Neurological signs described at the Federal University of Rio de Janeiro: connecting the past to the future.

OBJECTIVE The Federal University of Rio de Janeiro (UFRJ) is one of the pillars of Brazilian Medicine and, in Neurology, has always shown prominence, with notable professors such as Antônio Austregésilo and Deolindo Couto. Historically, practitioners of the UFRJ Medical School have discovered neurological signs that, although used in medical and academic practice, have never been published. Our aim was to bring these signs to the forefront so that they become properly recognized and studied. METHODS We conducted our search by questioning 49 professors and physicians by e-mail about neurological signs that they remembered having had contact with at UFRJ. RESULTS We report on the unpublished pillow sign in progressive supranuclear palsy; the Brazilian sandal sign in functional or malingering patients; the dermographism sign in acute meningitis; the reverse forearm rolling sign in functional palsies; the cycling maneuver in parkinsonian syndromes and the Sá Cavalcanti sign, a Babinski equivalent. We have also recollected the following published signs for their historical relevance: the Austregésilo sign (Antônio Austregésilo), another Babinski equivalent; the digiti quinti rolling sign in subtle palsies (Péricles Maranhão) and the digiti quinti sign in hemiplegic migraine (Maurice Vincent). These signs are easily reproduced and have potential clinical applicability, deserving to be more thoroughly studied. CONCLUSIONS Through a qualitative methodology, we have identified six original unpublished neurological signs known by the academic community, establishing the contribution of these individuals to the expansion of neurological semiology.

[1]  E. Diamandis,et al.  The emerging landscape of scientific publishing. , 2017, Clinical biochemistry.

[2]  Y. Péréon,et al.  The Babinski sign , 2017, The Lancet Neurology.

[3]  S. Seo,et al.  Research Methods in Healthcare Epidemiology: Survey and Qualitative Research , 2016, Infection Control & Hospital Epidemiology.

[4]  R. Munhoz,et al.  Jean-Baptiste Charcot in Rio de Janeiro: glamorous trip and celebrity in 1908. , 2015, Arquivos de neuro-psiquiatria.

[5]  E. Wilson Aloysio de Castro and Uruguay. , 2015, Arquivos de neuro-psiquiatria.

[6]  P. Maranhão-Filho,et al.  Neurological examination: pioneering authors and their books. , 2015, Arquivos de neuro-psiquiatria.

[7]  E. Engelhardt,et al.  French school of neurology in the 19th and first half of the 20th century, and its influence in Brazil. , 2013, Arquivos de neuro-psiquiatria.

[8]  E. Engelhardt,et al.  The first Brazilian neuropsychiatrist, José Martins da Cruz Jobim, tuberculous meningitis and mental disease. , 2013, Arquivos de neuro-psiquiatria.

[9]  M. D. Gomes,et al.  The Brazilian Neurology centenary (1912-2012) and the common origin of the fields of Neurology and Psychiatry. , 2013, Arquivos de neuro-psiquiatria.

[10]  Peter Brown,et al.  Hypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's disease. , 2012, Brain : a journal of neurology.

[11]  R. Luiz,et al.  The digiti quinti sign in hemiplegic migraine , 2011, Cephalalgia : an international journal of headache.

[12]  A. Kalantri,et al.  Accuracy of physical signs for detecting meningitis: A hospital-based diagnostic accuracy study , 2010, Clinical Neurology and Neurosurgery.

[13]  P. Maranhão-Filho,et al.  Can Clinical Tests Detect Early Signs of Monohemispheric Brain Tumors? , 2010, Journal of neurologic physical therapy : JNPT.

[14]  M. Vincent A Note on the Digiti Quinti Sign in Hemiplegic Migraine , 2009, Cephalalgia : an international journal of headache.

[15]  S. Mackinnon,et al.  Scratch collapse test for evaluation of carpal and cubital tunnel syndrome. , 2008, The Journal of hand surgery.

[16]  B. Dubois,et al.  “Applause sign” helps to discriminate PSP from FTD and PD , 2005, Neurology.

[17]  S. Gusmão,et al.  The Early History of Neurosurgery in Brazil , 2002, Neurosurgery.

[18]  H. Teive,et al.  [Professor Antonio Austregésilo. The pioneer of neurology and of the study of movement disorders in Brazil]. , 1999, Arquivos de neuro-psiquiatria.

[19]  R. Melaragno Filho,et al.  [In memoriam: Deolindo Augusto de Nunes Couto (1902-1992)]. , 1992, Arquivos de neuro-psiquiatria.

[20]  M. Alter The digiti quinti sign of mild hemiparesis , 1973, Neurology.

[21]  R. Wartenberg THE BABINSKI REFLEX AFTER FIFTY YEARS , 1947 .