PD-1/PD-L1 pathway: current researches in cancer.
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[1] J. Lewin,et al. Pembrolizumab‐induced mucositis in a patient with recurrent hypopharynx squamous cell cancer , 2020, The Laryngoscope.
[2] G. Calin,et al. MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance. , 2019, Molecular aspects of medicine.
[3] Arash Salmaninejad,et al. PD‐1/PD‐L1 pathway: Basic biology and role in cancer immunotherapy , 2019, Journal of cellular physiology.
[4] S. Lantuejoul,et al. Programmed death ligand 1 immunohistochemistry in non-small cell lung carcinoma. , 2019, Journal of thoracic disease.
[5] Guang-Yu Lian,et al. LncRNA MALAT1 promotes tumorigenesis and immune escape of diffuse large B cell lymphoma by sponging miR-195. , 2019, Life sciences.
[6] Lin Xu,et al. Upregulation of long noncoding RNA SNHG20 promotes cell growth and metastasis in esophageal squamous cell carcinoma via modulating ATM‐JAK‐PD‐L1 pathway , 2019, Journal of cellular biochemistry.
[7] Elham Sameiyan,et al. The effect of medicinal plants on multiple drug resistance through autophagy: A review of in vitro studies , 2019, European journal of pharmacology.
[8] Yonghao Yang,et al. Efficacy and safety of nivolumab plus apatinib in advanced liver carcinosarcoma: a case report. , 2019, Immunotherapy.
[9] R. Chen,et al. JQ1, a BET-bromodomain inhibitor, inhibits human cancer growth and suppresses PD-L1 expression. , 2019 .
[10] A. Leha,et al. Monitoring efficacy of checkpoint inhibitor therapy in patients with non-small-cell lung cancer. , 2019, Immunotherapy.
[11] Ping Yang,et al. PD-L1 promotes colorectal cancer stem cell expansion by activating HMGA1-dependent signaling pathways. , 2019, Cancer letters.
[12] Xiaomo Wu,et al. Application of PD-1 Blockade in Cancer Immunotherapy , 2019, Computational and structural biotechnology journal.
[13] E. D. de Vries,et al. MAPK pathway activity plays a key role in PD‐L1 expression of lung adenocarcinoma cells , 2019, The Journal of pathology.
[14] H. Qiu,et al. FGFR2 Promotes Expression of PD-L1 in Colorectal Cancer via the JAK/STAT3 Signaling Pathway , 2019, The Journal of Immunology.
[15] I. Berindan‐Neagoe,et al. The Function of Non-Coding RNAs in Lung Cancer Tumorigenesis , 2019, Cancers.
[16] G. Gupta,et al. MAPK pathway: a potential target for the treatment of non-small-cell lung carcinoma. , 2019, Future medicinal chemistry.
[17] Xiang Yu,et al. Relationship between the expressions of PD-L1 and tumour-associated fibroblasts in gastric cancer , 2019, Artificial cells, nanomedicine, and biotechnology.
[18] Weili Zhao,et al. MiR155 sensitized B-lymphoma cells to anti-PD-L1 antibody via PD-1/PD-L1-mediated lymphoma cell interaction with CD8+T cells , 2019, Molecular Cancer.
[19] Jun Yu,et al. Autophagy inhibition enhances PD-L1 expression in gastric cancer , 2019, Journal of Experimental & Clinical Cancer Research.
[20] D. Spector,et al. MALAT1 long non-coding RNA and breast cancer , 2019, RNA biology.
[21] D. Ogata,et al. Systemic Immunotherapy for Advanced Cutaneous Squamous Cell Carcinoma , 2019, Current Treatment Options in Oncology.
[22] A. Evens,et al. The immune checkpoint molecules PD-1, PD-L1, TIM-3 and LAG-3 in diffuse large B-cell lymphoma , 2019, Oncotarget.
[23] W. Han,et al. Effects of different levels of soluble PD-L1 protein on the growth of Lewis lung cancer transplanted tumor. , 2019, Journal of biological regulators and homeostatic agents.
[24] A. Giobbie-Hurder,et al. Pembrolizumab plus trastuzumab in trastuzumab-resistant, advanced, HER2-positive breast cancer (PANACEA): a single-arm, multicentre, phase 1b-2 trial. , 2019, The Lancet. Oncology.
[25] Jingxia Li,et al. A Feedback Loop Formed by ATG7/Autophagy, FOXO3a/miR-145 and PD-L1 Regulates Stem-Like Properties and Invasion in Human Bladder Cancer , 2019, Cancers.
