Ti(Oi-Pr)4-promoted photoenolization Diels–Alder reaction to construct polycyclic rings and its synthetic applications

[1]  A. Kutateladze,et al.  Oxazolines as Dual‐Function Traceless Chromophores and Chiral Auxiliaries: Enantioselective Photoassisted Synthesis of Polyheterocyclic Ketones. , 2016 .

[2]  A. Kutateladze,et al.  Photoassisted Synthesis of Complex Molecular Architectures: Dearomatization of Benzenoid Arenes with Aza-o-xylylenes via an Unprecedented [2+4] Reaction Topology. , 2016, Angewandte Chemie.

[3]  M. Kärkäs,et al.  Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis , 2016, Chemical reviews.

[4]  L. Overman,et al.  Synthetic Strategies toward Natural Products Containing Contiguous Stereogenic Quaternary Carbon Atoms. , 2016, Angewandte Chemie.

[5]  K. Nicolaou,et al.  Total Synthesis of Trioxacarcins DC-45-A1, A, D, C, and C7″-epi-C and Full Structural Assignment of Trioxacarcin C. , 2016, Journal of the American Chemical Society.

[6]  A. Kutateladze,et al.  Oxazolines as Dual-Function Traceless Chromophores and Chiral Auxiliaries: Enantioselective Photoassisted Synthesis of Polyheterocyclic Ketones. , 2016, Journal of the American Chemical Society.

[7]  L. Dell’Amico,et al.  Enantioselective Organocatalytic Diels–Alder Trapping of Photochemically Generated Hydroxy‐o‐Quinodimethanes , 2016, Angewandte Chemie.

[8]  Jianxian Gong,et al.  Direct construction of vicinal all-carbon quaternary stereocenters in natural product synthesis. , 2015, Natural product reports.

[9]  A. Kutateladze,et al.  Amino Azaxylylenes Photogenerated from o-Amido Imines: Photoassisted Access to Complex Spiro-Poly-Heterocycles. , 2015, Angewandte Chemie.

[10]  K. Nicolaou,et al.  Total synthesis of trioxacarcin DC-45-A2. , 2015, Angewandte Chemie.

[11]  K. Nicolaou,et al.  Total synthesis of myceliothermophins C, D, and E. , 2014, Angewandte Chemie.

[12]  Andrew G Myers,et al.  The evolving role of chemical synthesis in antibacterial drug discovery. , 2014, Angewandte Chemie.

[13]  D. Trauner,et al.  Intramolecular Vinyl Quinone Diels—Alder Reactions: Asymmetric Entry to the Cordiachrome Core and Synthesis of (—)‐Isoglaziovianol. , 2014 .

[14]  C. Barner‐Kowollik,et al.  Light induced DNA-protein conjugation. , 2013, Chemical communications.

[15]  C. Donner.  Tandem Michael—Dieckmann/Claisen Reaction of ortho‐Toluates — The Staunton—Weinreb Annulation , 2013 .

[16]  A. Kutateladze,et al.  Photoassisted synthesis of enantiopure alkaloid mimics possessing unprecedented polyheterocyclic cores. , 2013, Journal of the American Chemical Society.

[17]  C. Donner.  Tandem Michael–Dieckmann/Claisen reaction of ortho-toluates—the Staunton–Weinreb annulation , 2013 .

[18]  C. Farés,et al.  The cinchona primary amine-catalyzed asymmetric epoxidation and hydroperoxidation of α,β-unsaturated carbonyl compounds with hydrogen peroxide. , 2013, Journal of the American Chemical Society.

[19]  Changwei Hu,et al.  A theoretical investigation on the Strecker reaction catalyzed by a Ti(IV)-complex catalyst generated from a cinchona alkaloid, achiral substituted 2,2'-biphenol, and tetraisopropyl titanate. , 2013, Chemistry.

[20]  H. Hashimoto,et al.  The first total synthesis of hibarimicinone, a potent v-Src tyrosine kinase inhibitor , 2012 .

[21]  P. Wright,et al.  Methodological Advances Permit the Stereocontrolled Construction of Diverse Fully Synthetic Tetracyclines Containing an All-Carbon Quaternary Center at Position C5a. , 2011, Tetrahedron.

[22]  K. Shin‐ya,et al.  Naphthoquinone-like polyketide isolated from Streptomyces sp. RI-77 and its predicted biosynthetic pathway. , 2011, Journal of natural products.

