Flow infusion electrospray ionisation mass spectrometry for high throughput, non-targeted metabolite fingerprinting: a review

[1]  Yinghong Wang,et al.  [Quantitative metabolomics based on NMR]. , 2014, Yao xue xue bao = Acta pharmaceutica Sinica.

[2]  Boniek G. Vaz,et al.  Varietal discrimination of Chilean wines by direct injection mass spectrometry analysis combined with multivariate statistics , 2012 .

[3]  P. Albertson,et al.  Aging effects on macadamia nut oil studied by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. , 2012, Journal of agricultural and food chemistry.

[4]  S. Neumann,et al.  CAMERA: an integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets. , 2012, Analytical chemistry.

[5]  J. Mathers,et al.  Use of mass spectrometry fingerprinting to identify urinary metabolites after consumption of specific foods. , 2011, The American journal of clinical nutrition.

[6]  Bin Hu,et al.  Electrospray ionization using wooden tips. , 2011, Analytical chemistry.

[7]  R. Cooks,et al.  Leaf spray: direct chemical analysis of plant material and living plants by mass spectrometry. , 2011, Analytical chemistry.

[8]  J. Mathers,et al.  Proline betaine and its biotransformation products in fasting urine samples are potential biomarkers of habitual citrus fruit consumption. , 2011, The British journal of nutrition.

[9]  Egon L. Willighagen,et al.  Elemental composition determination based on MSn , 2011, Bioinform..

[10]  M. Eberlin,et al.  Monitoring of wine aging process by electrospray ionization mass spectrometry , 2011 .

[11]  Royston Goodacre,et al.  Metabolomic approaches reveal that cell wall modifications play a major role in ethylene-mediated resistance against Botrytis cinerea. , 2011, The Plant journal : for cell and molecular biology.

[12]  E. Ragazzi,et al.  A metabolite fingerprinting for the characterization of commercial botanical dietary supplements , 2011, Metabolomics.

[13]  Nicola Zamboni,et al.  High-throughput, accurate mass metabolome profiling of cellular extracts by flow injection-time-of-flight mass spectrometry. , 2011, Analytical chemistry.

[14]  Elizabeth B. Kujawinski,et al.  Characterization of dissolved organic matter in Lake Superior and its watershed using ultrahigh resolution mass spectrometry , 2011 .

[15]  D. Wishart Advances in metabolite identification. , 2011, Bioanalysis.

[16]  Fabian J Theis,et al.  Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers , 2011, PLoS genetics.

[17]  Pei Chen,et al.  A flow-injection mass spectrometry fingerprinting method for authentication and quality assessment of Scutellaria lateriflora-based dietary supplements , 2011, Analytical and bioanalytical chemistry.

[18]  B. Finlay,et al.  Metabolomics Reveals Phospholipids as Important Nutrient Sources during Salmonella Growth in Bile In Vitro and In Vivo , 2011, Journal of bacteriology.

[19]  A. Smilde,et al.  Double-check: validation of diagnostic statistics for PLS-DA models in metabolomics studies , 2011, Metabolomics.

[20]  Joshua D. Knowles,et al.  Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry , 2011, Nature Protocols.

[21]  Hannelore Daniel,et al.  Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention. , 2011, Physiological genomics.

[22]  W. Hou,et al.  Identification of coumarins in traditional Chinese medicine by direct-injection electrospray ionisation tandem mass spectrometry and high-performance liquid chromatography-mass spectrometry , 2011 .

[23]  J. Mathers,et al.  Development and validation of a standardized protocol to monitor human dietary exposure by metabolite fingerprinting of urine samples , 2011, Metabolomics.

[24]  Douglas B. Kell,et al.  Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets , 2011, Bioinform..

[25]  B. Finlay,et al.  Impact of Salmonella Infection on Host Hormone Metabolism Revealed by Metabolomics , 2011, Infection and Immunity.

[26]  R. Cooks,et al.  Direct analysis of biological tissue by paper spray mass spectrometry. , 2011, Analytical chemistry.

[27]  R. Helm,et al.  Mass spectral analyses of corn stover prehydrolysates to assess conditioning processes. , 2010, Journal of agricultural and food chemistry.

