Patient factors associated with hospital discharge to care facility following critical illness

Background— Many critically ill (CI) patients are transferred to other care facilities instead of to home at hospital discharge. Objective— To identify patient factors associated with hospital discharge to care facility following CI, and to estimate the magnitude of risk associated with each factor. Methods— Retrospective cohort study conducted in a medical intensive care unit. We studied 548 survivors of CI. Multivariable logistic regression was employed to identify independent risk factors for discharge to care facility. Only the first 72 hours of intensive care were analyzed. Results— Approximately one-quarter of the survivors of CI were discharged to a care facility instead of to home (143/548, 26.1%). This event occurred more commonly in older patients, even after adjustment for severity of illness and comorbidities (odds ratio [OR] 1.8 for patients ≥ 65 years of age versus patients < 65 years; 95% confidence interval [CI] 1.1–3.1, p=0.02). The risk was greatest for patients who received mechanical ventilation (OR 3.4; 95% CI 2.0–5.8; p<0.001) or had hospitalizations characterized by severe cognitive dysfunction (OR 8.1; 95% CI 1.3–50.6; p=0.02) or poor strength and/or mobility (OR 31.7; 95% CI 6.4–157.3; p<0.001). The model showed good discrimination (area under Conclusion— Our model, which did not include baseline function or social variables, provided good discrimination between patients discharged to care facility following CI and patients discharged to home. These results suggest that future research should focus on the debilitating effects of respiratory failure and on conditions with cognitive and neuromuscular sequelae. we conducted a retrospective We performed a multivariable analysis and estimated the magnitude associated with We further hypothesized that the discrimination of the to changes in length of stay.

[1]  R. Balk Age, Duration of Mechanical Ventilation, and Outcomes of Patients Who Are Critically Ill , 2010 .

[2]  S. Douglas,et al.  Composite outcomes of chronically critically ill patients 4 months after hospital discharge. , 2009, American journal of critical care : an official publication, American Association of Critical-Care Nurses.

[3]  Timothy J. Brennan,et al.  Early physical and occupational therapy in mechanically ventilated , critically ill patients : A randomised controlled trial , 2009 .

[4]  T. Murphy,et al.  Characteristics associated with delirium in older patients in a medical intensive care unit. , 2007, Archives of internal medicine.

[5]  C. Winkelman Inactivity and inflammation in the critically ill patient. , 2007, Critical care clinics.

[6]  A. E. El Solh,et al.  Overview of Respiratory Failure in Older Adults , 2006, Journal of intensive care medicine.

[7]  Sandra L. Peake,et al.  The effect of obesity on 12-month survival following admission to intensive care: A prospective study* , 2006, Critical care medicine.

[8]  E. Marcantonio,et al.  Nursing home patients in the intensive care unit: Risk factors for mortality , 2006, Critical care medicine.

[9]  J. Friedrich,et al.  Long-term outcomes and clinical predictors of hospital mortality in very long stay intensive care unit patients: a cohort study , 2006, Critical care.

[10]  Daniel J. Johnson,et al.  Hospital discharge to care facility: a patient-centered outcome for the evaluation of intensive care for octogenarians. , 2004, Chest.

[11]  R. Jaeschke,et al.  A readers' guide to the interpretation of diagnostic test properties: clinical example of sepsis , 2003, Intensive Care Medicine.

[12]  E. Ely,et al.  Six-month neuropsychological outcome of medical intensive care unit patients , 2003, Critical care medicine.

[13]  Arthur S Slutsky,et al.  One-year outcomes in survivors of the acute respiratory distress syndrome. , 2003, The New England journal of medicine.

[14]  R. Kakuma,et al.  Predictors of functional decline in hospitalized elderly patients: a systematic review. , 2002, The journals of gerontology. Series A, Biological sciences and medical sciences.

[15]  P. Bach,et al.  The epidemiology and costs of chronic critical illness. , 2002, Critical care clinics.

[16]  C B Schechter,et al.  Outcome prediction model for very elderly critically ill patients , 2001, Critical care medicine.

[17]  R. Griffiths,et al.  Memory, delusions, and the development of acute posttraumatic stress disorder-related symptoms after intensive care , 2001, Critical care medicine.

[18]  W G Weissert,et al.  Predicting Elderly People’s Risk for Nursing Home Placement, Hospitalization, Functional Impairment, and Mortality: A Synthesis , 2000, Medical care research and review : MCRR.

[19]  M. Kollef,et al.  Clinical predictors and outcomes for patients requiring tracheostomy in the intensive care unit. , 1999, Critical care medicine.

[20]  Christianna S. Williams,et al.  The combined effects of baseline vulnerability and acute hospital events on the development of functional dependence among community-living older persons. , 1999, The journals of gerontology. Series A, Biological sciences and medical sciences.

[21]  C. Brun-Buisson,et al.  Reduced quality of life in survivors of acute respiratory distress syndrome compared with critically ill control patients. , 1999, JAMA.

[22]  C. Welsh,et al.  Long‐Term Functional Outcome After Intensive Care , 1999, Journal of the American Geriatrics Society.

[23]  C. Stoutenbeek,et al.  Systematic review of early prediction of poor outcome in anoxicischaemic coma , 1998, The Lancet.

[24]  I. L. Cohen,et al.  Clinical and economic outcome of mechanically ventilated patients in New York State during 1993: analysis of 10,473 cases under DRG 475. , 1998, Chest.

[25]  J Concato,et al.  Importance of functional measures in predicting mortality among older hospitalized patients. , 1998, JAMA.

[26]  Claude Bouchard,et al.  Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults. , 1998, WMJ : official publication of the State Medical Society of Wisconsin.

[27]  G. Troché,et al.  Is the duration of mechanical ventilation predictable? , 1997, Chest.

[28]  J Zhang,et al.  Risk factors for nursing home use after hospitalization for medical illness. , 1996, The journals of gerontology. Series A, Biological sciences and medical sciences.

[29]  Frank E. Harrell,et al.  Identification of Comatose Patients at High Risk for Death or Severe Disability , 1995 .

[30]  W. Knaus,et al.  Predicting Future Functional Status for Seriously Ill Hospitalized Adults: The SUPPORT Prognostic Model , 1995, Annals of Internal Medicine.

[31]  M. Dolgin,et al.  Nomenclature and Criteria for Diagnosis of Diseases of the Heart and Great Vessels , 1994 .

[32]  M R Pinsky,et al.  Long-term outcome of critically ill elderly patients requiring intensive care. , 1993, JAMA.

[33]  M. Delgado-Rodríguez,et al.  Factors related to quality of life 12 months after discharge from an intensive care unit , 1992, Critical care medicine.

[34]  W. Knaus,et al.  The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults. , 1991, Chest.

[35]  R. Oye,et al.  Predictors of Mortality in Older Patients following Medical Intensive Care: The Importance of Functional Status , 1991, Journal of the American Geriatrics Society.

[36]  C. Mackenzie,et al.  A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. , 1987, Journal of chronic diseases.

[37]  P. Robinson The interpretation of diagnostic tests. , 1987, Nuclear medicine communications.

[38]  E. Draper,et al.  APACHE II: A severity of disease classification system , 1985, Critical care medicine.

[39]  B. Jennett,et al.  Assessment of coma and impaired consciousness. A practical scale. , 1974, Lancet.