The unique chemistry of benzoxaboroles: current and emerging applications in biotechnology and therapeutic treatments.
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[1] Yuting Zhang,et al. Benzoboroxole-functionalized magnetic core/shell microspheres for highly specific enrichment of glycoproteins under physiological conditions. , 2014, Small.
[2] Aurélien Lesnard,et al. First identification of boronic species as novel potential inhibitors of the Staphylococcus aureus NorA efflux pump. , 2014, Journal of medicinal chemistry.
[3] R. Wu,et al. The Active Site Sulfenic Acid Ligand in Nitrile Hydratases Can Function as a Nucleophile , 2014, Journal of the American Chemical Society.
[4] Baorui Liu,et al. The combined effects of size and surface chemistry on the accumulation of boronic acid-rich protein nanoparticles in tumors. , 2014, Biomaterials.
[5] J. Trujillo-Ferrara,et al. Boron-containing acids: preliminary evaluation of acute toxicity and access to the brain determined by Raman scattering spectroscopy. , 2014, Neurotoxicology.
[6] D. Westerberg,et al. Onychomycosis: Current trends in diagnosis and treatment. , 2013, American family physician.
[7] K. Jarnagin,et al. Linking Phenotype to Kinase: Identification of a Novel Benzoxaborole Hinge-Binding Motif for Kinase Inhibition and Development of High-Potency Rho Kinase Inhibitors , 2013, The Journal of Pharmacology and Experimental Therapeutics.
[8] J. Dubuisson,et al. Phenylboronic-acid-modified nanoparticles: potential antiviral therapeutics. , 2013, ACS applied materials & interfaces.
[9] K. Jarnagin,et al. Discovery and structure-activity relationships of 6-(benzoylamino)benzoxaboroles as orally active anti-inflammatory agents. , 2013, Bioorganic & medicinal chemistry letters.
[10] W. Maison,et al. Synthesis of Adamantane‐Based Trimeric Benzoboroxoles , 2013 .
[11] S. Benkovic,et al. Capturing a sulfenic acid with arylboronic acids and benzoxaborole. , 2013, Journal of the American Chemical Society.
[12] Yinan Lin,et al. The synthesis of benzoxaboroles and their applications in medicinal chemistry , 2013, Science China Chemistry.
[13] Michael A. Corsello,et al. Synthesis and Biological Evaluation of Novel Benzoxaboroles as Potential Antimicrobial and Anticancer Agents , 2013 .
[14] H. Taguchi,et al. Biomolecular robotics for chemomechanically driven guest delivery fuelled by intracellular ATP. , 2013, Nature chemistry.
[15] V. Ciaravino,et al. An assessment of the genetic toxicology of novel boron‐containing therapeutic agents , 2013, Environmental and molecular mutagenesis.
[16] M. Cyrański,et al. Benzoxaborolate ligands in group 13 metal complexes , 2013 .
[17] A. K. Yatsimirsky,et al. Substituent effects and pH profiles for stability constants of arylboronic acid diol esters. , 2013, The Journal of organic chemistry.
[18] M. Preobrazhenskaya,et al. Synthesis and study of antibacterial activities of antibacterial glycopeptide antibiotics conjugated with benzoxaboroles. , 2013, Future medicinal chemistry.
[19] P. Ramachandran. Focusing on boron in medicinal chemistry. , 2013, Future medicinal chemistry.
[20] Kate S. Carroll,et al. Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery , 2013, Chemical reviews.
[21] Ronald N. Jones,et al. Potency and Spectrum of Activity of AN3365, a Novel Boron-Containing Protein Synthesis Inhibitor, Tested against Clinical Isolates of Enterobacteriaceae and Nonfermentative Gram-Negative Bacilli , 2013, Antimicrobial Agents and Chemotherapy.
[22] K. Jarnagin,et al. Structure-activity relationships of 6-(aminomethylphenoxy)-benzoxaborole derivatives as anti-inflammatory agent. , 2013, Bioorganic & medicinal chemistry letters.
[23] Y. Kotsuchibashi,et al. Temperature, pH, and Glucose Responsive Gels via Simple Mixing of Boroxole- and Glyco-Based Polymers. , 2013, ACS macro letters.
[24] E. Goldstein,et al. Comparative In Vitro Activities of GSK2251052, a Novel Boron-Containing Leucyl-tRNA Synthetase Inhibitor, against 916 Anaerobic Organisms , 2013, Antimicrobial Agents and Chemotherapy.
[25] P. Kennedy. Clinical features, diagnosis, and treatment of human African trypanosomiasis (sleeping sickness) , 2013, The Lancet Neurology.
[26] J. Nieman,et al. Discovery of a Novel Class of Boron-Based Antibacterials with Activity against Gram-Negative Bacteria , 2013, Antimicrobial Agents and Chemotherapy.
[27] E. Tomecka,et al. Lewis acidity and sugar receptor activity of 3-amino-substituted benzoxaboroles and their ortho-aminomethylphenylboronic acid analogues , 2013 .
[28] Tony T. Huang. Deubiquitinases as a signaling target of oxidative stress , 2012, Cell reports.