[28]  T. Hankemeier,et al.  Quantitative metabolomics based on gas chromatography mass spectrometry: status and perspectives , 2010, Metabolomics.

[29]  Mark R. Viant,et al.  MI-Pack: Increased confidence of metabolite identification in mass spectra by integrating accurate masses and metabolic pathways , 2010 .

[30]  J. W. Allwood,et al.  A combined ¹H nuclear magnetic resonance and electrospray ionization-mass spectrometry analysis to understand the basal metabolism of plant-pathogenic Fusarium spp. , 2010, Molecular plant-microbe interactions : MPMI.

[31]  Mark E Arnold,et al.  Identifying, evaluating, and controlling bioanalytical risks resulting from nonuniform matrix ion suppression/enhancement and nonlinear liquid chromatography-mass spectrometry assay response. , 2010, Analytical chemistry.

[32]  R. Sleighter,et al.  Ultrahigh resolution mass spectrometry and indicator species analysis to identify marker components of soil- and plant biomass- derived organic matter fractions. , 2010, Environmental science & technology.

[33]  Xiaomei Yan,et al.  Direct infusion mass spectrometry or liquid chromatography mass spectrometry for human metabonomics? A serum metabonomic study of kidney cancer. , 2010, The Analyst.

[34]  E. Schleicher,et al.  Insulin Sensitivity Is Reflected by Characteristic Metabolic Fingerprints - A Fourier Transform Mass Spectrometric Non-Targeted Metabolomics Approach , 2010, PloS one.

[35]  Oliver Fiehn,et al.  Advances in structure elucidation of small molecules using mass spectrometry , 2010, Bioanalytical reviews.

[36]  G Madalinski,et al.  Fourier transform mass spectrometry for metabolome analysis. , 2010, The Analyst.

[37]  S. Giovannoni,et al.  Impact of instrument and experiment parameters on reproducibility of ultrahigh resolution ESI FT-ICR mass spectra of natural organic matter. , 2010 .

[38]  Bin Hu,et al.  Principle and Application of Ambient Mass Spectrometry for Direct Analysis of Complex Samples , 2010 .

[39]  Sonia J. Miller,et al.  The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato. , 2010, The Plant journal : for cell and molecular biology.

[40]  R. Augusti,et al.  Extra virgin (EV) and ordinary (ON) olive oils: distinction and detection of adulteration (EV with ON) as determined by direct infusion electrospray ionization mass spectrometry and chemometric approaches. , 2010, Rapid communications in mass spectrometry : RCM.

[41]  Pei Chen,et al.  Mass spectroscopic fingerprinting method for differentiation between Scutellaria lateriflora and the germander (Teucrium canadense and T. chamaedrys) species. , 2010, Journal of AOAC International.

[42]  Maria Liakata,et al.  Enhancement of Plant Metabolite Fingerprinting by Machine Learning1[W] , 2010, Plant Physiology.

[43]  Katsutoshi Takahashi,et al.  A strategy for the determination of the elemental composition by fourier transform ion cyclotron resonance mass spectrometry based on isotopic peak ratios. , 2010, Analytical chemistry.

[44]  J. Yamate,et al.  Metabolic Fingerprinting in Toxicological Assessment Using FT-ICR MS , 2010, Journal of toxicologic pathology.

[45]  Shuiping Yang,et al.  Rapid analysis of aerosol drugs using nano extractive electrospray ionization tandem mass spectrometry. , 2010, The Analyst.

[46]  Kazuki Saito,et al.  Metabolomics for functional genomics, systems biology, and biotechnology. , 2010, Annual review of plant biology.

[47]  Gene E. Lester,et al.  Flow injection mass spectral fingerprints demonstrate chemical differences in Rio Red grapefruit with respect to year, harvest time, and conventional versus organic farming. , 2010, Journal of agricultural and food chemistry.

[48]  Huanwen Chen,et al.  Sampling analytes from cheese products for fast detection using neutral desorption extractive electrospray ionization mass spectrometry , 2010, Analytical and bioanalytical chemistry.

