Phenolic Constituents from Fallopia multiflora (Thunberg) Haraldson

Four naphtolic glycosides (1–4), three anthraquinones (5–7), two stilbenes (8-9), one benzyl glycoside (10), and one flavonoid (11) were isolated from the roots of Fallopia multiflora. The new compounds were elucidated to be 6-hydroxymusizin 8-O-α-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (1) and 6-methoxy-3-methyl-1,6,8-trihydroxy-2-naphthoic acid 8-O-β-D-glucopyranoside (3). Compound 3 could be an important marker for chemotaxonomy of F. multiflora. Benzyl gentiobioside (10) was isolated for the first time from the family Polygonaceae.

[1]  H. Kuang,et al.  New Thymoquinol Glycosides and Neuroprotective Dibenzocyclooctane Lignans from the Rattan Stems of Schisandra chinensis , 2016, Chemistry & biodiversity.

[2]  Jing Zhang,et al.  Application of Ultra-High-Performance Liquid Chromatography Coupled with LTQ-Orbitrap Mass Spectrometry for the Qualitative and Quantitative Analysis of Polygonum multiflorum Thumb. and Its Processed Products , 2015, Molecules.

[3]  Nan Zhang,et al.  Two new diphenyl ethers from Acanthopanax senticosus (Rupr. & Maxim.) Harms with PTP1B inhibitory activity , 2015 .

[4]  A. Nwafor,et al.  Phytochemical Identification in the Chloroform Fraction of Aqueous-Methanol Extract of Cnidoscolus aconitifolius Leaves , 2015 .

[5]  Jian Ni,et al.  Traditional usages, botany, phytochemistry, pharmacology and toxicology of Polygonum multiflorum Thunb.: A review , 2014, Journal of Ethnopharmacology.

[6]  Jung-il Kang,et al.  Promotion effect of constituents from the root of Polygonum multiflorum on hair growth. , 2013, Bioorganic & medicinal chemistry letters.

[7]  Yu-Ling Ho,et al.  Quality assessment on Polygoni Multiflori Caulis using HPLC/UV/MS combined with principle component analysis , 2013, Chemistry Central Journal.

[8]  Youhua Xu,et al.  Pre-column incubation followed by fast liquid chromatography analysis for rapid screening of natural methylglyoxal scavengers directly from herbal medicines: case study of Polygonum cuspidatum. , 2013, Journal of chromatography. A.

[9]  G. He,et al.  Characterization of Proanthocyanidins in Stems of Polygonum multiflorum Thunb as Strong Starch Hydrolase Inhibitors , 2013, Molecules.

[10]  H. Fu,et al.  Bioactive compounds from Rumex plants , 2010 .

[11]  Masao Sato,et al.  Furanaphin: a novel naphtho(2,3-c)furan-4(1H)-one derivative from the aphid Aphis spiraecola Patch , 2004 .

[12]  L. Krenn,et al.  Sulfemodin 8-O-beta-D-glucoside, a new sulfated anthraquinone glycoside, and antioxidant phenolic compounds from Rheum emodi. , 2003, Journal of natural products.

[13]  A. Zeeck,et al.  Five naphthalene glycosides from the roots of Rumex patientia. , 2001, Phytochemistry.

[14]  Chun-nan Lin,et al.  Anthraquinone and naphthalene glycosides from Rhamnus nakaharai , 1993 .

[15]  G. Janssen,et al.  Naphthalene glycosides in Cassia senna and Cassia angustifolia. , 1981, Planta medica.

[16]  G. Nonaka,et al.  Studies on Rhubarb (Rhei Rhizoma). IV. Naphthalene Glycosides , 1977 .