutrophil elastase in chronic inflammation. , 1994, American journal of respiratory and critical care medicine.
[20] R. Crystal,et al. Protease-antiprotease imbalance in the lungs of children with cystic fibrosis. , 1994, American journal of respiratory and critical care medicine.
[21] R. Crystal,et al. Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line. , 1992, The Journal of clinical investigation.
[22] K. Havemann,et al. Regulation of neutrophil functions by elastase-generated IgG fragments. , 1992, Archivum immunologiae et therapiae experimentalis.
[23] R. Crystal,et al. Neutrophil accumulation in the lung in alpha 1-antitrypsin deficiency. Spontaneous release of leukotriene B4 by alveolar macrophages. , 1991, The Journal of clinical investigation.
[24] K. Havemann,et al. Inhibition of Neutrophil Chemotaxis by Elastase‐Generated IgG Fragments , 1991, Scandinavian journal of immunology.
[25] R. Crystal,et al. Aerosol α1 -antitrypsin treatment for cystic fibrosis , 1991, The Lancet.
[26] R. Stockley,et al. Effects of human neutrophil elastase and Pseudomonas aeruginosa proteinases on human respiratory epithelium. , 1991, American journal of respiratory cell and molecular biology.
[27] S. Suter,et al. Proteolytic inactivation of alpha 1-proteinase inhibitor in infected bronchial secretions from patients with cystic fibrosis. , 1991, The European respiratory journal.
[28] R. Crystal,et al. Aerosol alpha 1-antitrypsin treatment for cystic fibrosis. , 1991, Lancet.
[29] K. Havemann,et al. Inhibition of neutrophil oxidative burst by elastase-generated IgG fragments. , 1990, Biological chemistry Hoppe-Seyler.
[30] R. Fick,et al. Functional importance of cystic fibrosis immunoglobulin G fragments generated by Pseudomonas aeruginosa elastase. , 1989, The Journal of laboratory and clinical medicine.
[31] D. Dearborn,et al. Complement receptor expression on neutrophils at an inflammatory site, the Pseudomonas-infected lung in cystic fibrosis. , 1989, The Journal of clinical investigation.
[32] S. Suter,et al. Fibronectin-cleaving activity in bronchial secretions of patients with cystic fibrosis. , 1988, The Journal of infectious diseases.
[33] K. Havemann,et al. Neoantigenic group on Fc fragments in rheumatoid arthritis synovial fluids. , 1988, Scandinavian journal of rheumatology. Supplement.
[34] A. Kharazmi,et al. Elastase from polymorphonuclear leucocytes: a regulatory enzyme in immune complex disease. , 1986, Clinical and experimental immunology.
[35] R. Baltimore,et al. IgG proteolytic activity of Pseudomonas aeruginosa in cystic fibrosis. , 1985, The Journal of infectious diseases.
[36] J. Gee,et al. Proteins of the cystic fibrosis respiratory tract. Fragmented immunoglobulin G opsonic antibody causing defective opsonophagocytosis. , 1984, The Journal of clinical investigation.
[37] P. Kimbel. Proteolytic lung damage. , 1980, Chest.
[38] J. Gustafson,et al. Cystic Fibrosis , 2009, Journal of the Iowa Medical Society.