[49]  M. Viant,et al.  Application of metabolomics to investigate the process of human orthotopic liver transplantation: a proof-of-principle study. , 2010, Omics : a journal of integrative biology.

[50]  Shigehiko Kanaya,et al.  Application of Fourier-transform ion cyclotron resonance mass spectrometry to metabolic profiling and metabolite identification. , 2010, Current opinion in biotechnology.

[51]  Paul G. Jones,et al.  Metabolite fingerprinting of urine suggests breed-specific dietary metabolism differences in domestic dogs , 2009, British Journal of Nutrition.

[52]  David S Wishart,et al.  Computational strategies for metabolite identification in metabolomics. , 2009, Bioanalysis.

[53]  P. Schmitt‐Kopplin,et al.  Unraveling different chemical fingerprints between a champagne wine and its aerosols , 2009, Proceedings of the National Academy of Sciences.

[54]  N. Talbot,et al.  Metabolomic analysis reveals a common pattern of metabolic re-programming during invasion of three host plant species by Magnaporthe grisea. , 2009, The Plant journal : for cell and molecular biology.

[55]  Bin Hu,et al.  Extractive electrospray ionization mass spectrometry toward in situ analysis without sample pretreatment. , 2009, Analytical chemistry.

[56]  J. Jansson,et al.  Metabolomics Reveals Metabolic Biomarkers of Crohn's Disease , 2009, PloS one.

[57]  Wanchang Lin,et al.  Metabolite signal identification in accurate mass metabolomics data with MZedDB, an interactive m/z annotation tool utilising predicted ionisation behaviour 'rules' , 2009, BMC Bioinformatics.

[58]  L. Willmitzer,et al.  13C isotope-labeled metabolomes allowing for improved compound annotation and relative quantification in liquid chromatography-mass spectrometry-based metabolomic research. , 2009, Analytical chemistry.

[59]  D. Kell,et al.  Mass Spectrometry Tools and Metabolite-specific Databases for Molecular Identification in Metabolomics , 2009 .

[60]  Oliver Fiehn,et al.  Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research , 2009, Metabolomics.

[61]  Philippe Schmitt-Kopplin,et al.  The chemodiversity of wines can reveal a metabologeography expression of cooperage oak wood , 2009, Proceedings of the National Academy of Sciences.

[62]  Theodoros N. Arvanitis,et al.  A signal filtering method for improved quantification and noise discrimination in fourier transform ion cyclotron resonance mass spectrometry-based metabolomics data , 2009, Journal of the American Society for Mass Spectrometry.

[63]  Albert Koulman,et al.  RAPID COMMUNICATIONS IN MASS SPECTROMETRY Rapid Commun. Mass Spectrom. 2009; 23: 1411–1418 , 2022 .

[64]  Nozomu Sakurai,et al.  Metabolomics for the characterization of cytochromes P450-dependent fatty acid hydroxylation reactions in Arabidopsis , 2009 .

[65]  Theodoros N. Arvanitis,et al.  A new approach to toxicity testing in Daphnia magna: application of high throughput FT-ICR mass spectrometry metabolomics , 2009, Metabolomics.

[66]  Lothar Willmitzer,et al.  High-resolution direct infusion-based mass spectrometry in combination with whole 13C metabolome isotope labeling allows unambiguous assignment of chemical sum formulas. , 2008, Analytical chemistry.

[67]  I. Rusyn,et al.  Metabolomic profiling of a modified alcohol liquid diet model for liver injury in the mouse uncovers new markers of disease. , 2008, Toxicology and applied pharmacology.

[68]  Devanand L. Luthria,et al.  Discriminating between cultivars and treatments of broccoli using mass spectral fingerprinting and analysis of variance-principal component analysis. , 2008, Journal of agricultural and food chemistry.

[69]  J. Nielsen,et al.  The yeast metabolome addressed by electrospray ionization mass spectrometry: Initiation of a mass spectral library and its applications for metabolic footprinting by direct infusion mass spectrometry , 2008, Metabolomics.

[70]  M. Giné Flow Injection Mass Spectrometry , 2008 .

[71]  Sangkyu Park,et al.  Induced metabolite changes inMyriophyllum spicatum during co-existence experiment with the cyanobacteriumMicrocystis aeruginosa , 2008, Journal of Plant Biology.

