Polyplexes based on cationic polymers with strong nucleic acid binding properties.
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W. Hennink | R. Schiffelers | G. Storm | S. Pispas | A. K. Varkouhi | T. Lammers | G. Mountrichas | Amir K. Varkouhi
[1] Gert Storm,et al. Endosomal escape pathways for delivery of biologicals. , 2011, Journal of controlled release : official journal of the Controlled Release Society.
[2] W. Hennink,et al. Gene silencing activity of siRNA polyplexes based on biodegradable polymers. , 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[3] W. Hennink,et al. Gene silencing activity of siRNA polyplexes based on thiolated N,N,N-trimethylated chitosan. , 2010, Bioconjugate chemistry.
[4] V. Brower. RNA interference advances to early-stage clinical trials. , 2010, Journal of the National Cancer Institute.
[5] A. Popel,et al. Gene therapy from the perspective of systems biology. , 2010, Current opinion in molecular therapeutics.
[6] M. Rols,et al. Gene Transfer: How Can the Biological Barriers Be Overcome? , 2010, The Journal of Membrane Biology.
[7] Kam W. Leong,et al. Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery , 2010, Journal of The Royal Society Interface.
[8] R. Herzog,et al. Two decades of clinical gene therapy--success is finally mounting. , 2010, Discovery medicine.
[9] T. Kissel,et al. Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging. , 2009, Journal of controlled release : official journal of the Controlled Release Society.
[10] Chantal Pichon,et al. Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers , 2009, British journal of pharmacology.
[11] E. Wagner,et al. Bioresponsive polymers for nonviral gene delivery. , 2009, Current opinion in molecular therapeutics.
[12] Meredith A Mintzer,et al. Nonviral vectors for gene delivery. , 2009, Chemical reviews.
[13] C. Pichon,et al. Polymer-based gene delivery: a current review on the uptake and intracellular trafficking of polyplexes. , 2008, Current gene therapy.
[14] A. Aigner,et al. Polyethylenimine PEI F25-LMW allows the long-term storage of frozen complexes as fully active reagents in siRNA-mediated gene targeting and DNA delivery. , 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[15] Y. Durocher,et al. Opposing Roles of Syndecan-1 and Syndecan-2 in Polyethyleneimine-mediated Gene Delivery* , 2008, Journal of Biological Chemistry.
[16] H. Kung,et al. Synthesis and characterization of folate-PEG-grafted-hyperbranched-PEI for tumor-targeted gene delivery. , 2008, Biochemical and biophysical research communications.
[17] Wim E Hennink,et al. Biodegradable polymers as non-viral carriers for plasmid DNA delivery. , 2008, Journal of controlled release : official journal of the Controlled Release Society.
[18] S. Pispas,et al. Novel double hydrophilic block copolymers based on poly(p‐hydroxystyrene) derivatives and poly(ethylene oxide) , 2007 .
[19] Jo Wixon,et al. Gene therapy clinical trials worldwide to 2007—an update , 2007, The journal of gene medicine.
[20] S-Ja Tseng,et al. Development of poly(amino ester glycol urethane)/siRNA polyplexes for gene silencing. , 2007, Bioconjugate chemistry.
[21] A. Urtti,et al. Polyplex‐mediated gene transfer and cell cycle: effect of carrier on cellular uptake and intracellular kinetics, and significance of glycosaminoglycans , 2007, The journal of gene medicine.
[22] V. Torchilin. Targeted pharmaceutical nanocarriers for cancer therapy and imaging , 2007, The AAPS Journal.
[23] E. Wagner,et al. Cell and Tissue Targeting of Nucleic Acids for Cancer Gene Therapy , 2007, Pharmaceutical Research.
[24] Shubiao Zhang,et al. Toxicity of cationic lipids and cationic polymers in gene delivery. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[25] S. Pispas,et al. Well-Defined Flexible Polyelectrolytes with Two Cationic Sites per Monomeric Unit , 2006 .
[26] J. Ruysschaert,et al. Formation and intracellular trafficking of lipoplexes and polyplexes. , 2005, Molecular therapy : the journal of the American Society of Gene Therapy.
[27] K. Leong,et al. Polyphosphoramidate gene carriers: effect of charge group on gene transfer efficiency , 2004, Gene Therapy.
[28] A. Urtti,et al. Cell‐surface glycosaminoglycans inhibit cation‐mediated gene transfer , 2004, The journal of gene medicine.
[29] A. Klibanov,et al. Non-viral gene therapy: polycation-mediated DNA delivery , 2003, Applied Microbiology and Biotechnology.
[30] W. Guo,et al. Efficient gene delivery via non-covalent complexes of folic acid and polyethylenimine. , 2001, Journal of controlled release : official journal of the Controlled Release Society.
[31] W. Hennink,et al. Copolymers of 2-(dimethylamino)ethyl methacrylate with ethoxytriethylene glycol methacrylate or N-vinyl-pyrrolidone as gene transfer agents. , 2000, Journal of controlled release : official journal of the Controlled Release Society.
[32] Stefaan C. De Smedt,et al. Cationic Polymer Based Gene Delivery Systems , 2000, Pharmaceutical Research.
[33] W. Hennink,et al. Association and Dissociation Characteristics of Polymer/DNA Complexes Used for Gene Delivery , 1999, Pharmaceutical Research.
[34] W. Hennink,et al. Structure-activity relationships of water-soluble cationic methacrylate/methacrylamide polymers for nonviral gene delivery. , 1999, Bioconjugate chemistry.
[35] I. R. Hill,et al. In vitro cytotoxicity of poly(amidoamine)s: relevance to DNA delivery. , 1999, Biochimica et biophysica acta.
[36] M. Ogris,et al. PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery , 1999, Gene Therapy.
[37] H Anholt,et al. Photochemical internalization: a novel technology for delivery of macromolecules into cytosol. , 1999, Cancer research.
[38] W. Hennink,et al. Relation between transfection efficiency and cytotoxicity of poly(2-(dimethylamino)ethyl methacrylate)/plasmid complexes , 1997 .
[39] W. Hennink,et al. Effect of Size and Serum Proteins on Transfection Efficiency of Poly ((2-dimethylamino)ethyl Methacrylate)-Plasmid Nanoparticles , 1996, Pharmaceutical Research.
[40] J Moan,et al. INTRACELLULAR LOCALIZATION OF SULFONATED meso‐TETRAPHENYLPORPHINES IN A HUMAN CARCINOMA CELL LINE * , 1990, Photochemistry and photobiology.
[41] D. Scudiero,et al. Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. , 1988, Cancer research.
[42] C. Cho,et al. Biodegradable polymer-mediated sh/siRNA delivery for cancer studies. , 2010, Methods in molecular biology.
[43] T. Park,et al. Comparative evaluation of target-specific GFP gene silencing efficiencies for antisense ODN, synthetic siRNA, and siRNA plasmid complexed with PEI-PEG-FOL conjugate. , 2006, Bioconjugate chemistry.