Poloxamer-188 Attenuates TBI-Induced Blood–Brain Barrier Damage Leading to Decreased Brain Edema and Reduced Cellular Death

[1]  D. Hovda,et al.  The neurophysiology of concussion. , 2014, Progress in neurological surgery.

[2]  E. Lo,et al.  Kollidon VA64, a Membrane-Resealing Agent, Reduces Histopathology and Improves Functional Outcome after Controlled Cortical Impact in Mice , 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[3]  Michelle C LaPlaca,et al.  Trauma-induced plasmalemma disruptions in three-dimensional neural cultures are dependent on strain modality and rate. , 2011, Journal of neurotrauma.

[4]  Z. Qin,et al.  Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice , 2011, Neuroscience.

[5]  Y. Kang,et al.  Fluid-percussion brain injury induces changes in aquaporin channel expression , 2011, Neuroscience.

[6]  Kevin M. Curtis,et al.  Aquaporin-4 expression in cultured astrocytes after fluid percussion injury. , 2011, Journal of neurotrauma.

[7]  I. Shelef,et al.  Blood-Brain Barrier Breakdown Following Traumatic Brain Injury: A Possible Role in Posttraumatic Epilepsy , 2011, Cardiovascular psychiatry and neurology.

[8]  Alon Friedman,et al.  Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury , 2010, Nature Reviews Neurology.

[9]  L. Puybasset,et al.  Effect of acute poly(ADP-ribose) polymerase inhibition by 3-AB on blood-brain barrier permeability and edema formation after focal traumatic brain injury in rats. , 2010, Journal of neurotrauma.

[10]  R. Vink,et al.  Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments , 2010, Current opinion in neurology.

[11]  R. Hunter,et al.  Poloxamer 188 inhibition of ischemia/reperfusion injury: evidence for a novel anti-adhesive mechanism. , 2010, Annals of clinical and laboratory science.

[12]  Patrick O. Eghwrudjakpor,et al.  Decompressive craniectomy following brain injury: factors important to patient outcome. , 2010, The Libyan journal of medicine.

[13]  Patrick O. Eghwrudjakpor,et al.  Decompressive craniectomy following brain injury: factors important to patient outcome , 2010, The Libyan journal of medicine.

[14]  Tao,et al.  Comparison of labeling methods and time course of traumatic brain injury-induced cell death in mice , 2010 .

[15]  Crystal M. Simon,et al.  Plasma membrane damage as a marker of neuronal injury , 2009, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[16]  A. Verkman,et al.  Glial Cell Aquaporin-4 Overexpression in Transgenic Mice Accelerates Cytotoxic Brain Swelling* , 2008, Journal of Biological Chemistry.

[17]  Shankar Gopinath,et al.  Management of intracranial hypertension. , 2008, Neurologic clinics.

[18]  M. Moskowitz,et al.  Acute Plasmalemma Permeability and Protracted Clearance of Injured Cells after Controlled Cortical Impact in Mice , 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[19]  BenjaminBierbach,et al.  Emboli Formation Rather Than Inflammatory Mediators Are Responsible for Increased Cerebral Water Content After Conventional and Assisted Beating-Heart Myocardial Revascularization in a Porcine Model , 2008 .

[20]  A. Doerfler,et al.  Differentiation of cytotoxic and vasogenic edema in a patient with reversible posterior leukoencephalopathy syndrome using diffusion-weighted MRI. , 2007, Diagnostic and interventional radiology.

[21]  N. Plesnila,et al.  Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-κB transcriptional activity , 2007, Cell Death and Differentiation.

[22]  Anthony Marmarou,et al.  A review of progress in understanding the pathophysiology and treatment of brain edema. , 2007, Neurosurgical focus.

[23]  M. Papadopoulos,et al.  Aquaporins in the Central Nervous System , 2007 .

[24]  R. Haut,et al.  Treatment with the Non-ionic Surfactant Poloxamer P188 Reduces DNA Fragmentation in Cells from Bovine Chondral Explants Exposed to Injurious Unconfined Compression , 2006, Biomechanics and modeling in mechanobiology.

[25]  K. Barbee,et al.  Mechanisms of cell death and neuroprotection by poloxamer 188 after mechanical trauma , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[26]  R. Berman,et al.  Diffusion-weighted imaging of edema following traumatic brain injury in rats: effects of secondary hypoxia. , 2005, Journal of neurotrauma.