[23]  A. Kutateladze,et al.  Rapid photoassisted access to N,O,S-polyheterocycles with benzoazocine and hydroquinoline cores: intramolecular cycloadditions of photogenerated azaxylylenes. , 2011, Angewandte Chemie.

[24]  Robert M. Williams,et al.  Synthetic Studies on the Ambiguine Family of Alkaloids: Construction of the ABCD Ring System. , 2011, Tetrahedron letters.

[25]  D. Trauner,et al.  Synthetic studies toward A-74528. , 2011, Organic letters.

[26]  K. Nicolaou,et al.  Recent advances in the chemistry and biology of naturally occurring antibiotics. , 2009, Angewandte Chemie.

[27]  A. Howell,et al.  Synthesis of epi-oxetin via a serine-derived 2-methyleneoxetane. , 2008, The Journal of organic chemistry.

[28]  L. Overman,et al.  Total synthesis of complex cyclotryptamine alkaloids: stereocontrolled construction of quaternary carbon stereocenters. , 2007, Angewandte Chemie.

[29]  Pallab Pahari,et al.  Recent advances in the Hauser annulation. , 2007, Chemical reviews.

[30]  M. Brimble,et al.  Use of Stabilized Phthalide Anion Annulation Reactions in Synthesis: An Update , 2007 .

[31]  G. Dudley,et al.  Tandem nucleophilic addition/fragmentation reactions and synthetic versatility of vinylogous acyl triflates. , 2006, Journal of the American Chemical Society.

[32]  M. Yus,et al.  In the arena of enantioselective synthesis, titanium complexes wear the laurel wreath. , 2006, Chemical reviews.

[33]  P. Wagner,et al.  Electronic effects of ring substituents on triplet benzylic biradicals. , 2006, Organic letters.

[34]  R. Munakata,et al.  Recent advances in natural product synthesis by using intramolecular Diels-Alder reactions. , 2005, Chemical reviews.

[35]  Y. Fujita,et al.  Structural elucidation of A-74528, an inhibitor for 2',5'-phosphodiesterase isolated from Streptomyces sp. , 2005, Bioorganic & medicinal chemistry letters.

[36]  Andrew G Myers,et al.  A Convergent Enantioselective Route to Structurally Diverse 6-Deoxytetracycline Antibiotics , 2005, Science.

[37]  K. Nicolaou,et al.  Total synthesis of hamigerans and analogues thereof. Photochemical generation and Diels-Alder trapping of hydroxy-o-quinodimethanes. , 2004, Journal of the American Chemical Society.

[38]  K. Nicolaou,et al.  Total synthesis of hybocarpone and analogues thereof. A facile dimerization of naphthazarins to pentacyclic systems. , 2004, Journal of the American Chemical Society.

[39]  W. Massa,et al.  Highly enantioselective Diels-Alder reaction of a photochemically generated o-quinodimethane with olefins. , 2003, Angewandte Chemie.

[40]  Tamsyn Montagnon,et al.  The Diels--Alder reaction in total synthesis. , 2002, Angewandte Chemie.

[41]  J. Galano,et al.  A stereocontrolled approach towards highly oxygenated taxane C and CD-ring precursors , 2002 .

[42]  K. Nicolaou,et al.  Total Synthesis of Hamigerans. Part 1. Development of Synthetic Technology for the Construction of Benzannulated Polycyclic Systems by the Intramolecular Trapping of Photogenerated Hydroxy-o-quinodimethanes and Synthesis of Key Building Blocks. , 2002 .

[43]  K. Nicolaou,et al.  Total Synthesis of Hamigerans. Part 2. Implementation of the Intramolecular Diels—Alder Trapping of Photochemically Generated Hydroxy-o-quinodimethanes; Strategy and Completion of the Synthesis. , 2002 .

[44]  P. Wagner,et al.  Light-induced decarboxylation of (o-acylphenyl)acetic acids. , 2002, Organic letters.

[45]  K. Nicolaou,et al.  Total Synthesis of Hamigerans: Part 1. Development of Synthetic Technology for the Construction of Benzannulated Polycyclic Systems by the Intramolecular Trapping of Photogenerated Hydroxy-o-quinodimethanes and Synthesis of Key Building Blocks This work was financially supported by the National Inst , 2001, Angewandte Chemie.

[46]  K. Nicolaou,et al.  Total Synthesis of Hamigerans: Part 2. Implementation of the Intramolecular Diels-Alder Trapping of Photochemically Generated Hydroxy-o-quinodimethanes; Strategy and Completion of the Synthesis This work was financially supported by the National Institutes of Health (USA) and The Skaggs Institute fo , 2001, Angewandte Chemie.