[72]  Xiangdong Li,et al.  Molecular formula and METLIN Personal Metabolite Database matching applied to the identification of compounds generated by LC/TOF-MS. , 2008, Journal of biomolecular techniques : JBT.

[73]  D. Stewart,et al.  Towards fruitful metabolomics: high throughput analyses of polyphenol composition in berries using direct infusion mass spectrometry. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[74]  Christophe Junot,et al.  Mass spectrometry for the identification of the discriminating signals from metabolomics: current status and future trends. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[75]  D. Kell,et al.  Metabolic profiling of serum using Ultra Performance Liquid Chromatography and the LTQ-Orbitrap mass spectrometry system. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[76]  Xianlin Han,et al.  Microfluidics-based electrospray ionization enhances the intrasource separation of lipid classes and extends identification of individual molecular species through multi-dimensional mass spectrometry: development of an automated high-throughput platform for shotgun lipidomics. , 2008, Rapid communications in mass spectrometry : RCM.

[77]  Nozomu Sakurai,et al.  A tool for high-throughput prediction of molecular formulas and identification of isotopic peaks from large-scale mass spectrometry data , 2008 .

[78]  Hideyuki Suzuki,et al.  Characterization of orphan monooxygenases by rapid substrate screening using FT-ICR mass spectrometry. , 2008, Chemistry & biology.

[79]  G. González‐Gaitano,et al.  Multivariate statistical analysis of mass spectra as a tool for the classification of the main humic substances according to their structural and conformational features. , 2008, Journal of agricultural and food chemistry.

[80]  R. Sleighter,et al.  Molecular characterization of dissolved organic matter (DOM) along a river to ocean transect of the lower Chesapeake Bay by ultrahigh resolution electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry , 2008 .

[81]  Shigehiko Kanaya,et al.  Metabolomics approach for determining growth-specific metabolites based on Fourier transform ion cyclotron resonance mass spectrometry , 2008, Analytical and bioanalytical chemistry.

[82]  A. Marshall,et al.  High-resolution mass spectrometers. , 2008, Annual review of analytical chemistry.

[83]  S. Kanaya,et al.  Metabolite annotations based on the integration of mass spectral information , 2008, The Plant journal : for cell and molecular biology.

[84]  C. Junot,et al.  Direct introduction of biological samples into a LTQ-Orbitrap hybrid mass spectrometer as a tool for fast metabolome analysis. , 2008, Analytical chemistry.

[85]  Emilie Duval,et al.  High-throughput, nontargeted metabolite fingerprinting using nominal mass flow injection electrospray mass spectrometry , 2008, Nature Protocols.

[86]  John Draper,et al.  Rice blast infection of Brachypodium distachyon as a model system to study dynamic host/pathogen interactions , 2008, Nature Protocols.

[87]  John Draper,et al.  Explanatory signal interpretation and metabolite identification strategies for nominal mass FIE-MS metabolite fingerprints , 2008, Nature Protocols.

[88]  Wanchang Lin,et al.  Preprocessing, classification modeling and feature selection using flow injection electrospray mass spectrometry metabolite fingerprint data , 2008, Nature Protocols.

[89]  Warwick B Dunn,et al.  Current trends and future requirements for the mass spectrometric investigation of microbial, mammalian and plant metabolomes , 2008, Physical biology.

[90]  I. Rusyn,et al.  Towards high-throughput metabolomics using ultrahigh-field Fourier transform ion cyclotron resonance mass spectrometry , 2008, Metabolomics.

[91]  J. Antón,et al.  Metabolic evidence for biogeographic isolation of the extremophilic bacterium Salinibacter ruber , 2008, The ISME Journal.

[92]  Age K. Smilde,et al.  UvA-DARE ( Digital Academic Repository ) Assessment of PLSDA cross validation , 2008 .

[93]  F. Woodward,et al.  Population-specific metabolic phenotypes of Arabidopsis lyrata ssp. petraea. , 2007, The New phytologist.

[94]  M. Eberlin,et al.  Biodiesel Typification and Quality Control by Direct Infusion Electrospray Ionization Mass Spectrometry Fingerprinting , 2007 .

