Development and utilization of an intelligent application for aiding COVID-19 diagnosis

On basis of laboratory examinations indicators from a total of 620 samples, a machine learning-based diagnosis model was developed, and subsequently implemented as a COVID-19 diagnosis aid APP. External validation showed satisfiable model prediction performance (i.e., AUC= 0.872) which guarantees the promising use of this tool for extensive screening.

[1]  Q. Tao,et al.  Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases , 2020, Radiology.

[2]  Michael R. Thomas,et al.  Taking connected mobile-health diagnostics of infectious diseases to the field , 2019, Nature.

[3]  Hiroshi Nishiura,et al.  Communicating the Risk of Death from Novel Coronavirus Disease (COVID-19) , 2020, Journal of clinical medicine.

[4]  Randi E. Foraker,et al.  VALIDATION OF THE ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD) POOLED COHORT RISK EQUATIONS BY EDUCATION LEVEL: THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY , 2016 .

[5]  E. Elkin,et al.  Decision Curve Analysis: A Novel Method for Evaluating Prediction Models , 2006, Medical decision making : an international journal of the Society for Medical Decision Making.

[6]  F. Shan,et al.  Emerging 2019 Novel Coronavirus (2019-nCoV) Pneumonia , 2020, Radiology.

[7]  R. Tibshirani.  The lasso method for variable selection in the Cox model. , 1997, Statistics in medicine.

[8]  Eric V Granowitz,et al.  Using the Internet to identify infectious-disease outbreaks. , 2004, The New England journal of medicine.

[9]  Bin Liu,et al.  Dynamics of breast cancer relapse reveal late recurring ER-positive genomic subgroups , 2019, Nature.

[10]  G. Leung,et al.  Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study , 2020, The Lancet.

[11]  Mary Cushman,et al.  Validation of the atherosclerotic cardiovascular disease Pooled Cohort risk equations. , 2014, JAMA.

[12]  C. Campèse,et al.  First cases of coronavirus disease 2019 (COVID-19) in France: surveillance, investigations and control measures, January 2020 , 2020, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

[13]  Zunyou Wu,et al.  Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. , 2020, JAMA.