[47]  K. Nicolaou,et al.  Total Synthesis of Hybocarpone , 2001 .

[48]  J. Segura,et al.  o‐Quinodimethanes: Efficient Intermediates in Organic Synthesis , 2000 .

[49]  J. Segura,et al.  o-Quinodimethanes: Efficient Intermediates in Organic Synthesis. , 1999, Chemical reviews.

[50]  Monte,et al.  Glaziovianol, a new terpenoid hydroquinone from auxemma glazioviana , 1999, Journal of natural products.

[51]  F. Renz,et al.  A Novel Hetero‐Diels—Alder Approach Towards Perhydro Quinolinones Bearing an Angular Methyl Group. , 1998 .

[52]  P. Wagner,et al.  The photochemistry of o-benzylbenzophenone: a pericyclic cornucopia , 1998 .

[53]  T. Durst,et al.  Photochemically generated bicyclic ortho-quinodimethanes: Photo-enolization of bicyclic aldehydes and ketones , 1997 .

[54]  F. Zunino,et al.  New developments in antitumor anthracyclines. , 1997, Pharmacology & therapeutics.

[55]  J. Winkler.  Tandem Diels−Alder Cycloadditions in Organic Synthesis , 1996 .

[56]  O. Pessoa.  Cordiachromes from Auxemma oncocalyx , 1995 .

[57]  A. Mitchell,et al.  Annulation reactions with stabilized phthalide anions , 1995 .

[58]  A. Griesbeck,et al.  ω-Hyroxy-ortho-quinodimethane: Trapping with Trifluoroacetone and Photocyclization. , 1994 .

[59]  A. Griesbeck,et al.  ω‐Hydroxy‐ortho‐quinodimethane: trapping with trifluoroacetone and photocyclization , 1993 .

[60]  G. Kraus,et al.  Synthesis and Evaluation of a Pleurotin Analog , 1993 .

[61]  E. Silveira,et al.  Novel Cordiachromes Isolated from Auxemma oncocalyx , 1993 .

[62]  G. Kraus,et al.  The Development of a Direct Synthetic Route to Pleurotin , 1991 .

[63]  K. Hashimoto,et al.  Simple analogs of acromelic acid, which are highly active agonists of kainate type neuroexcitant , 1990 .

[64]  D. Hart,et al.  Free-radical cyclizations: application to the total synthesis of dl-pleurotin and dl-dihydropleurotin acid , 1989 .

[65]  D. Hart,et al.  Total synthesis of (.+-.)-pleurotin and (.+-.)-dihydropleurotin acid , 1988 .

[66]  T. Wallace,et al.  36-Dimethoxybenzocyclobutenone: a reagent for quinone synthesis , 1988 .

[67]  D. Hart,et al.  Preparation of the cde-ring system of pleurotin and geogenine via a stereoselective free radical cyclization , 1985 .

[68]  T. Durst,et al.  Stereoselectivity in the Diels-Alder reaction of phenyl- and oxy-substituted o-quinodimethanes , 1985 .

[69]  K. Johnson.  An Update. , 1984, Journal of food protection.

[70]  J. Dodd,et al.  Synthesis of the carbon framework of olivin , 1980 .

[71]  J. Staunton,et al.  Triacetic acid lactone as a polyketide synthon: synthesis of toralactone and polyketide-type anthracene derivatives , 1979 .

[72]  F. Sum,et al.  Stereoselective synthesis of β-substituted α,β-unsaturated esters by dialkylcuprate coupling to the enol phosphate of β-keto esters , 1979 .

[73]  W. C. Still,et al.  Rapid chromatographic technique for preparative separations with moderate resolution , 1978 .

[74]  F. Hauser,et al.  New synthetic methods for the regioselective annelation of aromatic rings: 1-hydroxy-2,3-disubstituted naphthalenes and 1,4-dihydroxy-2,3-disubstituted naphthalenes , 1978 .

[75]  H. Muxfeldt.  Syntheses in the Tetracycline Series , 1962 .

[76]  N. Yang,et al.  A NEW PHOTOCHEMICAL PRIMARY PROCESS, THE PHOTOCHEMICAL ENOLIZATION OF o-SUBSTITUTED BENZOPHENONES , 1961 .

[77]  W. J. Robbins,et al.  Antibiotic Substances from Basidiomycetes: I. Pleurotus griseus. , 1947, Proceedings of the National Academy of Sciences of the United States of America.