[95]  J. Yamate,et al.  Urinary metabolic fingerprinting for amiodarone-induced phospholipidosis in rats using FT-ICR MS. , 2007, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

[96]  S. Kanaya,et al.  Metabolic profiling using Fourier-transform ion-cyclotron-resonance mass spectrometry , 2007, Analytical and bioanalytical chemistry.

[97]  Huanwen Chen,et al.  Neutral desorption sampling coupled to extractive electrospray ionization mass spectrometry for rapid differentiation of biosamples by metabolomic fingerprinting. , 2007, Journal of mass spectrometry : JMS.

[98]  Serge Rudaz,et al.  Development of a two-step screening ESI-TOF-MS method for rapid determination of significant stress-induced metabolome modifications in plant leaf extracts: the wound response in Arabidopsis thaliana as a case study. , 2007, Journal of separation science.

[99]  Douglas B. Kell,et al.  Proposed minimum reporting standards for data analysis in metabolomics , 2007, Metabolomics.

[100]  John Draper,et al.  Statistical measures for validating plant genotype similarity assessments following multivariate analysis of metabolome fingerprint data , 2007, Metabolomics.

[101]  Akira Oikawa,et al.  Differential metabolomics unraveling light/dark regulation of metabolic activities in Arabidopsis cell culture , 2007, Planta.

[102]  Royston Goodacre,et al.  Metabolic footprinting as a tool for discriminating between brewing yeasts , 2007, Yeast.

[103]  M. Beckmann,et al.  Detecting a difference – assessing generalisability when modelling metabolome fingerprint data in longer term studies of genetically modified plants , 2007, Metabolomics.

[104]  D. R. Causton,et al.  The application of MANOVA to analyse Arabidopsis thaliana metabolomic data from factorially designed experiments , 2007, Metabolomics.

[105]  Theodoros N. Arvanitis,et al.  Dynamic range and mass accuracy of wide-scan direct infusion nanoelectrospray fourier transform ion cyclotron resonance mass spectrometry-based metabolomics increased by the spectral stitching method. , 2007, Analytical chemistry.

[106]  W. Cooper,et al.  Molecular characterization of dissolved organic matter in a North Brazilian mangrove porewater and mangrove-fringed estuaries by ultrahigh resolution Fourier Transform-Ion Cyclotron Resonance mass spectrometry and excitation/emission spectroscopy , 2007 .

[107]  John Draper,et al.  Representation, comparison, and interpretation of metabolome fingerprint data for total composition analysis and quality trait investigation in potato cultivars. , 2007, Journal of agricultural and food chemistry.

[108]  Michael Edberg Hansen,et al.  A comparison of direct infusion MS and GC-MS for metabolic footprinting of yeast mutants. , 2007, Biotechnology and bioengineering.

[109]  J. Keurentjes,et al.  Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometry , 2007, Nature Protocols.

[110]  Oliver Fiehn,et al.  Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry , 2007, BMC Bioinformatics.

[111]  Christoph W. Sensen,et al.  Gene transcript and metabolite profiling of elicitor-induced opium poppy cell cultures reveals the coordinate regulation of primary and secondary metabolism , 2007, Planta.

[112]  Steffen Neumann,et al.  Annotation of LC/ESI-MS Mass Signals , 2007, BIRD.

[113]  K. Fraser,et al.  High-throughput direct-infusion ion trap mass spectrometry: a new method for metabolomics. , 2007, Rapid communications in mass spectrometry : RCM.

[114]  Douglas B. Kell,et al.  Statistical strategies for avoiding false discoveries in metabolomics and related experiments , 2007, Metabolomics.

[115]  T. Dittmar,et al.  Thermogenic organic matter dissolved in the abyssal ocean , 2006 .

[116]  Norbert Stoll,et al.  Isotope pattern evaluation for the reduction of elemental compositions assigned to high-resolution mass spectral data from electrospray ionization fourier transform ion cyclotron resonance mass spectrometry , 2006, Journal of the American Society for Mass Spectrometry.

[117]  T. Gillespie,et al.  A review of nanoelectrospray ionization applications for drug metabolism and pharmacokinetics. , 2006, Current drug metabolism.

