Longitudinal serum S100β and brain aging in the Lothian Birth Cohort 1936

[1]  R. Anderson,et al.  High Serum S100B Levels for Trauma Patients without Head Injuries , 2001, Neurosurgery.

[2]  C. Beaulieu,et al.  The basis of anisotropic water diffusion in the nervous system – a technical review , 2002, NMR in biomedicine.

[3]  J. Wardlaw,et al.  Blood-brain barrier failure as a core mechanism in cerebral small vessel disease and dementia: evidence from a cohort study , 2017, Alzheimer's & Dementia.

[4]  J. van os,et al.  Serum S100B: A proxy marker for grey and white matter status in the absence and presence of (increased risk of) psychotic disorder? , 2017, PloS one.

[5]  Karen J. Ferguson,et al.  Enlarged Perivascular Spaces on MRI Are a Feature of Cerebral Small Vessel Disease , 2010, Stroke.

[6]  K. Tziridis,et al.  S100B in serum and saliva: a valid invasive or non-invasive biomarker in obstructive sleep apnea? , 2016, European review for medical and pharmacological sciences.

[7]  Peng Yuan,et al.  Regional brain shrinkage over two years: Individual differences and effects of pro-inflammatory genetic polymorphisms , 2014, NeuroImage.

[8]  L. Wilkins What are White Matter Hyperintensities Made of? , 2016, Journal of the American Heart Association.

[9]  Thomas R. Knösche,et al.  White matter integrity, fiber count, and other fallacies: The do's and don'ts of diffusion MRI , 2013, NeuroImage.

[10]  Paul M. Thompson,et al.  Systemic inflammation as a predictor of brain aging: Contributions of physical activity, metabolic risk, and genetic risk , 2018, NeuroImage.

[11]  P. Hofman,et al.  Blood–brain barrier leakage is more widespread in patients with cerebral small vessel disease , 2017, Neurology.

[12]  E. Thompson,et al.  Cerebrospinal fluid (CSF) and serum S100B: release and wash-out pattern , 2003, Brain Research Bulletin.

[13]  F. Michetti,et al.  Pediatric concentrations of S100B protein in blood: age- and sex-related changes. , 2003, Clinical chemistry.

[14]  B. Romner,et al.  Biochemical serum markers of traumatic brain injury. , 2002, The Journal of trauma.

[15]  B. Romner,et al.  Age- and Sex-Related Changes of S-100 Protein Concentrations in Cerebrospinal Fluid and Serum in Patients with No Previous History of Neurological Disorder , 1997 .

[16]  H. Sauer,et al.  Serum S100B Protein is Specifically Related to White Matter Changes in Schizophrenia , 2016, Front. Cell. Neurosci..

[17]  R. Donato,et al.  Functions of S100 proteins. , 2012, Current molecular medicine.

[18]  M. Schroeter,et al.  Glial pathology is modified by age in mood disorders--a systematic meta-analysis of serum S100B in vivo studies. , 2011, Journal of affective disorders.

[19]  R. Harpio,et al.  S100 proteins as cancer biomarkers with focus on S100B in malignant melanoma. , 2004, Clinical biochemistry.

[20]  Joanna M. Wardlaw,et al.  Vascular risk factors and progression of white matter hyperintensities in the Lothian Birth Cohort 1936 , 2016, Neurobiology of Aging.

[21]  M. Wiesmann,et al.  Plasma S-100b protein concentration in healthy adults is age- and sex-independent. , 1998, Clinical Chemistry.

[22]  Emma J. Telford,et al.  A latent measure explains substantial variance in white matter microstructure across the newborn human brain , 2017, Brain Structure and Function.

[23]  Yves Rosseel,et al.  lavaan: An R Package for Structural Equation Modeling , 2012 .

[24]  G. Borm,et al.  Age-related changes of neuron-specific enolase, S-100 protein, and myelin basic protein concentrations in cerebrospinal fluid. , 1992, Clinical chemistry.

[25]  Joanna M Wardlaw,et al.  What are White Matter Hyperintensities Made of? , 2015, Journal of the American Heart Association.

[26]  I. Deary,et al.  Brain Aging, Cognition in Youth and Old Age and Vascular Disease in the Lothian Birth Cohort 1936: Rationale, Design and Methodology of the Imaging Protocol* , 2011, International journal of stroke : official journal of the International Stroke Society.

[27]  P. Schoenknecht,et al.  First evidence for glial pathology in late life minor depression: S100B is increased in males with minor depression , 2015, Front. Cell. Neurosci..

[28]  Alan C. Evans,et al.  A voxel-based morphometric study to determine individual differences in gray matter density associated with age and cognitive change over time. , 2004, Cerebral cortex.

[29]  P. Visscher,et al.  The Lothian Birth Cohort 1936: a study to examine influences on cognitive ageing from age 11 to age 70 and beyond , 2007, BMC geriatrics.

[30]  Enrico Pellegrini,et al.  Application of the Ordered Logit Model to Optimising Frangi Filter Parameters for Segmentation of Perivascular Spaces , 2016, MIUA.

[31]  F. Paul,et al.  Perivascular spaces--MRI marker of inflammatory activity in the brain? , 2008, Brain : a journal of neurology.

[32]  R. Schmidhammer,et al.  Circulating S100B is increased after bilateral femur fracture without brain injury in the rat. , 2003, British journal of anaesthesia.

[33]  R. Donato,et al.  Intracellular and extracellular roles of S100 proteins , 2003, Microscopy research and technique.