[26] Kun-Kun Wang,et al. MiR-21 Participates in the PD-1/PD-L1 Pathway-Mediated Imbalance of Th17/Treg Cells in Patients After Gastric Cancer Resection , 2018, Annals of Surgical Oncology.
[27] Yaoyao Zhou,et al. The Prognostic and Clinicopathological Roles of PD-L1 Expression in Colorectal Cancer: A Systematic Review and Meta-Analysis , 2019, Front. Pharmacol..
[28] Tao Xi,et al. MiR-873/PD-L1 axis regulates the stemness of breast cancer cells , 2019, EBioMedicine.
[29] Pramod Darvin,et al. PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications , 2019, Journal of oncology.
[30] S. Ansell,et al. Reverse signaling via PD-L1 supports malignant cell growth and survival in classical Hodgkin lymphoma , 2019, Blood Cancer Journal.
[31] J. Hao,et al. Recent Development of Wnt Signaling Pathway Inhibitors for Cancer Therapeutics , 2019, Current Oncology Reports.
[32] Zhigui Li,et al. PD‐1/PD‐L1 blockade rescue exhausted CD8+ T cells in gastrointestinal stromal tumours via the PI3K/Akt/mTOR signalling pathway , 2019, Cell proliferation.
[33] M. Iorio,et al. WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer , 2019, Oncogene.
[34] R. Pulido,et al. A Critical Insight into the Clinical Translation of PD-1/PD-L1 Blockade Therapy in Clear Cell Renal Cell Carcinoma , 2019, Current Urology Reports.
[35] E. Fuchs,et al. WNT Signaling in Cancer Immunosurveillance. , 2019, Trends in cell biology.
[36] Nina G. Steele,et al. Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer , 2018, Oncotarget.
[37] Gui-yuan Li,et al. YAP1-induced MALAT1 promotes epithelial–mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer , 2018, Oncogene.
[38] R. Huddart,et al. From Clinical Trials to Real-life Clinical Practice: The Role of Immunotherapy with PD-1/PD-L1 Inhibitors in Advanced Urothelial Carcinoma. , 2018, European urology oncology.
[39] Xu Li,et al. Synergistic Antitumor Effect on Bladder Cancer by Rational Combination of Programmed Cell Death 1 Blockade and CRISPR-Cas9-Mediated Long Non-Coding RNA Urothelial Carcinoma Associated 1 Knockout. , 2018, Human gene therapy.
[40] J. Wolchok,et al. Correction: Baseline Tumor Size Is an Independent Prognostic Factor for Overall Survival in Patients with Melanoma Treated with Pembrolizumab , 2018, Clinical Cancer Research.
[41] R. Jonsson,et al. Seminal immunologic discoveries with direct clinical implications: The 2018 Nobel Prize in Physiology or Medicine honours discoveries in cancer immunotherapy , 2018, Scandinavian journal of immunology.
[42] M. Boerries,et al. miR-146a Controls Immune Response in the Melanoma Microenvironment. , 2018, Cancer research.
[43] M. Atkins,et al. Current and emerging therapies for first-line treatment of metastatic clear cell renal cell carcinoma. , 2018, Cancer treatment reviews.
[44] Y. Shi,et al. ERα is a negative regulator of PD-L1 gene transcription in breast cancer. , 2018, Biochemical and biophysical research communications.
[45] J. Tagne,et al. NKX2-1-AS1 negatively regulates CD274/PD-L1, cell-cell interaction genes, and limits human lung carcinoma cell migration , 2018, Scientific Reports.
[46] P. Dong,et al. Tumor-Intrinsic PD-L1 Signaling in Cancer Initiation, Development and Treatment: Beyond Immune Evasion , 2018, Front. Oncol..
[47] J. Wolchok,et al. Baseline Tumor Size Is an Independent Prognostic Factor for Overall Survival in Patients with Melanoma Treated with Pembrolizumab , 2018, Clinical Cancer Research.
[48] J. Taube,et al. PD-L1 expression in medulloblastoma: an evaluation by subgroup , 2018, Oncotarget.
[49] S. He,et al. miR-33a inhibits cell proliferation and invasion by targeting CAND1 in lung cancer , 2018, Clinical and Translational Oncology.
[50] Katrien Van Roosbroeck,et al. miR-155 in cancer drug resistance and as target for miRNA-based therapeutics , 2018, Cancer and Metastasis Reviews.
[51] Arash Salmaninejad,et al. PD-1 and cancer: molecular mechanisms and polymorphisms , 2018, Immunogenetics.
[52] O. Liu,et al. Mitogen-activated protein kinase signaling pathway in oral cancer. , 2017, Oncology letters.
[53] G. Fontanini,et al. Role of microRNA-33a in regulating the expression of PD-1 in lung adenocarcinoma , 2017, Cancer Cell International.
