Startle potentiation in aversive anticipation: evidence for state but not trait effects.

The present study was undertaken to determine whether aversiveness contributes to startle potentiation in anticipation of affective pictures above and beyond the effects of emotional arousal. Further, participants high in trait anxious apprehension, which is characterized by worry about the future, were expected to show especially pronounced anticipatory startle responses. Startle blink reflex was measured during warning stimuli that predicted the valence of ensuing aversive/unpleasant, pleasant, or neutral pictures. Startle magnitude was larger in anticipation of aversive than of pleasant pictures and smallest in anticipation of neutral pictures. Enhanced startle potentiation was not found in anxious apprehension subjects. These data suggest that the aversive nature of stimuli contribute to the potentiation of startle above and beyond the effects of emotional arousal, which may be a universal phenomenon not modulated by individual differences.

[1]  C. Grillon,et al.  Fear-potentiated startle: Relationship to the level of state/trait anxiety in healthy subjects , 1993, Biological Psychiatry.

[2]  Gregory A. Miller,et al.  Anxiety, stress, and cortical brain function. , 2000 .

[3]  T J Meyer,et al.  Development and validation of the Penn State Worry Questionnaire. , 1990, Behaviour research and therapy.

[4]  P. Lang.  International Affective Picture System (IAPS) : Technical Manual and Affective Ratings , 1995 .

[5]  R A McCormick,et al.  Testing a tripartite model: I. Evaluating the convergent and discriminant validity of anxiety and depression symptom scales. , 1995, Journal of abnormal psychology.

[6]  C. Grillon,et al.  Acoustic startle and anticipatory anxiety in humans: effects of monaural right and left ear stimulation. , 1995, Psychophysiology.

[7]  C. Patrick,et al.  Startle potentiation during anticipation of a noxious stimulus: active versus passive response sets. , 1995, Psychophysiology.

[8]  M. Bradley,et al.  Affective startle modulation in anticipation and perception. , 2001, Psychophysiology.

[9]  A. Siegel.  Stimulus generalization of a classically conditioned response along a temporal dimension. , 1967, Journal of comparative and physiological psychology.

[10]  D. Marlowe,et al.  The Approval Motive: Studies in Evaluative Dependence , 1980 .

[11]  Jeffrey B. Henriques,et al.  While a phobic waits: regional brain electrical and autonomic activity in social phobics during anticipation of public speaking , 2000, Biological Psychiatry.

[12]  O V Lipp,et al.  The effect of warning stimulus modality on blink startle modification in reaction time tasks. , 2000, Psychophysiology.

[13]  A. van Boxtel,et al.  Optimal EMG signal bandwidth and interelectrode distance for the recording of acoustic, electrocutaneous, and photic blink reflexes. , 1998, Psychophysiology.

[14]  K Merikangas,et al.  Measuring the time course of anticipatory anxiety using the fear-potentiated startle reflex. , 1993, Psychophysiology.

[15]  Richard Davidson,et al.  Affective modulation of eyeblink startle with reward and threat. , 2002, Psychophysiology.

[16]  M. Davis,et al.  Temporal specificity of fear conditioning: effects of different conditioned stimulus-unconditioned stimulus intervals on the fear-potentiated startle effect. , 1989, Journal of experimental psychology. Animal behavior processes.

[17]  J F Thayer,et al.  Phasic heart period reactions to cued threat and nonthreat stimuli in generalized anxiety disorder. , 2000, Psychophysiology.

[18]  K Merikangas,et al.  Fear-potentiated startle in humans: effects of anticipatory anxiety on the acoustic blink reflex. , 1991, Psychophysiology.