Automatic sleep apnoea detection using measures of amplitude and heart rate variability from the electrocardiogram

A method for the automatic processing of the electrocardiogram (ECG) for the detection of disordered breathing associated with obstructive sleep apnoea is presented. The method provides a minute-by-minute analysis of night-time single lead ECG recordings. An independently validated database of 35 ECG recordings acquired from normal subjects and subjects with obstructive and mixed sleep apnoea, each of approximately eight hours in duration, was used throughout the study. A wide variety of features based on heart beat intervals and an electrocardiogram derived respiratory signal were considered. Classifiers based on linear and quadratic discriminants were used. Results show that a 90% success rate in correctly identifying one-minute segments containing disordered breathing is achievable.

[1]  Daniel J Buysse,et al.  Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. , 1999, Sleep.

[2]  G. Santarelli Screening of obstructive sleep apnea syndrome by heart rate variability analysis , 2000 .

[3]  G. Moody,et al.  The apnea-ECG database , 2000, Computers in Cardiology 2000. Vol.27 (Cat. 00CH37163).

[4]  S. Redline,et al.  Reliability of scoring respiratory disturbance indices and sleep staging. , 1998, Sleep.

[5]  P. de Chazal,et al.  Automatic classification of sleep apnea epochs using the electrocardiogram , 2000, Computers in Cardiology 2000. Vol.27 (Cat. 00CH37163).

[6]  J. Strackee,et al.  Comparing Spectra of a Series of Point Events Particularly for Heart Rate Variability Data , 1984, IEEE Transactions on Biomedical Engineering.

[7]  Daniel J Buysse,et al.  Sleep–Related Breathing Disorders in Adults: Recommendations for Syndrome Definition and Measurement Techniques in Clinical Research , 2000 .

[8]  Brian D. Ripley,et al.  Pattern Recognition and Neural Networks , 1996 .

[9]  Conor Heneghan,et al.  Heart Rate Variability: Measures and Models , 2000, physics/0008016.

[10]  G. Breithardt,et al.  Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. , 1996 .

[11]  A. Malliani,et al.  Heart rate variability. Standards of measurement, physiological interpretation, and clinical use , 1996 .