[54] A. Balar,et al. Atezolizumab in invasive and metastatic urothelial carcinoma , 2017, Expert review of clinical pharmacology.
[55] T. Catela Ivković,et al. microRNAs as cancer therapeutics: A step closer to clinical application. , 2017, Cancer letters.
[56] Shengwei Liu,et al. PD-1/PD-L1 interaction up-regulates MDR1/P-gp expression in breast cancer cells via PI3K/AKT and MAPK/ERK pathways , 2017, Oncotarget.
[57] Y. Maehara,et al. A Comprehensive Analysis of Programmed Cell Death Ligand-1 Expression With the Clone SP142 Antibody in Non-Small-Cell Lung Cancer Patients. , 2017, Clinical lung cancer.
[58] H. Yao,et al. Rise of PD‐L1 expression during metastasis of colorectal cancer: Implications for immunotherapy , 2017, Journal of digestive diseases.
[59] B. Fox,et al. Timing of PD-1 Blockade Is Critical to Effective Combination Immunotherapy with Anti-OX40 , 2017, Clinical Cancer Research.
[60] B. Groner,et al. Jak Stat signaling and cancer: Opportunities, benefits and side effects of targeted inhibition , 2017, Molecular and Cellular Endocrinology.
[61] Huirong Shi,et al. Novel strategies to prevent the development of multidrug resistance (MDR) in cancer. , 2017, Oncotarget.
[62] T. Brummer,et al. MicroRNA-146a reduces MHC-II expression via targeting JAK/STAT-signaling in dendritic cells after stem cell transplantation , 2017, Leukemia.
[63] Robert Damoiseaux,et al. Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression , 2017, Cell reports.
[64] Daniela Massi,et al. PI3K-AKT-mTOR inhibition in cancer immunotherapy, redux. , 2017, Seminars in cancer biology.
[65] Tasuku Honjo,et al. Cancer immunotherapies targeting the PD-1 signaling pathway , 2017, Journal of Biomedical Science.
[66] Z. Zeng,et al. Co-expression of AFAP1-AS1 and PD-1 predicts poor prognosis in nasopharyngeal carcinoma , 2017, Oncotarget.
[67] A. McMahon,et al. Hedgehog Signaling: From Basic Biology to Cancer Therapy. , 2017, Cell chemical biology.
[68] D. Schwartz,et al. JAK–STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects , 2017, Drugs.
[69] D. Schwartz,et al. Erratum to: JAK–STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects , 2017, Drugs.
[70] Y. Naito,et al. The JAK/STAT pathway is involved in the upregulation of PD-L1 expression in pancreatic cancer cell lines. , 2017, Oncology reports.
[71] T. Powles,et al. A review on the evolution of PD-1/PD-L1 immunotherapy for bladder cancer: The future is now. , 2017, Cancer treatment reviews.
[72] Navneet Batra,et al. PI3K/Akt/mTOR Intracellular Pathway and Breast Cancer: Factors, Mechanism and Regulation. , 2017, Current pharmaceutical design.
[73] V. Boussiotis. Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway. , 2016, The New England journal of medicine.
[74] Wen-Qi Jiang,et al. PD-L1 is upregulated by EBV-driven LMP1 through NF-κB pathway and correlates with poor prognosis in natural killer/T-cell lymphoma , 2016, Journal of Hematology & Oncology.
[75] C. Cogoni,et al. MicroRNA in Control of Gene Expression: An Overview of Nuclear Functions , 2016, International journal of molecular sciences.
[76] L. Gandhi,et al. Biomarkers for the Clinical Use of PD-1/PD-L1 Inhibitors in Non-Small-Cell Lung Cancer: A Review. , 2016, JAMA oncology.
[77] F. Bazer,et al. Curcumin Suppresses Proliferation and Migration and Induces Apoptosis on Human Placental Choriocarcinoma Cells via ERK1/2 and SAPK/JNK MAPK Signaling Pathways1 , 2016, Biology of reproduction.
[78] Li Liu,et al. Up-regulation of LncRNA SNHG20 Predicts Poor Prognosis in Hepatocellular Carcinoma , 2016, Journal of Cancer.
[79] C. Jiang,et al. Regulation of PD-L1: a novel role of pro-survival signalling in cancer. , 2016, Annals of oncology : official journal of the European Society for Medical Oncology.
[80] Qiuyang Zhang,et al. PD-1, PD-L1 and PD-L2 expression in mouse prostate cancer. , 2016, American journal of clinical and experimental urology.
[81] S. Murphy,et al. Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor-κB to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer. , 2015, Cancer research.