[27]  K. Barbee,et al.  The effect of poloxamer-188 on neuronal cell recovery from mechanical injury. , 2005, Journal of neurotrauma.

[28]  P. Kochanek,et al.  Bench-to-bedside review: Apoptosis/programmed cell death triggered by traumatic brain injury , 2004, Critical care.

[29]  刘伟国,et al.  Correlation of cell apoptosis with brain edema and elevated intracranial pressure in traumatic brain injury , 2005 .

[30]  B. Nico,et al.  The role of aquaporin-4 in the blood–brain barrier development and integrity: Studies in animal and cell culture models , 2004, Neuroscience.

[31]  Raphael C. Lee,et al.  Poloxamer 188 prevents acute necrosis of adult skeletal muscle cells following high-dose irradiation. , 2004, Burns : journal of the International Society for Burn Injuries.

[32]  Turgay Dalkara,et al.  Apoptotic and Necrotic Death Mechanisms Are Concomitantly Activated in the Same Cell After Cerebral Ischemia , 2004, Stroke.

[33]  Raphael C. Lee,et al.  Surfactant poloxamer 188-related decreases in inflammation and tissue damage after experimental brain injury in rats. , 2004, Journal of neurosurgery.

[34]  R. Raghupathi,et al.  Cell Death Mechanisms Following Traumatic Brain Injury , 2004, Brain pathology.

[35]  YujiMatsumoto,et al.  Na+/H+ Exchanger Inhibitor, SM-20220, Is Protective Against Excitotoxicity in Cultured Cortical Neurons , 2004 .

[36]  N. Plesnila,et al.  Effect of decompression craniotomy on increase of contusion volume and functional outcome after controlled cortical impact in mice. , 2003, Journal of neurotrauma.

[37]  M. Papadopoulos,et al.  Water transport becomes uncoupled from K+ siphoning in brain contusion, bacterial meningitis, and brain tumours: immunohistochemical case review , 2003, Journal of clinical pathology.

[38]  M. Robbins,et al.  Nuclear factor-kappaB translocation mediates double-stranded ribonucleic acid-induced NIT-1 beta-cell apoptosis and up-regulates caspase-12 and tumor necrosis factor receptor-associated ligand (TRAIL). , 2003, Endocrinology.

[39]  J. P. Schwartz,et al.  Closed-head minimal traumatic brain injury produces long-term cognitive deficits in mice , 2003, Neuroscience.

[40]  C. Honey,et al.  Regulation of aquaporin-4 in a traumatic brain injury model in rats. , 2003, Journal of neurosurgery.

[41]  A. Marmarou,et al.  Pathophysiology of traumatic brain edema: current concepts. , 2003, Acta neurochirurgica. Supplement.

[42]  N. Abbott,et al.  Astrocyte–endothelial interactions and blood–brain barrier permeability * , 2002 .

[43]  N. Abbott Astrocyte–endothelial interactions and blood–brain barrier permeability , 2002, Journal of anatomy.

[44]  W. Poon,et al.  Heterogeneous responses of aquaporin-4 in oedema formation in a replicated severe traumatic brain injury model in rats , 2001, Neuroscience Letters.

[45]  J. DeSimone Focus on "rapid entry of bitter and sweet tastants into liposomes and taste cells: implications for signal transduction". , 2000, American journal of physiology. Cell physiology.

[46]  A S Verkman,et al.  Structure and function of aquaporin water channels. , 2000, American journal of physiology. Renal physiology.

[47]  A. Lentsch,et al.  Activation and Regulation of NFκB during Acute Inflammation , 1999 .

[48]  A. Lentsch,et al.  Activation and regulation of NFkappaB during acute inflammation. , 1999, Clinical chemistry and laboratory medicine.

[49]  P. Agre,et al.  Specialized Membrane Domains for Water Transport in Glial Cells: High-Resolution Immunogold Cytochemistry of Aquaporin-4 in Rat Brain , 1997, The Journal of Neuroscience.

[50]  J. Povlishock,et al.  Traumatically induced altered membrane permeability: its relationship to traumatically induced reactive axonal change. , 1994, Journal of neurotrauma.

[51]  R. Mechoulam,et al.  A nonpsychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury in the rat. , 1993, Journal of neurotrauma.

[52]  Richard T. Linn,et al.  Responses to cortical injury: I. Methodology and local effects of contusions in the rat , 1981, Brain Research.