论文信息 - Decreasing incidence of pregnancy by decreasing CD4 cell count in HIV-infected women in Côte d'Ivoire: a 7-year cohort study

Decreasing incidence of pregnancy by decreasing CD4 cell count in HIV-infected women in Côte d'Ivoire: a 7-year cohort study

In a cohort study of women of childbearing age in Abidjan, Côte d'Ivoire, we followed 473 HIV-infected women for 1551 person-years, and found that the incidence of pregnancy and livebirth decreased with decreasing CD4 cell counts. This has consequences in terms of scaling-up strategies for highly active antiretroviral therapy (HAART). Women who need HAART will be less likely than those who do not to be recruited into prenatal care facilities.

[1] L. Shafer,et al. HIV-1 disease progression and fertility: the incidence of recognized pregnancy and pregnancy outcome in Uganda , 2004, AIDS.

[2] R. Salamon,et al. Pattern of bacterial diseases in a cohort of HIV-1 infected adults receiving cotrimoxazole prophylaxis in Abidjan, Côte d'Ivoire , 2003, AIDS.

[3] M. Hudgens,et al. Twenty-four month efficacy of a maternal short-course zidovudine regimen to prevent mother-to-child transmission of HIV-1 in West Africa , 2002, AIDS.

[4] F. Dabis,et al. Incidence of pregnancies among African HIV-infected women, Abidjan, 1995-2000. , 2001, AIDS.

[5] N. Sewankambo,et al. Population-based study of fertility in women with HIV-1 infection in Uganda , 1998, The Lancet.

[6] N. Badi,et al. Fertility rates in 238 HIV-1-seropositive women in Zaire followed for 3 years post-partum. , 1991, AIDS.