[118]  John Draper,et al.  Predicting interpretability of metabolome models based on behavior, putative identity, and biological relevance of explanatory signals , 2006, Proceedings of the National Academy of Sciences.

[119]  S. Kanaya,et al.  Clarification of Pathway-Specific Inhibition by Fourier Transform Ion Cyclotron Resonance/Mass Spectrometry-Based Metabolic Phenotyping Studies1[W] , 2006, Plant Physiology.

[120]  R. A. van den Berg,et al.  Centering, scaling, and transformations: improving the biological information content of metabolomics data , 2006, BMC Genomics.

[121]  A. Fernie,et al.  Gas chromatography mass spectrometry–based metabolite profiling in plants , 2006, Nature Protocols.

[122]  David I. Ellis,et al.  Metabolomic approaches reveal that phosphatidic and phosphatidyl glycerol phospholipids are major discriminatory non-polar metabolites in responses by Brachypodium distachyon to challenge by Magnaporthe grisea. , 2006, The Plant journal : for cell and molecular biology.

[123]  Oliver Fiehn,et al.  Metabolomic database annotations via query of elemental compositions: Mass accuracy is insufficient even at less than 1 ppm , 2006, BMC Bioinformatics.

[124]  Sunghwan Kim,et al.  Biodegradable dissolved organic matter in a temperate and a tropical stream determined from ultra‐high resolution mass spectrometry , 2006 .

[125]  S. Gatzek,et al.  Controlled protein precipitation in combination with chip-based nanospray infusion mass spectrometry. An approach for metabolomics profiling of plasma. , 2005, Analytical chemistry.

[126]  Nigel W. Hardy,et al.  Hierarchical metabolomics demonstrates substantial compositional similarity between genetically modified and conventional potato crops. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[127]  J. Nielsen,et al.  Mass spectrometry in metabolome analysis. , 2005, Mass spectrometry reviews.

[128]  Gerhard Kattner,et al.  Molecular formulae of marine and terrigenous dissolved organic matter detected by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry , 2005 .

[129]  D. Lightfoot,et al.  Metabolite Fingerprinting in Transgenic Nicotiana tabacum Altered by the Escherichia coli Glutamate Dehydrogenase Gene , 2005, Journal of biomedicine & biotechnology.

[130]  Doug Heath,et al.  A global reorganization of the metabolome in Arabidopsis during cold acclimation is revealed by metabolic fingerprinting , 2005 .

[131]  W. Dunn,et al.  Measuring the metabolome: current analytical technologies. , 2005, The Analyst.

[132]  W. Dunn,et al.  Evaluation of automated electrospray-TOF mass spectrometryfor metabolic fingerprinting of the plant metabolome , 2005, Metabolomics.

[133]  M. Hirai,et al.  Functional genomics by integrated analysis of metabolome and transcriptome of Arabidopsis plants over-expressing an MYB transcription factor. , 2005, The Plant journal : for cell and molecular biology.

[134]  G. Kruppa,et al.  Metabolomics applications of FT-ICR mass spectrometry. , 2005, Mass spectrometry reviews.

[135]  M. Gross,et al.  Accurate mass measurements by Fourier transform mass spectrometry , 2005 .

[136]  J. Rossier,et al.  Thin chip microsprayer system coupled to quadrupole time-of-flight mass spectrometer for glycoconjugate analysis. , 2005, Lab on a chip.

[137]  Christophe Junot,et al.  Liquid chromatography-mass spectrometry and 15N metabolic labeling for quantitative metabolic profiling. , 2005, Analytical chemistry.

[138]  J. Antignac,et al.  The ion suppression phenomenon in liquid chromatography–mass spectrometry and its consequences in the field of residue analysis , 2005 .

[139]  Milos Hauskrecht,et al.  ORIGINAL RESEARCH Assessing the Statistical Significance of the Achieved Classification Error of Classifiers Constructed using Serum Peptide Profiles, and a Prescription for Random Sampling Repeated Studies for Massive , 2022 .

[140]  L. Sweetlove,et al.  Application of metabolite profiling to the identification of traits in a population of tomato introgression lines. , 2004, Journal of experimental botany.