[29] S. Benkovic,et al. Examination of the reactivity of benzoxaboroles and related compounds with a cis-diol. , 2012, The Journal of organic chemistry.
[30] K. Jarnagin,et al. Early rapid identification of in vivo rat metabolites of AN6414, a novel boron-containing PDE4 inhibitor by QTRAP LC/MS/MS to support drug discovery. , 2012, Journal of pharmaceutical and biomedical analysis.
[31] John P A Ioannidis,et al. Neglected tropical diseases: survey and geometry of randomised evidence , 2012, BMJ : British Medical Journal.
[32] G. Yeo,et al. Endoplasmic Reticulum Thiol Oxidase Deficiency Leads to Ascorbic Acid Depletion and Noncanonical Scurvy in Mice , 2012, Molecular cell.
[33] K. Jarnagin,et al. Boron‐based phosphodiesterase inhibitors show novel binding of boron to PDE4 bimetal center , 2012, FEBS letters.
[34] Kate S. Carroll,et al. Redox-Sensitive Sulfenic Acid Modification Regulates Surface Expression of the Cardiovascular Voltage-Gated Potassium Channel Kv1.5 , 2012, Circulation research.
[35] J. Burrows,et al. The global pipeline of new medicines for the control and elimination of malaria , 2012, Malaria Journal.
[36] Agnieszka Adamczyk-Woźniak,et al. Biological activity of selected boronic acids and their derivatives , 2012 .
[37] Zhen Liu,et al. Recent advances in monolithic column-based boronate-affinity chromatography , 2012 .
[38] S. Martinis,et al. Structural dynamics of the aminoacylation and proof-reading functional cycle of bacterial leucyl-tRNA synthetase , 2012, Nature Structural &Molecular Biology.
[39] P. Baran,et al. Scalable, divergent synthesis of meroterpenoids via "borono-sclareolide". , 2012, Journal of the American Chemical Society.
[40] C. Furdui,et al. A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of β-ketoesters as cleavable probes. , 2012, Chemical communications.
[41] Yunchun Liu,et al. A benzoboroxole-functionalized monolithic column for the selective enrichment and separation of cis-diol containing biomolecules. , 2012, Chemical communications.
[42] M. Montenarh,et al. Control of oxidative posttranslational cysteine modifications: from intricate chemistry to widespread biological and medical applications. , 2012, Chemical research in toxicology.
[43] B. Nare,et al. Chalcone-benzoxaborole hybrid molecules as potent antitrypanosomal agents. , 2012, Journal of medicinal chemistry.
[44] Kyoung Taek Kim,et al. Monosaccharide-responsive release of insulin from polymersomes of polyboroxole block copolymers at neutral pH. , 2012, Journal of the American Chemical Society.
[45] R. Raines,et al. Boronate-Mediated Biologic Delivery , 2012, Journal of the American Chemical Society.
[46] F. Gamo,et al. Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles. , 2012, Bioorganic & medicinal chemistry letters.
[47] S. Benkovic,et al. Elucidation of the mechanism of the reaction between phenylboronic acid and a model diol, Alizarin Red S. , 2012, The Journal of organic chemistry.
[48] Stephen J Benkovic,et al. Ring Structure and Aromatic Substituent Effects on the pK a of the Benzoxaborole Pharmacophore. , 2012, ACS medicinal chemistry letters.
[49] F. Scheller,et al. Label‐free detection of enhanced saccharide binding at pH 7.4 to nanoparticulate benzoboroxole based receptor units , 2011, Journal of molecular recognition : JMR.
[50] Jason W. Locasale,et al. Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses , 2011, Science.
[51] D. Hall. Boronic acids : preparation and applications in organic synthesis, medicine and materials , 2011 .
[52] J. Balzarini,et al. Activity and safety of synthetic lectins based on benzoboroxole-functionalized polymers for inhibition of HIV entry. , 2011, Molecular pharmaceutics.
[53] J. Plattner,et al. Synthesis of novel benzoxaborole-containing phenylalanine analogues , 2011 .
[54] B. Nare,et al. Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis. , 2011, Future medicinal chemistry.
[55] Goedele Roos,et al. Protein sulfenic acid formation: from cellular damage to redox regulation. , 2011, Free radical biology & medicine.
[56] S. Benkovic,et al. Boron-containing inhibitors of synthetases. , 2011, Chemical Society reviews.
[57] Yunchun Liu,et al. A Wulff-type boronate for boronate affinity capture of cis-diol compounds at medium acidic pH condition. , 2011, Chemical communications.
[58] B. Nare,et al. SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis , 2011, PLoS neglected tropical diseases.
[59] F. Scheller,et al. Molecular imprinting of fructose using a polymerizable benzoboroxole: Effective complexation at pH 7.4 , 2011 .
[60] C. Page,et al. Phosphodiesterase inhibitors in the treatment of inflammatory diseases. , 2011, Handbook of experimental pharmacology.
[61] Yi Xia,et al. Synthesis and SAR of novel benzoxaboroles as a new class of β-lactamase inhibitors. , 2011, Bioorganic & medicinal chemistry letters.