[82] G. Calin,et al. PDL1 Regulation by p53 via miR-34 , 2015, Journal of the National Cancer Institute.
[83] G. Kristiansen,et al. The Immune Checkpoint Regulator PD-L1 Is Highly Expressed in Aggressive Primary Prostate Cancer , 2015, Clinical Cancer Research.
[84] Chuanhe Yang,et al. The Role of miR‐21 in Cancer , 2015, Drug development research.
[85] R. Mashima. Physiological roles of miR‐155 , 2015, Immunology.
[86] Z. Zeng,et al. Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma , 2015, Oncotarget.
[87] C. Rudd,et al. ADAP and SKAP55 deficiency suppresses PD-1 expression in CD8+ cytotoxic T lymphocytes for enhanced anti-tumor immunotherapy , 2015, EMBO molecular medicine.
[88] P. Hersey,et al. Inducible but Not Constitutive Expression of PD-L1 in Human Melanoma Cells Is Dependent on Activation of NF-κB , 2015, PloS one.
[89] N. Matsumura,et al. IFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer , 2015, British Journal of Cancer.
[90] G. Freeman,et al. Interferon-γ-induced activation of JAK1 and JAK2 suppresses tumor cell susceptibility to NK cells through upregulation of PD-L1 expression , 2015, Oncoimmunology.
[91] Ren-Jie Wang,et al. MicroRNA-873 (MiRNA-873) Inhibits Glioblastoma Tumorigenesis and Metastasis by Suppressing the Expression of IGF2BP1 , 2015, The Journal of Biological Chemistry.
[92] Yan Liu,et al. PD-1/PD-L1 pathway in non-small-cell lung cancer and its relation with EGFR mutation , 2015, Journal of Translational Medicine.
[93] S. Kaech,et al. The transcription factor FoxO1 sustains expression of the inhibitory receptor PD-1 and survival of antiviral CD8(+) T cells during chronic infection. , 2014, Immunity.
[94] Lieping Chen,et al. Inducible Expression of B7-H1 (PD-L1) and Its Selective Role in Tumor Site Immune Modulation , 2014, Cancer journal.
[95] Haifeng Liu,et al. Activator protein 1 suppresses antitumor T-cell function via the induction of programmed death 1 , 2012, Proceedings of the National Academy of Sciences.
[96] R. Ahmed,et al. Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. , 2011, Immunity.
[97] D. Iliopoulos,et al. The negative costimulatory molecule PD‐1 modulates the balance between immunity and tolerance via miR‐21 , 2011, European journal of immunology.
[98] G. Pinkus,et al. Programmed Death Ligand 1 Is Expressed by Non–Hodgkin Lymphomas and Inhibits the Activity of Tumor-Associated T Cells , 2011, Clinical Cancer Research.
[99] M. Azuma,et al. Blockade of B7-H1 or B7-DC induces an anti-tumor effect in a mouse pancreatic cancer model. , 2009, International journal of oncology.
[100] S. Rosenberg,et al. Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. , 2009, Blood.
[101] H. Friess,et al. Clinical significance and regulation of the costimulatory molecule B7-H1 in pancreatic cancer. , 2008, Cancer letters.
[102] Koichiro Matsumoto,et al. Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers , 2007, Cancer Immunology, Immunotherapy.
[103] G. Freeman,et al. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection , 2007, Nature Immunology.
[104] B. Neel,et al. The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. , 2003, Trends in biochemical sciences.
[105] E. Birney,et al. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs , 2002, Nature.
[106] T. Honjo,et al. Induced expression of PD‐1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. , 1992, The EMBO journal.
[107] M. Sakamoto,et al. Characterization of spatial distribution of tumor-infiltrating CD8+ T cells refines their prognostic utility for pancreatic cancer survival , 2019, Modern Pathology.
[108] C. Rudd,et al. Small-Molecule Inhibition of PD-1 Transcription Is an Effective Alternative to Antibody Blockade in Cancer Therapy. , 2018, Cancer research.
[109] Jackeline Agorreta,et al. A Combined PD-1/C5a Blockade Synergistically Protects against Lung Cancer Growth and Metastasis. , 2017, Cancer discovery.
[110] Charles S Bond,et al. The ins and outs of lncRNA structure: How, why and what comes next? , 2016, Biochimica et biophysica acta.
[111] Yu Yao,et al. Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway. , 2015, Trends in molecular medicine.
[112] Xijian Zhou,et al. Inhibition of lactate dehydrogenase A by microRNA-34a resensitizes colon cancer cells to 5-fluorouracil. , 2015, Molecular medicine reports.
[113] Mary Collins,et al. The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. , 2002, Annual review of immunology.