[141]  G. C. Klein,et al.  Probing molecular-level transformations of dissolved organic matter: insights on photochemical degradation and protozoan modification of DOM from electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry , 2004 .

[142]  Joachim Selbig,et al.  Metabolite fingerprinting: detecting biological features by independent component analysis , 2004, Bioinform..

[143]  Douglas B. Kell,et al.  Discrimination of Modes of Action of Antifungal Substances by Use of Metabolic Footprinting , 2004, Applied and Environmental Microbiology.

[144]  Kazuki Saito,et al.  Potential of metabolomics as a functional genomics tool. , 2004, Trends in plant science.

[145]  M. Hirai,et al.  Integration of transcriptomics and metabolomics for understanding of global responses to nutritional stresses in Arabidopsis thaliana. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[146]  E. Cappelletti,et al.  Detection of hypericins in the "red glands" of Hypericum elodes by ESI-MS/MS. , 2004, Phytochemistry.

[147]  Richard Baumgartner,et al.  Class prediction and discovery using gene microarray and proteomics mass spectroscopy data: curses, caveats, cautions , 2003, Bioinform..

[148]  T. Annesley Ion suppression in mass spectrometry. , 2003, Clinical chemistry.

[149]  Douglas B. Kell,et al.  Functional Genomics Via Metabolic Footprinting: Monitoring Metabolite Secretion by Escherichia Coli Tryptophan Metabolism Mutants Using FT–IR and Direct Injection Electrospray Mass Spectrometry , 2003, Comparative and functional genomics.

[150]  G. Willett,et al.  High-Resolution Electrospray-Ionization Fourier-Transform Ion Cyclotron Resonance and Gas Chromatography–Mass Spectrometry of Macadamia Nut Oil , 2003 .

[151]  D. Kell,et al.  High-throughput classification of yeast mutants for functional genomics using metabolic footprinting , 2003, Nature Biotechnology.

[152]  Andrew Hayes,et al.  An optimized protocol for metabolome analysis in yeast using direct infusion electrospray mass spectrometry. , 2003, Phytochemistry.

[153]  R. Goodacre,et al.  Chemometric discrimination of unfractionated plant extracts analyzed by electrospray mass spectrometry. , 2003, Phytochemistry.

[154]  R. Dixon,et al.  Plant metabolomics: large-scale phytochemistry in the functional genomics era. , 2003, Phytochemistry.

[155]  A. Marshall,et al.  Exact masses and chemical formulas of individual Suwannee River fulvic acids from ultrahigh resolution electrospray ionization Fourier transform ion cyclotron resonance mass spectra. , 2003, Analytical chemistry.

[156]  Spencer J. Williams,et al.  Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[157]  C. Gardana,et al.  Analytical methods for quality control of propolis. , 2002, Fitoterapia.

[158]  D. Kell,et al.  Metabolic profiling using direct infusion electrospray ionisation mass spectrometry for the characterisation of olive oils. , 2002, The Analyst.

[159]  D. Kell,et al.  Flow-injection electrospray ionization mass spectrometry of crude cell extracts for high-throughput bacterial identification , 2002, Journal of the American Society for Mass Spectrometry.

[160]  H. Cooper,et al.  Electrospray ionization Fourier transform mass spectrometric analysis of wine. , 2001, Journal of agricultural and food chemistry.

[161]  Leo Breiman,et al.  Random Forests , 2001, Machine Learning.

[162]  D B Kell,et al.  Discrimination of aerobic endospore-forming bacteria via electrospray-lonization mass spectrometry of whole cell suspensions. , 2001, Analytical chemistry.

[163]  D. Favretto,et al.  Monitoring the production yields of vincristine and vinblastine in Catharanthus roseus from somatic embryogenesis. Semiquantitative determination by flow-injection electrospray ionization mass spectrometry. , 2001, Rapid communications in mass spectrometry : RCM.

[164]  R. Higgs,et al.  Use of Direct-Infusion Electrospray Mass Spectrometry To Guide Empirical Development of Improved Conditions for Expression of Secondary Metabolites from Actinomycetes , 2001, Applied and Environmental Microbiology.