[34]  Ian J Deary,et al.  Cohort profile: the Lothian Birth Cohorts of 1921 and 1936. , 2012, International journal of epidemiology.

[35]  Joanna M. Wardlaw,et al.  Quantifying the effects of normal ageing on white matter structure using unsupervised tract shape modelling , 2010, NeuroImage.

[36]  Jacob Cohen,et al.  A power primer. , 1992, Psychological bulletin.

[37]  A. Fabio,et al.  S100b as a prognostic biomarker in outcome prediction for patients with severe traumatic brain injury. , 2013, Journal of neurotrauma.

[38]  R. Sherwood,et al.  Serum S100β protein as a marker of disease activity in patients with malignant melanoma , 2001 .

[39]  Amos Storkey,et al.  TractoR: Magnetic Resonance Imaging and Tractography with R , 2011 .

[40]  T. Beems,et al.  GFAP and S100B are biomarkers of traumatic brain injury , 2010, Neurology.

[41]  J Perl,et al.  Serum S-100β as a possible marker of blood–brain barrier disruption , 2002, Brain Research.

[42]  J. Wardlaw,et al.  Cerebral Perivascular Spaces Visible on Magnetic Resonance Imaging: Development of a Qualitative Rating Scale and its Observer Reliability , 2015, Cerebrovascular Diseases.

[43]  Susana Muñoz Maniega,et al.  Coupled Changes in Brain White Matter Microstructure and Fluid Intelligence in Later Life , 2015, The Journal of Neuroscience.

[44]  Joanna M. Wardlaw,et al.  A General Factor of Brain White Matter Integrity Predicts Information Processing Speed in Healthy Older People , 2010, The Journal of Neuroscience.

[45]  Karen J. Ferguson,et al.  New multispectral MRI data fusion technique for white matter lesion segmentation: method and comparison with thresholding in FLAIR images , 2010, European Radiology.

[46]  Mark E Bastin,et al.  Ageing and brain white matter structure in 3,513 UK Biobank participants , 2016, Nature Communications.

[47]  Hammad Naveed,et al.  The effect of systemic inflammation on human brain barrier function , 2017, Brain, Behavior, and Immunity.

[48]  A. Villringer,et al.  Validating Serum S100B and Neuron-Specific Enolase as Biomarkers for the Human Brain – A Combined Serum, Gene Expression and MRI Study , 2012, PloS one.

[49]  M. Wiesmann,et al.  Measurement of glial fibrillary acidic protein in human blood: analytical method and preliminary clinical results. , 1999, Clinical chemistry.

[50]  E. Peskind,et al.  Cerebrospinal fluid S100B is elevated in the earlier stages of Alzheimer's disease , 2001, Neurochemistry International.

[51]  C. Sudlow,et al.  Enlarged perivascular spaces and cerebral small vessel disease , 2013, International journal of stroke : official journal of the International Stroke Society.

[52]  J. Mcardle Latent variable modeling of differences and changes with longitudinal data. , 2009, Annual review of psychology.

[53]  Jason K. W. Lee,et al.  S100B as a Marker for Brain Damage and Blood–Brain Barrier Disruption Following Exercise , 2014, Sports Medicine.

[54]  M. Buchfelder,et al.  The Passage of S100B from Brain to Blood Is Not Specifically Related to the Blood-Brain Barrier Integrity , 2010, Cardiovascular psychiatry and neurology.

[55]  E. Thelin,et al.  A review of the clinical utility of serum S100B protein levels in the assessment of traumatic brain injury , 2016, Acta Neurochirurgica.

[56]  P. Abreu-González,et al.  Summer/winter changes in serum S100B protein concentration as a source of research variance. , 2013, Journal of psychiatric research.

[57]  J. Wang,et al.  Study on adhesion, proliferation and differentiation of osteoblasts promoted by new absorbable bioactive glass injection in vitro. , 2016, European review for medical and pharmacological sciences.

[58]  Benjamin S Aribisala,et al.  Circulating Inflammatory Markers Are Associated With Magnetic Resonance Imaging-Visible Perivascular Spaces But Not Directly With White Matter Hyperintensities , 2014, Stroke.

[59]  D. Souza,et al.  Serum levels of S100B and NSE proteins in Alzheimer's disease patients , 2010, Journal of Neuroinflammation.

[60]  Flávio Kapczinski,et al.  The serum S100B concentration is age dependent. , 2002, Clinical chemistry.

[61]  Cathie Sudlow,et al.  Lacunar stroke is associated with diffuse blood–brain barrier dysfunction , 2009, Annals of neurology.

[62]  Nancy L. Pedersen,et al.  Biological Age Predictors , 2017, EBioMedicine.

[63]  Taku Komura,et al.  Medical Image Understanding and Analysis (MIUA 2017) , 2017 .

[64]  Nick C Fox,et al.  Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration , 2013, The Lancet Neurology.

[65]  L. Dosemeci,et al.  Comparison of serum and cerebrospinal fluid protein S-100b levels after severe head injury and their prognostic importance. , 2004, The Journal of trauma.

[66]  J. Schafer,et al.  Missing data: our view of the state of the art. , 2002, Psychological methods.

[67]  S. Mocellin,et al.  The prognostic value of serum S100B in patients with cutaneous melanoma: A meta‐analysis , 2008, International journal of cancer.

[68]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .

[69]  V. Arolt,et al.  S100B in brain damage and neurodegeneration , 2003, Microscopy research and technique.