[62] Z. Ni,et al. Synthesis and SAR of acyclic HCV NS3 protease inhibitors with novel P4-benzoxaborole moieties. , 2011, Bioorganic & medicinal chemistry letters.
[63] Yaxue Zhao,et al. Design, synthesis, and structure-activity relationship of Trypanosoma brucei leucyl-tRNA synthetase inhibitors as antitrypanosomal agents. , 2011, Journal of medicinal chemistry.
[64] Z. Ni,et al. Synthesis of new acylsulfamoyl benzoxaboroles as potent inhibitors of HCV NS3 protease. , 2010, Bioorganic & medicinal chemistry letters.
[65] Gregory M. Peterson,et al. Toenail onychomycosis: an important global disease burden , 2010, Journal of clinical pharmacy and therapeutics.
[66] R. Zhuo,et al. Enhanced gene transfection capability of polyethylenimine by incorporating boronic acid groups. , 2010, Chemical communications.
[67] Z. Ni,et al. Synthesis and evaluation of novel alpha-amino cyclic boronates as inhibitors of HCV NS3 protease. , 2010, Bioorganic & medicinal chemistry letters.
[68] K. Noguchi,et al. Kinetic and structural studies on roles of the serine ligand and a strictly conserved tyrosine residue in nitrile hydratase , 2010, JBIC Journal of Biological Inorganic Chemistry.
[69] D. Hall,et al. Design, synthesis, and screening of a library of peptidyl bis(boroxoles) as oligosaccharide receptors in water: identification of a receptor for the tumor marker TF-antigen disaccharide. , 2010, Angewandte Chemie.
[70] D. Katz,et al. Multivalent benzoboroxole functionalized polymers as gp120 glycan targeted microbicide entry inhibitors. , 2010, Molecular pharmaceutics.
[71] Agnieszka Adamczyk-Woźniak,et al. Benzoxaboroles – Old compounds with new applications , 2009 .
[72] Kate S. Carroll,et al. Profiling protein thiol oxidation in tumor cells using sulfenic acid-specific antibodies , 2009, Proceedings of the National Academy of Sciences.
[73] K. R. Maples,et al. Discovery and structure-activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis. , 2009, Bioorganic & medicinal chemistry letters.
[74] M. Yohda,et al. Catalytic Mechanism of Nitrile Hydratase Proposed by Time-resolved X-ray Crystallography Using a Novel Substrate, tert-Butylisonitrile* , 2008, Journal of Biological Chemistry.
[75] D. Hall,et al. Benzoboroxoles as efficient glycopyranoside-binding agents in physiological conditions: structure and selectivity of complex formation. , 2008, The Journal of organic chemistry.
[76] C. Winterbourn,et al. Reconciling the chemistry and biology of reactive oxygen species. , 2008, Nature chemical biology.
[77] Vincent Hernandez,et al. An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site , 2007, Science.
[78] S. Baker,et al. Recent progress on the topical therapy of onychomycosis , 2007, Expert opinion on investigational drugs.
[79] S. Baker,et al. Discovery of a new boron-containing antifungal agent, 5-fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the potential treatment of onychomycosis. , 2006, Journal of medicinal chemistry.
[80] D. Hall,et al. An improved class of sugar-binding boronic acids, soluble and capable of complexing glycosides in neutral water. , 2006, Journal of the American Chemical Society.
[81] D. Barford. The role of cysteine residues as redox-sensitive regulatory switches. , 2004, Current opinion in structural biology.
[82] Michael P. Myers,et al. Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate , 2003, Nature.
[83] Andreas Link,et al. Structural and mechanistic basis of pre- and posttransfer editing by leucyl-tRNA synthetase. , 2003, Molecular cell.
[84] L. Piddock,et al. The importance of efflux pumps in bacterial antibiotic resistance. , 2003, The Journal of antimicrobial chemotherapy.
[85] N. Shear,et al. A Risk-Benefit Assessment of the Newer Oral Antifungal Agents Used to Treat Onychomycosis , 2000, Drug safety.
[86] B. Elewski. Onychomycosis. Treatment, quality of life, and economic issues. , 2000, American journal of clinical dermatology.
[87] P. Kiprof,et al. SYNTHESIS AND STRUCTURE OF BENZOBOROXOLES: NOVEL ORGANOBORON HETEROCYCLES , 1999 .
[88] D. Patrick,et al. The impact of onychomycosis on quality of life: development of an international onychomycosis-specific questionnaire to measure patient quality of life. , 1999, Journal of the American Academy of Dermatology.
[89] Shuh Narumiya,et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension , 1997, Nature.
[90] N. Miyaura,et al. Palladium(0)-Catalyzed Cross-Coupling Reaction of Alkoxydiboron with Haloarenes: A Direct Procedure for Arylboronic Esters , 1995 .
[91] G. Wulff,et al. Selective binding to polymers via covalent bonds. The construction of chiral cavities as specific receptor sites , 1982 .
[92] H. Snyder,et al. Synthesis of Aromatic Boronic Acids. Aldehydo Boronic Acids and a Boronic Acid Analog of Tyrosine1 , 1958 .