Counterion-mediated membrane penetration: cationic cell-penetrating peptides overcome Born energy barrier by ion-pairing with phospholipids.

[1]  B. Nordén,et al.  Membrane interactions of cell-penetrating peptides probed by tryptophan fluorescence and dichroism techniques: correlations of structure to cellular uptake. , 2006, Biochemistry.

[2]  Ehud Y. Isacoff,et al.  How Far Will You Go to Sense Voltage? , 2005, Neuron.

[3]  B. Penke,et al.  Investigation of penetratin peptides. Part 2. In vitro uptake of penetratin and two of its derivatives , 2005, Journal of peptide science : an official publication of the European Peptide Society.

[4]  P. Pohl,et al.  A critical reassessment of penetratin translocation across lipid membranes. , 2005, Biophysical journal.

[5]  Simon W. Jones,et al.  Characterisation of cell‐penetrating peptide‐mediated peptide delivery , 2005, British journal of pharmacology.

[6]  M. Ferrer,et al.  Effects of cargo molecules on the cellular uptake of arginine-rich cell-penetrating peptides. , 2005, Biochimica et biophysica acta.

[7]  J. Rothbard,et al.  Adaptive translocation: the role of hydrogen bonding and membrane potential in the uptake of guanidinium-rich transporters into cells. , 2005, Advanced drug delivery reviews.

[8]  Ulo Langel,et al.  Cell-penetrating peptides: mechanism and kinetics of cargo delivery. , 2005, Advanced drug delivery reviews.

[9]  S. Futaki,et al.  Direct Observation of Anion‐Mediated Translocation of Fluorescent Oligoarginine Carriers into and across Bulk Liquid and Anionic Bilayer Membranes , 2005, Chembiochem : a European journal of chemical biology.

[10]  Y. Jan,et al.  A quantitative assessment of models for voltage-dependent gating of ion channels. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[11]  K. Swartz,et al.  Towards a structural view of gating in potassium channels , 2004, Nature Reviews Neuroscience.

[12]  B. Nordén,et al.  Vesicle membrane interactions of penetratin analogues. , 2004, Biochemistry.

[13]  J. Rothbard,et al.  Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells. , 2004, Journal of the American Chemical Society.

[14]  R. Horn,et al.  Stirring up controversy with a voltage sensor paddle , 2004, Trends in Neurosciences.

[15]  A. Woods The mighty arginine, the stable quaternary amines, the powerful aromatics, and the aggressive phosphate: their role in the noncovalent minuet. , 2004, Journal of proteome research.

[16]  L. Roudaia,et al.  Penetratin and related cell-penetrating cationic peptides can translocate across lipid bilayers in the presence of a transbilayer potential. , 2003, Biochemistry.

[17]  S. Matile,et al.  Anion-mediated transfer of polyarginine across liquid and bilayer membranes. , 2003, Journal of the American Chemical Society.

[18]  B. Nordén,et al.  Uptake of analogs of penetratin, Tat(48-60) and oligoarginine in live cells. , 2003, Biochemical and biophysical research communications.

[19]  L. Mäler,et al.  Structure and positioning comparison of two variants of penetratin in two different membrane mimicking systems by NMR. , 2003, European journal of biochemistry.

[20]  M. Cadene,et al.  X-ray structure of a voltage-dependent K+ channel , 2003, Nature.

[21]  Youxing Jiang,et al.  The principle of gating charge movement in a voltage-dependent K+ channel , 2003, Nature.

[22]  B. Nordén,et al.  Application of a novel analysis to measure the binding of the membrane-translocating peptide penetratin to negatively charged liposomes. , 2003, Biochemistry.

[23]  B. L. Wylie,et al.  Arginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular uptake. , 2002, Journal of medicinal chemistry.

[24]  B. Nordén,et al.  Penetratin‐induced aggregation and subsequent dissociation of negatively charged phospholipid vesicles , 2001, FEBS letters.

[25]  Ű. Langel,et al.  Interaction and structure induction of cell-penetrating peptides in the presence of phospholipid vesicles. , 2001, Biochimica et biophysica acta.

[26]  B. Nordén,et al.  The Antennapedia peptide penetratin translocates across lipid bilayers – the first direct observation , 2000, FEBS letters.

[27]  Q. Al-Awqati One hundred years of membrane permeability: does Overton still rule? , 1999, Nature Cell Biology.

[28]  Stephen H. White,et al.  Experimentally determined hydrophobicity scale for proteins at membrane interfaces , 1996, Nature Structural Biology.

[29]  A. Prochiantz,et al.  Cell Internalization of the Third Helix of the Antennapedia Homeodomain Is Receptor-independent* , 1996, The Journal of Biological Chemistry.

[30]  T. Creamer,et al.  Solvation energies of amino acid side chains and backbone in a family of host-guest pentapeptides. , 1996, Biochemistry.

[31]  S H White,et al.  Direct measurement of salt-bridge solvation energies using a peptide model system: implications for protein stability. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[32]  W. Cramer,et al.  On the physical basis for the cis‐positive rule describing protein orientation in biological membranes , 1995, FEBS letters.

[33]  A. Prochiantz,et al.  The third helix of the Antennapedia homeodomain translocates through biological membranes. , 1994, The Journal of biological chemistry.

[34]  D. Engelman,et al.  Lipid bilayer thickness varies linearly with acyl chain length in fluid phosphatidylcholine vesicles. , 1983, Journal of molecular biology.

[35]  A. Parsegian,et al.  Energy of an Ion crossing a Low Dielectric Membrane: Solutions to Four Relevant Electrostatic Problems , 1969, Nature.

[36]  M. Born Volumen und Hydratationswärme der Ionen , 1920 .

[37]  M. Giacca,et al.  Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat. , 2002, European journal of biochemistry.

[38]  R. New,et al.  Liposomes : a practical approach , 1990 .

[39]  R. Bell,et al.  The electrostatic energy of dipole molecules in different media , 1931 .