[165]  Richard E. Higgs,et al.  Rapid Method To Estimate the Presence of Secondary Metabolites in Microbial Extracts , 2001, Applied and Environmental Microbiology.

[166]  Timothy Olah,et al.  Mechanistic investigation of ionization suppression in electrospray ionization , 2000, Journal of the American Society for Mass Spectrometry.

[167]  Corso,et al.  A fully integrated monolithic microchip electrospray device for mass spectrometry , 2000, Analytical chemistry.

[168]  P. Mauri,et al.  Electrospray characterization of selected medicinal plant extracts. , 2000, Journal of pharmaceutical and biomedical analysis.

[169]  P. Mauri,et al.  High performance liquid chromatography/electrospray mass spectrometry of Hypericum perforatum extracts. , 2000, Rapid communications in mass spectrometry : RCM.

[170]  P. Mauri,et al.  Liquid chromatography/electrospray mass spectrometry of bioactive terpenoids in Ginkgo biloba L. , 1999, Journal of mass spectrometry : JMS.

[171]  Ekkehard Görlach and,et al.  Discovery of Quasi-Molecular Ions in Electrospray Spectra by Automated Searching for Simultaneous Adduct Mass Differences , 1999 .

[172]  Douglas B. Kell,et al.  Characterisation of intact microorganisms using electrospray ionisation mass spectrometry , 1999 .

[173]  D. Favretto,et al.  Characterization of the anthocyanins of Catharanthus roseus (L.) G. Don in vivo and in vitro by electrospray ionization ion trap mass spectrometry , 1998 .

[174]  M. Guilhaus,et al.  PERFECT TIMING : TIME-OF-FLIGHT MASS SPECTROMETRY , 1997 .

[175]  R. March An Introduction to Quadrupole Ion Trap Mass Spectrometry , 1997 .

[176]  W. Windig,et al.  A Noise and Background Reduction Method for Component Detection in Liquid Chromatography/Mass Spectrometry , 1996 .

[177]  J. Frisvad,et al.  Using direct electrospray mass spectrometry in taxonomy and secondary metabolite profiling of crude fungal extracts , 1996 .

[178]  Yasushi Yamamura,et al.  Application of Electronics , 1991 .

[179]  Petr G. Lokhov,et al.  Diagnosis of lung cancer based on direct-infusion electrospray mass spectrometry of blood plasma metabolites , 2012 .

[180]  Chen Huan Fundamental Principles and Practical Applications of Ambient Ionization Mass Spectrometry for Direct Analysis of Complex Samples , 2010 .

[181]  Li Yang,et al.  Screening phosphatidylcholine biomarkers in mouse liver extracts from a hypercholesterolemia study using ESI-MS and chemometrics , 2009, Analytical and bioanalytical chemistry.

[182]  Costas S. Iliopoulos,et al.  Bioinformatics Research and Development, Proceedings , 2008 .

[183]  M. Zenk,et al.  Poppy alkaloid profiling by electrospray tandem mass spectrometry and electrospray FT-ICR mass spectrometry after [ring-13C6]-tyramine feeding. , 2007, Phytochemistry.

[184]  B. Hammock,et al.  Mass spectrometry-based metabolomics. , 2007, Mass spectrometry reviews.

[185]  P. J. Todd,et al.  Mass Spectrometry: A Textbook , 2007 .

[186]  O. Fiehn Metabolomics – the link between genotypes and phenotypes , 2004, Plant Molecular Biology.

[187]  D. Goodenowe,et al.  Nontargeted metabolome analysis by use of Fourier Transform Ion Cyclotron Mass Spectrometry. , 2002, Omics : a journal of integrative biology.

[188]  Nigel W. Hardy,et al.  Plant Metabolomics , 2002, The Plant Cell Online.

[189]  D. Favretto,et al.  Application of Electrospray Ionization Mass Spectrometry to the Study of Grape Anthocyanins , 2000, American Journal of Enology and Viticulture.

[190]  J. Frisvad,et al.  Terverticillate penicillia studied by direct electrospray mass spectrometric profiling of crude extracts. I. Chemosystematics , 1997 .